Human adipose-derived stromal/stem cells are distinct from dermal fibroblasts as evaluated by biological characterization and RNA sequencing.

abstract：:Sprouty1 protein belongs to a family of receptor tyrosine kinase-mediated signaling inhibitors, whose members are usually regulated by growth factors to form a negative feedback loop. Correspondingly fluctuations of Sprouty1 mRNA in response to single growth factors have been observed. In this report, we investigate S...

journal_title：Cell biochemistry and function

authors： Kral RM,Mayer CE,Vanas V,Gsur A,Sutterlüty-Fall H

更新日期：2014-01-01 00:00:00

abstract：:The heart responds to an increased demand arising due to physiological stimuli or pathological insults by hypertrophy of myocytes. Reactive oxygen species (ROS) have recently been identified as the molecular intermediates in the translation of mechanical stimuli to cellular response. Different signal transduction path...

journal_title：Cell biochemistry and function

authors： Adiga IK,Nair RR

更新日期：2008-04-01 00:00:00

abstract：:Nuclear, chromatin and microsomal fractions were isolated from hepatocytes prepared from rats injected with [32P]O4(2-) and killed subsequently at times between 1 and 48 h. Specific activities of the total phospholipids (PL) were determined for each subcellular fraction. The major points noted were the initial specifi...

journal_title：Cell biochemistry and function

authors： Viola-Magni MP,Gahan PB,Albi E,Iapoce R,Gentilucci PF

更新日期：1986-10-01 00:00:00

abstract：:Cardiovascular diseases are known to be the most fatal diseases worldwide. Ischaemia/reperfusion (I/R) injury is at the centre of the pathology of the most common cardiovascular diseases. According to the World Health Organization estimates, ischaemic heart disease is the leading global cause of death, causing more th...

journal_title：Cell biochemistry and function

authors： Gunata M,Parlakpinar H

更新日期：2020-09-06 00:00:00

abstract：:Rat liver nonparenchymal cells (NPC) were prepared by pronase digestion and purified on discontinuous gradients on Nycodenz. Morphological and biochemical characterization of cell suspensions showed that they were free of contamination by hepatocytes. We have confirmed the usefulness of pyruvate kinase activity in mon...

journal_title：Cell biochemistry and function

authors： Rich K,Lodola A

更新日期：1989-10-01 00:00:00

abstract：:The molecular mechanisms involved in GPCR-initiated signaling cascades where the two receptors share the same signaling cascade, such as thyrotropin-releasing hormone (TRH) and angiotensin II (ANG II), are still far from being understood. Here, we analyzed hormone-induced Ca(2+) responses and the process of desensitiz...

journal_title：Cell biochemistry and function

authors： Ostasov P,Krusek J,Durchankova D,Svoboda P,Novotny J

更新日期：2008-03-01 00:00:00

abstract：:Mitochondrial, endoplasmic reticular and plasma membrane fractions were isolated by a new method from control male Fischer 344 rats and rats given CCl4 by gavage. After 1 h of CCl4 treatment, rats were in glucose and pancreatic hormone balance but plasma levels of T3 and T4 were decreased 29 and 22%, respectively. Aft...

journal_title：Cell biochemistry and function

authors： Hemmings SJ,Pulga VB,Tran ST,Uwiera RR

更新日期：2002-03-01 00:00:00

abstract：:The aim of the present study was to measure plasma uric acid (UA) levels and superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and xanthine oxidase (XO) activities and to evaluate the relationship between these parameters and the severity of pre-eclampsia. Twenty-five pre-eclamptic, 15 healthy pregnant and 1...

journal_title：Cell biochemistry and function

authors： Yildirim A,Altinkaynak K,Aksoy H,Sahin YN,Akcay F

更新日期：2004-07-01 00:00:00

abstract：:CYR61 is one of the six proteins of the CCN family of proteins known to play diverse roles in angiogenesis, cellular proliferation, survival, migration and wound healing. However, the specific function of CYR61 in cancer is unclear, and the literature remains controversial. We used quantitative real-time PCR to establ...

journal_title：Cell biochemistry and function

authors： Jandova J,Beyer TE,Meuillet EJ,Watts GS

更新日期：2012-12-01 00:00:00

abstract：:In response to concanavalin A, cytoplasmic calcium movement was observed in human platelets, both in the presence of 1 mM Ca2+ or 1 mM EGTA in the medium. Concanavalin A also caused the activation of inositide turnover and the production of inositol phosphates, suggesting that activation of phospholipase C occurs. The...

journal_title：Cell biochemistry and function

authors： Torti M,Balduini C,Ramaschi G,Sinigaglia F

更新日期：1992-03-01 00:00:00

abstract：OBJECTIVE:Hydrogen peroxide (H(2)O(2)) is a potent reactive oxygen species that causes cardiomyocytes injury. As an important cytokine, interleukin 6 (IL-6) has cardioprotective effects as it plays an essential role in the late phase of preconditioning. Our work is to investigate if IL-6 preconditioning has protective ...

