Lipases operative at the fat cell surface: attempt at an integrated approach.

abstract：:We investigated the effect of rosiglitazone (RSG), a high-affinity ligand for the peroxisome proliferator-activated receptor gamma which mediates insulin-sensitizing actions, on the lipid profile and oxidative status in streptozotocin (STZ)-induced Type 2 diabetes mellitus (DM) rats. Wistar albino male rats were rando...

journal_title：Cell biochemistry and function

authors： Kavak S,Ayaz L,Emre M,Inal T,Tamer L,Günay I

更新日期：2008-06-01 00:00:00

abstract：:We report a functional characterisation of the novel protein MGC13096. MGC13096 over-expression restrained proliferation of HEK293T cells. DNA/flow cytometry analysis showed that the over-expression of MGC13096 severely delays cell cycle progression at S phase. Transcription factors such as activator protein-1 (AP-1),...

journal_title：Cell biochemistry and function

authors： Chen Q,Yan C,Yan Q,Feng L,Chen J,Qian K

更新日期：2008-03-01 00:00:00

abstract：:The effect of exposure to, followed by consumption of, 10% flax chow from the 18th day of gestation to the 86th day after birth was examined in male and female Fischer 344 rats. Growth curves of the flax chow-fed rats were identical to those of regular chow-fed rats, as were such developmental milestones as pinna deve...

journal_title：Cell biochemistry and function

authors： Hemmings SJ,Barker L

更新日期：2004-03-01 00:00:00

abstract：:Reduced and oxidized glutathione (GSH and GSSG), protein-bound glutathione, lipid peroxidation and antioxidant enzyme activities were determined in the erythrocyte lysates and membranes of type I and II alcoholics in order to clarify the effect of age-of-onset and the duration of the alcohol consumption on erythrocyte...

journal_title：Cell biochemistry and function

authors： Uçar G,Demir B,Uluğ B

更新日期：2005-01-01 00:00:00

abstract：:The effects of several novel monosaccharides upon thymidine incorporation into both normal and tumour cells were investigated. The monosaccharide 2-deoxy-3-[1-(R)-(ethoxycarbonyl)ethyl]- alpha-D-allo-pyranose had the most inhibitory effect on proliferation, with the (S)-enantiomer having less inhibitory effects. The c...

journal_title：Cell biochemistry and function

authors： Colquhoun A,Alaluf S,Bradley A,Gemmell N,Gibbs G,Osborn HM,Harwood LM,Newsholme EA

更新日期：1997-12-01 00:00:00

abstract：:Differences in metabolism of drugs can lead to severe toxicity or therapeutic failure. In addition to cytochrome P450 2D6, which plays a critical role in drug metabolism, ABCB1 encoded P-glycoprotein (PGP) is also an important determinant in drug bioavailability. The genes encoding these molecules are highly variable ...

journal_title：Cell biochemistry and function

authors： Correia C,Santos P,Coutinho AM,Vicente AM

更新日期：2009-06-01 00:00:00

abstract：:In moderate physical exercise, the transition from predominantly anaerobic towards predominantly aerobic metabolism is a key step to improve performance. Increase in the supply of oxygen and nutrients, such as free fatty acids (FFA) and glucose, which accompanies high blood flow, is required for this transition. The m...

journal_title：Cell biochemistry and function

authors： Hirabara SM,Silveira LR,Abdulkader FR,Alberici LC,Procopio J,Carvalho CR,Pithon-Curi TC,Curi R

更新日期：2006-11-01 00:00:00

abstract：:Nuclear, chromatin and microsomal fractions were isolated from hepatocytes prepared from rats injected with [32P]O4(2-) and killed subsequently at times between 1 and 48 h. Specific activities of the total phospholipids (PL) were determined for each subcellular fraction. The major points noted were the initial specifi...

journal_title：Cell biochemistry and function

authors： Viola-Magni MP,Gahan PB,Albi E,Iapoce R,Gentilucci PF

更新日期：1986-10-01 00:00:00

abstract：:The objectives of study were (a) to determine alteration of feeding, glucose level and oxidative stress and (b) to investigate expression and localization of cannabinoid receptors in type-2 diabetic rat pancreas treated with Δ(9)-tetrahydrocannabinol (Δ(9)-THC). Rats were randomly divided into four groups: control, Δ(...

journal_title：Cell biochemistry and function

authors： Coskun ZM,Bolkent S

更新日期：2014-10-01 00:00:00

abstract：:The effect of the tryptophan hydroxylase inhibitor, PCPA methylester, the serotonin reuptake inhibitor fluoxetine and MAO-A inhibitor clorgyline on the serotonin content of rat immune cells was studied, using labelled antibodies and flow cytometry. Each molecule significantly increased in males the serotonin concentra...

