Inverse correlation of intracellular calcium and cyclic AMP levels in renal cell carcinoma.

Abstract:

:Renal cell carcinoma (RCC) is the most common renal tumour in adults. Altered levels of secondary messengers, that is, intracellular calcium and cyclic AMP (cAMP), have been implicated in the pathogenesis of various malignancies. In the present study, we measured levels of intracellular calcium and cAMP in RCC. The intracellular calcium level was significantly reduced, whereas the cAMP level was significantly augmented in RCC as compared with adjacent grossly normal renal parenchyma.

journal_name

Cell Biochem Funct

authors

Sharma U,Singh SK,Rajendra P

doi

10.1002/cbf.2913

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

619-22

issue

8

eissn

0263-6484

issn

1099-0844

journal_volume

30

pub_type

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