Oxygen free radical scavenger properties of dehydroepiandrosterone.

abstract：:The phospholipid profiles of the myocardium (from 10- and 18-day old chick embryos and 13-day old chick) and their in vitro response to the endogenous lipolytic enzymes (mainly of the phospholipase group) at pH 7.4 and 38 degrees C for 60 min were analyzed by TLC technology and densitometry. Cardiolipin (CL) was shown...

journal_title：Cell biochemistry and function

authors： Helmy FM,Aikins A,Hughes J,Belfield C,Juracka A

更新日期：2007-09-01 00:00:00

abstract：:Several polymorphisms in the CYP1A1 locus have been identified and their genotypes appear to exhibit population frequencies that depend on ethnicity. We studied two CYP1A1 polymorphic sites (position 4889 and 6235) in a group of 212 unrelated healthy individuals belonging to three different Mexican populations (106 Me...

journal_title：Cell biochemistry and function

authors： Fragoso JM,Juárez-Cedillo T,Hernández-Pacheco G,Ramírez E,Zuñiga J,Izaguirre R,de la Peña A,Granados J,Vargas-Alarcón G

更新日期：2005-05-01 00:00:00

abstract：:The aim of the present work was to investigate the mechanisms of oxidative damage of the liver mitochondria under diabetes and intoxication in rats as well as to evaluate the possibility of corrections of mitochondrial disorders by pharmacological doses of melatonin. The experimental (30 days) streptozotocin-induced d...

journal_title：Cell biochemistry and function

authors： Cheshchevik VT,Dremza IK,Lapshina EA,Zabrodskaya SV,Kujawa J,Zavodnik IB

更新日期：2011-08-01 00:00:00

abstract：:Functional irregularities due to damage after ischaemia-reperfusion vary depending upon the organs affected. High energy phosphates such as ATP and ADP are destroyed after ischaemia-reperfusion damage. Subsequently, protons and inorganic phosphates accumulate within the cells and the proton pumps such as adenosine tri...

journal_title：Cell biochemistry and function

authors： Ilhan N,Halifeoglu I,Ozercan HI,Ilhan N

更新日期：2001-09-01 00:00:00

abstract：:We constructed the significant low-expression P-glycoprotein (ABCB1) inhibited transport and signal network in chimpanzee compared with high-expression (fold change ≥2) the human left cerebrum in GEO data set, by using integration of gene regulatory activated and inhibited network inference method with gene ontology (...

journal_title：Cell biochemistry and function

authors： Lin H,Wang L,Jiang M,Huang J,Qi L

更新日期：2012-10-01 00:00:00

abstract：:Extracellular acylglycerols are hydrolysed by lipases active at the surface of intact fat cells isolated from rat or human adipose tissue. During short-term incubation, rat fat cells hydrolyse di-[3H]oleyl-[14C]glycerol at a rate of 70 +/- 7.7 mU/10(6) cells (mean +/- S.E.) versus 440 +/- 62 mU/10(6) cells for the hyd...

journal_title：Cell biochemistry and function

authors： Verine A,Boyer J

更新日期：1987-07-01 00:00:00

abstract：:Recent studies have demonstrated that germ-like cells could be differentiated from human umbilical cord mesenchymal stem cells (hUC-MSCs) in vitro. Whether the sexuality of hUC-MSCs affects the formation efficiency of germ-like cells derived from hUC-MSCs is still unclear. To clearly test the formation efficiency of o...

journal_title：Cell biochemistry and function

authors： Qiu P,Bai Y,Pan S,Li W,Liu W,Hua J

更新日期：2013-07-01 00:00:00

abstract：:In response to concanavalin A, cytoplasmic calcium movement was observed in human platelets, both in the presence of 1 mM Ca2+ or 1 mM EGTA in the medium. Concanavalin A also caused the activation of inositide turnover and the production of inositol phosphates, suggesting that activation of phospholipase C occurs. The...

journal_title：Cell biochemistry and function

authors： Torti M,Balduini C,Ramaschi G,Sinigaglia F

更新日期：1992-03-01 00:00:00

abstract：:We investigated the effect of rosiglitazone (RSG), a high-affinity ligand for the peroxisome proliferator-activated receptor gamma which mediates insulin-sensitizing actions, on the lipid profile and oxidative status in streptozotocin (STZ)-induced Type 2 diabetes mellitus (DM) rats. Wistar albino male rats were rando...

journal_title：Cell biochemistry and function

authors： Kavak S,Ayaz L,Emre M,Inal T,Tamer L,Günay I

更新日期：2008-06-01 00:00:00

abstract：:During remodelling of pulmonary artery, marked proliferation of pulmonary artery smooth muscle cells (PASMCs) occurs, which contributes to pulmonary hypertension. Thromboxane A2 (TxA2) has been shown to produce pulmonary hypertension. The present study investigates the inhibitory effect of epigallocatechin-3-gallate (...

