Changes in prevalence of influenza vaccination and strength of association of factors predicting influenza vaccination over time--results of two population-based surveys.

abstract：:Antibodies have the potential to be therapeutic reagents for malaria. Here we describe the production of a novel phage antibody display library against the C-terminal 19kDa region of the Plasmodium yoelii YM merozoite surface protein-1 (MSP1(19)). In vivo studies against homologous lethal malaria challenge show an ant...

journal_title：Vaccine

authors： Vukovic P,Chen K,Qin Liu X,Foley M,Boyd A,Kaslow D,Good MF

更新日期：2002-06-21 00:00:00

abstract：:Clinical and serum antibody responses following intramuscular injection of two formulations of Salmonella typhi Vi capsular polysaccharide (Vi) were assessed in a double-blind evaluation. Healthy adults were randomly assigned to receive a 25 micrograms dose of liquid (Vi-Liq; n = 182) or freeze-dried Vi vaccine (Vi-Ly...

journal_title：Vaccine

authors： Keitel WA,Bond NL,Zahradnik JM,Cramton TA,Robbins JB

更新日期：1994-01-01 00:00:00

abstract：:Vaccine development strategies have often utilized recombinant envelope glycoproteins which usually generate strong humoral immune responses but which do not generate strong cytotoxic T lymphocytes (CTL). A recent novel experimental vaccination approach involves the technology known as nucleic acid immunization in whi...

journal_title：Vaccine

authors： Ugen KE,Boyer JD,Wang B,Bagarazzi M,Javadian A,Frost P,Merva MM,Agadjanyan MG,Nyland S,Williams WV,Coney L,Ciccarelli R,Weiner DB

更新日期：1997-06-01 00:00:00

abstract：:Immunologically based fertility control vaccines against zona pellucida (ZP) proteins are being developed in New Zealand for biocontrol of the brushtail possum (Trichosurus vulpecula), an introduced Australian marsupial pest. We have shown that immunization of female possums with recombinant possum ZP3 protein (rZP3) ...

journal_title：Vaccine

authors： Cui X,Duckworth JA,Molinia FC,Cowan PE

更新日期：2010-02-10 00:00:00

abstract：:Gag-CD8+ T cell responses are associated with immune control of HIV infection. Since during HIV infection Nef impairs T cell responses, we evaluated whether deletion of nef from a non-infectious HIV DNA vaccine (Delta4 Nef+), creating Delta5 Nef(-), would affect its immunogenicity. When compared with Delta4, mice inje...

journal_title：Vaccine

authors： Arrode G,Hegde R,Jin Y,Singh DK,Narayan O,Chebloune Y

更新日期：2008-07-23 00:00:00

abstract：:Tuberculosis caused by infection with Mycobacterium tuberculosis or Mycobacterium bovis remains one of the most important infectious diseases of man and animals. The current vaccine M. bovis Calmette-Guérin (BCG) demonstrates variable efficacy and so a more robust strategy to either replace, or more likely supplement ...

journal_title：Vaccine

authors： Logan KE,Chambers MA,Hewinson RG,Hogarth PJ

更新日期：2005-12-01 00:00:00

abstract：:Cationic antimicrobial peptides (CAMPs) are active defence components of the innate immune system. Several artificial CAMPs have been designed as antibiotic peptide therapeutics, but none have been reported to exert adjuvant activity in animal models. Here we show for the first time that an artificial CAMP, KLKLLLLLKL...

journal_title：Vaccine

authors： Fritz JH,Brunner S,Birnstiel ML,Buschle M,Gabain Av,Mattner F,Zauner W

更新日期：2004-09-03 00:00:00

abstract：:B. pseudomallei is the cause of melioidosis, a serious an often fatal disease of humans and animals. The closely related bacterium B. mallei, which cases glanders, is considered to be a clonal derivative of B. pseudomallei. Both B. pseudomallei and B. mallei were evaluated by the United States and the former USSR as p...

