New strategies for closing the gap of measles susceptibility in infants: towards vaccines compatible with current vaccination schedules.

abstract：:Mathematical models provide valuable insights into the public health and economic impact of cervical cancer vaccination programmes. An in-depth economic analysis should explore the effects of different vaccine-related factors and vaccination scenarios (independent of screening practices) on health benefits and costs. ...

journal_title：Vaccine

authors： Suárez E,Smith JS,Bosch FX,Nieminen P,Chen CJ,Torvinen S,Demarteau N,Standaert B

更新日期：2008-09-15 00:00:00

abstract：:Plasmid DNA encoding herpes simplex virus type-1 glycoprotein D (gD-1) was complexed with asialoorosomucoid conjugated to poly-L-lysine. Following its intravenous injection into BALB/c mice, this complex was targeted to the liver. Liver cells expressing gD-1 were detected immunohistochemically through day 6 post-immun...

journal_title：Vaccine

authors： Rogers JV,Hull BE,Fink PS,Chiou HC,Bigley NJ

更新日期：2000-02-14 00:00:00

abstract：INTRODUCTION:In 2009, girls-only HPV16/18 vaccination was introduced in the Netherlands which has achieved 46-61% uptake. Heterosexual men have benefitted from herd protection, but it is unknown whether men who have sex with men (MSM) also benefit from herd effects of the girls-only HPV16/18 vaccination program. Becaus...

journal_title：Vaccine

authors： Woestenberg PJ,van Benthem BHB,Bogaards JA,King AJ,van der Klis FRM,Pasmans H,Leussink S,van der Sande MAB,Hoebe CJPA,Medical Microbiological Laboratories, the Public Health Services.

更新日期：2020-04-09 00:00:00

abstract：:Peptidoglycan monomer (PGM) is a natural compound of bacterial origin. It is a non-toxic, non-pyrogenic, water-soluble immunostimulator potentiating humoral immune response to ovalbumin (OVA) in mice. It is fast degraded and its metabolic products-the pentapeptide (PP) and the disaccharide (DS)-are excreted from the m...

journal_title：Vaccine

authors： Halassy B,Krstanović M,Frkanec R,Tomasić J

更新日期：2003-02-14 00:00:00

abstract：BACKGROUND:Typhoid fever remains a major public health problem in low- and middle-income countries where children aged 2-14 years bear the greatest burden. Vi polysaccharide is poorly immunogenic in children <2 years of age, and protection in adults is modest. The limitations of Vi polysaccharide vaccines can be overco...

journal_title：Vaccine

authors： Capeding MR,Teshome S,Saluja T,Syed KA,Kim DR,Park JY,Yang JS,Kim YH,Park J,Jo SK,Chon Y,Kothari S,Yang SY,Ham DS,Ryu JH,Hwang HS,Mun JH,Lynch JA,Kim JH,Kim H,Excler JL,Sahastrabuddhe S

更新日期：2018-06-18 00:00:00

abstract：INTRODUCTION:The Global Vaccine Action Plan identifies workforce capacity building as a key strategy to achieve strong immunization programs. The Strengthening Technical Assistance for Routine Immunization Training (START) approach aimed to utilize practical training methods to build capacity of district and health cen...

journal_title：Vaccine

authors： Ward K,Stewart S,Wardle M,Sodha SV,Tanifum P,Ayebazibwe N,Mayanja R,Luzze H,Ehlman DC,Conklin L,Abbruzzese M,Sandhu HS

更新日期：2019-05-09 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Public concern about an unsubstantiated link between MMR vaccine and autism stemmed from a 1998 paper by Dr Andrew Wakefield and colleagues, and the substantial media coverage which that work attracted. Though the Wakefield paper is now discredited and an MMR-autism link has never been demonst...

journal_title：Vaccine

authors： Brown KF,Long SJ,Ramsay M,Hudson MJ,Green J,Vincent CA,Kroll JS,Fraser G,Sevdalis N

更新日期：2012-02-27 00:00:00

abstract：:Despite extensive research, no unifying concept has satisfactorily explained the cause of the sudden infant death syndrome (SIDS). The details are briefly outlined of some of the evidence supporting the hypothesis that common bacterial toxins are important in the aetiology of SIDS. These bacterial toxins act as trigge...

journal_title：Vaccine

authors： Murrell TG,Murrell WG,Lindsay JA

更新日期：1994-03-01 00:00:00

abstract：:HIV-1 Tat protein activates resting cells, rendering them permissive for viral replication. Replication of HIV-1 in vitro is enhanced by intercellular passage of Tat protein and inhibited by anti-Tat antibodies. Tat dependence of HIV-1 replication in vivo during acute, chronic asymptomatic and AIDS stages of infection...

journal_title：Vaccine

authors： Goldstein G,Manson K,Tribbick G,Smith R

更新日期：2000-06-15 00:00:00

abstract：INTRODUCTION:Because of the long interval between infection with high-risk human papillomavirus (hrHPV) and development of cervical cancer surrogate markers for cancer incidence are necessary to monitor vaccine effectiveness (VE). The aim of this study was to calculate VE of HPV16/18 vaccination by annually assessing i...

