Effect of serotonin-acting agents on the serotonin content of immune cells. A peculiar observation.

abstract：:The phospholipid profiles of the myocardium (from 10- and 18-day old chick embryos and 13-day old chick) and their in vitro response to the endogenous lipolytic enzymes (mainly of the phospholipase group) at pH 7.4 and 38 degrees C for 60 min were analyzed by TLC technology and densitometry. Cardiolipin (CL) was shown...

journal_title：Cell biochemistry and function

authors： Helmy FM,Aikins A,Hughes J,Belfield C,Juracka A

更新日期：2007-09-01 00:00:00

abstract：:Corneal scarring is the result of a disease, infection or injury. The resulting scars cause significant loss of vision or even blindness. To-date, the most successful treatment is corneal transplantation, but it does not come without side effects. One of the corneal dystrophies that are correlated with corneal scarrin...

journal_title：Cell biochemistry and function

authors： McKay TB,Sarker-Nag A,Lyon D,Asara JM,Karamichos D

更新日期：2015-07-01 00:00:00

abstract：:Cyclophilin A (Cyp A), a member of the peptidyl-prolyl isomerase (PPI) family, may function as a molecular signalling switch. Comparative proteomic studies have identified Cyp A as a potential downstream target of protein kinase B (Akt). This study confirmed that Cyp A is a downstream effector of the phosphatidylinosi...

journal_title：Cell biochemistry and function

authors： Lin ZL,Wu HJ,Chen JA,Lin KC,Hsu JH

更新日期：2015-12-01 00:00:00

abstract：:Metabolism of arabinose 5-P, ribose 5-P and glucose 6-P in permeabilized and resealed Morris hepatoma 5123TC cells was investigated by measuring the contribution of these compounds to nucleic acid biosynthesis. The level of [14C]-arabinose (non-phosphorylated) incorporation into nucleic acids was slight, presumably du...

journal_title：Cell biochemistry and function

authors： Arora KK,Williams JF

更新日期：1987-10-01 00:00:00

abstract：:Involvement of complications is considered to be one of the major factors in the prognosis of diabetes mellitus (DM). Recent studies indicate that most diabetic complications such as nephropathy and hypertension are vascular-originated. Renin-angiotensin involvement, especially changes in ACE activity level, is consid...

journal_title：Cell biochemistry and function

authors： Ustündağ B,Canatan H,Cinkilinç N,Halifeoğlu I,Bahçecioğlu IH

更新日期：2000-03-01 00:00:00

abstract：:The protective effects of betaine in ethanol hepatotoxicity were investigated in 24 female wistar albino rats. Animals were divided into three groups: control, ethanol and ethanol + betaine group. Animals were fed liquid diets and consumed approximately 60 diet per day. Rats were fed ethanol 8 kg(- 1) day(- 1). The et...

journal_title：Cell biochemistry and function

authors： Kanbak G,Inal M,Bayçu C

更新日期：2001-12-01 00:00:00

abstract：:Liver-directed gene therapy has become a promising treatment for many liver diseases. In this study, we constructed a multi-functional targeting molecule, which maintains targeting, endosome-escaping, and DNA-binding abilities for gene delivery. Two single oligonucleotide chains of Melittin (M) were synthesized. The f...

journal_title：Cell biochemistry and function

authors： Wang W,Luo J,Xu L,Zeng J,Cao L,Dong J,Cai S

更新日期：2013-12-01 00:00:00

abstract：:MicroRNA (miRNAs) are short non-coding RNA molecules that downregulate gene expression at post-transcriptional level. miRNAs are post-transcriptional regulators of gene expression important for neuron development and function. This report demonstrated that a putative and chemically synthesized miRNA rno-mir-541 played...

journal_title：Cell biochemistry and function

authors： Zhang J,Zhang J,Liu LH,Zhou Y,Li YP,Shao ZH,Wu YJ,Li MJ,Fan YY,Shi HJ

更新日期：2011-06-01 00:00:00

abstract：:Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer, and thymidine phosphorylase (TP) is a regulator of angiogenesis. To investigate the biological activities of TP in ICC, we established human cholangiocarcinoma RBE cell lines overexpressing TP or silencing TP. Overexpression of TP en...

journal_title：Cell biochemistry and function

authors： Li S,Yang H,Li K,Fan G,Deng L,Xu C

更新日期：2020-08-01 00:00:00

abstract：:Glaucoma is optic neuropathy that is characterized by progressive neurodegeneration of the retinal ganglion cells (RGCs) and axons. This condition will lead to visual impairment and bring glaucoma to become the second cause of blindness globally. Neuroprotection in glaucoma is needed to prevent the progression of opti...

