Extensively keratinized squamous intraepithelial lesions of the cervix are difficult to grade.

abstract：:A 28-month-old girl, whose parents are first cousins, was hospitalized following a series of severe infections. Results of functional granulocytic tests permitted the diagnosis of chronic granulomatous disease (lack of nitroblue tetrazolium dye reduction, impaired bactericidal activity for Staphylococcus aureus but no...

journal_title：American journal of clinical pathology

authors： Corberand J,De Larrard B,Vergnes H,Carrière JP

更新日期：1978-08-01 00:00:00

abstract：:Three brands of blood collection tubes were studied for their influence on the prothrombin time (PT) and international sensitivity index (ISI) for 5 commercial thromboplastin reagents. With all reagents, PTs were shorter in Vacutainer (Becton Dickinson Vacutainer Systems, Plymouth, England) samples than in S-Monovette...

journal_title：American journal of clinical pathology

authors： van den Besselaar AM,Hoekstra MM,Witteveen E,Didden JH,van der Meer FJ

更新日期：2007-05-01 00:00:00

abstract：:The effect of changes in cytology laboratory costs, including the costs of new technologies, on the cost-effectiveness of cervical cancer prevention has not been studied. Using University of Iowa laboratory detection rates and costs, a decision model determined the cost-effectiveness of the laboratory with and without...

journal_title：American journal of clinical pathology

authors： Raab SS,Zaleski MS,Silverman JF

更新日期：1999-02-01 00:00:00

abstract：:Hepatocytes with orcein-positive ground-glass cytoplasm have been shown to contain abundant hepatitis B surface antigen in the cisternae of excess smooth endoplasmic reticulum. Hepatocytes with similar cytoplasmic changes that did not react with orcein were observed in 26.5% of 49 cases of cirrhosis. These cells exhib...

journal_title：American journal of clinical pathology

authors： Gerber MA,Thung SN

更新日期：1981-04-01 00:00:00

abstract：:Prostate-specific antigen (PSA) is a sensitive and specific serum marker for monitoring disease activity in men with prostatic carcinoma. Despite reports of elevation of levels of this analyte in men with benign prostatic hyperplasia, no information is available correlating the serum levels with the actual prostatic a...

journal_title：American journal of clinical pathology

authors： Brawer MK,Rennels MA,Nagle RB,Schifman R,Gaines JA

更新日期：1989-12-01 00:00:00

abstract：OBJECTIVES:Cytogenetics defines disease entities and predicts prognosis in acute myeloid leukemia (AML). Conventional karyotyping provides a comprehensive view of the genome, while fluorescence in situ hybridization (FISH) detects targeted abnormalities. The aim of this study was to compare the utility of karyotyping a...

journal_title：American journal of clinical pathology

authors： He R,Wiktor AE,Hanson CA,Ketterling RP,Kurtin PJ,Van Dyke DL,Litzow MR,Howard MT,Reichard KK

更新日期：2015-06-01 00:00:00

abstract：:We studied methylation of 2 tumor suppressor genes (p14, p16) and 4 MINT (methylated in tumor) clones (MINT1, MINT2, MINT25, MINT31) among 51 fundic gland polyps (FGPs) and 27 normal gastric body biopsy samples using bisulfite treatment of genomic DNA followed by methylation-specific polymerase chain reaction. Thirty-...

journal_title：American journal of clinical pathology

authors： Abraham SC,Park SJ,Cruz-Correa M,Houlihan PS,Half EE,Lynch PM,Wu TT

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVES:Pool testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) preserves testing resources at the risk of missing specimens through specimen dilution. METHODS:To determine whether SARS-CoV-2 specimens would be missed after 10:1 pooling, we identified 10 specimens with midrange (ie, 25-34 cycl...

journal_title：American journal of clinical pathology

authors： Procop GW,Tuohy M,Ramsey C,Rhoads DD,Rubin BP,Figler R

更新日期：2021-01-05 00:00:00

abstract：:Clq precipitins were assayed in a model system by absorption nephelometry. Polyethylene glycol was used to extract immune complexes so that sufficient sensitivity with minimal interference could be achieved. Using a double beam spectrophotometer, we found that the reaction of immune complexes with Clq occurred rapidly...

journal_title：American journal of clinical pathology

authors： Levinson SS,Goldman J

更新日期：1983-04-01 00:00:00

abstract：:Several adulterants are used to mask tests for abused drugs in urine. Adulterants such as "Klear" and "Whizzies" contain potassium nitrite, and "Urine Luck" contains pyridinium chlorochromate (PCC). The presence of these adulterants cannot be detected by routine specimen integrity checks (pH, specific gravity, and tem...