journal_title：Cell biochemistry and function

authors： Jia Y,Zhou F,Deng P,Fan Q,Li C,Liu Y,Fu X,Zhou Y,Xu X,Sun X

更新日期：2012-07-01 00:00:00

abstract：:CD36, a multifunctional adhesion receptor e.g. for thrombospondin and collagen, as well as a scavenger receptor for oxidized low density lipoprotein, is expressed e.g. on platelets and monocytes. By this dual role it might be involved in early steps of atherosclerosis like the recruitment of monocytes and formation of...

journal_title：Cell biochemistry and function

authors： Pietsch A,Weber C,Goretzki M,Weber PC,Lorenz RL

更新日期：1995-09-01 00:00:00

abstract：:This study was designed to investigate the effect of L-carnitine in ischaemia and reperfusion of the rat kidney. Rats were randomly allocated into three groups. Group I (control group; n = 6) received no treatment. Group II (isotonic saline group; n = 6), received 2 ml of isotonic saline 15 min before the renal ischae...

journal_title：Cell biochemistry and function

authors： Görür S,Bağdatoğlu OT,Polat G

更新日期：2005-05-01 00:00:00

abstract：:Current studies have shown that circular RNAs (circRNAs) and microRNAs (miRNAs) are closely related in acute myocardial infarction (AMI). Previous studies have shown that miR-125b promotes fibrosis and up-regulates in cardiac fibroblasts (CFs), and further experiments showed that circ_LAS1L had multiple binding sites ...

journal_title：Cell biochemistry and function

authors： Sun LY,Zhao JC,Ge XM,Zhang H,Wang CM,Bie ZD

更新日期：2020-06-01 00:00:00

abstract：:We report a functional characterisation of the novel protein MGC13096. MGC13096 over-expression restrained proliferation of HEK293T cells. DNA/flow cytometry analysis showed that the over-expression of MGC13096 severely delays cell cycle progression at S phase. Transcription factors such as activator protein-1 (AP-1),...

journal_title：Cell biochemistry and function

authors： Chen Q,Yan C,Yan Q,Feng L,Chen J,Qian K

更新日期：2008-03-01 00:00:00

abstract：:Cyclophosphamide (CP) has potential urotoxicity such as hemorrhagic cystitis (HC). 2-Mercaptoethane sulfonate (mesna) has been widely used as an effective agent against CP-induced cystitis, but significant HC has still been encountered clinically. In recent studies, mesna was shown to be more effective if combined wit...

journal_title：Cell biochemistry and function

authors： Sadir S,Deveci S,Korkmaz A,Oter S

更新日期：2007-09-01 00:00:00

abstract：:Voltage-gated Ca(2+) channels regulate cardiac automaticity, rhythmicity and excitation-contraction coupling. Whereas L-type (Cav 1·2, Cav 1·3) and T-type (Cav 3·1, Cav 3·2) channels are widely accepted for their functional relevance in the heart, the role of Cav 2·3 Ca(2+) channels expressing R-type currents remains ...

journal_title：Cell biochemistry and function

authors： Galetin T,Tevoufouet EE,Sandmeyer J,Matthes J,Nguemo F,Hescheler J,Weiergräber M,Schneider T

更新日期：2013-07-01 00:00:00

abstract：:Cardiac hypertrophy is not only an adaptational state before heart failure but also is an independent risk factor for ischemia, arrhythmia, and sudden death. However, the direct effects of hypercholesterolemia on the myocardium and mechanisms are not completely understood. It has been demonstrated that peroxisome prol...

journal_title：Cell biochemistry and function

authors： Ren L,Li Y,Li Y,Tang R,Hu D,Sheng Z,Liu N

更新日期：2010-01-01 00:00:00

abstract：:Melanin plays an important role in determining skin colour. Apoptosis of melanocytes and defect in melanin production cause vitiligo. Various studies have been conducted to treat the disease, but its treatment is still difficult. Therefore, this study aimed to investigate the effect of spermidine, which is known as an...

journal_title：Cell biochemistry and function

authors： Kang SH,Kim MM

更新日期：2021-01-25 00:00:00

abstract：:Bronchopulmonary dysplasia (BPD) is a common complication of premature birth that seriously affects the survival rate and quality of life among preterm neonates. Long non-coding RNAs (lncRNAs) have been implicated in many human diseases. However, the role of lncRNAs in the pathogenesis of BPD remains poorly understood...

journal_title：Cell biochemistry and function

authors： Bao TP,Wu R,Cheng HP,Cui XW,Tian ZF

更新日期：2016-07-01 00:00:00

abstract：:In this study, immunolocalization of tenascin (TN), type IV collagen and histopathological changes in the liver of fetuses of pregnant Wistar albino rats treated with two doses of alcohol (1 and 5 g kg(-1) day(-1)) were determined. The samples of liver obtained from fetuses of rats on day 21 of gestation were evaluate...

