Abstract:
:The protective effect of purified human immunoglobulin against human T-cell leukaemia virus type I (HTLV-I), designated ATLIG on HTLV-I infection was examined in cynomolgus monkeys (Macaca fascicularis) as a preclinical study. Passive immunization of ATLIG 24 h before challenging HTLV-I protected the monkeys from HTLV-I infection. The result suggests that passive immunization of ATLIG could provide safe and sufficient protection against HTLV-I infection in humans.
journal_name
Vaccinejournal_title
Vaccineauthors
Akari H,Suzuki T,Ikeda K,Hoshino H,Tomono T,Murotsuka T,Terao K,Ito H,Yoshikawa Ydoi
10.1016/s0264-410x(97)00055-8subject
Has Abstractpub_date
1997-08-01 00:00:00pages
1391-5issue
12-13eissn
0264-410Xissn
1873-2518pii
S0264-410X(97)00055-8journal_volume
15pub_type
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