Abstract：
:The LTP Program is a stimulation, acquisition and on-line analysis program for studying long-term potentiation (LTP), long-term depression (LTD), and stimulus-evoked synaptic responses in general. The program is freely available from the website: www.ltp-program.com. It is a 32-bit DOS program that runs on Windows 3/95/98 computers having a Pico Technologies ADC-42, Axon Instruments' Digidata 1200, or Scientific Solution's Labmaster acquisition board. The program records two channels of activity in extracellular, current- or voltage clamp modes. It acquires < or =1,000,000 samples per sweep, and has extracellular dual pathway stimulation and epoch-like intracellular stimulation. Basic protocols include slow alternating dual pathway stimulation. LTP is induced by single train, theta burst, or primed burst stimulation. LTD is induced using fast repetitive 1 pulse sweeps (< or =2 Hz). The program analyzes all stimulus-evoked synaptic responses in both acquisition channels. Analyzes include: slope, peak amplitude/latency, population spike amplitude/latency, average amplitude, duration, area, rise time, decay time, coastline, cell resistance and patch electrode series resistance. Sweeps can be averaged and digitally filtered. Trains can be analyzed by measuring the responses of all pulses relative to the baseline of the first pulse. Stimulus artifacts can be automatically removed for accurate determination of synaptic areas and peaks during a train.
journal_name
J Neurosci Methodsjournal_title
Journal of neuroscience methodsauthors
Anderson WW,Collingridge GLdoi
10.1016/s0165-0270(01)00374-0subject
Has Abstractpub_date
2001-07-15 00:00:00pages
71-83issue
1eissn
0165-0270issn
1872-678Xpii
S0165-0270(01)00374-0journal_volume
108pub_type
杂志文章abstract：BACKGROUND:In this paper exploitation of correlation between post-movement beta rebound in EEG and blood oxygenation level dependent (BOLD) in fMRI is addressed. Brain studies do not reveal any clear relationship between synchronous neuronal activity and BOLD signal. Simultaneous recording of EEG and fMRI provides a gr...
journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
pub_type： 杂志文章,评审
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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doi：10.1016/j.jneumeth.2017.07.027
更新日期：2017-11-01 00:00:00
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journal_title：Journal of neuroscience methods
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doi：10.1016/0165-0270(88)90046-5
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journal_title：Journal of neuroscience methods
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doi：10.1016/s0165-0270(00)00221-1
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
pub_type： 杂志文章,评审
doi：10.1016/0165-0270(94)00081-q
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journal_title：Journal of neuroscience methods
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journal_title：Journal of neuroscience methods
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更新日期：2019-11-01 00:00:00
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journal_title：Journal of neuroscience methods
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pub_type： 杂志文章
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