journal_title：Cell biochemistry and function

authors： Ko JA,Komatsu K,Okumichi H,Kiuchi Y

更新日期：2021-01-01 00:00:00

abstract：:Lipopolysaccharide (LPS)-induced inflammatory factors production by the cerebral cortical glial cells in two sides of the murine brain are different. To determine if microglial cells, a subset of glial cells, are involved in asymmetric production, interleukin-6 (IL-6), interleukin-1β (IL-1β) and nitric oxide (NO) resp...

journal_title：Cell biochemistry and function

authors： Xin G,Su Y,Gao YL,Zhang H,Wang GF,Li KS

更新日期：2011-01-01 00:00:00

abstract：:Reactive oxygen species (ROS) have been implicated in the aetiology of several pathological and degenerative diseases. The protective effect of natural products possessing antioxidant properties has played a crucial role in ameliorating these deleterious effects. This study investigated the chemoprotective properties ...

journal_title：Cell biochemistry and function

authors： Adesanoye OA,Molehin OR,Delima AA,Adefegha AS,Farombi EO

更新日期：2013-10-01 00:00:00

abstract：:In pancreatic islets prepared from fed rats and incubated at a low concentration (1.7 mM) of D-glucose, D-mannoheptulose (10.0 mM) virtually fails to affect the metabolism of the hexose. Likewise, in islets from starved rats, the relative extent of the inhibitory action of D-mannoheptulose upon D-glucose metabolism is...

journal_title：Cell biochemistry and function

authors： Picton S,Malaisse WJ

更新日期：1999-03-01 00:00:00

abstract：:The consumption of protein supplements containing amino acids is increasing around the world. Aspartate (Asp) and asparagine (Asn) are amino acids metabolized by skeletal muscle. This metabolism involves biochemical pathways that are involved in increasing Krebs cycle activity via anaplerotic reactions, resulting in h...

journal_title：Cell biochemistry and function

authors： Lancha AH Jr,Poortmans JR,Pereira LO

更新日期：2009-12-01 00:00:00

abstract：:This study was designed to investigate the role of HO-1 induction in prevention of thioacetamide (TAA)-induced oxidative stress, inflammation and liver damage. The changes in hepatic dimethylarginine dimethylaminohydrolase (DDAH) activity as well as plasma arginine and asymmetric dimethylarginine (ADMA) levels were al...

journal_title：Cell biochemistry and function

authors： Develi-Is S,Bekpinar S,Kalaz EB,Evran B,Unlucerci Y,Gulluoglu M,Uysal M

更新日期：2013-03-01 00:00:00

abstract：:Systemic sclerosis (SSc) is an autoimmune disease characterized by inflammation and fibrosis of the skin and visceral organs. Fibrosis associated with SSc is characterized by an increased synthesis of a wide range of extracellular matrix (ECM). TGF-beta is a pluripotent cytokine in a wide range of cell types. In parti...

journal_title：Cell biochemistry and function

authors： Büyük U,Ates O,Dalyan L,Müsellim B,Ongen G,Topal-Sarikaya A

更新日期：2010-06-01 00:00:00

abstract：:Nuclear, chromatin and microsomal fractions were isolated from hepatocytes prepared from rats injected with [32P]O4(2-) and killed subsequently at times between 1 and 48 h. Specific activities of the total phospholipids (PL) were determined for each subcellular fraction. The major points noted were the initial specifi...

journal_title：Cell biochemistry and function

authors： Viola-Magni MP,Gahan PB,Albi E,Iapoce R,Gentilucci PF

更新日期：1986-10-01 00:00:00

abstract：:Research on prostate cancer progression has focused extensively on the concept of miRNA, which can operate either as promoters or as suppressors of carcinogenesis. Moreover, recent genetic studies and emerging functional work show that strikingly similar and overlapping pathways are involved in prostate carcinogenesis...

journal_title：Cell biochemistry and function

authors： Farooqi AA,Naqi A,Qureshi MZ,Rana A,Khan A,Riaz AM,Afzal SM,Rasheed N,Bhatti S

更新日期：2012-10-01 00:00:00

abstract：:Gastrin-releasing peptide (GRP) receptors are present in pancreatic islets, though their regulation is unknown except for homologous desensitization. The modulation of binding of GRP to mouse pancreatic islets and INS-1 cells was studied. At 60 min (steady-state), total binding of [(125)I-Tyr(15)] GRP was 1.62 per cen...

journal_title：Cell biochemistry and function

authors： Kloss H,Wahl MA,Neye H,Verspohl EJ

更新日期：1999-12-01 00:00:00

abstract：:Hyperglycemia induces overproduction of superoxide and it is related to diabetic complications. In this study, we analyzed the antioxidant enzymatic defense and the lipid peroxidation of rat salivary glands in six different periods of diabetic condition. Ninety-six rats were divided into 12 groups: C7/14/21/28/45/60 (...

