Prophylaxis of experimental HTLV-I infection in cynomolgus monkeys by passive immunization.

Abstract:

:The protective effect of purified human immunoglobulin against human T-cell leukaemia virus type I (HTLV-I), designated ATLIG on HTLV-I infection was examined in cynomolgus monkeys (Macaca fascicularis) as a preclinical study. Passive immunization of ATLIG 24 h before challenging HTLV-I protected the monkeys from HTLV-I infection. The result suggests that passive immunization of ATLIG could provide safe and sufficient protection against HTLV-I infection in humans.

journal_name

Vaccine

journal_title

Vaccine

authors

Akari H,Suzuki T,Ikeda K,Hoshino H,Tomono T,Murotsuka T,Terao K,Ito H,Yoshikawa Y

doi

10.1016/s0264-410x(97)00055-8

subject

Has Abstract

pub_date

1997-08-01 00:00:00

pages

1391-5

issue

12-13

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(97)00055-8

journal_volume

15

pub_type

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