Hesperetin impairs glucose uptake and inhibits proliferation of breast cancer cells.

abstract：:Research on prostate cancer progression has focused extensively on the concept of miRNA, which can operate either as promoters or as suppressors of carcinogenesis. Moreover, recent genetic studies and emerging functional work show that strikingly similar and overlapping pathways are involved in prostate carcinogenesis...

journal_title：Cell biochemistry and function

authors： Farooqi AA,Naqi A,Qureshi MZ,Rana A,Khan A,Riaz AM,Afzal SM,Rasheed N,Bhatti S

更新日期：2012-10-01 00:00:00

abstract：:Retinopathy of prematurity, a leading cause of visual impairment in low birth-weight infants, remains a crucial therapeutic challenge. Ciliary neurotrophic factor (CNTF) is a promyelinating trophic factor that promotes rod and cone photoreceptor survival and cone outer segment regeneration in the degenerating retina. ...

journal_title：Cell biochemistry and function

authors： Zhou WD,Wang LL,Zhou LB,Bin W,Bao TP,Zhang Y,Shu J,Yang WX,Hui LL,Jin R,Zhuang LL,Zhou GP

更新日期：2017-06-01 00:00:00

abstract：:In pancreatic islets prepared from fed rats and incubated at a low concentration (1.7 mM) of D-glucose, D-mannoheptulose (10.0 mM) virtually fails to affect the metabolism of the hexose. Likewise, in islets from starved rats, the relative extent of the inhibitory action of D-mannoheptulose upon D-glucose metabolism is...

journal_title：Cell biochemistry and function

authors： Picton S,Malaisse WJ

更新日期：1999-03-01 00:00:00

abstract：:Current studies have shown that circular RNAs (circRNAs) and microRNAs (miRNAs) are closely related in acute myocardial infarction (AMI). Previous studies have shown that miR-125b promotes fibrosis and up-regulates in cardiac fibroblasts (CFs), and further experiments showed that circ_LAS1L had multiple binding sites ...

journal_title：Cell biochemistry and function

authors： Sun LY,Zhao JC,Ge XM,Zhang H,Wang CM,Bie ZD

更新日期：2020-06-01 00:00:00

abstract：:Organochalcogens are extensively produced and employed by industry and agriculture, and the risk of occupational and environmental toxicity to them has been poorly understood. Here, we investigated the acute effect of a new organochalcogen 3-methyl-1-phenyl-2-(phenylseleno)oct-2-en-1-one on biochemical and hematologic...

journal_title：Cell biochemistry and function

authors： dos Santos Lacerda D,de Oliveira Castro V,Mascarenhas M,Guerra RB,Dani C,Coitinho A,Gomez R,Funchal C

更新日期：2012-06-01 00:00:00

abstract：:Chemotherapeutic drugs that induce DNA damage have the potential to kill cancer cells, but DNA repair protects cells from damage-induced cell death. Thus, eliminating DNA repair is a potential approach to overcome cell drug resistance. In this study, we observed that the gene expression of C-terminal binding protein i...

journal_title：Cell biochemistry and function

authors： Yang L,Yang B,Wang Y,Liu T,He Z,Zhao H,Xie L,Mu H

更新日期：2019-10-01 00:00:00

abstract：:We studied the effect of PTH (10-100 nM) on transductive mechanisms (adenylate cyclase activity, Ca2+ metabolism, IP3 levels) in cell cultures derived from normal and otosclerotic human bone fragments. The cultured cells were osteoblast-like but with calcitonin-receptors still present and with PTH receptors coupled wi...

journal_title：Cell biochemistry and function

authors： Fanó G,Venti-Donti G,Belia S,Paludetti G,Antonica A,Donti E,Maurizi M

更新日期：1993-12-01 00:00:00

abstract：:In view of the antioxidant properties of melatonin, the effects of melatonin on the oxidative-antioxidative status of tissues affected by diabetes, e.g. liver, heart and kidneys, were investigated in streptozotocin (STZ)-induced diabetic rats in the present study. Concentrations of malondialdehyde (MDA) and reduced gl...

journal_title：Cell biochemistry and function

authors： Aksoy N,Vural H,Sabuncu T,Aksoy S

更新日期：2003-06-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) is an endothelium-specific mitogen and a promising inducer of angiogenesis and lymphangiogenesis. The VEGF receptors on endothelial cell membrane include the tyrosine kinases VEGFR-1 (Flt-1), VEGFR-2 (Flk-1/KDR) and VEGFR-3 (Flt-4). KDR is a major mediator of mitogenic, angiog...

journal_title：Cell biochemistry and function

authors： Ge X,Zhao L,He L,Chen W,Li X

更新日期：2012-03-01 00:00:00

abstract：:Because elevated oxidative stress may exacerbate cardiovascular complications of diabetes mellitus, the current study aimed to investigate the effects of treatment with either vitamin A, an antioxidant, or with insulin on lipid peroxidation products and antioxidant enzyme activities of diabetic rat heart. Also to eval...

