Myricetin ameliorates high glucose-induced endothelial dysfunction in human umbilical vein endothelial cells.

abstract：:Liver-directed gene therapy has become a promising treatment for many liver diseases. In this study, we constructed a multi-functional targeting molecule, which maintains targeting, endosome-escaping, and DNA-binding abilities for gene delivery. Two single oligonucleotide chains of Melittin (M) were synthesized. The f...

journal_title：Cell biochemistry and function

authors： Wang W,Luo J,Xu L,Zeng J,Cao L,Dong J,Cai S

更新日期：2013-12-01 00:00:00

abstract：:Growth factors are biologically-active mediators that bind to specific receptors on target cells and regulate genes involved in cell growth, wound healing and regeneration. In the case of wound healing, a proper wound dressing is needed to cover the wound area, protect the damaged tissue, and if possible to activate c...

journal_title：Cell biochemistry and function

authors： Grdisa M,Popović M,Hrzenjak T

更新日期：2004-11-01 00:00:00

abstract：:Epidermal growth factor plays a major role in breast cancer cell proliferation, survival, and metastasis. Quercetin, a bioactive flavonoid, is shown to exhibit anticarcinogenic effects against various cancers including breast cancer. Hence, the present study was designed to evaluate the effects of gold nanoparticles-c...

journal_title：Cell biochemistry and function

authors： Balakrishnan S,Mukherjee S,Das S,Bhat FA,Raja Singh P,Patra CR,Arunakaran J

更新日期：2017-06-01 00:00:00

abstract：:Reactive oxygen species (ROS) have been implicated in the aetiology of several pathological and degenerative diseases. The protective effect of natural products possessing antioxidant properties has played a crucial role in ameliorating these deleterious effects. This study investigated the chemoprotective properties ...

journal_title：Cell biochemistry and function

authors： Adesanoye OA,Molehin OR,Delima AA,Adefegha AS,Farombi EO

更新日期：2013-10-01 00:00:00

abstract：:Glucocorticoids are important for skeletal muscle energy metabolism, regulating glucose utilization, insulin sensitivity, and muscle mass. Nicotinamide adenine dinucleotide phosphate-dependent 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)-mediated glucocorticoid activation in the sarcoplasmic reticulum (SR) is in...

journal_title：Cell biochemistry and function

authors： Zielinska AE,Fletcher RS,Sherlock M,Doig CL,Lavery GG

更新日期：2017-07-01 00:00:00

abstract：:The effect of citrinin on Ca2+ transport was studied in isolated kidney cortex and liver mitochondria, and baby hamster kidney cultured cells. The mycotoxin significantly inhibited the activity of 2-oxoglutarate and pyruvate dehydrogenases in both kidney cortex and liver mitochondria. Citrinin promoted a decrease in t...

journal_title：Cell biochemistry and function

authors： Chagas GM,Oliveira MA,Campello AP,Kluppel ML

更新日期：1995-03-01 00:00:00

abstract：:Chemotherapeutic drugs that induce DNA damage have the potential to kill cancer cells, but DNA repair protects cells from damage-induced cell death. Thus, eliminating DNA repair is a potential approach to overcome cell drug resistance. In this study, we observed that the gene expression of C-terminal binding protein i...

journal_title：Cell biochemistry and function

authors： Yang L,Yang B,Wang Y,Liu T,He Z,Zhao H,Xie L,Mu H

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Hydrogen peroxide (H(2)O(2)) is a potent reactive oxygen species that causes cardiomyocytes injury. As an important cytokine, interleukin 6 (IL-6) has cardioprotective effects as it plays an essential role in the late phase of preconditioning. Our work is to investigate if IL-6 preconditioning has protective ...

journal_title：Cell biochemistry and function

authors： Jia Y,Zhou F,Deng P,Fan Q,Li C,Liu Y,Fu X,Zhou Y,Xu X,Sun X

更新日期：2012-07-01 00:00:00

abstract：:The aim of this work was to determine the role of intraperitoneally-administered vitamin E and selenium on the biochemical and haematological parameters in the blood of rats. Thirty-two adult male Wistar rats were used in this study. All rats were randomly divided into four groups. The first group was used as the cont...

journal_title：Cell biochemistry and function

authors： Cay M,Naziroğlu M

更新日期：1999-06-01 00:00:00

abstract：:Although techniques for purifying epidermal stem cells (ESCs) have been established, enriching a pure population of viable ESCs is still a challenging task. One approach toward enhancing the purity and viability of ESCs involves cell markers. While evidence suggests that p63 plays a role in maintaining the population ...

journal_title：Cell biochemistry and function

authors： Tao Q,Qiao B,Lv B,Zheng C,Chen Z,Huang H

更新日期：2009-12-01 00:00:00

abstract：:The aim of this brief communication was to determine the correlation between pre-eclampsia (PE), Helicobacter pylori pathogenic strains seropositivity, and interleukin-18 (IL-18) levels. To this purpose 25 pre-eclamptic women and 25 healthy parturient women of similar age were evaluated for: IL-18 levels, by ELISAH. p...

