Mechanism of citrinin-induced dysfunction of mitochondria. IV--Effect on Ca2+ transport.

abstract：:The purpose of this study was to investigate the oxidative status in experimental hypothyroidism and the antioxidant effect of taurine supplementation. Forty male Sprague Dawley rats were randomly divided into four groups (group 1, control; group 2, control + taurine; group 3, propylthiouracil (PTU); group 4, PTU + ta...

journal_title：Cell biochemistry and function

authors： Taş S,Dirican M,Sarandöl E,Serdar Z

更新日期：2006-03-01 00:00:00

abstract：:Reactive oxygen species (ROS) have been implicated in the aetiology of several pathological and degenerative diseases. The protective effect of natural products possessing antioxidant properties has played a crucial role in ameliorating these deleterious effects. This study investigated the chemoprotective properties ...

journal_title：Cell biochemistry and function

authors： Adesanoye OA,Molehin OR,Delima AA,Adefegha AS,Farombi EO

更新日期：2013-10-01 00:00:00

abstract：:One of the most damaging effects of reactive oxygen species (ROS) is lipid peroxidation, the end-product of which is malondialdehyde (MDA). This study was aimed to evaluate erythrocyte MDA levels during fracture healing in rats. Thirty male rats were used and the rats were divided into two groups to serve as controls ...

journal_title：Cell biochemistry and function

authors： Yeler H,Tahtabas F,Candan F

更新日期：2005-03-01 00:00:00

abstract：:Indoleamine 2,3-dioxygenase (IDO) converts tryptophan to l-kynurenine, and it is noted as a relevant molecule in promoting tolerance and suppressing adaptive immunity. In this study, to investigate the effects of IDO in carbon tetrachloride (CCl(4) )-induced hepatitis model, the levels of IDO enzymic activities in the...

journal_title：Cell biochemistry and function

authors： Li D,Cai H,Hou M,Fu D,Ma Y,Luo Q,Yuan X,Lv M,Zhang X,Cong X,Lv Z

更新日期：2012-06-01 00:00:00

abstract：:In murine thymocytes cyclic nucleotide phosphodiesterase is represented by cAMP- and cGMP-specific forms. cAMP and cGMP phosphodiesterase activities showed anomalous kinetic behaviour indicative of 'low' and 'high' affinity enzyme forms. Sucrose density gradient centrifugation resolved only 'low' affinity forms of cAM...

journal_title：Cell biochemistry and function

authors： Sobolev AS,Rybalkin SD

更新日期：1986-07-01 00:00:00

abstract：:The new glass ionomer dental cement, ChemFil, was found to be moderately cytotoxic when freshly mixed in vitro. This was assessed by a reduction in fibroblast and macrophage counts following 24 h exposure to the material, and by alterations in enzyme levels and enzyme staining kinetics relative to control cultures. Te...

journal_title：Cell biochemistry and function

authors： Meryon SD,Browne RM

更新日期：1984-01-01 00:00:00

abstract：:Extracellular acylglycerols are hydrolysed by lipases active at the surface of intact fat cells isolated from rat or human adipose tissue. During short-term incubation, rat fat cells hydrolyse di-[3H]oleyl-[14C]glycerol at a rate of 70 +/- 7.7 mU/10(6) cells (mean +/- S.E.) versus 440 +/- 62 mU/10(6) cells for the hyd...

journal_title：Cell biochemistry and function

authors： Verine A,Boyer J

更新日期：1987-07-01 00:00:00

abstract：:Dexmedetomidine (DEX) is a highly selective α2 adrenoceptor agonist. In this study, we evaluated the antalgic effect of DEX on acetic acid-induced acute inflammatory visceral pain (AIVP) in rats. Additionally, we evaluated the role of Nrf2 signalling in antinociception. We administered acetic acid to male Sprague Dawl...

journal_title：Cell biochemistry and function

authors： Lan J,Zheng J,Feng J,Peng W

更新日期：2020-01-01 00:00:00

abstract：:Regulation of extracellular matrix (ECM) components is essential for tissue homeostasis and function. We screened a small peptide that induces ECM protein synthesis for its usefulness in protecting keratinocytes. In this report, we demonstrate that myristoyl tetrapeptide Ala-Ala-Pro-Val (mAAPV) stimulates the expressi...

journal_title：Cell biochemistry and function

authors： Kwon H,Lee YS,Kim MO,Chang MY,Won BM,Jin BS,Park S

更新日期：2014-12-01 00:00:00

abstract：:Familial Mediterranean Fever (FMF) is an autosomal recessive hereditary disease leading mostly to renal failure and nephrotic syndrome. The ultrastructure of kidney has not been fully investigated in FMF associated renal disease. The aim of this study is to provide further evidence on the ultrastructure of kidney in p...

