Quercetin modulates keratoconus metabolism in vitro.

abstract：:The aim of this study was to evaluate the role of mitochondria in the recovery of cardiac energetics induced by ischaemic preconditioning at reperfusion. Isolated rat hearts were aerobically perfused (control), subjected to global ischaemia and reperfusion (reperfusion), or subjected to 3 brief cycles of ischaemia/rep...

journal_title：Cell biochemistry and function

authors： Muscari C,Bonafè F,Gamberini C,Giordano E,Lenaz G,Caldarera CM

更新日期：2006-11-01 00:00:00

abstract：:The erythrocytes of mammals represent a good model to evaluate the cytotoxicity of molecules, organic and inorganic, natural or synthetic, by cellular damage measure. Indeed, before any investigation on the mechanism of action of different molecules, it is important to perform a cytotoxicity assay. Among the different...

journal_title：Cell biochemistry and function

authors： Pagano M,Faggio C

更新日期：2015-08-01 00:00:00

abstract：:The new glass ionomer dental cement, ChemFil, was found to be moderately cytotoxic when freshly mixed in vitro. This was assessed by a reduction in fibroblast and macrophage counts following 24 h exposure to the material, and by alterations in enzyme levels and enzyme staining kinetics relative to control cultures. Te...

journal_title：Cell biochemistry and function

authors： Meryon SD,Browne RM

更新日期：1984-01-01 00:00:00

abstract：:In murine thymocytes cyclic nucleotide phosphodiesterase is represented by cAMP- and cGMP-specific forms. cAMP and cGMP phosphodiesterase activities showed anomalous kinetic behaviour indicative of 'low' and 'high' affinity enzyme forms. Sucrose density gradient centrifugation resolved only 'low' affinity forms of cAM...

journal_title：Cell biochemistry and function

authors： Sobolev AS,Rybalkin SD

更新日期：1986-07-01 00:00:00

abstract：:The heart responds to an increased demand arising due to physiological stimuli or pathological insults by hypertrophy of myocytes. Reactive oxygen species (ROS) have recently been identified as the molecular intermediates in the translation of mechanical stimuli to cellular response. Different signal transduction path...

journal_title：Cell biochemistry and function

authors： Adiga IK,Nair RR

更新日期：2008-04-01 00:00:00

abstract：:Familial Mediterranean Fever (FMF) is an autosomal recessive hereditary disease leading mostly to renal failure and nephrotic syndrome. The ultrastructure of kidney has not been fully investigated in FMF associated renal disease. The aim of this study is to provide further evidence on the ultrastructure of kidney in p...

journal_title：Cell biochemistry and function

authors： Kiliçaslan SM,Ayvali C,Taştan H

更新日期：2007-07-01 00:00:00

abstract：:Endometrial cancer (EC) is the most common gynaecologic malignancy in western countries and has been reported to account for about 7% of female malignant tumours and 20% to 30% of female genital system malignant tumours. Accumulating evidence showed the expression of human trophoblast cell surface antigen 2 (Trop2) wa...

journal_title：Cell biochemistry and function

authors： Sun X,Xing G,Zhang C,Lu K,Wang Y,He X

更新日期：2020-03-01 00:00:00

abstract：:A previous study showing that ethanol (ETOH) blocked [3H]choline incorporation into phosphatidylcholine (PC) suggested an inhibition of PC biosynthesis in human leukemic monocyte-like U937 cells. The mechanism of the inhibitory action of ETOH was investigated. Cells were pulsed with [3H]choline for 30 min and chased i...

journal_title：Cell biochemistry and function

authors： Chu AJ

更新日期：1994-01-01 00:00:00

abstract：:Silibinin, an effective anti-cancer and chemopreventive agent in various epithelial cancer models, has been reported to inhibit cancer cell growth through mitogenic signalling pathways including cervical cancer. However, the underlying mechanisms are still not well elucidated. Here, we assessed the effect of silibinin...

journal_title：Cell biochemistry and function

authors： Zhang Y,Ge Y,Chen Y,Li Q,Chen J,Dong Y,Shi W

更新日期：2012-04-01 00:00:00

abstract：:CYR61 is one of the six proteins of the CCN family of proteins known to play diverse roles in angiogenesis, cellular proliferation, survival, migration and wound healing. However, the specific function of CYR61 in cancer is unclear, and the literature remains controversial. We used quantitative real-time PCR to establ...

journal_title：Cell biochemistry and function

authors： Jandova J,Beyer TE,Meuillet EJ,Watts GS

更新日期：2012-12-01 00:00:00

abstract：:Ceramide is known to trigger apoptosis of nucleated cells and eryptosis of erythrocytes. Eryptosis is characterized by cell shrinkage and cell membrane scrambling with phosphatidylserine translocation to the erythrocyte surface. Besides ceramide, stimulators of eryptosis include increase of cytosolic Ca(2+) -activity ...

