Bacillus spores for vaccine delivery.

Abstract:

:Spores of the genus Bacillus have been used for a long time as probiotics for oral bacteriotherapy both in humans and in animals. Spores are also employed in a veterinary vaccine against anthrax. Despite this long lasting and extensive use, the specific contribution of spores to the beneficial effects of probiotics and to the immunogenicity of the vaccine is not completely elucidated. This review focuses on the different aspects of the use of spore preparations. In particular the use of recombinant spores as vaccine delivery vehicles is described and discussed.

journal_name

Vaccine

journal_title

Vaccine

authors

Oggioni MR,Ciabattini A,Cuppone AM,Pozzi G

doi

10.1016/s0264-410x(03)00207-x

subject

Has Abstract

pub_date

2003-06-01 00:00:00

pages

S96-101

eissn

0264-410X

issn

1873-2518

pii

S0264410X0300207X

journal_volume

21 Suppl 2

pub_type

杂志文章,评审

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