miR-122-5p negatively regulates the transforming growth factor-β/Smad signaling pathway in skeletal muscle myogenesis.

abstract：:The modification of myeloperoxidase and lactoperoxidase with 2-(O-methoxypolethylene glycol)-4, 6-dichloro-s-triazine, an activated polyethylene glycol (PEG1), was investigated. The modification caused a shift of the Soret band in the light absorption spectrum, from 430 nm to 418 nm in the case of myeloperoxidase (nat...

journal_title：Cell biochemistry and function

authors： Odajima T,Onishi M

更新日期：1998-06-01 00:00:00

abstract：:Prostate cancer metastasis is often associated with poor prognosis. The molecular coupling of the adaptor protein Crk to the docking protein p130(Cas) serves as a switch that regulates cell migration in several invasive cancer cells and Ack appears to act upstream of CrkII to modulate the cell motility. However, the p...

journal_title：Cell biochemistry and function

authors： Dai Y,Qi L,Zhang X,Li Y,Chen M,Zu X

更新日期：2011-12-01 00:00:00

abstract：:The study aims to evaluate the effect of saxagliptin, a specific inhibitor of dipeptidyl peptidase-4 enzymes, on body weight gain, lipid profiles, and cell death through apoptosis in rats with insulin resistance (IR). Male adult Sprague-Dawley rats (n = 32) were divided into 4 groups: control (Ctrl), IR, saxagliptin c...

journal_title：Cell biochemistry and function

authors： Nephan G,Coskun ZM,Bolkent S

更新日期：2018-06-01 00:00:00

abstract：:The p53 protein plays a critical role in suppression of tumour growth; its regulation is not fully understood. Leukaemia/lymphoma-related factor (LRF) promotes tumour cell growth. This study tests a hypothesis that LRF inhibits p53 expression in colon cancer cells. In this study, human colon cancer cell lines, LIM1215...

journal_title：Cell biochemistry and function

authors： Zhu M,Wang P,Feng F,Li MY

更新日期：2017-10-01 00:00:00

abstract：:Organochalcogens are extensively produced and employed by industry and agriculture, and the risk of occupational and environmental toxicity to them has been poorly understood. Here, we investigated the acute effect of a new organochalcogen 3-methyl-1-phenyl-2-(phenylseleno)oct-2-en-1-one on biochemical and hematologic...

journal_title：Cell biochemistry and function

authors： dos Santos Lacerda D,de Oliveira Castro V,Mascarenhas M,Guerra RB,Dani C,Coitinho A,Gomez R,Funchal C

更新日期：2012-06-01 00:00:00

abstract：:Recent studies have demonstrated that germ-like cells could be differentiated from human umbilical cord mesenchymal stem cells (hUC-MSCs) in vitro. Whether the sexuality of hUC-MSCs affects the formation efficiency of germ-like cells derived from hUC-MSCs is still unclear. To clearly test the formation efficiency of o...

journal_title：Cell biochemistry and function

authors： Qiu P,Bai Y,Pan S,Li W,Liu W,Hua J

更新日期：2013-07-01 00:00:00

abstract：:Because elevated oxidative stress may exacerbate cardiovascular complications of diabetes mellitus, the current study aimed to investigate the effects of treatment with either vitamin A, an antioxidant, or with insulin on lipid peroxidation products and antioxidant enzyme activities of diabetic rat heart. Also to eval...

journal_title：Cell biochemistry and function

authors： Zobali F,Avci A,Canbolat O,Karasu C

更新日期：2002-06-01 00:00:00

abstract：:A method for the quantification of energy consuming processes described by Siems et al. for reticulocytes and by Müller et al. for ascites tumour cells was applied to balance the ATP-consumption of isolated rat hepatocytes. On the basis of decreased coupled respiration rates following the specific inhibition of energy...

journal_title：Cell biochemistry and function

authors： Schneider W,Siems W,Grune T

更新日期：1990-10-01 00:00:00

abstract：:Renal cell carcinoma (RCC) is the most common renal tumour in adults. Altered levels of secondary messengers, that is, intracellular calcium and cyclic AMP (cAMP), have been implicated in the pathogenesis of various malignancies. In the present study, we measured levels of intracellular calcium and cAMP in RCC. The in...

journal_title：Cell biochemistry and function

authors： Sharma U,Singh SK,Rajendra P

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Hydrogen peroxide (H(2)O(2)) is a potent reactive oxygen species that causes cardiomyocytes injury. As an important cytokine, interleukin 6 (IL-6) has cardioprotective effects as it plays an essential role in the late phase of preconditioning. Our work is to investigate if IL-6 preconditioning has protective ...