journal_title：Vaccine

authors： Mollers M,King AJ,Knol MJ,Scherpenisse M,Meijer CJ,van der Klis FR,de Melker HE

更新日期：2015-05-28 00:00:00

abstract：BACKGROUND:Although guidelines for prophylactic human papillomavirus (HPV) vaccination recommend two doses for girls ages 9-14 years, several studies have demonstrated similar protection with one dose. Our objective was to evaluate the long-term health and economic impacts of routine one-dose HPV vaccination compared t...

journal_title：Vaccine

authors： Burger EA,Campos NG,Sy S,Regan C,Kim JJ

更新日期：2018-08-06 00:00:00

abstract：:Immune responses to poorly immunogenic antigens, such as polysaccharides, can be enhanced by conjugation to carriers. Our previous studies indicate that conjugation to Vi polysaccharide of Salmonella Typhi may also enhance immunogenicity of some protein carriers. We therefore explored the possibility of generating a b...

journal_title：Vaccine

authors： An SJ,Scaria PV,Chen B,Barnafo E,Muratova O,Anderson C,Lambert L,Chae MH,Yang JS,Duffy PE

更新日期：2018-05-17 00:00:00

abstract：:Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes acute encephalitis with high mortality in humans. To understand the virus-host interactions that influence JEV virulence, we determined the lethality of a neurovirulent (RP-9) and an attenuated (RP-2ms) variant of JEV in several immunodeficie...

journal_title：Vaccine

authors： Liang JJ,Liao CL,Liao JT,Lee YL,Lin YL

更新日期：2009-05-11 00:00:00

abstract：:The development of a safe and effective vaccine against enterotoxigenic Escherichia coli (ETEC) would be useful for travellers and for young children in endemic areas. A feasibility study of an enteral ETEC vaccine prototype consisting of colonization factor antigen II (CFA/II), containing two component antigens CS1 a...

journal_title：Vaccine

authors： Tacket CO,Reid RH,Boedeker EC,Losonsky G,Nataro JP,Bhagat H,Edelman R

更新日期：1994-11-01 00:00:00

abstract：:Immunogenicity of inactivated virus or subviral vaccines may be enhanced by complexing with an IgG antibody. Such antibody would increase the uptake, processing and presentation of the vaccine's antigens by antigen presenting cells (APC), via the adhesion of the antibody-vaccine complex to Fc-receptors on macrophages ...

journal_title：Vaccine

authors： Galili U,Repik PM,Anaraki F,Mozdzanowska K,Washko G,Gerhard W

更新日期：1996-03-01 00:00:00

abstract：:Infection with influenza virus during pregnancy poses a significant risk of complications for both mother and fetus. During the H1N1 2009 pandemic, pregnant women constituted one of the priority groups for vaccination in many countries, creating a need for close monitoring of the safety of the vaccine in pregnant wome...

journal_title：Vaccine

authors： Tavares F,Nazareth I,Monegal JS,Kolte I,Verstraeten T,Bauchau V

更新日期：2011-08-26 00:00:00

abstract：:Different subsets of dendritic cells (DC) elicit qualitatively different immune responses. In mice, two lymphoid tissue-resident subsets, CD8α(+) and CD8α(-), have been implicated in the induction of T helper 1 (Th1) or Th2 responses, respectively. Moreover, CD8α(+) DC appear to play a major role in priming CD8(+) T l...

journal_title：Vaccine

authors： Suleman M,Galea S,Gavard F,Merillon N,Klonjkowski B,Tartour E,Richardson J

更新日期：2011-08-11 00:00:00

abstract：:The anti-tumor immunologic effects of plasmid DNA vaccines encoding human carcinoembryonic antigen (CEA) fused to mouse granulocyte/macrophage colony-stimulating factor (GM-CSF) were examined. Immunization of C57BL/6 mice with the CEA-GMCSF fusion plasmids in a three injection, high-dose immunization schedule led to T...

journal_title：Vaccine

authors： Lima J,Jenkins C,Guerrero A,Triozzi PL,Shaw DR,Strong TV

更新日期：2005-01-26 00:00:00

abstract：:We assessed adult male and female awareness and acceptance of human papillomavirus (HPV) infection and vaccination for cervical cancer prevention, as well as factors associated with willingness to be administered the HPV vaccine. A nationwide population-based interview survey was conducted in Korea. One thousand male ...

journal_title：Vaccine

authors： Oh JK,Lim MK,Yun EH,Lee EH,Shin HR

更新日期：2010-02-17 00:00:00

abstract：:In a single-center study, 66 healthy volunteers aged between 18 and 50years were randomized to be immunized against rabies with three different injection routes: intradermal with DebioJect™ (IDJ), standard intradermal with classical needle (IDS), also called Mantoux method, and intramuscular with classical needle (IM)...