journal_title：Cell biochemistry and function

authors： Koçkaya EA,Akay MT

更新日期：2006-05-01 00:00:00

abstract：:Retinopathy of prematurity, a leading cause of visual impairment in low birth-weight infants, remains a crucial therapeutic challenge. Ciliary neurotrophic factor (CNTF) is a promyelinating trophic factor that promotes rod and cone photoreceptor survival and cone outer segment regeneration in the degenerating retina. ...

journal_title：Cell biochemistry and function

authors： Zhou WD,Wang LL,Zhou LB,Bin W,Bao TP,Zhang Y,Shu J,Yang WX,Hui LL,Jin R,Zhuang LL,Zhou GP

更新日期：2017-06-01 00:00:00

abstract：:The p53 protein plays a critical role in suppression of tumour growth; its regulation is not fully understood. Leukaemia/lymphoma-related factor (LRF) promotes tumour cell growth. This study tests a hypothesis that LRF inhibits p53 expression in colon cancer cells. In this study, human colon cancer cell lines, LIM1215...

journal_title：Cell biochemistry and function

authors： Zhu M,Wang P,Feng F,Li MY

更新日期：2017-10-01 00:00:00

abstract：:Glaucoma is optic neuropathy that is characterized by progressive neurodegeneration of the retinal ganglion cells (RGCs) and axons. This condition will lead to visual impairment and bring glaucoma to become the second cause of blindness globally. Neuroprotection in glaucoma is needed to prevent the progression of opti...

journal_title：Cell biochemistry and function

authors： Ko JA,Komatsu K,Okumichi H,Kiuchi Y

更新日期：2021-01-01 00:00:00

abstract：:The acute effects of isolated and combined L-alanine (L-Ala) and L-glutamine (L-Gln) on liver gluconeogenesis, ureagenesis and glycaemic recovery during short-term insulin-induced hypoglycaemia (IIH) were investigated. For this purpose, 24-h fasted rats that received intraperitoneal injection of regular insulin (1.0 U...

journal_title：Cell biochemistry and function

authors： Gazola VA,Garcia RF,Curi R,Pithon-Curi TC,Mohamad MS,Hartmann EM,Barrena HC,Bazotte RB

更新日期：2007-03-01 00:00:00

abstract：:We studied the effect of PTH (10-100 nM) on transductive mechanisms (adenylate cyclase activity, Ca2+ metabolism, IP3 levels) in cell cultures derived from normal and otosclerotic human bone fragments. The cultured cells were osteoblast-like but with calcitonin-receptors still present and with PTH receptors coupled wi...

journal_title：Cell biochemistry and function

authors： Fanó G,Venti-Donti G,Belia S,Paludetti G,Antonica A,Donti E,Maurizi M

更新日期：1993-12-01 00:00:00

abstract：:To determine the temporal roles of phosphatidylinositol 3-kinase (PI3-kinase) and phospholipase D (PLD) during human neutrophil activation stimulated by a chemotactic peptide, we examined the kinetics of these enzymes and related them to a neutrophil function (superoxide production). Both wortmannin and 2-(4-morpholin...

journal_title：Cell biochemistry and function

authors： Yasui K,Komiyama A

更新日期：2001-03-01 00:00:00

abstract：:Functional irregularities due to damage after ischaemia-reperfusion vary depending upon the organs affected. High energy phosphates such as ATP and ADP are destroyed after ischaemia-reperfusion damage. Subsequently, protons and inorganic phosphates accumulate within the cells and the proton pumps such as adenosine tri...

journal_title：Cell biochemistry and function

authors： Ilhan N,Halifeoglu I,Ozercan HI,Ilhan N

更新日期：2001-09-01 00:00:00

abstract：:Ovarian cancer is one of the most common female malignancies, and cisplatin-based chemotherapy is routinely used in locally advanced ovarian cancer patients. Acquired or de novo cisplatin resistance remains the barrier to patient survival, and the mechanisms of cisplatin resistance are still not well understood. In th...

journal_title：Cell biochemistry and function

authors： Yu R,Jin H,Jin C,Huang X,Lin J,Teng Y

更新日期：2018-03-01 00:00:00

abstract：:The modification of myeloperoxidase and lactoperoxidase with 2-(O-methoxypolethylene glycol)-4, 6-dichloro-s-triazine, an activated polyethylene glycol (PEG1), was investigated. The modification caused a shift of the Soret band in the light absorption spectrum, from 430 nm to 418 nm in the case of myeloperoxidase (nat...

journal_title：Cell biochemistry and function

authors： Odajima T,Onishi M

更新日期：1998-06-01 00:00:00