journal_title：Cell biochemistry and function

authors： Jia Y,Zhou F,Deng P,Fan Q,Li C,Liu Y,Fu X,Zhou Y,Xu X,Sun X

更新日期：2012-07-01 00:00:00

abstract：:Nuclear, chromatin and microsomal fractions were isolated from hepatocytes prepared from rats injected with [32P]O4(2-) and killed subsequently at times between 1 and 48 h. Specific activities of the total phospholipids (PL) were determined for each subcellular fraction. The major points noted were the initial specifi...

journal_title：Cell biochemistry and function

authors： Viola-Magni MP,Gahan PB,Albi E,Iapoce R,Gentilucci PF

更新日期：1986-10-01 00:00:00

abstract：:Differences in metabolism of drugs can lead to severe toxicity or therapeutic failure. In addition to cytochrome P450 2D6, which plays a critical role in drug metabolism, ABCB1 encoded P-glycoprotein (PGP) is also an important determinant in drug bioavailability. The genes encoding these molecules are highly variable ...

journal_title：Cell biochemistry and function

authors： Correia C,Santos P,Coutinho AM,Vicente AM

更新日期：2009-06-01 00:00:00

abstract：:Thyroid hormones regulate energy metabolism and act on mitochondria which are an important source of free radicals in the cell. The pineal gland activates antioxidant systems via melatonin secretion and thus has a protective function in body tissues. The present study was conducted to determine the oxidative damage ca...

journal_title：Cell biochemistry and function

authors： Mogulkoc R,Baltaci AK,Aydin L,Oztekin E,Tuncer I

更新日期：2006-09-01 00:00:00

abstract：:Reactive oxygen metabolites play an important role in ischemia-reperfusion related gastric injury. Primary sources of reactive oxygen metabolites seem to be the xanthine/xanthine oxidase system and neutrophils accumulating within the reperfused tissue. Tissue myeloperoxidase activity is an important index of neutrophi...

journal_title：Cell biochemistry and function

authors： Derin N,Agac A,Bayram Z,Asar M,Izgut-Uysal VN

更新日期：2006-09-01 00:00:00

abstract：:Analysis of free nucleotide composition of both avian thrombocytes and pig platelets showed quantitative differences in the level of adenine nucleotides. 3H-adenine taken up by turkey thrombocytes was metabolized mainly to adenine nucleotides was not released after thrombin action. Thrombin liberated non-radioactive a...

journal_title：Cell biochemistry and function

authors： Wachowicz B

更新日期：1984-07-01 00:00:00

abstract：:The biochemical and quantitative cytochemical assays of the activity of uridine diphosphoglucose dehydrogenase (UDPG-D) have produced perplexing results. It is now shown that the perplexity may be due to the possibility that the coenzyme (NAD) required for UDPG-D activity, may be acting as a substrate for a second deh...

journal_title：Cell biochemistry and function

authors： Mehdizadeh S,Bitensky L,Chayen J

更新日期：1991-04-01 00:00:00

abstract：:Using several physical techniques the surface of articular cartilage has been reported to be structurally different from the deeper layers. In this paper using immunohistochemical methods, the surface has been shown to contain a characteristically different collagen, Type I in contrast to Type II which is the major co...

journal_title：Cell biochemistry and function

authors： Duance VC

更新日期：1983-10-01 00:00:00

abstract：:Sprouty1 protein belongs to a family of receptor tyrosine kinase-mediated signaling inhibitors, whose members are usually regulated by growth factors to form a negative feedback loop. Correspondingly fluctuations of Sprouty1 mRNA in response to single growth factors have been observed. In this report, we investigate S...

journal_title：Cell biochemistry and function

authors： Kral RM,Mayer CE,Vanas V,Gsur A,Sutterlüty-Fall H

更新日期：2014-01-01 00:00:00

abstract：:Cyclophosphamide (CP) has potential urotoxicity such as hemorrhagic cystitis (HC). 2-Mercaptoethane sulfonate (mesna) has been widely used as an effective agent against CP-induced cystitis, but significant HC has still been encountered clinically. In recent studies, mesna was shown to be more effective if combined wit...

journal_title：Cell biochemistry and function

authors： Sadir S,Deveci S,Korkmaz A,Oter S

更新日期：2007-09-01 00:00:00

abstract：:Diabetes is associated with increased reactivity of the renal vascular bed to endothelin-1 (ET-1). It has been observed that diabetes is associated with over-expression of ET(A)- and ET(B)-receptors in the rat renal cortex. However it is not known if these receptors are over-expressed in the renal artery. The objectiv...

