Efficacy of DNA-hsp65 vaccination for tuberculosis varies with method of DNA introduction in vivo.

abstract：:A family of parasite antigens known as Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is believed to play an important role in the binding of infected erythrocytes to host receptors in the micro-vasculature. Available data advocates the existence of a subset of very adhesive (rosetting, auto-agglutinati...

journal_title：Vaccine

authors： Chen Q,Pettersson F,Vogt AM,Schmidt B,Ahuja S,Liljeström P,Wahlgren M

更新日期：2004-07-29 00:00:00

abstract：:HIV infection is characterized by chronic immune activation and the establishment of a pool of latently infected cells. Antiretroviral therapy (ART) can suppress viral load to undetectable levels in peripheral blood by standard measure, however immune activation/chronic inflammation and latent infection persist and af...

journal_title：Vaccine

authors： Pallikkuth S,Bolivar H,Fletcher MA,Babic DZ,De Armas LR,Gupta S,Termini JM,Arheart KL,Stevenson M,Tung FY,Fischl MA,Pahwa S,Stone GW

更新日期：2020-06-02 00:00:00

abstract：:This cross-sectional study aimed to assess pertussis seroprevalence among healthy healthcare workers (HCW) of the Children's Hospital of Tunis, Tunisia. During the study period, 236 blood samples were obtained to determine HCW exposure to pertussis. Concentrations of immunoglobulin G (IgG) to pertussis toxin (PT) were...

journal_title：Vaccine

authors： Ben Fraj I,Smaoui H,Zghal M,Sassi O,Guiso N,Kechrid A

更新日期：2019-01-03 00:00:00

abstract：:The objectives of this study were to evaluate the effects of a therapeutic vaccine intervention with a modified-live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine on the dynamics of a heterologous viral infection in a population of pigs, and to determine the clinical and virological response of p...

journal_title：Vaccine

authors： Cano JP,Dee SA,Murtaugh MP,Pijoan C

更新日期：2007-05-30 00:00:00

abstract：:Rabies virus remains an important burden of disease claiming an estimated 60,000 lives each year, mainly children, and having a huge economical and societal cost. Post-exposure prophylaxis (PEP) is highly effective, however in patients that present with neurological symptoms the case-fatality ratio is extremely high (...

journal_title：Vaccine

authors： Jochmans D,Neyts J

更新日期：2019-08-02 00:00:00

abstract：:To improve immune responses to influenza vaccine, a trivalent inactivated vaccine containing 60 microg of the HA of each component (A/H3N2, A/H1N1, B) was compared to a licensed vaccine containing 15 microg of the HA of each. More local and systemic reactions were reported by subjects given the high dosage but only lo...

journal_title：Vaccine

authors： Couch RB,Winokur P,Brady R,Belshe R,Chen WH,Cate TR,Sigurdardottir B,Hoeper A,Graham IL,Edelman R,He F,Nino D,Capellan J,Ruben FL

更新日期：2007-11-01 00:00:00

abstract：:Inactivated influenza vaccine is recommended for routine use in high-risk individuals in the United States, including women who will be in the second or third trimesters of pregnancy. The basis for this recommendation is the high risk of exposure and disease due to influenza viruses in pregnant women, as well as the i...

journal_title：Vaccine

authors： Englund JA

更新日期：2003-07-28 00:00:00

abstract：:Patients with malignancies are considered to be at increased risk of acquiring influenza. Because of higher complication and case fatality rates, preventive measures such as vaccination are of great interest. The objective of this study was to assess the acceptability, tolerability and immunogenicity of an adjuvant-fr...

journal_title：Vaccine

authors： Lagler H,Tobudic S,Ramharter M,Elandt K,Sperr WR,Redlberger-Fritz M,Popow-Kraupp T,Jäger U,Zielinski CC,Burgmann H

更新日期：2012-11-06 00:00:00

abstract：OBJECTIVE:To systematically review literature on uptake and timeliness of diphtheria-tetanus-pertussis, measles-mumps-rubella, and/or polio-containing vaccines ininfants who were born preterm, with a low birth weight, and/or with chronic health conditions that were diagnosed within the first 6 months of life. METHODS:...

journal_title：Vaccine

authors： Walker EJ,MacDonald NE,Islam N,Le Saux N,Top KA,Fell DB

更新日期：2019-03-22 00:00:00

abstract：:C57BL/6 (B6) mice were immunized with a highly antigenic 10-mer peptide (P12-10), which is encoded by the murine AIDS (MAIDS) defective virus gag p12 gene, emulsified in incomplete Freund's adjuvant (ICFA). One week later, the mice were inoculated with the MAIDS virus to see if the immunization affects progression of ...

journal_title：Vaccine

authors： Mizuochi T,Horino A,Uchida T

更新日期：1998-12-01 00:00:00

abstract：:Potential vaccine strategies against otitis media are to prevent (1) symptomatic infections in the middle ear and/or (2) carriage of pneumococci and thereby subsequent middle ear infections. The possibility of using immunity to virulence proteins of pneumococci to elicit immunity against pneumococci has been examined....

