Cytochrome P450 in highly purified suspension of nonparenchymal liver cells.

abstract：:The ataxia-telangiectasia mutated (ATM) protein kinase is best known for its critical nuclear roles in the DNA damage response (DDR), cell cycle checkpoints, and the maintenance of gene stability. In this review, we highlight the multifaceted cytoplasmic functions of ATM in autophagy. We focused on the functions of AT...

journal_title：Cell biochemistry and function

authors： Liang N,He Q,Liu X,Sun H

更新日期：2019-04-01 00:00:00

abstract：:Endometrial cancer (EC) is the most common gynaecologic malignancy in western countries and has been reported to account for about 7% of female malignant tumours and 20% to 30% of female genital system malignant tumours. Accumulating evidence showed the expression of human trophoblast cell surface antigen 2 (Trop2) wa...

journal_title：Cell biochemistry and function

authors： Sun X,Xing G,Zhang C,Lu K,Wang Y,He X

更新日期：2020-03-01 00:00:00

abstract：:We investigated the effect of rosiglitazone (RSG), a high-affinity ligand for the peroxisome proliferator-activated receptor gamma which mediates insulin-sensitizing actions, on the lipid profile and oxidative status in streptozotocin (STZ)-induced Type 2 diabetes mellitus (DM) rats. Wistar albino male rats were rando...

journal_title：Cell biochemistry and function

authors： Kavak S,Ayaz L,Emre M,Inal T,Tamer L,Günay I

更新日期：2008-06-01 00:00:00

abstract：:Endothelial dysfunction is recognized as the initial detectable stage of cardiovascular disease, a serious complication of diabetes. In this study, we evaluated effects of myricetin on high glucose (HG)-elicited oxidative damage in human umbilical vein endothelial cells (HUVECs). The cells were pre-incubated with myri...

journal_title：Cell biochemistry and function

authors： Aminzadeh A,Bashiri H

更新日期：2020-01-01 00:00:00

abstract：:Liver-directed gene therapy has become a promising treatment for many liver diseases. In this study, we constructed a multi-functional targeting molecule, which maintains targeting, endosome-escaping, and DNA-binding abilities for gene delivery. Two single oligonucleotide chains of Melittin (M) were synthesized. The f...

journal_title：Cell biochemistry and function

authors： Wang W,Luo J,Xu L,Zeng J,Cao L,Dong J,Cai S

更新日期：2013-12-01 00:00:00

abstract：:The microsomes from dehydroepiandrosterone (DHEA)-supplemented animals are good hydroxyl radical scavengers, as demonstrated through electron spin resonance and deoxyribose degradation. The ability of DHEA-supplemented microsomes to react with superoxide radical was also demonstrated through the inhibition of nitroblu...

journal_title：Cell biochemistry and function

authors： Tamagno E,Aragno M,Boccuzzi G,Gallo M,Parola S,Fubini B,Poli G,Danni O

更新日期：1998-03-01 00:00:00

abstract：:Ceramide is known to trigger apoptosis of nucleated cells and eryptosis of erythrocytes. Eryptosis is characterized by cell shrinkage and cell membrane scrambling with phosphatidylserine translocation to the erythrocyte surface. Besides ceramide, stimulators of eryptosis include increase of cytosolic Ca(2+) -activity ...

journal_title：Cell biochemistry and function

authors： Signoretto E,Zierle J,Bhuyan AA,Castagna M,Lang F

更新日期：2016-07-01 00:00:00

abstract：:Metabolism of arabinose 5-P, ribose 5-P and glucose 6-P in permeabilized and resealed Morris hepatoma 5123TC cells was investigated by measuring the contribution of these compounds to nucleic acid biosynthesis. The level of [14C]-arabinose (non-phosphorylated) incorporation into nucleic acids was slight, presumably du...

journal_title：Cell biochemistry and function

authors： Arora KK,Williams JF

更新日期：1987-10-01 00:00:00

abstract：:The aim of our study was to evaluate the levels of fibronectin (FN) and its classic receptor (FNR) in various transformed cells lines, especially of leukemic origin, and also the influence of HIV-1 replication on the expression of these proteins (in particular on H9-V cells, chronically infected with HIV-1, and acutel...

journal_title：Cell biochemistry and function

authors： Pugliese A,Comito G,Savarino A,Cantamessa C,Torre D

更新日期：1996-06-01 00:00:00

abstract：:Dietary soy lecithin supplementation decreases hyperlipidemia and influences lipid metabolism. Although this product is used by diabetic patients, there are no data about the effect of soy lecithin supplementation on the immune system. The addition of phosphatidylcholine, the main component of lecithin, to a culture o...

journal_title：Cell biochemistry and function

authors： Miranda DT,Batista VG,Grando FC,Paula FM,Felício CA,Rubbo GF,Fernandes LC,Curi R,Nishiyama A