journal_title：Cell biochemistry and function

authors： Yousif MH

更新日期：2006-09-01 00:00:00

abstract：:The aim of this brief communication was to determine the correlation between pre-eclampsia (PE), Helicobacter pylori pathogenic strains seropositivity, and interleukin-18 (IL-18) levels. To this purpose 25 pre-eclamptic women and 25 healthy parturient women of similar age were evaluated for: IL-18 levels, by ELISAH. p...

journal_title：Cell biochemistry and function

authors： Pugliese A,Beltramo T,Todros T,Cardaropoli S,Ponzetto A

更新日期：2008-10-01 00:00:00

abstract：:Silibinin, an effective anti-cancer and chemopreventive agent in various epithelial cancer models, has been reported to inhibit cancer cell growth through mitogenic signalling pathways including cervical cancer. However, the underlying mechanisms are still not well elucidated. Here, we assessed the effect of silibinin...

journal_title：Cell biochemistry and function

authors： Zhang Y,Ge Y,Chen Y,Li Q,Chen J,Dong Y,Shi W

更新日期：2012-04-01 00:00:00

abstract：:Dietary soy lecithin supplementation decreases hyperlipidemia and influences lipid metabolism. Although this product is used by diabetic patients, there are no data about the effect of soy lecithin supplementation on the immune system. The addition of phosphatidylcholine, the main component of lecithin, to a culture o...

journal_title：Cell biochemistry and function

authors： Miranda DT,Batista VG,Grando FC,Paula FM,Felício CA,Rubbo GF,Fernandes LC,Curi R,Nishiyama A

更新日期：2008-12-01 00:00:00

abstract：:Bronchopulmonary dysplasia (BPD) is a common complication of premature birth that seriously affects the survival rate and quality of life among preterm neonates. Long non-coding RNAs (lncRNAs) have been implicated in many human diseases. However, the role of lncRNAs in the pathogenesis of BPD remains poorly understood...

journal_title：Cell biochemistry and function

authors： Bao TP,Wu R,Cheng HP,Cui XW,Tian ZF

更新日期：2016-07-01 00:00:00

abstract：:The gene expression of heme oxygenase-1 (HO-1) was studied in mammalian cell lines exposed to hyperoxia. Northern blot analysis demonstrated that hyperoxic exposure increased the HO-1 mRNA levels in various types of cells, including human hepatoma (HepG2) cells. This increase was time- and dose-dependent, and reversib...

journal_title：Cell biochemistry and function

authors： Takahashi S,Takahashi Y,Yoshimi T,Miura T

更新日期：1998-09-01 00:00:00

abstract：:In murine thymocytes cyclic nucleotide phosphodiesterase is represented by cAMP- and cGMP-specific forms. cAMP and cGMP phosphodiesterase activities showed anomalous kinetic behaviour indicative of 'low' and 'high' affinity enzyme forms. Sucrose density gradient centrifugation resolved only 'low' affinity forms of cAM...

journal_title：Cell biochemistry and function

authors： Sobolev AS,Rybalkin SD

更新日期：1986-07-01 00:00:00

abstract：:In this study, the antimicrobial effects of monophosphazenes such as SM ipemphos and amphos were examined on bacterial and yeast strains. In addition, the biological effects of these compounds were tested on the lipid level of Saccharomyces cerevisiae and Candida albicans cells. The SM has an antimicrobial effect on t...

journal_title：Cell biochemistry and function

authors： Oztürk AI,Yilmaz O,Kirbağ S,Arslan M

更新日期：2000-06-01 00:00:00

abstract：:Rat liver nonparenchymal cells (NPC) were prepared by pronase digestion and purified on discontinuous gradients on Nycodenz. Morphological and biochemical characterization of cell suspensions showed that they were free of contamination by hepatocytes. We have confirmed the usefulness of pyruvate kinase activity in mon...

journal_title：Cell biochemistry and function

authors： Rich K,Lodola A

更新日期：1989-10-01 00:00:00

abstract：:Mast cells are widely distributed in the body and affect their surrounding environment through degranulation and secretion of cytokines. Conversely, mast cells are influenced by environmental stimuli such as cyclical mechanical stretch (CMS), such as that induced by heartbeat and respiration. Peripherally distributed ...

journal_title：Cell biochemistry and function

authors： Komiyama H,Miyake K,Asai K,Mizuno K,Shimada T

更新日期：2014-01-01 00:00:00

abstract：:The use of Nigerian bonny light crude oil (BLCO) in the treatment of gastrointestinal disorders, burns, foot ulcers and reproductive capacity is a common practice in the southern part of Nigeria. Towards understanding the mechanism and the reversibility of hepatotoxicity induced by BLCO, adult male Wistar rats were or...

journal_title：Cell biochemistry and function

authors： Adedara IA,Farombi EO

更新日期：2012-08-01 00:00:00