Antigen dependent and independent mechanisms that sustain serum antibody levels.

abstract：:Langmuir adsorption isotherms of endotoxin and aluminum-containing adjuvants at pH 7.4 and 25 degrees C revealed that aluminum hydroxide adjuvant has a greater adsorption capacity (283 microg/mg Al) and adsorption coefficient (1.3x10(4) ml/miccrog) than aluminum phosphate adjuvant (3.0 microg/mg Al, 0.20 ml/microg). T...

journal_title：Vaccine

authors： Shi Y,HogenEsch H,Regnier FE,Hem SL

更新日期：2001-02-08 00:00:00

abstract：:Francisella tularensis is the intracellular bacterial pathogen causing the respiratory life-threatening disease tularemia. Development of tularemia vaccines has been hampered by an incomplete understanding of the correlates of immunity. Moreover, the importance of lung cellular immunity in vaccine-mediated protection ...

journal_title：Vaccine

authors： Bar-On L,Cohen H,Elia U,Rotem S,Bercovich-Kinori A,Bar-Haim E,Chitlaru T,Cohen O

更新日期：2017-12-15 00:00:00

abstract：:We created and produced a novel self-assembling nanoparticle platform for delivery of peptide epitopes that induces CD8(+) and CD4(+)T cells that are protective against Toxoplasma gondii infection. These self-assembling polypeptide nanoparticles (SAPNs) are composed of linear peptide (LP) monomers which contain two co...

journal_title：Vaccine

authors： El Bissati K,Zhou Y,Dasgupta D,Cobb D,Dubey JP,Burkhard P,Lanar DE,McLeod R

更新日期：2014-05-30 00:00:00

abstract：:Large areas of many developing countries have no grid electricity. This is a serious challenge that threatens the continuity of the vaccine cold chain. The main alternatives to electrically powered refrigerators available for many years--kerosene- and gas-driven refrigerators--are plagued by problems with gas supply i...

journal_title：Vaccine

authors： McCarney S,Robertson J,Arnaud J,Lorenson K,Lloyd J

更新日期：2013-12-09 00:00:00

abstract：:Active and passive immunotherapy targeting amyloid-β (Aβ) may be the most promising strategy to prevent or treat Alzheimer's disease (AD). Previously, immunization with the recombinant 6Aβ15-T antigen generated robust anti-Aβ serum antibodies that strongly recognized Aβ42 oligomers in different mice, markedly reduced ...

journal_title：Vaccine

authors： Wang HC,Yu YZ,Liu S,Zhao M,Xu Q

更新日期：2016-04-04 00:00:00

abstract：:Dengue is a major infectious disease that affects people living in tropical and subtropical regions around the world. The causative agents are dengue virus serotype 1, 2, 3, and 4 (DENV1, 2, 3, and 4). Developing a vaccine for dengue is a high priority for public health, but traditional methods have faced numerous obs...

journal_title：Vaccine

authors： Pang X,Guo Y,Zhou Y,Fu W,Gu X

更新日期：2014-06-24 00:00:00

abstract：INTRODUCTION:Hepatitis B is a major preventable cause of morbidity and mortality from chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. We aimed to evaluate the performance and outcomes of the Korean Perinatal Hepatitis B Prevention Programme (PHBPP) and to investigate the impact of the current post-exp...

journal_title：Vaccine

authors： Yang TU,Jung CW,Kim D,Park HA,Jee Y

更新日期：2020-07-22 00:00:00

abstract：:On 16-17 November 2011, the Initiative for Vaccine Research of the World Health Organization convened jointly with the Wellcome Trust the fifth meeting on 'Influenza vaccines that induce broad spectrum and long-lasting immune responses'. The goals of the meeting were to examine new influenza vaccine research developme...

journal_title：Vaccine

authors： Hughes B,Hayden F,Perikov Y,Hombach J,Tam JS

更新日期：2012-10-19 00:00:00

abstract：:Conflicting findings regarding the level of protection offered by seasonal influenza vaccination against pandemic influenza H1N1 have been reported. We performed a test-negative case control study using sentinel patients from general practices in Victoria to estimate seasonal influenza vaccine effectiveness against la...

journal_title：Vaccine

authors： Kelly HA,Grant KA,Fielding JE,Carville KS,Looker CO,Tran T,Jacoby P

更新日期：2011-08-26 00:00:00

abstract：:Despite a wide array of safe and effective vaccines in use globally, with major impacts on health worldwide, the WHO Strategic Advisory Group of Experts (SAGE) on Immunization has been repeatedly confronted with reports of hesitancy towards accepting specific vaccines or vaccination programmes. This paper summarizes t...

journal_title：Vaccine

authors： Schuster M,Eskola J,Duclos P,SAGE Working Group on Vaccine Hesitancy.