journal_title：Cell biochemistry and function

authors： Pugliese A,Beltramo T,Todros T,Cardaropoli S,Ponzetto A

更新日期：2008-10-01 00:00:00

abstract：:Ras-GTPases regulate many central signalling pathways in the cell. Hypoxia induces nitrosative/oxidative stress and dysregulates Ras-dependent downstream processes. H-Ras possesses two cysteine residues (C181 and C184) in the C-termini, which are palmitoylated once or twice. Palmitoylation is sufficient for promoting ...

journal_title：Cell biochemistry and function

authors： Goloshvili G,Barbakadze T,Mikeladze D

更新日期：2019-10-01 00:00:00

abstract：:The immunological induction of arthritis in the knee of the rabbit is well established as a model for human rheumatoid arthritis. It has the special advantage of allowing the development of the condition, and the effect of disease-modifying agents, to be followed. Attention has been focussed on the activity of glucose...

journal_title：Cell biochemistry and function

authors： Pitsillides AA,Blake SM,Glynn LE,Bitensky L,Chayen J

更新日期：1990-10-01 00:00:00

abstract：:Hyperglycemia induces overproduction of superoxide and it is related to diabetic complications. In this study, we analyzed the antioxidant enzymatic defense and the lipid peroxidation of rat salivary glands in six different periods of diabetic condition. Ninety-six rats were divided into 12 groups: C7/14/21/28/45/60 (...

journal_title：Cell biochemistry and function

authors： Ibuki FK,Simões A,Nogueira FN

更新日期：2010-08-01 00:00:00

abstract：:Voltage-gated Ca(2+) channels regulate cardiac automaticity, rhythmicity and excitation-contraction coupling. Whereas L-type (Cav 1·2, Cav 1·3) and T-type (Cav 3·1, Cav 3·2) channels are widely accepted for their functional relevance in the heart, the role of Cav 2·3 Ca(2+) channels expressing R-type currents remains ...

journal_title：Cell biochemistry and function

authors： Galetin T,Tevoufouet EE,Sandmeyer J,Matthes J,Nguemo F,Hescheler J,Weiergräber M,Schneider T

更新日期：2013-07-01 00:00:00

abstract：:Several studies have highlighted the potential of leucine supplementation for the treatment of metabolic diseases including type 2 diabetes and obesity. Caloric restriction is a common approach to improve the health in diabetic and obese subjects. However, very few studies assessed the effects of leucine supplementati...

journal_title：Cell biochemistry and function

authors： Pedroso JA,Nishimura LS,de Matos-Neto EM,Donato J Jr,Tirapegui J

更新日期：2014-06-01 00:00:00

abstract：:The aim of our study was to evaluate the levels of fibronectin (FN) and its classic receptor (FNR) in various transformed cells lines, especially of leukemic origin, and also the influence of HIV-1 replication on the expression of these proteins (in particular on H9-V cells, chronically infected with HIV-1, and acutel...

journal_title：Cell biochemistry and function

authors： Pugliese A,Comito G,Savarino A,Cantamessa C,Torre D

更新日期：1996-06-01 00:00:00

abstract：:The spreading of HeLa cells on plastic substratum is mediated by fibronectin-depleted foetal calf serum but not by fibronectin isolated by gelatin-Sepharose affinity chromatography. The same is true for freshly explanted chick embryonic chondrocytes. In contrast, BHK cell spreading exceeds 67% after 120 min at 37 degr...

journal_title：Cell biochemistry and function

authors： Michl J,Baudysová M,Sochorová L,Deyl Z

更新日期：1983-07-01 00:00:00

abstract：:Specific binding of a fully biologically active 125I-gonadotrophin releasing hormone (GnRH) to isolated anterior pituitary cells is time dependent, saturable and the concentration dependent binding curves exhibit positive cooperativity. Binding to intact or solubilized plasma membranes and an affinity purified GnRH re...

journal_title：Cell biochemistry and function

authors： Zolman JC,Theodoropoulos TJ

更新日期：1984-10-01 00:00:00

abstract：:Aberrant innate and adaptive immune responsed to allergens and environmental pollutants lead to respiratory allergic disease such as asthma. In this study, we focused on toll-like receptor-4 (TLR4) expressed on airway epithelium to identify house dust mite (HDM)-regulated allergic inflammation via TLR4 signaling pathw...

journal_title：Cell biochemistry and function

authors： Hongjia L,Qingling G,Meiying L,Weixuan W,Lihong Z,Yongsheng G,Yanli L,Jinxiang W,Liang D

更新日期：2010-10-01 00:00:00

abstract：:Regeneration remains a major challenge in skeletal muscle repair after injury. Recently, transforming growth factor-β (TGF-β)/Smad pathway was found to play an important role in inhibiting myogenesis, a crucial stage in skeletal muscle regeneration. In our previous study, microRNA-122-5p (miR-122) was proved to have t...