journal_title：American journal of clinical pathology

authors： Dasgupta A,Wahed A,Wells A

更新日期：2002-02-01 00:00:00

abstract：:Bleeding problems are symptomatic of platelet delta-storage pool diseases (SPDs) such as Hermansky-Pudlak syndrome. Although at present no cure is available for delta-SPD, early diagnosis is of great importance for prophylactic and supportive treatment. This study tested the usefulness of a flow cytometric assay for p...

journal_title：American journal of clinical pathology

authors： Maurer-Spurej E,Pittendreigh C,Wu JK

更新日期：2007-04-01 00:00:00

abstract：:This is a report of an adenocarcinoma of mesonephric origin studied by light microscopy, electron microscopy, and immunocytochemistry. Unlike previous reports, our lesion was located paravaginally and not in the leaves of the broad ligament or in the cervix. The light microscopic features are similar to those of previ...

journal_title：American journal of clinical pathology

authors： Hinchey WW,Silva EG,Guarda LA,Ordonez NG,Wharton JT

更新日期：1983-10-01 00:00:00

abstract：Objectives:To evaluate the prognostic values of microRNAs (miRNAs) in glioblastoma, and to see if there is an association between miRNAs and MGMT promoter methylation status. Methods:We collected paraffin blocks from resection specimens from 114 glioblastoma patients who had received temozolomide treatment and radioth...

journal_title：American journal of clinical pathology

authors： Chen YY,Ho HL,Lin SC,Ho TD,Hsu CY

更新日期：2018-03-29 00:00:00

abstract：OBJECTIVES:To investigate metastasis associated in colon cancer 1 (MACC1) and MET expression in colorectal adenoma, Tis, early-stage invasive (T1 and T2), and advanced adenocarcinoma with liver metastasis using immunohistochemistry. METHODS:Ninety-three paraffin-embedded colorectal tumor specimens were immunohistochem...

journal_title：American journal of clinical pathology

authors： Ren B,Zakharov V,Yang Q,McMahon L,Yu J,Cao W

更新日期：2013-11-01 00:00:00

abstract：:The performance of the Coulter STKS (Coulter, Hialeah, FL) was evaluated in a busy computerized teaching hospital laboratory. The STKS was compared with a Coulter S Plus IV and manually performed 400 white blood-cell differentials. The measured blood-count parameters (i.e., white blood cells [WBCs], red blood cells [R...

journal_title：American journal of clinical pathology

authors： Warner BA,Reardon DM

更新日期：1991-02-01 00:00:00

abstract：:The ongoing collaborative relationship between a pathology department and the vendor of its laboratory information system is vitally important because of the strategic importance of the laboratory information system in managing the information product of the department. Laboratory information system vendors are value-...

journal_title：American journal of clinical pathology

authors： Friedman BA,Mitchell W

更新日期：1992-03-01 00:00:00

abstract：:Wild-type apolipoprotein A-I (apo A-I)-derived amyloid commonly occurs in atherosclerotic plaques. To clarify apo A-I amyloid formation, plasma levels of apo A-I and cholesterol were related to the presence of amyloid in atherosclerotic plaques in 15 patients with peripheral atherosclerosis, subjected to arterial reco...

journal_title：American journal of clinical pathology

authors： Mucchiano GI,Jonasson L,Häggqvist B,Einarsson E,Westermark P

更新日期：2001-02-01 00:00:00

abstract：:Interest in the role of mononuclear phagocytes in glomerulonephritis (GN) and in defining markers of renal neoplasms led the authors to study alpha-naphthyl acetate/butyrate esterase (ANAE/ANBE), alkaline phosphatase (AlkP), acid phosphatase (AcP), 5'-nucleotidase (5'N), and ATPase (ATP) activity in paraformaldehyde-f...

journal_title：American journal of clinical pathology

authors： Alpers CE,Beckstead JH

更新日期：1985-05-01 00:00:00

abstract：:Pretreatment posterior iliac crest bone marrow biopsies were obtained from 26 multiple myeloma patients. Biopsies were processed in methacrylate. The percentage of myeloma tissue, myeloid tissue, and fat was estimated in each biopsy. In 20 patients who died there was a positive correlation between the percent of myelo...

journal_title：American journal of clinical pathology

authors： Mahmoud LA,Block MH,Franks JJ,Sayed NM

更新日期：1983-09-01 00:00:00

abstract：:A primary hepatic tumor with histologic features suggestive of carcinoid tumor is reported, and six previously reported cases reviewed. Tumor cells contained electron dense secretory granules with an average diameter 150-200 nm which demonstrated positive argyrophilic reactions. On immunohistochemistry, chromogranin A...