journal_title：Cell biochemistry and function

authors： Kiliçaslan SM,Ayvali C,Taştan H

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the effect of artemisinin on the proliferation and apoptosis of rat vascular smooth muscle cells (VSMCs). METHOD:Primary rat VSMCs were treated with various doses of artemisinin. Cell proliferation was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bro...

journal_title：Cell biochemistry and function

authors： Wang HY,Huang RP,Han P,Xue DB,Li HB,Liu B,Shan P,Wang QS,Li KS,Li HL

更新日期：2014-03-01 00:00:00

abstract：:Free radicals are now well known to damage cellular components. To investigate whether age and thyroid level affect peroxidation speed, we examined the levels of malondialdehyde and antioxidant enzyme activities in different age groups of hypothyroid rats. Hypothyroidism was induced in 30- and 60-day-old Wistar Albino...

journal_title：Cell biochemistry and function

authors： Yilmaz S,Ozan S,Benzer F,Canatan H

更新日期：2003-12-01 00:00:00

abstract：:The MCF-7 human breast carcinoma cell line is widely used as a model system by breast cancer researchers and cell biologists investigating apoptosis. Since its establishment 30 years ago, from a patient with metastatic breast cancer, the original MCF-7 cell population has undergone genetic drift to such an extent that...

journal_title：Cell biochemistry and function

authors： Rintala-Maki ND,Abrasonis V,Burd M,Sutherland LC

更新日期：2004-09-01 00:00:00

abstract：:Growth factors are biologically-active mediators that bind to specific receptors on target cells and regulate genes involved in cell growth, wound healing and regeneration. In the case of wound healing, a proper wound dressing is needed to cover the wound area, protect the damaged tissue, and if possible to activate c...

journal_title：Cell biochemistry and function

authors： Grdisa M,Popović M,Hrzenjak T

更新日期：2004-11-01 00:00:00

abstract：:The levels of polyamines and their synthesizing enzymes in squamous cell carcinoma of prostate implanted in intact as well as castrated male rats were determined after certain hormonal manipulations. The tumour was found to grow with an identical rate in non-castrated and castrated rats. Polyamine content and activiti...

journal_title：Cell biochemistry and function

authors： Shukla GS,Singhal RL

更新日期：1985-07-01 00:00:00

abstract：:Cardiac hypertrophy is not only an adaptational state before heart failure but also is an independent risk factor for ischemia, arrhythmia, and sudden death. However, the direct effects of hypercholesterolemia on the myocardium and mechanisms are not completely understood. It has been demonstrated that peroxisome prol...

journal_title：Cell biochemistry and function

authors： Ren L,Li Y,Li Y,Tang R,Hu D,Sheng Z,Liu N

更新日期：2010-01-01 00:00:00

abstract：:Effects of methotrexate (MTX) on mitochondrial oxidative metabolism and ion transport were studied. MTX decreases the membrane potential (delta psi) upon energization of the mitochondrial membrane by NAD+-linked substrates and decreases the amplitude and velocity of swelling induced by glutamate and alpha-ketoglutarat...

journal_title：Cell biochemistry and function

authors： Yamamoto N,Lopes LC,Campello AP,Klüppel ML

更新日期：1989-04-01 00:00:00

abstract：:In response to concanavalin A, cytoplasmic calcium movement was observed in human platelets, both in the presence of 1 mM Ca2+ or 1 mM EGTA in the medium. Concanavalin A also caused the activation of inositide turnover and the production of inositol phosphates, suggesting that activation of phospholipase C occurs. The...

journal_title：Cell biochemistry and function

authors： Torti M,Balduini C,Ramaschi G,Sinigaglia F

更新日期：1992-03-01 00:00:00

abstract：:The effect of the tryptophan hydroxylase inhibitor, PCPA methylester, the serotonin reuptake inhibitor fluoxetine and MAO-A inhibitor clorgyline on the serotonin content of rat immune cells was studied, using labelled antibodies and flow cytometry. Each molecule significantly increased in males the serotonin concentra...

journal_title：Cell biochemistry and function

authors： Pállinger E,Csaba G

更新日期：2007-09-01 00:00:00

abstract：:1-Phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) and 1-phenyl-2-palmitoylamino-3-morpholino-1-propanol (PPMP) are structural analogues of ceramide; inhibiting UDP-glucose : ceramide glucosyltransferase. After treatment with these synthetic ceramide analogues the expression of glucosphingolipid decreases, while ...

journal_title：Cell biochemistry and function

authors： Kovács P,Pintér M,Csaba G

更新日期：2000-12-01 00:00:00

abstract：:UFD1L is the human homologue of the yeast ubiquitin fusion degradation 1 (Ufd1) gene and maps on chromosome 22q11.2 in the typically deleted region (TDR) for DiGeorge/velocardiofacial syndromes (DGS/VCFS). In yeast, Ufd1 protein is involved in a degradation pathway for ubiquitin fused products (UFD pathway). Several s...