journal_title：Cell biochemistry and function

authors： Ding Z,Lin J,Sun Y,Cong S,Liu S,Zhang Y,Chen Q,Chen J

更新日期：2020-03-01 00:00:00

abstract：:The aim of the present study is to evaluate the proliferation- and migration-enhancing effects of ginseng and its component, ginsenoside (Rg1) on RSC96 Schwann cells. We investigated the molecular signaling pathways, which include: (1) survival signaling, IGFs-IGFIR-Akt-Bcl2 and proliferative signaling, cell cycle fac...

journal_title：Cell biochemistry and function

authors： Lu MC,Lai TY,Hwang JM,Chen HT,Chang SH,Tsai FJ,Wang HL,Lin CC,Kuo WW,Huang CY

更新日期：2009-06-01 00:00:00

abstract：:Organochalcogens are extensively produced and employed by industry and agriculture, and the risk of occupational and environmental toxicity to them has been poorly understood. Here, we investigated the acute effect of a new organochalcogen 3-methyl-1-phenyl-2-(phenylseleno)oct-2-en-1-one on biochemical and hematologic...

journal_title：Cell biochemistry and function

authors： dos Santos Lacerda D,de Oliveira Castro V,Mascarenhas M,Guerra RB,Dani C,Coitinho A,Gomez R,Funchal C

更新日期：2012-06-01 00:00:00

abstract：:The aim of this study was to investigate the protective effect of ferulic acid at different doses (50 mg kg(-1) alternative day and 50 mg kg(-1) daily) on the streptozotocin (STZ)-induced post-diabetes rat testicular damage. Diabetes was induced by a single intraperitoneal injection of STZ (50 mg/kg). Rats treated wit...

journal_title：Cell biochemistry and function

authors： Roy S,Metya SK,Rahaman N,Sannigrahi S,Ahmed F

更新日期：2014-01-01 00:00:00

abstract：:CYR61 is one of the six proteins of the CCN family of proteins known to play diverse roles in angiogenesis, cellular proliferation, survival, migration and wound healing. However, the specific function of CYR61 in cancer is unclear, and the literature remains controversial. We used quantitative real-time PCR to establ...

journal_title：Cell biochemistry and function

authors： Jandova J,Beyer TE,Meuillet EJ,Watts GS

更新日期：2012-12-01 00:00:00

abstract：:Current studies have shown that circular RNAs (circRNAs) and microRNAs (miRNAs) are closely related in acute myocardial infarction (AMI). Previous studies have shown that miR-125b promotes fibrosis and up-regulates in cardiac fibroblasts (CFs), and further experiments showed that circ_LAS1L had multiple binding sites ...

journal_title：Cell biochemistry and function

authors： Sun LY,Zhao JC,Ge XM,Zhang H,Wang CM,Bie ZD

更新日期：2020-06-01 00:00:00

abstract：:Development and homeostasis of multicellular organisms require interactions between neighbouring cells. We recently established an in vitro model of cell-cell interaction based on a collagen vitrigel membrane. We have now examined the role of neural cells in retinal homeostasis by coculture of human retinal pigment ep...

journal_title：Cell biochemistry and function

authors： Ko JA,Hirata J,Yamane K,Sonoda KH,Kiuchi Y

更新日期：2015-01-01 00:00:00

abstract：:Involvement of complications is considered to be one of the major factors in the prognosis of diabetes mellitus (DM). Recent studies indicate that most diabetic complications such as nephropathy and hypertension are vascular-originated. Renin-angiotensin involvement, especially changes in ACE activity level, is consid...

journal_title：Cell biochemistry and function

authors： Ustündağ B,Canatan H,Cinkilinç N,Halifeoğlu I,Bahçecioğlu IH

更新日期：2000-03-01 00:00:00

abstract：:Bronchopulmonary dysplasia (BPD) is a common complication of premature birth that seriously affects the survival rate and quality of life among preterm neonates. Long non-coding RNAs (lncRNAs) have been implicated in many human diseases. However, the role of lncRNAs in the pathogenesis of BPD remains poorly understood...

journal_title：Cell biochemistry and function

authors： Bao TP,Wu R,Cheng HP,Cui XW,Tian ZF

更新日期：2016-07-01 00:00:00

abstract：:Mitochondrial, endoplasmic reticular and plasma membrane fractions were isolated by a new method from control male Fischer 344 rats and rats given CCl4 by gavage. After 1 h of CCl4 treatment, rats were in glucose and pancreatic hormone balance but plasma levels of T3 and T4 were decreased 29 and 22%, respectively. Aft...

journal_title：Cell biochemistry and function

authors： Hemmings SJ,Pulga VB,Tran ST,Uwiera RR

更新日期：2002-03-01 00:00:00