Abstract：
:Evidence has accumulated supporting the relationship between the use of 7-valent pneumococcal conjugate vaccine (PCV7) in children and a decline in invasive pneumococcal disease (IPD) in the elderly. We conducted a state-level analysis of vaccination coverage rates among children 19-35 months of age and IPD hospitalization rates among elderly Medicare beneficiaries. Simple correlations were suggestive of a negative relationship. Multivariate analysis using a state fixed-effect model which helped control for the time invariant factors at the state level also indicated a negative relationship, and it was statistically significant, p = 0.035. The relationship between the use of 23-valent pneumococcal polysaccharide vaccine (PPV23) and IPD hospitalizations was not statistically significant using either method.
journal_name
Vaccinejournal_title
Vaccineauthors
McBean AM,Jung K,Hebert PLdoi
10.1016/j.vaccine.2006.04.055subject
Has Abstractpub_date
2006-07-07 00:00:00pages
5609-14issue
27-28eissn
0264-410Xissn
1873-2518pii
S0264-410X(06)00458-0journal_volume
24pub_type
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