journal_title：Cell biochemistry and function

authors： Chowdhury A,Sarkar J,Chakraborti T,Chakraborti S

更新日期：2015-10-01 00:00:00

abstract：:The main purpose of the present investigation was to study the effect of cloturin on aerobic glycolysis, endogenous and exogenous respiration and the level of ATP in both Ehrlich ascites carcinoma (EAC) and P388 murine leukaemia cells incubated in vitro. Also its effect on the level of total (T-SH) and non-protein (NP...

journal_title：Cell biochemistry and function

authors： Miko M,Krepelka J,Melka M

更新日期：1992-06-01 00:00:00

abstract：:Rat liver mitochondria were stored at 0-4 degrees C for several days using an appropriate medium and energy source. The elimination of the majority of microsomes and lysosomes, that normally contaminate isolated mitochondria, had a positive effect in preservation of respiratory control, P:O ratio, and monoamine oxidas...

journal_title：Cell biochemistry and function

authors： Higuti IH,Murata LY,Stencel M,De Paiva Campello A,Do Nascimento AJ

更新日期：1985-10-01 00:00:00

abstract：:The p53 protein plays a critical role in suppression of tumour growth; its regulation is not fully understood. Leukaemia/lymphoma-related factor (LRF) promotes tumour cell growth. This study tests a hypothesis that LRF inhibits p53 expression in colon cancer cells. In this study, human colon cancer cell lines, LIM1215...

journal_title：Cell biochemistry and function

authors： Zhu M,Wang P,Feng F,Li MY

更新日期：2017-10-01 00:00:00

abstract：:In pancreatic islets prepared from fed rats and incubated at a low concentration (1.7 mM) of D-glucose, D-mannoheptulose (10.0 mM) virtually fails to affect the metabolism of the hexose. Likewise, in islets from starved rats, the relative extent of the inhibitory action of D-mannoheptulose upon D-glucose metabolism is...

journal_title：Cell biochemistry and function

authors： Picton S,Malaisse WJ

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the effect of artemisinin on the proliferation and apoptosis of rat vascular smooth muscle cells (VSMCs). METHOD:Primary rat VSMCs were treated with various doses of artemisinin. Cell proliferation was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bro...

journal_title：Cell biochemistry and function

authors： Wang HY,Huang RP,Han P,Xue DB,Li HB,Liu B,Shan P,Wang QS,Li KS,Li HL

更新日期：2014-03-01 00:00:00

abstract：:Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer, and thymidine phosphorylase (TP) is a regulator of angiogenesis. To investigate the biological activities of TP in ICC, we established human cholangiocarcinoma RBE cell lines overexpressing TP or silencing TP. Overexpression of TP en...

journal_title：Cell biochemistry and function

authors： Li S,Yang H,Li K,Fan G,Deng L,Xu C

更新日期：2020-08-01 00:00:00

abstract：:The activity and hormonal regulation of NAD- and NADP-linked isocitrate dehydrogenase (EC.1.1.1.41 and EC.1.1.1.42, respectively) in the brain, liver and kidney cortex of female rats of various ages was investigated. The activity of NAD-ICDH of brain was greater than extramitochondrial (-c) or intramitochondrial (-m) ...

journal_title：Cell biochemistry and function

authors： Yadav RN

更新日期：1988-07-01 00:00:00

abstract：:The immunological induction of arthritis in the knee of the rabbit is well established as a model for human rheumatoid arthritis. It has the special advantage of allowing the development of the condition, and the effect of disease-modifying agents, to be followed. Attention has been focussed on the activity of glucose...

journal_title：Cell biochemistry and function

authors： Pitsillides AA,Blake SM,Glynn LE,Bitensky L,Chayen J

更新日期：1990-10-01 00:00:00

abstract：:Because of limited treatment options, preeclampsia (PE) is the leading cause of perinatal morbidity and mortality worldwide. Recently, lncRNA TDRG1 is reported to be aberrantly down-regulated in PE placenta, and the abnormal expression of TDRG1 might play a key or partial role in PE development. In this study, we foun...

journal_title：Cell biochemistry and function

authors： Gong F,Cheng H,Shi Y,Cui L,Jia G

更新日期：2020-06-01 00:00:00

abstract：:Voltage-gated Ca(2+) channels regulate cardiac automaticity, rhythmicity and excitation-contraction coupling. Whereas L-type (Cav 1·2, Cav 1·3) and T-type (Cav 3·1, Cav 3·2) channels are widely accepted for their functional relevance in the heart, the role of Cav 2·3 Ca(2+) channels expressing R-type currents remains ...

journal_title：Cell biochemistry and function

authors： Galetin T,Tevoufouet EE,Sandmeyer J,Matthes J,Nguemo F,Hescheler J,Weiergräber M,Schneider T

