Effect of glucosphingolipid synthesis inhibitor (PPMP and PDMP) treatment on Tetrahymena pyriformis: data on the evolution of the signaling system.

abstract：:The erythrocytes of mammals represent a good model to evaluate the cytotoxicity of molecules, organic and inorganic, natural or synthetic, by cellular damage measure. Indeed, before any investigation on the mechanism of action of different molecules, it is important to perform a cytotoxicity assay. Among the different...

journal_title：Cell biochemistry and function

authors： Pagano M,Faggio C

更新日期：2015-08-01 00:00:00

abstract：:Using several physical techniques the surface of articular cartilage has been reported to be structurally different from the deeper layers. In this paper using immunohistochemical methods, the surface has been shown to contain a characteristically different collagen, Type I in contrast to Type II which is the major co...

journal_title：Cell biochemistry and function

authors： Duance VC

更新日期：1983-10-01 00:00:00

abstract：:The aim of this brief communication was to determine the correlation between pre-eclampsia (PE), Helicobacter pylori pathogenic strains seropositivity, and interleukin-18 (IL-18) levels. To this purpose 25 pre-eclamptic women and 25 healthy parturient women of similar age were evaluated for: IL-18 levels, by ELISAH. p...

journal_title：Cell biochemistry and function

authors： Pugliese A,Beltramo T,Todros T,Cardaropoli S,Ponzetto A

更新日期：2008-10-01 00:00:00

abstract：:Glioma is one of the most common brain tumors and one of the most aggressive cancers. Although extensive progress has been made regarding to the diagnosis and treatment, the mortality in glioma patients is still high. Therefore, finding new therapeutic targets to the glioma is critical to the advancement in cancer tre...

journal_title：Cell biochemistry and function

authors： Wu H,Li J,Xu D,Jv D,Meng X,Qiao P,Cui T,Shi B

更新日期：2016-10-01 00:00:00

abstract：:Sexually-transmitted diseases (STD) can facilitate the progression of HIV-1 infection. Among them, as we have previously demonstrated, cervico-vaginal dysplasia-papillomavirus (HPV)-induced, together with HSV-2 co-infection, seems to be correlated with a more evident immunodepression in HIV-positive women, compared wi...

journal_title：Cell biochemistry and function

authors： Pugliese A,Andronico L,Gennero L,Pagliano G,Gallo G,Torre D

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the effect of artemisinin on the proliferation and apoptosis of rat vascular smooth muscle cells (VSMCs). METHOD:Primary rat VSMCs were treated with various doses of artemisinin. Cell proliferation was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bro...

journal_title：Cell biochemistry and function

authors： Wang HY,Huang RP,Han P,Xue DB,Li HB,Liu B,Shan P,Wang QS,Li KS,Li HL

更新日期：2014-03-01 00:00:00

abstract：:The MCF-7 human breast carcinoma cell line is widely used as a model system by breast cancer researchers and cell biologists investigating apoptosis. Since its establishment 30 years ago, from a patient with metastatic breast cancer, the original MCF-7 cell population has undergone genetic drift to such an extent that...

journal_title：Cell biochemistry and function

authors： Rintala-Maki ND,Abrasonis V,Burd M,Sutherland LC

更新日期：2004-09-01 00:00:00

abstract：:The effects of Alpinia protocatechuic acid (PCA) on spleen and liver antioxidant system in aged rats have been studied. Alpinia PCA, a phenolic compound, was first isolated from the dried fruits of Alpinia Oxyphylla Miq. in our laboratory. Young and aged rats were injected intraperitoneally with Alpinia PCA at single ...

journal_title：Cell biochemistry and function

authors： Zhang X,Shi GF,Liu XZ,An LJ,Guan S

更新日期：2011-06-01 00:00:00

abstract：:Regeneration remains a major challenge in skeletal muscle repair after injury. Recently, transforming growth factor-β (TGF-β)/Smad pathway was found to play an important role in inhibiting myogenesis, a crucial stage in skeletal muscle regeneration. In our previous study, microRNA-122-5p (miR-122) was proved to have t...

journal_title：Cell biochemistry and function

authors： Ding Z,Lin J,Sun Y,Cong S,Liu S,Zhang Y,Chen Q,Chen J

更新日期：2020-03-01 00:00:00

abstract：:The protective effects of carnosine as a natural dipeptide were investigated in mouse bone marrow cells against genotoxicity induced by cyclophosphamide. Mice were injected with solutions of carnosine at three different doses (10, 50 and 100 mg kg(-1) bw) for five consecutive days. On the fifth day of treatment, mice ...

