Decreasing invasive pneumococcal disease in the elderly: a state-level analysis.

Abstract:

:Evidence has accumulated supporting the relationship between the use of 7-valent pneumococcal conjugate vaccine (PCV7) in children and a decline in invasive pneumococcal disease (IPD) in the elderly. We conducted a state-level analysis of vaccination coverage rates among children 19-35 months of age and IPD hospitalization rates among elderly Medicare beneficiaries. Simple correlations were suggestive of a negative relationship. Multivariate analysis using a state fixed-effect model which helped control for the time invariant factors at the state level also indicated a negative relationship, and it was statistically significant, p = 0.035. The relationship between the use of 23-valent pneumococcal polysaccharide vaccine (PPV23) and IPD hospitalizations was not statistically significant using either method.

journal_name

Vaccine

journal_title

Vaccine

authors

McBean AM,Jung K,Hebert PL

doi

10.1016/j.vaccine.2006.04.055

subject

Has Abstract

pub_date

2006-07-07 00:00:00

pages

5609-14

issue

27-28

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(06)00458-0

journal_volume

24

pub_type

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