Quantitative determination of C-polysaccharide in Streptococcus pneumoniae capsular polysaccharides by use of high-performance anion-exchange chromatography with pulsed amperometric detection.

abstract：:Spores of the genus Bacillus have been used for a long time as probiotics for oral bacteriotherapy both in humans and in animals. Spores are also employed in a veterinary vaccine against anthrax. Despite this long lasting and extensive use, the specific contribution of spores to the beneficial effects of probiotics an...

journal_title：Vaccine

authors： Oggioni MR,Ciabattini A,Cuppone AM,Pozzi G

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:The goal of this study was to evaluate whether a live attenuated poliovirus vaccine (OPV) has clinically relevant interfering effect with non-polio infections causing otitis media in young children. METHODS:Open trial in which the intervention group (64 children) received OPV at the age of 2, 3, 6 and 12 mo...

journal_title：Vaccine

authors： Seppälä E,Viskari H,Hoppu S,Honkanen H,Huhtala H,Simell O,Ilonen J,Knip M,Hyöty H

更新日期：2011-11-03 00:00:00

abstract：:Sin Nombre virus (SNV; family Bunyaviridae, genus Hantavirus) causes a hemorrhagic fever known as hantavirus pulmonary syndrome (HPS) in North America. There have been approximately 200 fatal cases of HPS in the United States since 1993, predominantly in healthy working-age males (case fatality rate 35%). There are no...

journal_title：Vaccine

authors： Hooper JW,Josleyn M,Ballantyne J,Brocato R

更新日期：2013-09-13 00:00:00

abstract：BACKGROUND:Persons with primary immunodeficiency disorders (PIDD) who receive oral poliovirus vaccine (OPV) or are household contacts of OPV recipients are at risk of excreting immunodeficiency-associated vaccine-derived polioviruses (iVDPVs). iVDPVs can be transmitted and cause paralytic polio. The objective of this s...

journal_title：Vaccine

authors： Sazzad HM,Rainey JJ,Mach O,Sutter R,Diordista S,Kawser CA,Mobarak R,Alam D,Chowdhury MA,Hossain MJ,Hasan AS,Luby SP

更新日期：2012-08-03 00:00:00

abstract：:A mailed questionnaire survey was undertaken in old people's (nursing and residential) homes in Carmarthenshire, UK to determine the influenza vaccine uptake during the 1998/99 season. Out of the total 60 questionnaires circulated, response was received from 47 homes giving an overall response rate of 78%. Amongst the...

journal_title：Vaccine

authors： Gupta A,Morris G,Thomas P,Hasan M

更新日期：2000-05-22 00:00:00

abstract：BACKGROUND:Combination highly active antiretroviral therapy (HAART) has significantly decreased HIV-1 related morbidity and mortality globally transforming HIV into a controllable condition. HAART has a number of limitations though, including limited access in resource constrained countries, which have driven the searc...

journal_title：Vaccine

authors： Vardas E,Stanescu I,Leinonen M,Ellefsen K,Pantaleo G,Valtavaara M,Ustav M,Reijonen K

更新日期：2012-06-08 00:00:00

abstract：BACKGROUND:As part of the U.S. Department of Health and Human Services (HHS) Pandemic Influenza Plan preparedness and response strategy, the National Pre-Pandemic Influenza Vaccine Stockpile (NPIVS) program was established by the Biomedical Advanced Research and Development Authority (BARDA) in 2005 with the goal of bu...

journal_title：Vaccine

authors： Oshansky CM,Zhou J,Gao Y,Schweinle JE,Biscardi K,DeBeauchamp J,Pavetto C,Wollish A,BRITE Study Coordination Team.,Webby RJ,Cioce V,Donis RO,Bright RA

更新日期：2019-01-14 00:00:00

abstract：:The relevance of CD4+T-cells, viral load and age in the immunological response to influenza infection and vaccination in HIV-1 infected individuals has previously been pointed out. Our study aimed at assessing, in the setting of 2009 A(H1N1)pdm09 influenza vaccination, whether quantification of activation-induced deam...

journal_title：Vaccine

authors： Cagigi A,Pensieroso S,Ruffin N,Sammicheli S,Thorstensson R,Pan-Hammarström Q,Hejdeman B,Nilsson A,Chiodi F

更新日期：2013-04-26 00:00:00

abstract：:A short-term toxicity study was performed to investigate local reactions and haematological changes after intramuscular (i.m.) injection of meningococcal vaccine with a concentration of 25 or 50 micrograms protein ml-1. In these meningococcal vaccines up to 75 micrograms Zwittergent ml-1 was used to form a protein-det...

journal_title：Vaccine

authors： Speijers GJ,Danse LH,Beuvery EC,Derks HJ,Vos JG

更新日期：1988-10-01 00:00:00

abstract：:Autovaccines are therapeutic vaccines manufactured from a disease causing micro-organism for individual treatment of patients, animals, or sometimes herds to treat chronic or recurrent infections. Despite the common use of autovaccines in veterinary medicine, their mechanism of action, i.e. the immunologic effector me...