journal_title：Cell biochemistry and function

authors： Naghshvar F,Abianeh SM,Ahmadashrafi S,Hosseinimehr SJ

更新日期：2012-10-01 00:00:00

abstract：:Psoriasis is a common chronic and recurrent inflammatory skin disease with unknown etiology that has been associated with abnormal plasma lipid metabolism and oxidative stress. There are controversial results in the previous studies investigating oxidant/antioxidant systems in psoriasis.The aim of this work was to eva...

journal_title：Cell biochemistry and function

authors： Toker A,Kadi M,Yildirim AK,Aksoy H,Akçay F

更新日期：2009-04-01 00:00:00

abstract：:Metabolism of arabinose 5-P, ribose 5-P and glucose 6-P in permeabilized and resealed Morris hepatoma 5123TC cells was investigated by measuring the contribution of these compounds to nucleic acid biosynthesis. The level of [14C]-arabinose (non-phosphorylated) incorporation into nucleic acids was slight, presumably du...

journal_title：Cell biochemistry and function

authors： Arora KK,Williams JF

更新日期：1987-10-01 00:00:00

abstract：:Retinopathy of prematurity, a leading cause of visual impairment in low birth-weight infants, remains a crucial therapeutic challenge. Ciliary neurotrophic factor (CNTF) is a promyelinating trophic factor that promotes rod and cone photoreceptor survival and cone outer segment regeneration in the degenerating retina. ...

journal_title：Cell biochemistry and function

authors： Zhou WD,Wang LL,Zhou LB,Bin W,Bao TP,Zhang Y,Shu J,Yang WX,Hui LL,Jin R,Zhuang LL,Zhou GP

更新日期：2017-06-01 00:00:00

abstract：:The effect of citrinin on Ca2+ transport was studied in isolated kidney cortex and liver mitochondria, and baby hamster kidney cultured cells. The mycotoxin significantly inhibited the activity of 2-oxoglutarate and pyruvate dehydrogenases in both kidney cortex and liver mitochondria. Citrinin promoted a decrease in t...

journal_title：Cell biochemistry and function

authors： Chagas GM,Oliveira MA,Campello AP,Kluppel ML

更新日期：1995-03-01 00:00:00

abstract：:Although techniques for purifying epidermal stem cells (ESCs) have been established, enriching a pure population of viable ESCs is still a challenging task. One approach toward enhancing the purity and viability of ESCs involves cell markers. While evidence suggests that p63 plays a role in maintaining the population ...

journal_title：Cell biochemistry and function

authors： Tao Q,Qiao B,Lv B,Zheng C,Chen Z,Huang H

更新日期：2009-12-01 00:00:00

abstract：:Reduced and oxidized glutathione (GSH and GSSG), protein-bound glutathione, lipid peroxidation and antioxidant enzyme activities were determined in the erythrocyte lysates and membranes of type I and II alcoholics in order to clarify the effect of age-of-onset and the duration of the alcohol consumption on erythrocyte...

journal_title：Cell biochemistry and function

authors： Uçar G,Demir B,Uluğ B

更新日期：2005-01-01 00:00:00

abstract：:Epidermal growth factor plays a major role in breast cancer cell proliferation, survival, and metastasis. Quercetin, a bioactive flavonoid, is shown to exhibit anticarcinogenic effects against various cancers including breast cancer. Hence, the present study was designed to evaluate the effects of gold nanoparticles-c...

journal_title：Cell biochemistry and function

authors： Balakrishnan S,Mukherjee S,Das S,Bhat FA,Raja Singh P,Patra CR,Arunakaran J

更新日期：2017-06-01 00:00:00

abstract：:It is widely believed that selective packaging of nucleic acids, especially microRNAs, into exosomes secreted by the cancer cells not only ensures their growth and survival but also helps in the escape from immune surveillance. Keeping in view the fact that human cellular miR-2909 has emerged to regulate genes involve...

journal_title：Cell biochemistry and function

authors： Wani S,Kaul D

更新日期：2018-03-01 00:00:00

abstract：:Cyclophilin A (Cyp A), a member of the peptidyl-prolyl isomerase (PPI) family, may function as a molecular signalling switch. Comparative proteomic studies have identified Cyp A as a potential downstream target of protein kinase B (Akt). This study confirmed that Cyp A is a downstream effector of the phosphatidylinosi...

journal_title：Cell biochemistry and function

authors： Lin ZL,Wu HJ,Chen JA,Lin KC,Hsu JH

更新日期：2015-12-01 00:00:00

abstract：:Endothelial dysfunction is recognized as the initial detectable stage of cardiovascular disease, a serious complication of diabetes. In this study, we evaluated effects of myricetin on high glucose (HG)-elicited oxidative damage in human umbilical vein endothelial cells (HUVECs). The cells were pre-incubated with myri...