journal_title：Vaccine

authors： Titball RW,Burtnick MN,Bancroft GJ,Brett P

更新日期：2017-10-20 00:00:00

abstract：:In order to evaluate the immunogenicity, safety, and tolerability of the MF-59 adjuvanted seasonal influenza vaccine in children and adolescents with juvenile idiopathic arthritis (JIA) treated with different anti-rheumatic drugs, 60 pediatric patients with JIA (30 treated with disease-modifying anti-rheumatic drugs [...

journal_title：Vaccine

authors： Dell'Era L,Corona F,Daleno C,Scala A,Principi N,Esposito S

更新日期：2012-01-20 00:00:00

abstract：:The role of the defect in erythritol catabolism in the attenuated virulence of Brucella abortus B19 vaccine strain in mice was investigated by means of five different strains: (i) the erythritol sensitive B19 vaccine strain; (ii) a natural erythritol tolerant (NET) mutant obtained spontaneously from B19; (iii) an eryt...

journal_title：Vaccine

authors： Sangari FJ,Grilló MJ,Jiménez De Bagüés MP,González-Carreró MI,García-Lobo JM,Blasco JM,Agüero J

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Typhoid fever remains a major public health problem in low- and middle-income countries where children aged 2-14 years bear the greatest burden. Vi polysaccharide is poorly immunogenic in children <2 years of age, and protection in adults is modest. The limitations of Vi polysaccharide vaccines can be overco...

journal_title：Vaccine

authors： Capeding MR,Teshome S,Saluja T,Syed KA,Kim DR,Park JY,Yang JS,Kim YH,Park J,Jo SK,Chon Y,Kothari S,Yang SY,Ham DS,Ryu JH,Hwang HS,Mun JH,Lynch JA,Kim JH,Kim H,Excler JL,Sahastrabuddhe S

更新日期：2018-06-18 00:00:00

abstract：:The need to avoid using primates has prompted the replacement of primary monkey kidney cells (PMKC) as a substrate for oral polio vaccine (OPV) production. Here, we report on OPV produced on MRC-5 cells using an industrial process capable of producing over 1 billion doses. All serotypes produced on MRC-5 cells proved ...

journal_title：Vaccine

authors： Prikazsky V,Leroux-Roels G,Van Damme P,Safary A,Colau B,Duchene M

更新日期：2005-07-21 00:00:00

abstract：:Despite a critical need for a respiratory syncytial virus (RSV) vaccine and decades of development efforts, a vaccine to protect infants, elderly, and other at-risk populations from RSV infection remains elusive. We have previously generated a new, live-attenuated vaccine candidate against RSV using rational, computer...

journal_title：Vaccine

authors： Mueller S,Stauft CB,Kalkeri R,Koidei F,Kushnir A,Tasker S,Coleman JR

更新日期：2020-03-23 00:00:00

abstract：:A number of clinical reports of drug interactions with influenza vaccine have been made. We hypothesized that CYP3A4 activity would decrease following influenza immunization. Fifteen healthy subjects had erythromycin breath tests (ERMBT) and influenza antibody titer hemagglutinin inhibition assay (HIA) before and afte...

journal_title：Vaccine

authors： Hayney MS,Hammes RJ,Fine JP,Bianco JA

更新日期：2001-12-12 00:00:00

abstract：BACKGROUND:Surveillance data on invasive pneumococcal disease (IPD) in Denmark (1999-2014) was analysed regarding the incidence and age-distribution due to ten selected non-PCV serotypes (10-Non-PCV). The effect of PCV-7 and PCV-13 vaccines on the 10-Non-PCV IPD incidence was examined. METHODS:IPD cases caused by sero...