journal_title：Cell biochemistry and function

authors： Zobali F,Avci A,Canbolat O,Karasu C

更新日期：2002-06-01 00:00:00

abstract：:Previously mildronate, an aza-butyrobetaine derivative, was shown to be a cytoprotective drug, through its mechanism of action of inhibition of carnitine palmitoyltransferase-1, thus protecting mitochondria from long-chain fatty acid accumulation and subsequent damage. Recently in an azidothymidine (AZT)-induced cardi...

journal_title：Cell biochemistry and function

authors： Pupure J,Fernandes MA,Santos MS,Moreno AJ,Kalvinsh I,Klusa V,Oliveira CR

更新日期：2008-09-01 00:00:00

abstract：:Psoriasis is a common chronic and recurrent inflammatory skin disease with unknown etiology that has been associated with abnormal plasma lipid metabolism and oxidative stress. There are controversial results in the previous studies investigating oxidant/antioxidant systems in psoriasis.The aim of this work was to eva...

journal_title：Cell biochemistry and function

authors： Toker A,Kadi M,Yildirim AK,Aksoy H,Akçay F

更新日期：2009-04-01 00:00:00

abstract：:Gout is an inflammatory joint disorder characterized by hyperuricaemia and precipitation of monosodium urate crystals in the joints. In the present study, we aimed to investigate the anti-inflammatory effect of trikatu, a herbal compound in monosodium urate crystal-induced inflammation in rats, an experimental model f...

journal_title：Cell biochemistry and function

authors： Murunikkara V,Rasool M

更新日期：2014-01-01 00:00:00

abstract：:Sonic hedgehog (Shh) plays important roles in developmental of vertebrate animal central nervous system (CNS), and Gli is its downstream signal molecule. Shh signalling is essential for pattern formation, cell-fate specification, axon guidance, proliferation, survival and differentiation of neurons in CNS development....

journal_title：Cell biochemistry and function

authors： Li X,Li Y,Li S,Li H,Yang C,Lin J

更新日期：2020-08-25 00:00:00

abstract：:Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease that is characterized by selective destruction of insulin secreting pancreatic islets beta-cells. The formation of cytokines (IL-1beta, IL-6, TNF-alpha, etc.) leads to extensive morphological damage of beta-cells, DNA fragmentation, decrease of glucos...

journal_title：Cell biochemistry and function

authors： Briede J,Stivrina M,Stoldere Dz,Vigante B,Duburs G

更新日期：2007-11-01 00:00:00

abstract：:CD36, a multifunctional adhesion receptor e.g. for thrombospondin and collagen, as well as a scavenger receptor for oxidized low density lipoprotein, is expressed e.g. on platelets and monocytes. By this dual role it might be involved in early steps of atherosclerosis like the recruitment of monocytes and formation of...

journal_title：Cell biochemistry and function

authors： Pietsch A,Weber C,Goretzki M,Weber PC,Lorenz RL

更新日期：1995-09-01 00:00:00

abstract：:The aim of this study was to evaluate the role of mitochondria in the recovery of cardiac energetics induced by ischaemic preconditioning at reperfusion. Isolated rat hearts were aerobically perfused (control), subjected to global ischaemia and reperfusion (reperfusion), or subjected to 3 brief cycles of ischaemia/rep...

journal_title：Cell biochemistry and function

authors： Muscari C,Bonafè F,Gamberini C,Giordano E,Lenaz G,Caldarera CM

更新日期：2006-11-01 00:00:00

abstract：:The time-course of incorporation of NBD-cholesterol by macrophages (Ma) and lymphocytes (LY) obtained from untreated and thioglycollate-injected (thio) rats was investigated. NBD-cholesterol incorporation was also examined in Ma obtained from untreated rats and stimulated in vitro by lipopolysaccharide (LPS) and phorb...

journal_title：Cell biochemistry and function

authors： Portioli Silva EP,Peres CM,Roberto Mendonça J,Curi R

更新日期：2004-01-01 00:00:00

abstract：:The effects of several novel monosaccharides upon thymidine incorporation into both normal and tumour cells were investigated. The monosaccharide 2-deoxy-3-[1-(R)-(ethoxycarbonyl)ethyl]- alpha-D-allo-pyranose had the most inhibitory effect on proliferation, with the (S)-enantiomer having less inhibitory effects. The c...

journal_title：Cell biochemistry and function

authors： Colquhoun A,Alaluf S,Bradley A,Gemmell N,Gibbs G,Osborn HM,Harwood LM,Newsholme EA

更新日期：1997-12-01 00:00:00

abstract：:The subcellular distribution of newly absorbed iron in isolated mouse duodenal enterocytes was investigated by analytical subcellular fractionation using sucrose density gradient centifugation. Two major peaks of mucosal 59Fe activity were observed: one soluble and one particulate (density 1.18-1.20 g ml-1). The latte...