journal_title：American journal of clinical pathology

authors： Miura K,Shirasawa H

更新日期：1988-04-01 00:00:00

abstract：:Lean methodologies have been applied in many industries to reduce waste. We applied Lean techniques to redesign laboratory workstations with the aim of reducing the number of times employees must leave their workstations to complete their tasks. At baseline in 68 workflows (aggregates or sequence of process steps) stu...

journal_title：American journal of clinical pathology

authors： Yerian LM,Seestadt JA,Gomez ER,Marchant KK

更新日期：2012-08-01 00:00:00

abstract：:We used a panel of paraffin antibodies to determine whether neoplastic and nonneoplastic lymphoid aggregates in the bone marrow can be distinguished reliably. Formalin-fixed, paraffin-embedded bone marrow core biopsy specimens with lymphoid aggregates were stained using primary antibodies directed against bcl-2, bcl-6...

journal_title：American journal of clinical pathology

authors： West RB,Warnke RA,Natkunam Y

更新日期：2002-04-01 00:00:00

abstract：:The characteristics of the normal adult thymus in both sexes were determined in 50 cases of accidental death by a simplified quantitative histologic technic. A table of normal values derived from these findings was used for making comparisons with thymus from autopsies of 50 additional patients suffering terminal illn...

journal_title：American journal of clinical pathology

authors： Smith SM,Ossa-Gomez LJ

更新日期：1981-11-01 00:00:00

abstract：OBJECTIVES:Lymphoid enhancer binding factor 1 (LEF1) is expressed in most cases of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and has shown utility in distinguishing CLL/SLL from other small B-cell lymphomas. LEF1 expression has not been systematically studied in CD5-positive marginal zone lympho...

journal_title：American journal of clinical pathology

authors： Patel N,Durkin L,Bodo J,Hsi ED

更新日期：2020-04-15 00:00:00

abstract：:Twenty-five cases of tubal or tubo-endometrioid metaplasia that occurred in patients from 21 to 51 years of age (mean 39 years) are described. The majority of the cases were seen in consultation. They were referred because of diagnostic problems resulting from features that have received little emphasis. The metaplasi...

journal_title：American journal of clinical pathology

authors： Oliva E,Clement PB,Young RH

更新日期：1995-05-01 00:00:00

abstract：:We describe a method of spectrophotometric detection of BCR/ABL chimeric sequences amplified by multiplex reverse transcriptase-polymerase chain reaction (RT-PCR), enabling the use of archival hematologic slides as RNA sources. Multiplex PCR amplified b3a2, b2a2, and e1a2 break points of the BCR/ABL translocation and ...

journal_title：American journal of clinical pathology

authors： Attadia V,Alosi M,Improta S,Zagonel V,Martinazzo G,Carbone A,Pinto A

更新日期：1997-10-01 00:00:00

abstract：:The serum concentrations of alpha-fetoprotein of rats following experimental galactosamine-induced liver-cell necrosis accurately reflect the severity of preceding liver-cell damage as determined by elevation of serum transaminases. There is a very close correlation between the highest SGOT or SGPT serum activity foun...

journal_title：American journal of clinical pathology

authors： Sell S,Stillman D,Gochman N

更新日期：1976-11-01 00:00:00

abstract：:The "floral" variant of follicle center lymphoma (FCL) may be confused with progressive transformation of germinal centers or lymphocyte predominance Hodgkin lymphoma. Immunohistochemistry and gene rearrangement studies are usually sufficient to differentiate among these entities. We present 11 cases of floral FCL tha...

journal_title：American journal of clinical pathology

authors： Tiesinga JJ,Wu CD,Inghirami G

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVES:Luminex-based single-antigen bead human leukocyte antigen (HLA) antibody testing is widely used to define HLA antibodies for transplant compatibility. False-negative results can occur with complement-mediated prozone inhibition. This study assessed the effect of EDTA on the assay background reactivity and fl...

journal_title：American journal of clinical pathology

authors： Anani WQ,Zeevi A,Lunz JG

更新日期：2016-09-01 00:00:00

abstract：:In 1985 Harvard Medical School initiated an experimental curriculum that incorporated many of the recommendations of the report on the General Professional Education of the Physician (GPEP). Key features are problem-based small group tutorials that emphasize active learning, with increased independent study time and a...

journal_title：American journal of clinical pathology

authors： Colvin RB,Wetzel MS

更新日期：1989-10-01 00:00:00