journal_title：Vaccine

authors： Nolte O,Morscher J,Weiss HE,Sonntag H

更新日期：2001-04-30 00:00:00

abstract：:The bacillus Calmette Guérin (BCG) vaccine, the only licensed vaccine against TB, displays partial and variable efficacy, thus making the exploitation of novel vaccination strategies a major priority. Most of the current vaccines in pre-clinical or clinical development are based on the induction of T cells recognizing...

journal_title：Vaccine

authors： Larrouy-Maumus G,Layre E,Clark S,Prandi J,Rayner E,Lepore M,de Libero G,Williams A,Puzo G,Gilleron M

更新日期：2017-03-07 00:00:00

abstract：:Human papillomavirus (HPV) infection causes cervical cancer and genital warts. Young women (1106) were randomized to receive one of three formulations of a quadrivalent HPV (Types 6/11/16/18) L1 virus-like particle (VLP) vaccine or one of two placebo formulations. The goal was to assess vaccine safety and immunogenici...

journal_title：Vaccine

authors： Villa LL,Ault KA,Giuliano AR,Costa RL,Petta CA,Andrade RP,Brown DR,Ferenczy A,Harper DM,Koutsky LA,Kurman RJ,Lehtinen M,Malm C,Olsson SE,Ronnett BM,Skjeldestad FE,Steinwall M,Stoler MH,Wheeler CM,Taddeo FJ,Yu J,

更新日期：2006-07-07 00:00:00

abstract：:Vaccine development strategies have often utilized recombinant envelope glycoproteins which usually generate strong humoral immune responses but which do not generate strong cytotoxic T lymphocytes (CTL). A recent novel experimental vaccination approach involves the technology known as nucleic acid immunization in whi...

journal_title：Vaccine

authors： Ugen KE,Boyer JD,Wang B,Bagarazzi M,Javadian A,Frost P,Merva MM,Agadjanyan MG,Nyland S,Williams WV,Coney L,Ciccarelli R,Weiner DB

更新日期：1997-06-01 00:00:00

abstract：:The hepatitis B virus (HBV) has infected more than 2000 million persons alive today and 350 million persons are chronically infected carriers of the virus, at high risk of death from active hepatitis, cirrhosis and primary hepatocellular cancer. Each year approximately 1 million people die from the acute and chronic s...

journal_title：Vaccine

authors： Kane M

更新日期：1995-01-01 00:00:00

abstract：:This study compared responses of bison calves to 10(10)CFU of Brucella abortus strain RB51 (SRB51) delivered by parenteral or ballistic methods. Two types of biobullet payloads were evaluated; compacted SRB51 pellets or SRB51 encapsulated in photopolymerized poly(ethylene glycol) hydrogels. Bison were vaccinated with ...

journal_title：Vaccine

authors： Olsen SC,Christie RJ,Grainger DW,Stoffregen WS

更新日期：2006-02-27 00:00:00

abstract：:Recently avian influenza A viruses of the H5N1 subtype were shown to infect humans in the Hong Kong area, resulting in the death of six people. Although these viruses did not efficiently spread amongst humans, these events illustrated that influenza viruses of subtypes not previously detected in humans could be at the...

journal_title：Vaccine

authors： Rimmelzwaan GF,Claas EC,van Amerongen G,de Jong JC,Osterhaus AD

更新日期：1999-03-17 00:00:00

abstract：:As companies, countries, and governments consider investments in vaccine production for routine immunization and outbreak response, understanding the complexity and cost drivers associated with vaccine production will help to inform business decisions. Leading multinational corporations have good understanding of the ...

journal_title：Vaccine

authors： Plotkin S,Robinson JM,Cunningham G,Iqbal R,Larsen S

更新日期：2017-07-24 00:00:00

abstract：:Since children with chronic diseases represent a primary target for immunization strategies, it is important that their immunization coverage and timeliness of vaccines is optimal. We performed a study to measure immunization coverage and timeliness of vaccines in children with type 1 diabetes, HIV infection, Down syn...

journal_title：Vaccine

authors： Pandolfi E,Carloni E,Marino MG,Ciofi degli Atti ML,Gesualdo F,Romano M,Giannattasio A,Guarino A,Carloni R,Borgia P,Volpe E,Perrelli F,Pizzuti R,Tozzi AE

更新日期：2012-07-20 00:00:00

abstract：BACKGROUND:Measles is a highly infectious respiratory disease which causes 122,000 deaths annually. Although measles vaccine is extremely safe and effective, vaccine coverage could be improved by a vaccine that is more easily administered and transported. We developed an inhalable dry powder measles vaccine (MVDP) and ...

journal_title：Vaccine

authors： MVDP author group.,Cape S,Chaudhari A,Vaidya V,Mulay R,Agarkhedkar S,Shermer C,Collins M,Anderson R,Agarkhedkar S,Kulkarni PS,Winston S,Sievers R,Dhere RM,Gunale B,Powell K,Rota PA,Papania M

