Abstract:
:Spores of the genus Bacillus have been used for a long time as probiotics for oral bacteriotherapy both in humans and in animals. Spores are also employed in a veterinary vaccine against anthrax. Despite this long lasting and extensive use, the specific contribution of spores to the beneficial effects of probiotics and to the immunogenicity of the vaccine is not completely elucidated. This review focuses on the different aspects of the use of spore preparations. In particular the use of recombinant spores as vaccine delivery vehicles is described and discussed.
journal_name
Vaccinejournal_title
Vaccineauthors
Oggioni MR,Ciabattini A,Cuppone AM,Pozzi Gdoi
10.1016/s0264-410x(03)00207-xsubject
Has Abstractpub_date
2003-06-01 00:00:00pages
S96-101eissn
0264-410Xissn
1873-2518pii
S0264410X0300207Xjournal_volume
21 Suppl 2pub_type
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