journal_title：Vaccine

authors： Briles DE,Hollingshead SK,Nabors GS,Paton JC,Brooks-Walter A

更新日期：2000-12-08 00:00:00

abstract：:Pfs25, a Plasmodium falciparum surface protein expressed during zygote and ookinete stages in infected mosquitoes, is a lead transmission-blocking vaccine candidate against falciparum malaria. To enhance immunogenicity, recombinant Pfs25 was chemically conjugated to recombinant nontoxic Pseudomonas aeruginosa ExoProte...

journal_title：Vaccine

authors： Zhu D,Wu Y,McClellan H,Dai W,Rausch K,Jones D,Aebig J,Barnafo E,Butler B,Lambert L,Narum DL,Duffy PE

更新日期：2017-05-31 00:00:00

abstract：INTRODUCTION:Endemic measles persists in China, despite >95% reported coverage of two measles-containing vaccine doses and nationwide campaign that vaccinated more than 100 million children in 2010. In 2011, almost half of the 9943 measles cases in China occurred in children eligible for measles vaccination. We conduct...

journal_title：Vaccine

authors： Hao L,Ma C,Wannemuehler KA,Su Q,An Z,Cairns L,Quick L,Rodewald L,Liu Y,He H,Xu Q,Ma Y,Yu W,Zhang N,Li L,Wang N,Luo H,Wang H,Gregory CJ

更新日期：2016-12-12 00:00:00

abstract：:Immune responses to the infectious bronchitis virus (IBV) nucleocapsid protein were studied using a recombinant-DNA expression product. In mice, a lymphocyte proliferative response and a delayed-type hypersensitivity reaction to IBV were induced upon immunization with this nucleocapsid protein. Next, we studied the ro...

journal_title：Vaccine

authors： Boots AM,Benaissa-Trouw BJ,Hesselink W,Rijke E,Schrier C,Hensen EJ

更新日期：1992-01-01 00:00:00

abstract：:In this study, a recombinant truncated West Nile virus envelope protein antigen (rWNV-E) was produced in serum-free cultures of the expresSF+ insect cell line via baculovirus infection. This production system was selected based on its use in the production of candidate human and animal vaccine antigens. A defined ferm...

journal_title：Vaccine

authors： Bonafé N,Rininger JA,Chubet RG,Foellmer HG,Fader S,Anderson JF,Bushmich SL,Anthony K,Ledizet M,Fikrig E,Koski RA,Kaplan P

更新日期：2009-01-07 00:00:00

abstract：:The immunological enhancement characteristics of the immunopotentiator CVC1302 were evaluated for foot-and-mouth disease virus (FMDV) inactivated vaccine in pigs. Eight-week-old piglets were vaccinated with the foot-and-mouth disease (FMD) vaccine alone (FMD-vaccine group) or with the addition of CVC1302 (FMD-CVC1302 ...

journal_title：Vaccine

authors： Chen J,Yu X,Zheng Q,Hou L,Du L,Zhang Y,Qiao X,Hou J,Huang K

更新日期：2018-12-18 00:00:00

abstract：:In the last quarter of the year 2000, the meningococcal C conjugated vaccine was incorporated into the routine vaccination schedule in Catalonia (at 2, 4 and 6 months). In addition a vaccination campaign was carried out in children <6 years of age, with a coverage of 96.2%. The effectiveness of the vaccination in this...

journal_title：Vaccine

authors： Salleras L,Domínguez A,Cardeñosa N

更新日期：2003-01-30 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated a correlation between Clostridium difficile anti-toxin A serum antibodies and protection against symptomatic disease and recurrence. METHODS:A neutralizing monoclonal antibody to C. difficile toxin A (CDA1) developed by MBL and Medarex, Inc. was studied in a phase II, rand...

journal_title：Vaccine

authors： Leav BA,Blair B,Leney M,Knauber M,Reilly C,Lowy I,Gerding DN,Kelly CP,Katchar K,Baxter R,Ambrosino D,Molrine D

更新日期：2010-01-22 00:00:00

abstract：:Current infant vaccination against pertussis in North America and Australia requires three doses of vaccines including diphtheria, tetanus and acellular pertussis antigens (DTaP) at 2, 4 and 6 months of age. Interest is growing in the possibility that vaccination at birth might provide earlier protection of infants, b...

journal_title：Vaccine

authors： White OJ,Rowe J,Richmond P,Marshall H,McIntyre P,Wood N,Holt PG

更新日期：2010-03-19 00:00:00

abstract：:Orally delivered replicating adenovirus (Ad) vaccines have been used for decades to prevent adenovirus serotype 4 and 7 respiratory illness in military recruits, demonstrating exemplary safety and high efficacy. That experience suggests that oral administration of live recombinant Ads (rAds) holds promise for immuniza...