更新日期：2015-08-14 00:00:00

abstract：:During their sixth annual meeting held in Manila (Philippines), the Asian Rabies Expert Bureau (AREB) reviewed the implementation of programs for rabies prevention, control, and elimination in Asia. AREB members strongly support a "one health" approach for controlling rabies, combining increased public awareness, comm...

journal_title：Vaccine

authors： Dodet B,Asian Rabies Expert Bureau (AREB).

更新日期：2010-04-26 00:00:00

abstract：BACKGROUND:In 2017, measles elimination was verified in Bhutan, and the country appears to have sufficiently high vaccination coverage to achieve rubella elimination. However, a measles and rubella serosurvey was conducted to find if any hidden immunity gaps existed that could threaten Bhutan's elimination status. MET...

journal_title：Vaccine

authors： Wangchuk S,Nogareda F,Tshering N,Khandu L,Pelden S,Wannemuehler K,Wangdi S,Wangchuk U,Mulders M,Tamang T,Patel MK

更新日期：2019-10-08 00:00:00

abstract：:The study evaluated and compared the prevalence of anti-HBs and exposure to hepatitis B virus (HBV) in vaccinated South African babies aged between 5 and 24 months from the Expanded Programme on Immunisation clinic [EPI group] and paediatric outpatient clinic [OPD group], and results were stratified by HIV status. A t...

journal_title：Vaccine

authors： Simani OE,Leroux-Roels G,François G,Burnett RJ,Meheus A,Mphahlele MJ

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Few studies report the effectiveness of trivalent inactivated influenza vaccine (TIV) in preventing hospitalisation for influenza-confirmed respiratory infections. Using a prospective surveillance platform, this study reports the first such estimate from a well-defined ethnically diverse population in New Ze...

journal_title：Vaccine

authors： Turner N,Pierse N,Bissielo A,Huang QS,Baker MG,Widdowson MA,Kelly H,SHIVERS investigation team.

更新日期：2014-06-17 00:00:00

abstract：:sLAG-3 (IMP321), a natural high affinity ligand for MHC class II, was tested for safety, tolerability and its ability to increase Th-1-type T cell responses to a commercial trivalent split influenza vaccine (Agrippal) in a phase I single-blinded, randomized, controlled clinical trial. Twenty healthy volunteers were fi...

journal_title：Vaccine

authors： Brignone C,Grygar C,Marcu M,Perrin G,Triebel F

更新日期：2007-06-11 00:00:00

abstract：BACKGROUND:RTS,S/AS01 is a safe and moderately efficacious vaccine considered for implementation in endemic Africa. Model predictions of impact and cost-effectiveness of this new intervention could aid in country adoption decisions. METHODS:The impact of RTS,S was assessed in 43 countries using an ensemble of models o...

journal_title：Vaccine

authors： Galactionova K,Tediosi F,Camponovo F,Smith TA,Gething PW,Penny MA

更新日期：2017-01-03 00:00:00

abstract：OBJECTIVE:To compare timely birth dose (TBD) coverage of hepatitis B vaccine and socio-economic inequality distribution of TBD coverage between 2011 and 2016 in rural areas of western China. METHODS:In western China, using multi-stage probability proportion to size sampling, 2633 and 1929 children aged 0-35 months wit...

journal_title：Vaccine

authors： Liu X,Yang C,Zhong Q,Song Q,Huang X,Yang Y,Huang Y,Wang Y,Zhou H

更新日期：2018-06-22 00:00:00

abstract：:We report the development of a novel protein-based nasal vaccine against Streptococcus pneumoniae, in which three pneumococcal proteins were displayed on the surface of a non-recombinant, killed Lactococcus lactis-derived delivery system, called Gram-positive Enhancer Matrix (GEM). The GEM particles induced the produc...

journal_title：Vaccine

authors： Audouy SA,van Selm S,van Roosmalen ML,Post E,Kanninga R,Neef J,Estevão S,Nieuwenhuis EE,Adrian PV,Leenhouts K,Hermans PW

更新日期：2007-03-22 00:00:00

abstract：:An experimental infection with classical swine fever (CSF) virus in E2 sub-unit marker vaccine vaccinated gilts was conducted in order to evaluate the effect of vaccination on virus transmission and course of the disease. Therefore, clinical signs as well as horizontal and vertical virus transmission were monitored in...

journal_title：Vaccine

authors： Dewulf J,Laevens H,Koenen F,Mintiens K,de Kruif A

更新日期：2001-10-12 00:00:00

abstract：:Strains of Newcastle disease virus (NDV) can be separated into genotypes based on genome differences even though they are antigenically considered to be of a single serotype. It is widely recognized that an efficacious Newcastle disease (ND) vaccine made with any NDV does induce protection against morbidity and mortal...