更新日期：2008-12-01 00:00:00

abstract：:MicroRNA (miRNAs) are short non-coding RNA molecules that downregulate gene expression at post-transcriptional level. miRNAs are post-transcriptional regulators of gene expression important for neuron development and function. This report demonstrated that a putative and chemically synthesized miRNA rno-mir-541 played...

journal_title：Cell biochemistry and function

authors： Zhang J,Zhang J,Liu LH,Zhou Y,Li YP,Shao ZH,Wu YJ,Li MJ,Fan YY,Shi HJ

更新日期：2011-06-01 00:00:00

abstract：:Growth factors are biologically-active mediators that bind to specific receptors on target cells and regulate genes involved in cell growth, wound healing and regeneration. In the case of wound healing, a proper wound dressing is needed to cover the wound area, protect the damaged tissue, and if possible to activate c...

journal_title：Cell biochemistry and function

authors： Grdisa M,Popović M,Hrzenjak T

更新日期：2004-11-01 00:00:00

abstract：:Astroglial cells dispersed from newborn rat hemispheres were established in medium supplemented with 20 per cent fetal calf serum (FBS) and then grown to a confluent monolayer in the presence of 10 per cent FBS or charcoal-stripped FBS (CS). Type 1 astrocytes were subcultured and either maintained under the same condi...

journal_title：Cell biochemistry and function

authors： Carlo P,Del Rio M,Violani E,Sciaba L,Picotti GB

更新日期：1996-03-01 00:00:00

abstract：:It is widely believed that selective packaging of nucleic acids, especially microRNAs, into exosomes secreted by the cancer cells not only ensures their growth and survival but also helps in the escape from immune surveillance. Keeping in view the fact that human cellular miR-2909 has emerged to regulate genes involve...

journal_title：Cell biochemistry and function

authors： Wani S,Kaul D

更新日期：2018-03-01 00:00:00

abstract：:We report a functional characterisation of the novel protein MGC13096. MGC13096 over-expression restrained proliferation of HEK293T cells. DNA/flow cytometry analysis showed that the over-expression of MGC13096 severely delays cell cycle progression at S phase. Transcription factors such as activator protein-1 (AP-1),...

journal_title：Cell biochemistry and function

authors： Chen Q,Yan C,Yan Q,Feng L,Chen J,Qian K

更新日期：2008-03-01 00:00:00

abstract：:Reactive oxygen species (ROS) have been implicated in the aetiology of several pathological and degenerative diseases. The protective effect of natural products possessing antioxidant properties has played a crucial role in ameliorating these deleterious effects. This study investigated the chemoprotective properties ...

journal_title：Cell biochemistry and function

authors： Adesanoye OA,Molehin OR,Delima AA,Adefegha AS,Farombi EO

更新日期：2013-10-01 00:00:00

abstract：:During remodelling of pulmonary artery, marked proliferation of pulmonary artery smooth muscle cells (PASMCs) occurs, which contributes to pulmonary hypertension. Thromboxane A2 (TxA2) has been shown to produce pulmonary hypertension. The present study investigates the inhibitory effect of epigallocatechin-3-gallate (...

journal_title：Cell biochemistry and function

authors： Chowdhury A,Sarkar J,Chakraborti T,Chakraborti S

更新日期：2015-10-01 00:00:00

abstract：:The aim of this study was to evaluate the role of mitochondria in the recovery of cardiac energetics induced by ischaemic preconditioning at reperfusion. Isolated rat hearts were aerobically perfused (control), subjected to global ischaemia and reperfusion (reperfusion), or subjected to 3 brief cycles of ischaemia/rep...

journal_title：Cell biochemistry and function

authors： Muscari C,Bonafè F,Gamberini C,Giordano E,Lenaz G,Caldarera CM

更新日期：2006-11-01 00:00:00

abstract：:CD36, a multifunctional adhesion receptor e.g. for thrombospondin and collagen, as well as a scavenger receptor for oxidized low density lipoprotein, is expressed e.g. on platelets and monocytes. By this dual role it might be involved in early steps of atherosclerosis like the recruitment of monocytes and formation of...

journal_title：Cell biochemistry and function

authors： Pietsch A,Weber C,Goretzki M,Weber PC,Lorenz RL

更新日期：1995-09-01 00:00:00

abstract：:Several studies have highlighted the potential of leucine supplementation for the treatment of metabolic diseases including type 2 diabetes and obesity. Caloric restriction is a common approach to improve the health in diabetic and obese subjects. However, very few studies assessed the effects of leucine supplementati...