journal_title：Vaccine

authors： Deal C,Pekosz A,Ketner G

更新日期：2013-07-11 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) vaccines have been recommended as primary prevention of HPV-related cancers for over 10 years in the United States, and evidence reveals decreased incidence of HPV infections following vaccination. However, concerns have been raised that HPV vaccines could decrease fertility. This ...

journal_title：Vaccine

authors： Schmuhl NB,Mooney KE,Zhang X,Cooney LG,Conway JH,LoConte NK

更新日期：2020-05-19 00:00:00

abstract：:Varied doses of Taishan Pinus massoniana pollen polysaccharide (TPPPS) and Astragalus polysaccharide (APS) extracted by hot water extraction and ethanol precipitation method were added to the vaccine in order to prepare polysaccharide-rabbit haemorrhagic disease (RHD) tissue inactivated vaccine. The purpose was to stu...

journal_title：Vaccine

authors： Wei K,Sun Z,Yan Z,Tan Y,Wang H,Zhu X,Wang X,Sheng P,Zhu R

更新日期：2011-03-21 00:00:00

abstract：INTRODUCTION:The Global Vaccine Action Plan identifies workforce capacity building as a key strategy to achieve strong immunization programs. The Strengthening Technical Assistance for Routine Immunization Training (START) approach aimed to utilize practical training methods to build capacity of district and health cen...

journal_title：Vaccine

authors： Ward K,Stewart S,Wardle M,Sodha SV,Tanifum P,Ayebazibwe N,Mayanja R,Luzze H,Ehlman DC,Conklin L,Abbruzzese M,Sandhu HS

更新日期：2019-05-09 00:00:00

abstract：:Interaction of native proteinaceous antigens during the recognition and the effector phases of an immune response leads to antigenic conformational modifications which may elicit additional specific immune response. Protein cross-linking and conformation restraining formaldehyde and glutaraldehyde have been extensivel...

journal_title：Vaccine

authors： Cepica A,Beauregard M,Qian B

更新日期：1998-12-01 00:00:00

abstract：:Successful vaccination of mice against an otherwise lethal challenge with the Peru strain of Trypanosoma cruzi necessitates the induction of a strong cell mediated immune response. Previously, immunization of mice with the paraflagellar rod proteins from Trypanosoma cruzi90% reduction in parasitemia in immunized mice ...

journal_title：Vaccine

authors： Wrightsman RA,Manning JE

更新日期：2000-01-31 00:00:00

abstract：BACKGROUND:There is a demand of affordable IPV in the World. Statens Serum Institut (SSI) has developed three reduced dose IPV formulations adsorbed to aluminium hydroxide; 1/3 IPV-Al, 1/5 IPV-Al and 1/10 IPV-Al SSI, and now report the results of the first investigations in humans. METHODS:240 Danish adolescents, aged...

journal_title：Vaccine

authors： Lindgren LM,Tingskov PN,Justesen AH,Nedergaard BS,Olsen KJ,Andreasen LV,Kromann I,Sørensen C,Dietrich J,Thierry-Carstensen B

更新日期：2017-01-23 00:00:00

abstract：:As a step in the development of an oral vaccine against ETEC, we evaluated the safety and immunogenicity of CS6, a polymeric protein commonly found on the surface of ETEC. Formulations included 1 and 5mg doses of CS6, either encapsulated in biodegradable polymer poly(D, L)-lactide-co-glycolide (PLG), or as free protei...

journal_title：Vaccine

authors： Katz DE,DeLorimier AJ,Wolf MK,Hall ER,Cassels FJ,van Hamont JE,Newcomer RL,Davachi MA,Taylor DN,McQueen CE

更新日期：2003-01-17 00:00:00

abstract：PURPOSE:Meningococcal C conjugate vaccine was included in December 2000 in the Spanish childhood vaccination at 2, 4 and 6 months of age. In 2006, routine vaccination was modified to two doses at 2 and 4-6 months and a booster dose during the second year of age. Additionally, successive catch-up campaigns were launched...

journal_title：Vaccine

authors： Garrido-Estepa M,León-Gómez I,Herruzo R,Cano R

更新日期：2014-05-07 00:00:00

abstract：:We investigated whether a combined DNA vaccine delivered together with the IL-15 gene (DNA-IL-15(+)) enhanced the immune response against Brucella abortus in mice. Mice vaccinated with DNA-IL-15(+) developed a robust humoral response; Brucella-specific antibodies exhibited a dominance of immunoglobulin G2a (IgG2a) ove...

journal_title：Vaccine

authors： Hu XD,Chen ST,Li JY,Yu DH,Yi-Zhang,Cai H

更新日期：2010-03-11 00:00:00

abstract：:After the publication of case reports of hepatitis B vaccinees with onset or relapse of multiple sclerosis (MS), followed by a media-driven scare campaign in France, the perception that hepatitis B vaccine causes MS has developed. This has led to a fall in the acceptance of hepatitis B vaccination particularly in Fren...

journal_title：Vaccine

authors： Monteyne P,André FE

更新日期：2000-04-03 00:00:00