journal_title：Vaccine

authors： Slotved HC,Dalby T,Hoffmann S

更新日期：2016-02-03 00:00:00

abstract：:The Indian rhesus macaque is the established animal model for HIV infection and vaccine research. Growing evidence suggests that the more readily available Chinese rhesus macaque may be a more relevant option. As increasing numbers of novel Chinese rhesus MHC alleles are reported, we decided to explore potential HIV v...

journal_title：Vaccine

authors： Liao Q,Strong AJ,Liu Y,Liu Y,Meng P,Fu Y,Touzjian N,Shao Y,Zhao Z,Lu Y

更新日期：2012-02-21 00:00:00

abstract：:Meningococci bind human fH to down-regulate complement, which enhances survival of the bacteria in serum. A major fH ligand is the vaccine candidate, factor H-binding protein (fHbp). Although fHbp has been considered an essential meningococcal virulence factor, rarely, invasive isolates with absent fHbp genes or frame...

journal_title：Vaccine

authors： Giuntini S,Vu DM,Granoff DM

更新日期：2013-08-28 00:00:00

abstract：:The effect of passively transferred RSV immune serum on the antibody response to a single dose of purified RSV fusion (F) and large (G) glycoproteins was studied in cotton rats. Passively transferred antibody that achieved serum antibody levels similar to those seen in newborn human infants resulted in a seven- to eig...

journal_title：Vaccine

authors： Murphy BR,Prince GA,Collins PL,Hildreth SW,Paradiso PR

更新日期：1991-03-01 00:00:00

abstract：:The potency of genetic immunization observed in the mouse has demonstrated the utility of DNA vaccines to induce cell-mediated and humoral immune responses. However, it has been relatively difficult to generate comparable responses in non-rodent species. The use of molecular adjuvants may increase the magnitude of the...

journal_title：Vaccine

authors： Maue AC,Waters WR,Palmer MV,Nonnecke BJ,Minion FC,Brown WC,Norimine J,Foote MR,Scherer CF,Estes DM

更新日期：2007-06-11 00:00:00

abstract：:Enterovirus 71 (EV71) causes seasonal epidemics of hand-foot-and-mouth disease associated with fatal neurological complications in young children, and several major outbreaks have occurred recently. This study developed an effective antiviral agent by transforming the gene for VP1 protein, a previously defined epitope...

journal_title：Vaccine

authors： Chen HF,Chang MH,Chiang BL,Jeng ST

更新日期：2006-04-05 00:00:00

abstract：BACKGROUND:Worldwide coverage of hepatitis B (HB) vaccination is increasing. This should be considered when determining the best strategy for catch-up HB vaccination in migrant children, who rarely have written proof of past immunizations. This study aimed to estimate HB vaccine protection, chronic HB prevalence and to...

journal_title：Vaccine

authors： Fougère Y,El Houss S,Suris JC,Rouvenaz-Defago S,Miletto D,Von der Weid L,Willen F,Williams-Smith JA,Gehri M,Crisinel PA

更新日期：2018-07-16 00:00:00

abstract：:Measles remains a major cause of worldwide infant mortality despite the use of current live attenuated vaccines. New approaches to measles virus (MV) vaccine development are critical to interrupt the spread of MV. In this study, we report the results using a DNA vaccine expressing a fusion of the measles hemagglutinin...

journal_title：Vaccine

authors： Green TD,Newton BR,Rota PA,Xu Y,Robinson HL,Ross TM

更新日期：2001-10-12 00:00:00

abstract：BACKGROUND:Vaccination against Haemophilus influenzae type b (Hib) is included in routine pediatric immunization schedule in the United States. Previous vaccine shortages have created the need for additional options for Hib vaccination. METHODS:This phase III, randomized, multi-centered study (NCT01000974) evaluated t...

journal_title：Vaccine

authors： Klein NP,Abu-Elyazeed R,Cornish M,Leonardi ML,Weiner LB,Silas PE,Grogg SE,Varman M,Frenck RW,Cheuvart B,Baine Y,Miller JM,Leyssen M,Mesaros N,Roy-Ghanta S