journal_title：Cell biochemistry and function

authors： Pedroso JA,Nishimura LS,de Matos-Neto EM,Donato J Jr,Tirapegui J

更新日期：2014-06-01 00:00:00

abstract：:The aim of this experimental study was to investigate the possible role of adenosine deaminase (AD) and xanthine oxidase (XO) in the pathogenesis of cisplatin-induced nephrotoxicity and the effect of erdosteine in decreasing the toxicity. The intraperitoneal injection of cisplatin (7 mg kg(-1) body weight) induced a s...

journal_title：Cell biochemistry and function

authors： Söğüt S,Kotuk M,Yilmaz HR,Ulu R,Ozyurt H,Yildirim Z

更新日期：2004-05-01 00:00:00

abstract：:Free radicals are now well known to damage cellular components. To investigate whether age and thyroid level affect peroxidation speed, we examined the levels of malondialdehyde and antioxidant enzyme activities in different age groups of hypothyroid rats. Hypothyroidism was induced in 30- and 60-day-old Wistar Albino...

journal_title：Cell biochemistry and function

authors： Yilmaz S,Ozan S,Benzer F,Canatan H

更新日期：2003-12-01 00:00:00

abstract：:The heart responds to an increased demand arising due to physiological stimuli or pathological insults by hypertrophy of myocytes. Reactive oxygen species (ROS) have recently been identified as the molecular intermediates in the translation of mechanical stimuli to cellular response. Different signal transduction path...

journal_title：Cell biochemistry and function

authors： Adiga IK,Nair RR

更新日期：2008-04-01 00:00:00

abstract：:WIN55,212-2, a cannabinoid receptor agonist, can activate cannabinoid receptors, which has proven anti-tumour effects in several tumour types. Studies showed that WIN can inhibit tumour cell proliferation and induce apoptosis in diverse cancers. However, the role and mechanism of WIN in osteosarcoma are still unclear....

journal_title：Cell biochemistry and function

authors： Zhang G,Bi H,Gao J,Lu X,Zheng Y

更新日期：2016-07-01 00:00:00

abstract：:The activity and hormonal regulation of NAD- and NADP-linked isocitrate dehydrogenase (EC.1.1.1.41 and EC.1.1.1.42, respectively) in the brain, liver and kidney cortex of female rats of various ages was investigated. The activity of NAD-ICDH of brain was greater than extramitochondrial (-c) or intramitochondrial (-m) ...

journal_title：Cell biochemistry and function

authors： Yadav RN

更新日期：1988-07-01 00:00:00

abstract：:The protective effects of carnosine as a natural dipeptide were investigated in mouse bone marrow cells against genotoxicity induced by cyclophosphamide. Mice were injected with solutions of carnosine at three different doses (10, 50 and 100 mg kg(-1) bw) for five consecutive days. On the fifth day of treatment, mice ...

journal_title：Cell biochemistry and function

authors： Naghshvar F,Abianeh SM,Ahmadashrafi S,Hosseinimehr SJ

更新日期：2012-10-01 00:00:00

abstract：:Sexually-transmitted diseases (STD) can facilitate the progression of HIV-1 infection. Among them, as we have previously demonstrated, cervico-vaginal dysplasia-papillomavirus (HPV)-induced, together with HSV-2 co-infection, seems to be correlated with a more evident immunodepression in HIV-positive women, compared wi...

journal_title：Cell biochemistry and function

authors： Pugliese A,Andronico L,Gennero L,Pagliano G,Gallo G,Torre D

更新日期：2002-09-01 00:00:00

abstract：:The use of Nigerian bonny light crude oil (BLCO) in the treatment of gastrointestinal disorders, burns, foot ulcers and reproductive capacity is a common practice in the southern part of Nigeria. Towards understanding the mechanism and the reversibility of hepatotoxicity induced by BLCO, adult male Wistar rats were or...

journal_title：Cell biochemistry and function

authors： Adedara IA,Farombi EO

更新日期：2012-08-01 00:00:00

abstract：:Functional irregularities due to damage after ischaemia-reperfusion vary depending upon the organs affected. High energy phosphates such as ATP and ADP are destroyed after ischaemia-reperfusion damage. Subsequently, protons and inorganic phosphates accumulate within the cells and the proton pumps such as adenosine tri...

journal_title：Cell biochemistry and function

authors： Ilhan N,Halifeoglu I,Ozercan HI,Ilhan N

更新日期：2001-09-01 00:00:00

abstract：:The main purpose of the present investigation was to study the effect of cloturin on aerobic glycolysis, endogenous and exogenous respiration and the level of ATP in both Ehrlich ascites carcinoma (EAC) and P388 murine leukaemia cells incubated in vitro. Also its effect on the level of total (T-SH) and non-protein (NP...

journal_title：Cell biochemistry and function

authors： Miko M,Krepelka J,Melka M

更新日期：1992-06-01 00:00:00