journal_title：Cell biochemistry and function

authors： Ibuki FK,Simões A,Nogueira FN

更新日期：2010-08-01 00:00:00

abstract：:The aim of this study was to evaluate the role of mitochondria in the recovery of cardiac energetics induced by ischaemic preconditioning at reperfusion. Isolated rat hearts were aerobically perfused (control), subjected to global ischaemia and reperfusion (reperfusion), or subjected to 3 brief cycles of ischaemia/rep...

journal_title：Cell biochemistry and function

authors： Muscari C,Bonafè F,Gamberini C,Giordano E,Lenaz G,Caldarera CM

更新日期：2006-11-01 00:00:00

abstract：:The objectives of study were (a) to determine alteration of feeding, glucose level and oxidative stress and (b) to investigate expression and localization of cannabinoid receptors in type-2 diabetic rat pancreas treated with Δ(9)-tetrahydrocannabinol (Δ(9)-THC). Rats were randomly divided into four groups: control, Δ(...

journal_title：Cell biochemistry and function

authors： Coskun ZM,Bolkent S

更新日期：2014-10-01 00:00:00

abstract：:Mitochondrial proton leak can account for almost 20% of oxygen consumption and it is generally accepted that this process contributes to basal metabolism. In order to clarify the role of basal proton leak in testicular mitochondria, we performed a comparative study with kidney and liver mitochondrial fractions. Proton...

journal_title：Cell biochemistry and function

authors： Rodrigues AS,Lacerda B,Moreno AJ,Ramalho-Santos J

更新日期：2010-04-01 00:00:00

abstract：:Deficiency in neutrophils (neutropenia) caused by mutations in neutrophil elastase (NE, ELA2) has been extensively investigated. Monocytes and neutrophils are derived from a common myeloid progenitor; therefore, ELA2 mutations can also influence monocyte development. These effects have not been well described. In this...

journal_title：Cell biochemistry and function

authors： Lee HH,Sung MH

更新日期：2013-06-01 00:00:00

abstract：:Psoriasis is a common chronic and recurrent inflammatory skin disease with unknown etiology that has been associated with abnormal plasma lipid metabolism and oxidative stress. There are controversial results in the previous studies investigating oxidant/antioxidant systems in psoriasis.The aim of this work was to eva...

journal_title：Cell biochemistry and function

authors： Toker A,Kadi M,Yildirim AK,Aksoy H,Akçay F

更新日期：2009-04-01 00:00:00

abstract：:Sonic hedgehog (Shh) plays important roles in developmental of vertebrate animal central nervous system (CNS), and Gli is its downstream signal molecule. Shh signalling is essential for pattern formation, cell-fate specification, axon guidance, proliferation, survival and differentiation of neurons in CNS development....

journal_title：Cell biochemistry and function

authors： Li X,Li Y,Li S,Li H,Yang C,Lin J

更新日期：2020-08-25 00:00:00

abstract：:We investigated the effect of rosiglitazone (RSG), a high-affinity ligand for the peroxisome proliferator-activated receptor gamma which mediates insulin-sensitizing actions, on the lipid profile and oxidative status in streptozotocin (STZ)-induced Type 2 diabetes mellitus (DM) rats. Wistar albino male rats were rando...

journal_title：Cell biochemistry and function

authors： Kavak S,Ayaz L,Emre M,Inal T,Tamer L,Günay I

更新日期：2008-06-01 00:00:00

abstract：:The aim of this work was to determine the role of intraperitoneally-administered vitamin E and selenium on the biochemical and haematological parameters in the blood of rats. Thirty-two adult male Wistar rats were used in this study. All rats were randomly divided into four groups. The first group was used as the cont...

journal_title：Cell biochemistry and function

authors： Cay M,Naziroğlu M

更新日期：1999-06-01 00:00:00

abstract：:The number of reports on the effects induced by electromagnetic radiation (EMR) in various cellular systems is still increasing. Until now no satisfactory mechanism has been proposed to explain the biological effects of this radiation. Oxygen free radicals may play a role in mechanisms of adverse effects of EMR. This ...

journal_title：Cell biochemistry and function

authors： Irmak MK,Fadillioğlu E,Güleç M,Erdoğan H,Yağmurca M,Akyol O

更新日期：2002-12-01 00:00:00

abstract：:The influence of the 1,4-dihydropyridines (DHPs), water-soluble glutapyrone available as sodium, potassium and ammonium salts of 2-(2,6-dimethyl-3,5-diethoxycarbonyl-1,4-DHP-4-carboxamide)glutaric acid, from one side, and a lipophylic cerebrocrast, 2-propoxyethyl 2,6-dimethyl-4-(2-difluoromethoxyphenyl)-1,4-DHP-3,5-di...

journal_title：Cell biochemistry and function

authors： Velena A,Skujiņs A,Svirskis S,Bisenieks E,Uldriķis J,Poikans J,Duburs G,Klusa V

更新日期：1997-09-01 00:00:00