journal_title：Cell biochemistry and function

authors： Aminzadeh A,Bashiri H

更新日期：2020-01-01 00:00:00

abstract：:Analysis of free nucleotide composition of both avian thrombocytes and pig platelets showed quantitative differences in the level of adenine nucleotides. 3H-adenine taken up by turkey thrombocytes was metabolized mainly to adenine nucleotides was not released after thrombin action. Thrombin liberated non-radioactive a...

journal_title：Cell biochemistry and function

authors： Wachowicz B

更新日期：1984-07-01 00:00:00

abstract：:Several studies have highlighted the potential of leucine supplementation for the treatment of metabolic diseases including type 2 diabetes and obesity. Caloric restriction is a common approach to improve the health in diabetic and obese subjects. However, very few studies assessed the effects of leucine supplementati...

journal_title：Cell biochemistry and function

authors： Pedroso JA,Nishimura LS,de Matos-Neto EM,Donato J Jr,Tirapegui J

更新日期：2014-06-01 00:00:00

abstract：:The effects of either radiation or hyperthermia on the differentiation potential of NG108-15, a neuroblastoma-glioma hybrid cell line, were studied. After radiation and hyperthermia, the outgrowth of neurites from NG108-15 cells was potentiated, and polarizing current and voltage pulses induced a distinct action poten...

journal_title：Cell biochemistry and function

authors： Sugihara M,Fujita Y,Enomoto K,Maeno T,Ishida T

更新日期：1994-06-01 00:00:00

abstract：:The effect of exposure to, followed by consumption of, 10% flax chow from the 18th day of gestation to the 86th day after birth was examined in male and female Fischer 344 rats. Growth curves of the flax chow-fed rats were identical to those of regular chow-fed rats, as were such developmental milestones as pinna deve...

journal_title：Cell biochemistry and function

authors： Hemmings SJ,Barker L

更新日期：2004-03-01 00:00:00

abstract：:Research on prostate cancer progression has focused extensively on the concept of miRNA, which can operate either as promoters or as suppressors of carcinogenesis. Moreover, recent genetic studies and emerging functional work show that strikingly similar and overlapping pathways are involved in prostate carcinogenesis...

journal_title：Cell biochemistry and function

authors： Farooqi AA,Naqi A,Qureshi MZ,Rana A,Khan A,Riaz AM,Afzal SM,Rasheed N,Bhatti S

更新日期：2012-10-01 00:00:00

abstract：:The aim of the present work was to investigate the mechanisms of oxidative damage of the liver mitochondria under diabetes and intoxication in rats as well as to evaluate the possibility of corrections of mitochondrial disorders by pharmacological doses of melatonin. The experimental (30 days) streptozotocin-induced d...

journal_title：Cell biochemistry and function

authors： Cheshchevik VT,Dremza IK,Lapshina EA,Zabrodskaya SV,Kujawa J,Zavodnik IB

更新日期：2011-08-01 00:00:00

abstract：:A method for the quantification of energy consuming processes described by Siems et al. for reticulocytes and by Müller et al. for ascites tumour cells was applied to balance the ATP-consumption of isolated rat hepatocytes. On the basis of decreased coupled respiration rates following the specific inhibition of energy...

journal_title：Cell biochemistry and function

authors： Schneider W,Siems W,Grune T

更新日期：1990-10-01 00:00:00

abstract：:Glucocorticoids are important for skeletal muscle energy metabolism, regulating glucose utilization, insulin sensitivity, and muscle mass. Nicotinamide adenine dinucleotide phosphate-dependent 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)-mediated glucocorticoid activation in the sarcoplasmic reticulum (SR) is in...

journal_title：Cell biochemistry and function

authors： Zielinska AE,Fletcher RS,Sherlock M,Doig CL,Lavery GG

更新日期：2017-07-01 00:00:00

abstract：:The microsomes from dehydroepiandrosterone (DHEA)-supplemented animals are good hydroxyl radical scavengers, as demonstrated through electron spin resonance and deoxyribose degradation. The ability of DHEA-supplemented microsomes to react with superoxide radical was also demonstrated through the inhibition of nitroblu...

journal_title：Cell biochemistry and function

authors： Tamagno E,Aragno M,Boccuzzi G,Gallo M,Parola S,Fubini B,Poli G,Danni O

更新日期：1998-03-01 00:00:00

abstract：:This study evaluated the effect of possible synergic interaction between high fat diet (HF) and hydrochlorothiazide (HCTZ) on biochemical parameters of oxidative stress in brain. Rats were fed for 16 weeks with a control diet or with an HF, both supplemented with different doses of HCTZ (0.4, 1.0, and 4.0 g kg(-1) of ...

journal_title：Cell biochemistry and function

authors： Ribeiro MC,Barbosa NB,de Almeida TM,Parcianello LM,Perottoni J,de Avila DS,Rocha JB

更新日期：2009-10-01 00:00:00