更新日期：2017-06-16 00:00:00

abstract：OBJECTIVE:Prophylactic antipyretic use during pediatric vaccination is common. This study assessed whether paracetamol or ibuprofen prophylaxis interfere with immune responses to the 13-valent pneumococcal conjugate vaccine (PCV13) given concomitantly with the combined DTaP/HBV/IPV/Hib vaccine. METHODS:Subjects receiv...

journal_title：Vaccine

authors： Wysocki J,Center KJ,Brzostek J,Majda-Stanislawska E,Szymanski H,Szenborn L,Czajka H,Hasiec B,Dziduch J,Jackowska T,Witor A,Kopińska E,Konior R,Giardina PC,Sundaraiyer V,Patterson S,Gruber WC,Scott DA,Gurtman A

更新日期：2017-04-04 00:00:00

abstract：:Peptides representing epitopes of the measles virus glycoproteins have been designed to induce neutralizing and protective antibodies. Those that escape recognition by passively acquired anti-whole virus antibodies could potentially be used as components of a 'pre-vaccine' that could be given during early childhood ir...

journal_title：Vaccine

authors： El Kasmi KC,Muller CP

更新日期：2001-03-21 00:00:00

abstract：:Respiratory syncytial virus (RSV) is the most common cause of serious acute lower respiratory illness in infants and young children and a significant cause of disease burden in the elderly and immunocompromised. There are no licensed RSV vaccines to address this significant public health need. While advances in vaccin...

journal_title：Vaccine

authors： Roberts JN,Graham BS,Karron RA,Munoz FM,Falsey AR,Anderson LJ,Marshall V,Kim S,Beeler JA

更新日期：2016-09-22 00:00:00

abstract：:A carcinoembryonic antigen (CEA)-based DNA vaccine, adsorbed onto cationic microparticles of poly(DL-lactide-co-glycolide) (PLG) induced tumor-protective immunity against a lethal challenge of MC38-CEA colon carcinoma cells in CEA-transgenic mice that was more potent than that of the corresponding naked DNA vaccine. B...

journal_title：Vaccine

authors： Luo Y,O'Hagan D,Zhou H,Singh M,Ulmer J,Reisfeld RA,James Primus F,Xiang R

更新日期：2003-05-16 00:00:00

abstract：:Intranasal (i.n.) immunization of BALB/c mice with chimeric murine rotavirus EDIM (epizootic diarrhea of infant mice) VP6 and attenuated E. coli heat-labile toxin (LT), LT(R192G), stimulated >99% protection against rotavirus shedding after EDIM challenge. Here, we evaluated other potential adjuvants with chimeric VP6 ...

journal_title：Vaccine

authors： Choi AH,McNeal MM,Flint JA,Basu M,Lycke NY,Clements JD,Bean JA,Davis HL,McCluskie MJ,VanCott JL,Ward RL

更新日期：2002-03-15 00:00:00

abstract：:Systemic infection by Salmonella typhimurium requires coordinated expression of virulence genes found primarily in Salmonella Pathogenecity Islands (SPIs). We have previously reported that the intracellular signal that induces these virulence genes is a stringent signal molecule, ppGpp [Song et al. J Biol Chem 2003;27...

journal_title：Vaccine

authors： Na HS,Kim HJ,Lee HC,Hong Y,Rhee JH,Choy HE

更新日期：2006-03-15 00:00:00

abstract：:A recombinant vector vaccine uses an attenuated virus, bacterium, or parasite as the carrier to express a heterologous antigen(s). Many recombinant vaccine vectors and related vaccines have been developed and extensively investigated. To compare and better understand recombinant vectors and vaccines, we have generated...

journal_title：Vaccine

authors： Deng S,Martin C,Patil R,Zhu F,Zhao B,Xiang Z,He Y

更新日期：2015-11-27 00:00:00