journal_title：Cell biochemistry and function

authors： Signoretto E,Zierle J,Bhuyan AA,Castagna M,Lang F

更新日期：2016-07-01 00:00:00

abstract：:The study of the influence of the age of the animals (13 to 53 weeks) on the rate of ethanol metabolism in vivo and the total activity of liver alcohol dehydrogenase and microsomal ethanol oxidizing system showed a progressive decline with age. These effects were observed concomitantly with a diminution in the content...

journal_title：Cell biochemistry and function

authors： Fernandez V,Kriz A,Videla LA

更新日期：1988-01-01 00:00:00

abstract：:Uptake of polyamines has been investigated extensively in many cells, but not in placenta, where the polyamine-polyamine oxidase system is supposed to have an immunoregulatory function in pregnancy. Due to the importance of the transfer in this tissue, we have started this study. JAR human placental choriocarcinoma ce...

journal_title：Cell biochemistry and function

authors： Fontana L,Cravanzola C,Colombatto S,Grillo MA

更新日期：1996-09-01 00:00:00

abstract：:Although techniques for purifying epidermal stem cells (ESCs) have been established, enriching a pure population of viable ESCs is still a challenging task. One approach toward enhancing the purity and viability of ESCs involves cell markers. While evidence suggests that p63 plays a role in maintaining the population ...

journal_title：Cell biochemistry and function

authors： Tao Q,Qiao B,Lv B,Zheng C,Chen Z,Huang H

更新日期：2009-12-01 00:00:00

abstract：:The effects of 1,25-dihydroxyvitamin D3 are mediated by binding to a specific intracellular vitamin D receptor (VDR), which has been identified in a variety of tissues. Certain polymorphisms in the VDR gene have been associated with various neoplasms. For this purpose, we studied whether VDR TaqI or FokI genotype are ...

journal_title：Cell biochemistry and function

authors： Yaylim-Eraltan I,Arzu Ergen H,Arikan S,Okay E,Oztürk O,Bayrak S,Isbir T

更新日期：2007-11-01 00:00:00

abstract：:Recent studies have demonstrated that germ-like cells could be differentiated from human umbilical cord mesenchymal stem cells (hUC-MSCs) in vitro. Whether the sexuality of hUC-MSCs affects the formation efficiency of germ-like cells derived from hUC-MSCs is still unclear. To clearly test the formation efficiency of o...

journal_title：Cell biochemistry and function

authors： Qiu P,Bai Y,Pan S,Li W,Liu W,Hua J

更新日期：2013-07-01 00:00:00

abstract：:Several polymorphisms in the CYP1A1 locus have been identified and their genotypes appear to exhibit population frequencies that depend on ethnicity. We studied two CYP1A1 polymorphic sites (position 4889 and 6235) in a group of 212 unrelated healthy individuals belonging to three different Mexican populations (106 Me...

journal_title：Cell biochemistry and function

authors： Fragoso JM,Juárez-Cedillo T,Hernández-Pacheco G,Ramírez E,Zuñiga J,Izaguirre R,de la Peña A,Granados J,Vargas-Alarcón G

更新日期：2005-05-01 00:00:00

abstract：:The effect of citrinin on Ca2+ transport was studied in isolated kidney cortex and liver mitochondria, and baby hamster kidney cultured cells. The mycotoxin significantly inhibited the activity of 2-oxoglutarate and pyruvate dehydrogenases in both kidney cortex and liver mitochondria. Citrinin promoted a decrease in t...

journal_title：Cell biochemistry and function

authors： Chagas GM,Oliveira MA,Campello AP,Kluppel ML

更新日期：1995-03-01 00:00:00

abstract：:The goal of the study was to estimate the effect of a selective V-type H+ -ATPase inhibitor bafilomycin A1 and nicotinic acid adenine dinucleotide phosphate (NAADP) on energetic processes in NK/Ly cell by directly measuring the respiration of isolated mitochondria and ATPase activities. NAADP (7 μM) increased the acti...

journal_title：Cell biochemistry and function

authors： Hreniukh V,Bychkova S,Kulachkovsky O,Babsky A

更新日期：2016-12-01 00:00:00

abstract：:Involvement of complications is considered to be one of the major factors in the prognosis of diabetes mellitus (DM). Recent studies indicate that most diabetic complications such as nephropathy and hypertension are vascular-originated. Renin-angiotensin involvement, especially changes in ACE activity level, is consid...

journal_title：Cell biochemistry and function

authors： Ustündağ B,Canatan H,Cinkilinç N,Halifeoğlu I,Bahçecioğlu IH

更新日期：2000-03-01 00:00:00

abstract：:The number of reports on the effects induced by electromagnetic radiation (EMR) in various cellular systems is still increasing. Until now no satisfactory mechanism has been proposed to explain the biological effects of this radiation. Oxygen free radicals may play a role in mechanisms of adverse effects of EMR. This ...