journal_title：Cell biochemistry and function

authors： Amati F,Condò I,Conti E,Sangiuolo F,Dallapiccola B,Testi R,Novelli G

更新日期：2003-09-01 00:00:00

abstract：:The requirement of large amounts of the recombinant human bone morphogenetic protein-2 (BMP-2) produces a huge translational barrier for its routine clinical use due to high cost. This leads to an urgent need to develop alternative methods to lower costs and/or increase efficacies for using BMP-2. In this study, we de...

journal_title：Cell biochemistry and function

authors： Okada M,Sangadala S,Liu Y,Yoshida M,Reddy BV,Titus L,Boden SD

更新日期：2009-12-01 00:00:00

abstract：:The aim of this brief communication was to determine the correlation between pre-eclampsia (PE), Helicobacter pylori pathogenic strains seropositivity, and interleukin-18 (IL-18) levels. To this purpose 25 pre-eclamptic women and 25 healthy parturient women of similar age were evaluated for: IL-18 levels, by ELISAH. p...

journal_title：Cell biochemistry and function

authors： Pugliese A,Beltramo T,Todros T,Cardaropoli S,Ponzetto A

更新日期：2008-10-01 00:00:00

abstract：:This study was designed to investigate the role of HO-1 induction in prevention of thioacetamide (TAA)-induced oxidative stress, inflammation and liver damage. The changes in hepatic dimethylarginine dimethylaminohydrolase (DDAH) activity as well as plasma arginine and asymmetric dimethylarginine (ADMA) levels were al...

journal_title：Cell biochemistry and function

authors： Develi-Is S,Bekpinar S,Kalaz EB,Evran B,Unlucerci Y,Gulluoglu M,Uysal M

更新日期：2013-03-01 00:00:00

abstract：:Diabetes induces oxidative stress in aged human and rat, although daily supplementation of vitamins C and E (VCE) can be beneficial to aged diabetic rats by reducing free radical production. The aim of the present study was to evaluate whether dietary VCE supplementation relieves oxidative stress in streptozotocin (ST...

journal_title：Cell biochemistry and function

authors： Özkaya D,Naziroğlu M,Armağan A,Demirel A,Köroglu BK,Çolakoğlu N,Kükner A,Sönmez TT

更新日期：2011-06-01 00:00:00

abstract：:Several studies have highlighted the potential of leucine supplementation for the treatment of metabolic diseases including type 2 diabetes and obesity. Caloric restriction is a common approach to improve the health in diabetic and obese subjects. However, very few studies assessed the effects of leucine supplementati...

journal_title：Cell biochemistry and function

authors： Pedroso JA,Nishimura LS,de Matos-Neto EM,Donato J Jr,Tirapegui J

更新日期：2014-06-01 00:00:00

abstract：:Astroglial cells dispersed from newborn rat hemispheres were established in medium supplemented with 20 per cent fetal calf serum (FBS) and then grown to a confluent monolayer in the presence of 10 per cent FBS or charcoal-stripped FBS (CS). Type 1 astrocytes were subcultured and either maintained under the same condi...

journal_title：Cell biochemistry and function

authors： Carlo P,Del Rio M,Violani E,Sciaba L,Picotti GB

更新日期：1996-03-01 00:00:00

abstract：:The effect of exposure to, followed by consumption of, 10% flax chow from the 18th day of gestation to the 86th day after birth was examined in male and female Fischer 344 rats. Growth curves of the flax chow-fed rats were identical to those of regular chow-fed rats, as were such developmental milestones as pinna deve...

journal_title：Cell biochemistry and function

authors： Hemmings SJ,Barker L

更新日期：2004-03-01 00:00:00

abstract：:Human adipose-derived stromal/stem cells (ASC) have immunomodulatory properties and the potential to differentiate into several cell lines, important for application in regenerative medicine. However, the contamination with dermal fibroblasts (FIB) can impair the beneficial effects of ASC in cell therapy. It is then e...

journal_title：Cell biochemistry and function

authors： Abreu de Melo MI,da Silva Cunha P,Coutinho de Miranda M,Faraco CCF,Barbosa JL,da Fonseca Ferreira A,Kunrath Lima M,Faria JAQA,Rodrigues MÂ,de Goes AM,Gomes DA

更新日期：2021-01-03 00:00:00

abstract：:The ataxia-telangiectasia mutated (ATM) protein kinase is best known for its critical nuclear roles in the DNA damage response (DDR), cell cycle checkpoints, and the maintenance of gene stability. In this review, we highlight the multifaceted cytoplasmic functions of ATM in autophagy. We focused on the functions of AT...

journal_title：Cell biochemistry and function

authors： Liang N,He Q,Liu X,Sun H

更新日期：2019-04-01 00:00:00