journal_title：Cell biochemistry and function

authors： Snape S,Simpson RJ,Peters TJ

更新日期：1990-04-01 00:00:00

abstract：:Scanning and integrating microdensitometry of azure B- and Coomassie brilliant blue G-stained tissue sections was used to measure the levels of RNA and protein, respectively, in pyramidal neurons of the insular cortex (INS) and midfrontal gyrus (MFG) in patients with Alzheimer's disease (AD) and age-matched, nondement...

journal_title：Cell biochemistry and function

authors： Colurso GJ,Kan RK,Anthony A

更新日期：1995-12-01 00:00:00

abstract：:The purpose of this study was to investigate the oxidative status in experimental hypothyroidism and the antioxidant effect of taurine supplementation. Forty male Sprague Dawley rats were randomly divided into four groups (group 1, control; group 2, control + taurine; group 3, propylthiouracil (PTU); group 4, PTU + ta...

journal_title：Cell biochemistry and function

authors： Taş S,Dirican M,Sarandöl E,Serdar Z

更新日期：2006-03-01 00:00:00

abstract：:The aim of the present study was to measure plasma uric acid (UA) levels and superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and xanthine oxidase (XO) activities and to evaluate the relationship between these parameters and the severity of pre-eclampsia. Twenty-five pre-eclamptic, 15 healthy pregnant and 1...

journal_title：Cell biochemistry and function

authors： Yildirim A,Altinkaynak K,Aksoy H,Sahin YN,Akcay F

更新日期：2004-07-01 00:00:00

abstract：:The use of Nigerian bonny light crude oil (BLCO) in the treatment of gastrointestinal disorders, burns, foot ulcers and reproductive capacity is a common practice in the southern part of Nigeria. Towards understanding the mechanism and the reversibility of hepatotoxicity induced by BLCO, adult male Wistar rats were or...

journal_title：Cell biochemistry and function

authors： Adedara IA,Farombi EO

更新日期：2012-08-01 00:00:00

abstract：:Growth factors are biologically-active mediators that bind to specific receptors on target cells and regulate genes involved in cell growth, wound healing and regeneration. In the case of wound healing, a proper wound dressing is needed to cover the wound area, protect the damaged tissue, and if possible to activate c...

journal_title：Cell biochemistry and function

authors： Grdisa M,Popović M,Hrzenjak T

更新日期：2004-11-01 00:00:00

abstract：:The protective effects of carnosine as a natural dipeptide were investigated in mouse bone marrow cells against genotoxicity induced by cyclophosphamide. Mice were injected with solutions of carnosine at three different doses (10, 50 and 100 mg kg(-1) bw) for five consecutive days. On the fifth day of treatment, mice ...

journal_title：Cell biochemistry and function

authors： Naghshvar F,Abianeh SM,Ahmadashrafi S,Hosseinimehr SJ

更新日期：2012-10-01 00:00:00

abstract：:Nuclear T3 specific binding sites were characterized by Scatchard analyses of L-125I-T3 binding to nuclei extracted from freshly isolated and 1, 2 and 6 day-cultured hepatocytes. The results demonstrate a marked decrease in T3 binding capacity of nuclei extracted from 1 day-cultured cells followed by an almost complet...

journal_title：Cell biochemistry and function

authors： Goglia F,Gallo G,Palmero S,Voci A,Fugassa E

更新日期：1985-04-01 00:00:00

abstract：:Dietary soy lecithin supplementation decreases hyperlipidemia and influences lipid metabolism. Although this product is used by diabetic patients, there are no data about the effect of soy lecithin supplementation on the immune system. The addition of phosphatidylcholine, the main component of lecithin, to a culture o...

journal_title：Cell biochemistry and function

authors： Miranda DT,Batista VG,Grando FC,Paula FM,Felício CA,Rubbo GF,Fernandes LC,Curi R,Nishiyama A

更新日期：2008-12-01 00:00:00

abstract：:Regeneration remains a major challenge in skeletal muscle repair after injury. Recently, transforming growth factor-β (TGF-β)/Smad pathway was found to play an important role in inhibiting myogenesis, a crucial stage in skeletal muscle regeneration. In our previous study, microRNA-122-5p (miR-122) was proved to have t...

journal_title：Cell biochemistry and function

authors： Ding Z,Lin J,Sun Y,Cong S,Liu S,Zhang Y,Chen Q,Chen J

更新日期：2020-03-01 00:00:00

abstract：:The effects of 1,25-dihydroxyvitamin D3 are mediated by binding to a specific intracellular vitamin D receptor (VDR), which has been identified in a variety of tissues. Certain polymorphisms in the VDR gene have been associated with various neoplasms. For this purpose, we studied whether VDR TaqI or FokI genotype are ...

journal_title：Cell biochemistry and function

authors： Yaylim-Eraltan I,Arzu Ergen H,Arikan S,Okay E,Oztürk O,Bayrak S,Isbir T

更新日期：2007-11-01 00:00:00