更新日期：2014-11-28 00:00:00

abstract：:In this article, we review three mechanisms that contribute to sustaining serum antibody levels: (i) long-lived plasma cells; (ii) persisting or cross-reactive antigen, and (iii) polyclonal activation of all memory B cells. We also present a quantitative analysis of the secondary immune response that reveals the relat...

journal_title：Vaccine

authors： Traggiai E,Puzone R,Lanzavecchia A

更新日期：2003-06-01 00:00:00

abstract：:To prevent premature dismissal of promising vaccine programs, it is critical to determine if lack of efficacy in the field is due to allele specific-efficacy, rather than to the lack of immunogenicity of the candidate antigen. Here we use samples collected during a field trial of the AMA1-based FMP2.1/AS02A malaria va...

journal_title：Vaccine

authors： Ouattara A,Niangaly A,Adams M,Coulibaly D,Kone AK,Traore K,Laurens MB,Tolo Y,Kouriba B,Diallo DA,Doumbo OK,Plowe CV,Djimdé A,Thera MA,Laufer MK,Takala-Harrison S,Silva JC

更新日期：2020-07-31 00:00:00

abstract：:The 23-valent pneumococcal vaccine has unequal effectiveness in splenectomised patients. We performed a longitudinal study (2005-2008) whose main objective was to characterize the profile of non-responders among splenectomised patients treated at our institution and identify potential predictive indicators of the resp...

journal_title：Vaccine

authors： Llupià A,Vilella A,Costas L,Díez C,Torres F,Yagüe J,Massó M,Muñoz A,Mensa J

更新日期：2012-03-16 00:00:00

abstract：:Based on the reactivities of monoclonal antibodies, we previously reported that 25 Japanese encephalitis (JE) virus strains fell into five antigenic groups: Nakayama, Beijing-1, Kamiyama, 691004 and Muar. In the present study, we produced monoclonal antibodies against the Beijing-1 strain and obtained the Beijing-1 gr...

journal_title：Vaccine

authors： Satake Y,Hasegawa H,Yoshida M,Kobayashi Y

更新日期：1994-06-01 00:00:00

abstract：:Persistent infection by high risk genotypes of human papillomavirus (HPV) is the cause of cervical cancer, which remains one of the most common cancers among women worldwide. In addition, there is a growing appreciation that high risk HPVs are associated with a number of other cancers including anogenital cancers as w...

journal_title：Vaccine

authors： Wick DA,Webb JR

更新日期：2011-10-13 00:00:00

abstract：:A safe, effective and accessible preventive vaccine is our best long-term hope for the control of the HIV/AIDS pandemic. The first phase I trial of an HIV vaccine was conducted in the US in 1987. Since then, >30 candidate vaccines have been tested in over 60 phase I/II clinical trials, involving >8000 healthy human vo...

journal_title：Vaccine

authors： Esparza J,Osmanov S,Pattou-Markovic C,Touré C,Chang ML,Nixon S

更新日期：2002-05-06 00:00:00

abstract：:The mechanisms of protection elicited by smallpox vaccine in humans have not been delineated. Dendritic cells (DCs) are the most potent of professional antigen presenting cells which on activation modulate both innate and adaptive immune responses. Immunogenic proteins of vaccinia virus have been identified with prote...

journal_title：Vaccine

authors： Agrawal S,Gupta S,Agrawal A

更新日期：2009-01-01 00:00:00

abstract：:At present, the seed viruses for the manufacture of licensed seasonal inactivated influenza vaccines in the United States are derived from primary egg isolates as a result of concerns associated with adventitious agents. According to the prevailing view, the passage of influenza viruses through eggs serves as a filter...

journal_title：Vaccine

authors： Murata H,Macauley J,Lewis AM Jr,Peden K

更新日期：2011-04-12 00:00:00

abstract：:Polymeric nanoparticles (NPs) of poly (lactic-co-glycolic) acid (PLGA) possess adjuvant properties. To date, there are few studies exploring their application as antigen carriers for vaccination of fish. This study presents a preclinical assessment of the early innate and adaptive immune responses in Atlantic salmon f...

journal_title：Vaccine

authors： Fredriksen BN,Sævareid K,McAuley L,Lane ME,Bøgwald J,Dalmo RA

更新日期：2011-10-26 00:00:00

abstract：:Recombinant antigens from the oncosphere stage of the parasite Taenia solium were expressed in Escherichia coli. The TSOL16, TSOL45-1A and TSOL45-1B recombinant antigens, each consisting of fibronectin type III (FnIII) domain S, were produced as fusion proteins with glutathione S-transferase (GST) and maltose binding ...

journal_title：Vaccine

authors： Gauci CG,Jayashi CM,Gonzalez AE,Lackenby J,Lightowlers MW

更新日期：2012-06-06 00:00:00

abstract：:A devastating disease spread by mosquitoes with high-efficiency, malaria imposes an enormous burden for which no licensed vaccine currently exists. Although the genome complexity of the parasite has made vaccine development tenuous, an effective malaria vaccine would be a valuable tool for control, elimination and eve...

journal_title：Vaccine

authors： Palacpac NM,Arisue N,Tougan T,Ishii KJ,Horii T

更新日期：2011-08-11 00:00:00