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Improvement in HIV-associated motor slowing after antiretroviral therapy including protease inhibitors.

Abstract：

:A study of neuropsychological performance was conducted in 33 HIV+ patients initiating highly active antiretroviral therapy (HAART). Grooved Pegboard (GP) non-dominant hand performance improved in 23/33 (70%) subjects (P=0.002). Among 23 patients with motor slowing (GP non-dominant hand z score < -1.0) at baseline, 18 (78%) improved on the GP non-dominant hand test after initiating HAART (P=0.001). GP non-dominant hand performance improved longitudinally in HIV+ patients initiating HAART, while matched HIV+ controls not on HAART did not change (P=0.045). Significant improvement in motor performance can occur after HAART in HIV+ patients with impairment.

journal_name

J Neurovirol

journal_title

Journal of neurovirology

authors

Sacktor NC,Skolasky RL,Lyles RH,Esposito D,Selnes OA,McArthur JC

doi

10.3109/13550280009006385

subject

Has Abstract

pub_date

2000-02-01 00:00:00

pages

84-8

issue

1

eissn

1355-0284

issn

1538-2443

journal_volume

6

pub_type

临床试验,杂志文章

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