journal_title：Cell biochemistry and function

authors： Irmak MK,Fadillioğlu E,Güleç M,Erdoğan H,Yağmurca M,Akyol O

更新日期：2002-12-01 00:00:00

abstract：:Sonic hedgehog (Shh) plays important roles in developmental of vertebrate animal central nervous system (CNS), and Gli is its downstream signal molecule. Shh signalling is essential for pattern formation, cell-fate specification, axon guidance, proliferation, survival and differentiation of neurons in CNS development....

journal_title：Cell biochemistry and function

authors： Li X,Li Y,Li S,Li H,Yang C,Lin J

更新日期：2020-08-25 00:00:00

abstract：:Beta-glucosidase activity was evaluated in situ by means of fluorogenic probes in normal human fibroblasts and fibroblasts from homozygous carriers of the Gaucher trait. Probe internalization, targeting to lysosomes and post-cleavage probe retention were the primary concerns. Internalization and targeting were attempt...

journal_title：Cell biochemistry and function

authors： Kohen E,Kohen C,Hirschberg JG,Santus R,Grabowski G,Mangel W,Gatt S,Prince J

更新日期：1993-09-01 00:00:00

abstract：:The aim of the present studies was to determine whether the mechanism of biological action of garlic-derived sulfur compounds in human hepatoma (HepG2) cells can be dependent on the presence of labile sulfane sulfur in their molecules. We investigated the effect of allyl sulfides from garlic: monosulfide, disulfide an...

journal_title：Cell biochemistry and function

authors： Iciek M,Kwiecień I,Chwatko G,Sokołowska-Jeżewicz M,Kowalczyk-Pachel D,Rokita H

更新日期：2012-04-01 00:00:00

abstract：:Proteins destined for degradation by the ubiquitin-proteasome system are labelled with a 76-amino acid peptide, ubiquitin, through a series of conjugation steps by the E1, E2 and E3 enzymes respectively. Ubiquitin carboxy-terminal hydrolase 37 (UCH37) belongs to the UCH proteases family that deubiquitinates ubiquitin-...

journal_title：Cell biochemistry and function

authors： Chen Z,Niu X,Li Z,Yu Y,Ye X,Lu S,Chen Z

更新日期：2011-03-01 00:00:00

abstract：:The flavanone hesperetin is known to decrease basal glucose uptake, although the inhibitory mechanism is largely unknown. Here, we used MDA-MB-231 breast cancer cells to investigate the molecular pathways affected by hesperetin. The results indicate that the suppression of glucose uptake is caused by the down-regulati...

journal_title：Cell biochemistry and function

authors： Yang Y,Wolfram J,Boom K,Fang X,Shen H,Ferrari M

更新日期：2013-07-01 00:00:00

abstract：:Ras-GTPases regulate many central signalling pathways in the cell. Hypoxia induces nitrosative/oxidative stress and dysregulates Ras-dependent downstream processes. H-Ras possesses two cysteine residues (C181 and C184) in the C-termini, which are palmitoylated once or twice. Palmitoylation is sufficient for promoting ...

journal_title：Cell biochemistry and function

authors： Goloshvili G,Barbakadze T,Mikeladze D

更新日期：2019-10-01 00:00:00

abstract：:We investigated the effect of rosiglitazone (RSG), a high-affinity ligand for the peroxisome proliferator-activated receptor gamma which mediates insulin-sensitizing actions, on the lipid profile and oxidative status in streptozotocin (STZ)-induced Type 2 diabetes mellitus (DM) rats. Wistar albino male rats were rando...

journal_title：Cell biochemistry and function

authors： Kavak S,Ayaz L,Emre M,Inal T,Tamer L,Günay I

更新日期：2008-06-01 00:00:00

abstract：:Proliferating-cell nuclear antigen (PCNA), also known as cyclin, is synthesized in proliferative cells and recently was identified as DNA polymerase-delta auxiliary protein. In this paper, the association of PCNA to the proliferative cells of plants was analysed using both autoantibodies to PCNA obtained from a patien...

journal_title：Cell biochemistry and function

authors： Daidoji H,Takasaki Y,Nakane PK

更新日期：1992-06-01 00:00:00

abstract：:Epidermal growth factor plays a major role in breast cancer cell proliferation, survival, and metastasis. Quercetin, a bioactive flavonoid, is shown to exhibit anticarcinogenic effects against various cancers including breast cancer. Hence, the present study was designed to evaluate the effects of gold nanoparticles-c...

journal_title：Cell biochemistry and function

authors： Balakrishnan S,Mukherjee S,Das S,Bhat FA,Raja Singh P,Patra CR,Arunakaran J

更新日期：2017-06-01 00:00:00