journal_title：Vaccine

authors： Vescovo P,Rettby N,Ramaniraka N,Liberman J,Hart K,Cachemaille A,Piveteau LD,Zanoni R,Bart PA,Pantaleo G

更新日期：2017-03-27 00:00:00

abstract：INTRODUCTION:One of the goals of the Global Measles and Rubella Strategic Plan is the reduction in global measles mortality, with high measles vaccination coverage as one of its core components. While measles mortality has been reduced more than 79%, the disease remains a major cause of childhood vaccine preventable di...

journal_title：Vaccine

authors： Doshi RH,Eckhoff P,Cheng A,Hoff NA,Mukadi P,Shidi C,Gerber S,Wemakoy EO,Muyembe-Tafum JJ,Kominski GF,Rimoin AW

更新日期：2017-10-27 00:00:00

abstract：:To prepare a human HBV vaccine, investigators need an animal model that can help them screen and prioritize vaccine candidates. In this study, HBV/HLA-A2.1 double transgenic mice (dTg), confirmed by analysis of genomic integration and by observation of long-term expression of HBV and HLA genes, were generated for the ...

journal_title：Vaccine

authors： Guo Y,Ren D,He X,Wang F,Jiang L,Song S,He Y,Sun S

更新日期：2009-09-18 00:00:00

abstract：BACKGROUND:The world's first dengue vaccine [Dengvaxia; Sanofi Pasteur] was licensed in 2015 and others are in development. Real-world evaluations of dengue vaccines will therefore soon be needed. We assessed feasibility of case control (CC) and test-negative (TN) design studies for dengue vaccine effectiveness by meas...

journal_title：Vaccine

authors： Nealon J,Lim WY,Moureau A,Linus Lojikip S,Junus S,Kumar S,Nachiappan JP,Devi Sekaran S,Radigue C,Cowling BJ,Ochiai RL,Hss AS

更新日期：2019-09-16 00:00:00

abstract：:DNA isolates from a number of established cell lines have been tested for their transforming capacity in the NIH3T3 transformation assay. It has been found that this assay can be used to quantify the amount of transforming DNA at a submicrogram to milligram level. This assay system has been applied to validate the red...

journal_title：Vaccine

authors： van Meel FC,Steenbakkers PG,Bos E

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:The development of a vaccine against the human gastric pathogen Helicobacter pylori, the main causative agent of gastric adenocarcinoma, has been hampered by a number of issues, including the lack of a mucosal adjuvant for use in humans. Heat shock proteins (Hsp), highly conserved molecules expressed by both...

journal_title：Vaccine

authors： Chionh YT,Arulmuruganar A,Venditti E,Ng GZ,Han JX,Entwisle C,Ang CS,Colaco CA,McNulty S,Sutton P

更新日期：2014-04-25 00:00:00

abstract：:A newly developed human diploid cell rabies vaccine (Lyssavac-HDC), produced without added serum albumin and with an effort to remove the virus-inactivating beta-propriolactone prior to addition of the gelatin, L-cysteine and potassium phosphate stabilizer, was tested for safety immunogenicity, adverse reactions and e...

journal_title：Vaccine

authors： Wilde H,Glueck R,Khawplod P,Cryz SJ,Tantawichien T,Thipkong P,Chomchey P,Prakongsri S,Benjavongkulchai M,Sumboonanondha A

更新日期：1995-04-01 00:00:00

abstract：:Oral poliovirus vaccine (OPV) is tested for safety by evaluation of neurovirulence in rhesus and cynomolgus macaques. After intraspinal or intrathalamic injection of varying doses of vaccine, monkeys are followed for 17-21 days, killed, and a histopathological evaluation is made of the severity of poliomyelitis lesion...

journal_title：Vaccine

authors： Nathanson N,Horn SD

更新日期：1992-01-01 00:00:00

abstract：:Trehalose-6,6'-dimycolate (TDM) and its monosaccharide-type analogues were synthesized, and their lethal and adjuvant activities were examined in mice. All the monosaccharide-type analogues with a glucose or N-acetylglucosamine moiety were devoid of lethal toxicity to mice; in particular, D-GlcNAcM(1-deoxy) and D-GlcN...

journal_title：Vaccine

authors： Sakurai T,Saiki I,Ishida H,Takeda K,Azuma I

更新日期：1989-06-01 00:00:00

abstract：:Life has its problems. To succeed it has to survive: to survive it has to sacrifice its identity. And viruses have their fingers in the essence of it all. Consider the situation. There are useful genes. Such genes promote the survival of the individuals which house them. It is not unreasonable, therefore, to expect th...

journal_title：Vaccine

authors： Spier RE

更新日期：1991-12-01 00:00:00

abstract：:The principle of deliberately infecting humans with infectious agents in a controlled setting, so-called controlled human infections (CHI), is not novel. Many CHI models have a long history and were established decades ago such as the intentional exposure to yellow fever and dengue performed in the 1900's (Reed, 1902)...

journal_title：Vaccine

authors： Roestenberg M,Mo A,Kremsner PG,Yazdanbakhsh M

更新日期：2017-12-18 00:00:00