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Isolation of anti-Beijing-1 group-specific monoclonal antibody and antigenic analysis of Japanese encephalitis viruses in India.

Abstract：

:Based on the reactivities of monoclonal antibodies, we previously reported that 25 Japanese encephalitis (JE) virus strains fell into five antigenic groups: Nakayama, Beijing-1, Kamiyama, 691004 and Muar. In the present study, we produced monoclonal antibodies against the Beijing-1 strain and obtained the Beijing-1 group-specific antibody, designated BEGMA 1. Furthermore, antigenic comparison of the seven JE virus strains isolated in India was performed by using BEGMA 1 and other group-specific antibodies. The results showed that six strains fell into the Kamiyama group to which the currently prevalent strains in Japan belong.

journal_name

Vaccine

journal_title

Vaccine

authors

Satake Y,Hasegawa H,Yoshida M,Kobayashi Y

doi

10.1016/0264-410x(94)90222-4

subject

Has Abstract

pub_date

1994-06-01 00:00:00

pages

723-6

issue

8

eissn

0264-410X

issn

1873-2518

pii

0264-410X(94)90222-4

journal_volume

12

pub_type

杂志文章

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