journal_title：Vaccine

authors： Miller PJ,King DJ,Afonso CL,Suarez DL

更新日期：2007-10-10 00:00:00

abstract：:Haemophilus parasuis (H. parasuis) is a swine pathogen responsible for the Glässer's disease, which has received more attention in the past decade due to the increasing economic losses in the pig industry worldwide. As traditional inactive vaccine of H. parasuis has obvious disadvantage, to identify efficient immunopr...

journal_title：Vaccine

authors： Li M,Song S,Yang D,Li C,Li G

更新日期：2015-03-30 00:00:00

abstract：INTRODUCTION:Pan American Health Organization's (PAHO) ProVac Initiative aims to strengthen countries' technical capacity to make evidence-based immunization policy. With financial support from the Bill and Melinda Gates Foundation, PAHO established the ProVac International Working Group (IWG), a platform created for t...

journal_title：Vaccine

authors： Jauregui B,Garcia AG,Bess Janusz C,Blau J,Munier A,Atherly D,Mvundura M,Hajjeh R,Lopman B,Clark AD,Baxter L,Hutubessy R,de Quadros C,Andrus JK

更新日期：2015-05-07 00:00:00

abstract：:In a 12-month cohort follow-up study of 2435 children vaccinated in 2007 by Statens Serum Institute BCG strain (BCG SSI, 17.8% had an adverse event (AE): erythema 12.4%, induration 12.2%, abscesses 2.5%, ulceration 0.9%, lymphadenitis 0.1%. The factors associated with a lower risk of AE were: age at vaccination <1 yea...

journal_title：Vaccine

authors： Dommergues MA,de La Rocque F,Guy C,Lécuyer A,Jacquet A,Guérin N,Fagot JP,Boucherat M,d'Athis P,Cohen R

更新日期：2009-11-23 00:00:00

abstract：:Peptides representing epitopes of the measles virus glycoproteins have been designed to induce neutralizing and protective antibodies. Those that escape recognition by passively acquired anti-whole virus antibodies could potentially be used as components of a 'pre-vaccine' that could be given during early childhood ir...

journal_title：Vaccine

authors： El Kasmi KC,Muller CP

更新日期：2001-03-21 00:00:00

abstract：BACKGROUND:In most low and middle-income countries (LMIC), vaccines are primarily distributed by routine immunization services (RI) at health facilities. Additional opportunities for vaccination are also provided through mass vaccination campaigns, conducted periodically as part of disease-specific initiatives. It is u...

journal_title：Vaccine

authors： Helleringer S,Asuming PO,Abdelwahab J

更新日期：2016-07-19 00:00:00

abstract：:ErbB-2 is associated with several solid tumours of which breast cancer is the commonest cancer in women worldwide. Though anti-ErbB-2 antibody appears to play a significant role in prevention and therapy, naturally occurring anti-ErbB-2 antibody associated with the cleaved ectodomain of overexpressed ErbB-2 self antig...

journal_title：Vaccine

authors： Mukhopadhyay A,Dyring C,Stott DI

更新日期：2014-02-12 00:00:00

abstract：BACKGROUND:Alternative methods for influenza vaccine production are needed to ensure adequate supplies. METHODS:Healthy adults 50-64 years were assigned randomly to receive one intramuscular injection of trivalent recombinant hemagglutinin (rHA) or U.S. licensed trivalent inactivated vaccine (TIV) containing H1, H3 an...

journal_title：Vaccine

authors： Baxter R,Patriarca PA,Ensor K,Izikson R,Goldenthal KL,Cox MM

更新日期：2011-03-09 00:00:00

abstract：:Seneca Valley virus (SVV) infection in pigs is associated with porcine idiopathic vesicular disease (PIVD). Outbreaks of SVV infection in pig herds have been reported in several Asia and Americas countries. Recently, a series of outbreaks of SVV infection occurred in China, Canada, Thailand and the United States. Howe...

journal_title：Vaccine

authors： Yang F,Zhu Z,Cao W,Liu H,Zhang K,Tian H,Liu X,Zheng H

更新日期：2018-02-01 00:00:00

abstract：:This study investigated predictors of influenza vaccination uptake since the introduction of the policy to target over 65s. Four hundred and forty-four participants completed a cross-sectional structured interview. The predictors of vaccination uptake were: having a doctor or nurse who explained why the vaccination is...

journal_title：Vaccine

authors： Burns VE,Ring C,Carroll D

更新日期：2005-05-20 00:00:00

abstract：:Uncertainty regarding the benefits of influenza vaccination may contribute to the underutilization of this vaccine. We have conducted serial cohort studies using the administrative data bases of a Twin Cities based managed care organization to assess the impact of disease and benefits of vaccination among the elderly....

journal_title：Vaccine

authors： Nichol KL

更新日期：1999-07-30 00:00:00