journal_title：Cell biochemistry and function

authors： Pállinger E,Csaba G

更新日期：2007-09-01 00:00:00

abstract：:The protective effects of betaine in ethanol hepatotoxicity were investigated in 24 female wistar albino rats. Animals were divided into three groups: control, ethanol and ethanol + betaine group. Animals were fed liquid diets and consumed approximately 60 diet per day. Rats were fed ethanol 8 kg(- 1) day(- 1). The et...

journal_title：Cell biochemistry and function

authors： Kanbak G,Inal M,Bayçu C

更新日期：2001-12-01 00:00:00

abstract：:Dietary soy lecithin supplementation decreases hyperlipidemia and influences lipid metabolism. Although this product is used by diabetic patients, there are no data about the effect of soy lecithin supplementation on the immune system. The addition of phosphatidylcholine, the main component of lecithin, to a culture o...

journal_title：Cell biochemistry and function

authors： Miranda DT,Batista VG,Grando FC,Paula FM,Felício CA,Rubbo GF,Fernandes LC,Curi R,Nishiyama A

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:Hydrogen peroxide (H(2)O(2)) is a potent reactive oxygen species that causes cardiomyocytes injury. As an important cytokine, interleukin 6 (IL-6) has cardioprotective effects as it plays an essential role in the late phase of preconditioning. Our work is to investigate if IL-6 preconditioning has protective ...

journal_title：Cell biochemistry and function

authors： Jia Y,Zhou F,Deng P,Fan Q,Li C,Liu Y,Fu X,Zhou Y,Xu X,Sun X

更新日期：2012-07-01 00:00:00

abstract：:Pig thyroid Golgi vesicles incubated in a suitable medium were able to concentrate iodide from the medium. This trapping required the integrity of the vesicles, was time- and temperature-dependent, and was inhibited by a competitive inhibitor of iodide active transport (perchlorate), suggesting a facilitated transport...

journal_title：Cell biochemistry and function

authors： Bastiani P,Rognoni JB

更新日期：1985-01-01 00:00:00

abstract：:Uptake of polyamines has been investigated extensively in many cells, but not in placenta, where the polyamine-polyamine oxidase system is supposed to have an immunoregulatory function in pregnancy. Due to the importance of the transfer in this tissue, we have started this study. JAR human placental choriocarcinoma ce...

journal_title：Cell biochemistry and function

authors： Fontana L,Cravanzola C,Colombatto S,Grillo MA

更新日期：1996-09-01 00:00:00

abstract：:While transcription plays an obviously important role in gene expression, translation has recently been emerged as a key step that defines the composition and quality of the proteome in the cell of higher eukaryotes including mammals. Selective translation is supposed to be regulated by the structural heterogeneity of...

journal_title：Cell biochemistry and function

authors： Muto A,Sugihara Y,Shibakawa M,Oshima K,Matsuda T,Nadano D

更新日期：2018-08-01 00:00:00

abstract：:Ovarian cancer is one of the most common female malignancies, and cisplatin-based chemotherapy is routinely used in locally advanced ovarian cancer patients. Acquired or de novo cisplatin resistance remains the barrier to patient survival, and the mechanisms of cisplatin resistance are still not well understood. In th...

journal_title：Cell biochemistry and function

authors： Yu R,Jin H,Jin C,Huang X,Lin J,Teng Y

更新日期：2018-03-01 00:00:00

abstract：:The influence of the 1,4-dihydropyridines (DHPs), water-soluble glutapyrone available as sodium, potassium and ammonium salts of 2-(2,6-dimethyl-3,5-diethoxycarbonyl-1,4-DHP-4-carboxamide)glutaric acid, from one side, and a lipophylic cerebrocrast, 2-propoxyethyl 2,6-dimethyl-4-(2-difluoromethoxyphenyl)-1,4-DHP-3,5-di...

journal_title：Cell biochemistry and function

authors： Velena A,Skujiņs A,Svirskis S,Bisenieks E,Uldriķis J,Poikans J,Duburs G,Klusa V

更新日期：1997-09-01 00:00:00

abstract：:Cyclophosphamide (CP) has potential urotoxicity such as hemorrhagic cystitis (HC). 2-Mercaptoethane sulfonate (mesna) has been widely used as an effective agent against CP-induced cystitis, but significant HC has still been encountered clinically. In recent studies, mesna was shown to be more effective if combined wit...

journal_title：Cell biochemistry and function

authors： Sadir S,Deveci S,Korkmaz A,Oter S

更新日期：2007-09-01 00:00:00

abstract：:Metabolism of arabinose 5-P, ribose 5-P and glucose 6-P in permeabilized and resealed Morris hepatoma 5123TC cells was investigated by measuring the contribution of these compounds to nucleic acid biosynthesis. The level of [14C]-arabinose (non-phosphorylated) incorporation into nucleic acids was slight, presumably du...