更新日期：2013-07-01 00:00:00

abstract：:Glucocorticoids are important for skeletal muscle energy metabolism, regulating glucose utilization, insulin sensitivity, and muscle mass. Nicotinamide adenine dinucleotide phosphate-dependent 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)-mediated glucocorticoid activation in the sarcoplasmic reticulum (SR) is in...

journal_title：Cell biochemistry and function

authors： Zielinska AE,Fletcher RS,Sherlock M,Doig CL,Lavery GG

更新日期：2017-07-01 00:00:00

abstract：:Glioma is one of the most common brain tumors and one of the most aggressive cancers. Although extensive progress has been made regarding to the diagnosis and treatment, the mortality in glioma patients is still high. Therefore, finding new therapeutic targets to the glioma is critical to the advancement in cancer tre...

journal_title：Cell biochemistry and function

authors： Wu H,Li J,Xu D,Jv D,Meng X,Qiao P,Cui T,Shi B

更新日期：2016-10-01 00:00:00

abstract：:Endometrial cancer (EC) is the most common gynaecologic malignancy in western countries and has been reported to account for about 7% of female malignant tumours and 20% to 30% of female genital system malignant tumours. Accumulating evidence showed the expression of human trophoblast cell surface antigen 2 (Trop2) wa...

journal_title：Cell biochemistry and function

authors： Sun X,Xing G,Zhang C,Lu K,Wang Y,He X

更新日期：2020-03-01 00:00:00

abstract：:Psoriasis is a common chronic and recurrent inflammatory skin disease with unknown etiology that has been associated with abnormal plasma lipid metabolism and oxidative stress. There are controversial results in the previous studies investigating oxidant/antioxidant systems in psoriasis.The aim of this work was to eva...

journal_title：Cell biochemistry and function

authors： Toker A,Kadi M,Yildirim AK,Aksoy H,Akçay F

更新日期：2009-04-01 00:00:00

abstract：:The ataxia-telangiectasia mutated (ATM) protein kinase is best known for its critical nuclear roles in the DNA damage response (DDR), cell cycle checkpoints, and the maintenance of gene stability. In this review, we highlight the multifaceted cytoplasmic functions of ATM in autophagy. We focused on the functions of AT...

journal_title：Cell biochemistry and function

authors： Liang N,He Q,Liu X,Sun H

更新日期：2019-04-01 00:00:00

abstract：:This study was designed to investigate the role of HO-1 induction in prevention of thioacetamide (TAA)-induced oxidative stress, inflammation and liver damage. The changes in hepatic dimethylarginine dimethylaminohydrolase (DDAH) activity as well as plasma arginine and asymmetric dimethylarginine (ADMA) levels were al...

journal_title：Cell biochemistry and function

authors： Develi-Is S,Bekpinar S,Kalaz EB,Evran B,Unlucerci Y,Gulluoglu M,Uysal M

更新日期：2013-03-01 00:00:00

abstract：:Diabetes induces oxidative stress in aged human and rat, although daily supplementation of vitamins C and E (VCE) can be beneficial to aged diabetic rats by reducing free radical production. The aim of the present study was to evaluate whether dietary VCE supplementation relieves oxidative stress in streptozotocin (ST...

journal_title：Cell biochemistry and function

authors： Özkaya D,Naziroğlu M,Armağan A,Demirel A,Köroglu BK,Çolakoğlu N,Kükner A,Sönmez TT

更新日期：2011-06-01 00:00:00

abstract：:The consumption of protein supplements containing amino acids is increasing around the world. Aspartate (Asp) and asparagine (Asn) are amino acids metabolized by skeletal muscle. This metabolism involves biochemical pathways that are involved in increasing Krebs cycle activity via anaplerotic reactions, resulting in h...

journal_title：Cell biochemistry and function

authors： Lancha AH Jr,Poortmans JR,Pereira LO

更新日期：2009-12-01 00:00:00

abstract：:Effects of methotrexate (MTX) on mitochondrial oxidative metabolism and ion transport were studied. MTX decreases the membrane potential (delta psi) upon energization of the mitochondrial membrane by NAD+-linked substrates and decreases the amplitude and velocity of swelling induced by glutamate and alpha-ketoglutarat...

journal_title：Cell biochemistry and function

authors： Yamamoto N,Lopes LC,Campello AP,Klüppel ML

更新日期：1989-04-01 00:00:00

abstract：:The effect of citrinin on Ca2+ transport was studied in isolated kidney cortex and liver mitochondria, and baby hamster kidney cultured cells. The mycotoxin significantly inhibited the activity of 2-oxoglutarate and pyruvate dehydrogenases in both kidney cortex and liver mitochondria. Citrinin promoted a decrease in t...

journal_title：Cell biochemistry and function

authors： Chagas GM,Oliveira MA,Campello AP,Kluppel ML

更新日期：1995-03-01 00:00:00