journal_title：Cell biochemistry and function

authors： Arora KK,Williams JF

更新日期：1987-10-01 00:00:00

abstract：:Endothelial dysfunction is recognized as the initial detectable stage of cardiovascular disease, a serious complication of diabetes. In this study, we evaluated effects of myricetin on high glucose (HG)-elicited oxidative damage in human umbilical vein endothelial cells (HUVECs). The cells were pre-incubated with myri...

journal_title：Cell biochemistry and function

authors： Aminzadeh A,Bashiri H

更新日期：2020-01-01 00:00:00

abstract：:The aim of the present work was to investigate the mechanisms of oxidative damage of the liver mitochondria under diabetes and intoxication in rats as well as to evaluate the possibility of corrections of mitochondrial disorders by pharmacological doses of melatonin. The experimental (30 days) streptozotocin-induced d...

journal_title：Cell biochemistry and function

authors： Cheshchevik VT,Dremza IK,Lapshina EA,Zabrodskaya SV,Kujawa J,Zavodnik IB

更新日期：2011-08-01 00:00:00

abstract：:Sprouty1 protein belongs to a family of receptor tyrosine kinase-mediated signaling inhibitors, whose members are usually regulated by growth factors to form a negative feedback loop. Correspondingly fluctuations of Sprouty1 mRNA in response to single growth factors have been observed. In this report, we investigate S...

journal_title：Cell biochemistry and function

authors： Kral RM,Mayer CE,Vanas V,Gsur A,Sutterlüty-Fall H

更新日期：2014-01-01 00:00:00

abstract：:Glucocorticoids are important for skeletal muscle energy metabolism, regulating glucose utilization, insulin sensitivity, and muscle mass. Nicotinamide adenine dinucleotide phosphate-dependent 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)-mediated glucocorticoid activation in the sarcoplasmic reticulum (SR) is in...

journal_title：Cell biochemistry and function

authors： Zielinska AE,Fletcher RS,Sherlock M,Doig CL,Lavery GG

更新日期：2017-07-01 00:00:00

abstract：:CYR61 is one of the six proteins of the CCN family of proteins known to play diverse roles in angiogenesis, cellular proliferation, survival, migration and wound healing. However, the specific function of CYR61 in cancer is unclear, and the literature remains controversial. We used quantitative real-time PCR to establ...

journal_title：Cell biochemistry and function

authors： Jandova J,Beyer TE,Meuillet EJ,Watts GS

更新日期：2012-12-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) is an endothelium-specific mitogen and a promising inducer of angiogenesis and lymphangiogenesis. The VEGF receptors on endothelial cell membrane include the tyrosine kinases VEGFR-1 (Flt-1), VEGFR-2 (Flk-1/KDR) and VEGFR-3 (Flt-4). KDR is a major mediator of mitogenic, angiog...

journal_title：Cell biochemistry and function

authors： Ge X,Zhao L,He L,Chen W,Li X

更新日期：2012-03-01 00:00:00

abstract：:The activity of glutathione reductase (GHSR) in extracts of kidney, liver and testis of rats infected with Trypanosoma congolense decreased with every wave of parasitemia. The implications of these observations as they relate to the risk of oxidative stress are discussed. ...

journal_title：Cell biochemistry and function

authors： Nok AJ,Onyenekwe PC,Ibrahim S,Bature A,Ogbadoyi E

更新日期：1995-06-01 00:00:00

abstract：:The immunological induction of arthritis in the knee of the rabbit is well established as a model for human rheumatoid arthritis. It has the special advantage of allowing the development of the condition, and the effect of disease-modifying agents, to be followed. Attention has been focussed on the activity of glucose...

journal_title：Cell biochemistry and function

authors： Pitsillides AA,Blake SM,Glynn LE,Bitensky L,Chayen J

更新日期：1990-10-01 00:00:00

abstract：:The aim of this study was to evaluate the role of mitochondria in the recovery of cardiac energetics induced by ischaemic preconditioning at reperfusion. Isolated rat hearts were aerobically perfused (control), subjected to global ischaemia and reperfusion (reperfusion), or subjected to 3 brief cycles of ischaemia/rep...

journal_title：Cell biochemistry and function

authors： Muscari C,Bonafè F,Gamberini C,Giordano E,Lenaz G,Caldarera CM

更新日期：2006-11-01 00:00:00

abstract：:The effect of influenza strains A (H3N2) and B, isolated during the seasons of 1994 and 1995 in the Czech Republic, on MDCK cells was studied. Various concentrations of virus and conditions of nutrition were used during the cell culture. The virus replication and consequently fragmentation of genomic DNA together with...

journal_title：Cell biochemistry and function

authors： Hornícková Z

更新日期：1997-06-01 00:00:00