Alterations in blood-brain barrier glucose transport in SIV-infected macaques.

abstract：:Previous diffusion tensor imaging (DTI) studies found that human immunodeficiency virus (HIV) infection led to white matter (WM) microstructure degeneration. Most of the DTI studies were cross-sectional and thus merely investigated only one specific point in the disease. In order to systematically study the WM impairm...

journal_title：Journal of neurovirology

authors： Tang Z,Dong E,Liu J,Liu Z,Wei W,Wang B,Li H,Tian J

更新日期：2016-04-01 00:00:00

abstract：:Human parechoviruses (HPeV) are classified into 14 genotypes. HPeV1 and HPeV2 are the most prevalent genotypes in young children, which have been associated with mild to severe diseases. This study was conducted to investigate the involvement of HPeVs in aseptic meningitis and sepsis-like illness in Iran. Viral RNA wa...

journal_title：Journal of neurovirology

authors： Rahimi P,Naser HM,Siadat SD,Sohrabi A,Mostafavi E,Motamedirad M,Bahramali G,Sadat SM,Ardestani MS

更新日期：2013-12-01 00:00:00

abstract：:There is controversy with regard to the entry pathway of the rabies virus (RABV) into the central nervous system (CNS). Some authors have suggested that the virus inoculated at the periphery is captured and transported to CNS only by motor neurons; however, it has been reported that dorsal root ganglia (DRG) sensory n...

journal_title：Journal of neurovirology

authors： Velandia-Romero ML,Castellanos JE,Martínez-Gutiérrez M

更新日期：2013-08-20 00:00:00

abstract：:Toscana virus (Bunyaviridae family, Phlebovirus genus) is a sandfly fever virus responsible for human neurological infections. Sandfly viruses are transmitted by insect vectors (Phlebotomus species) and the infection is present in climatic areas that allow the life cycle of the vector. The arthropode-borne Toscana vir...

journal_title：Journal of neurovirology

authors： Valassina M,Cusi MG,Valensin PE

更新日期：2003-12-01 00:00:00

abstract：:A significant number of human immunodeficiency virus type 1 (HIV-1)-infected patients are alcoholics. Either alcohol or HIV alone induces morphological and functional damage to the nervous system. HIV-1 Tat is a potent transcriptional activator of the viral promoter, with the ability to modulate a number of cellular r...

journal_title：Journal of neurovirology

authors： Brailoiu E,Brailoiu GC,Mameli G,Dolei A,Sawaya BE,Dun NJ

更新日期：2006-02-01 00:00:00

abstract：:The recent ability to quantitate and localize the interaction of antigen-specific T cells in the central nervous system during infectious and autoimmune diseases will greatly enhance our understanding of the molecular and biologic basis of virus-induced diseases of the nervous and other systems. ...

journal_title：Journal of neurovirology

authors： Oldstone MB

更新日期：2004-08-01 00:00:00

abstract：:Recent evidence suggests that HIV-1 Vpr exists in soluble form in the serum and cerebrospinal fluid (CSF). Further, its abundance in the bloodstream, and the CSF, and its activity on other cell types suggest that it could have an effect on brain activity. Using mixed embryonic rat brain cultures as a model to examine ...

journal_title：Journal of neurovirology

authors： Huang MB,Weeks O,Zhao LJ,Saltarelli M,Bond VC

更新日期：2000-06-01 00:00:00

abstract：:Injection drug use has been recognized as a major risk factor for acquired immunodeficiency syndrome (AIDS) from the outset of the epidemic. Cocaine, one of the most widely abused drugs in the United States, can both impair the functions of macrophages and CD4(+) lymphocytes and also activate human immunodeficiency vi...

journal_title：Journal of neurovirology

authors： Dhillon NK,Williams R,Peng F,Tsai YJ,Dhillon S,Nicolay B,Gadgil M,Kumar A,Buch SJ

更新日期：2007-12-01 00:00:00

abstract：:Cytomegalovirus (CMV) infections are common and severe complications of HIV infection. The virus involves the nervous system, causing encephalitis, polyradiculomyelitis and peripheral neuropathies. Due to their limited sensitivity, traditional virological approaches, such as virus isolation or antigen detection in the...

journal_title：Journal of neurovirology

authors： Cinque P,Cleator GM,Weber T,Monteyne P,Sindic C,Gerna G,van Loon AM,Klapper PE

更新日期：1998-02-01 00:00:00

abstract：:HIV-1 viral proteins have been implicated in endothelial dysfunction, which is a major determinant of ischaemic stroke risk in HIV-infected individuals. Polymorphisms in HIV-1 viral protein R (Vpr) may alter its potential to promote endothelial dysfunction, by modifying its effects on viral replication, reactivation o...

journal_title：Journal of neurovirology

authors： McMullen K,Bateman K,Stanley A,Combrinck M,Engelbrecht S,Bryer A

更新日期：2021-01-18 00:00:00

abstract：:Previous animal studies have identified a C31S residue substitution in the C30C31 dicysteine motif of the Tat protein that is associated with reduced neurovirulence in clade C human immunodeficiency virus (HIV). However, clinical studies of patients infected with clade C HIV have reported significant levels of cogniti...

journal_title：Journal of neurovirology

authors： Paul RH,Joska JA,Woods C,Seedat S,Engelbrecht S,Hoare J,Heaps J,Valcour V,Ances B,Baker LM,Salminen LE,Stein DJ

更新日期：2014-12-01 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) play important roles in regulating eukaryotic genome replication and gene expression in diverse biological systems. Here, we identified lncRNAs transcribed from pseudorabies virus (PRV)-infected PK-15 cells. Based on high-throughput sequencing data, we obtained 87,263,926 and 93,947,628 c...

journal_title：Journal of neurovirology

authors： Guan X,Liu J,Jiang H,Wu CX,Chen HC,Liu ZF

更新日期：2018-10-01 00:00:00

abstract：:Most natural killer (NK) T cells express an invariant Valpha14 T-cell receptor. To explore the contribution of NKT cells in an animal model for multiple sclerosis, Theiler's murine encephalomyelitis virus (TMEV) infection, TMEV-infected mice were treated with Valpha14 antibody. Treatment during the early stage of infe...

journal_title：Journal of neurovirology

authors： Tsunoda I,Tanaka T,Taniguchi M,Fujinami RS

更新日期：2009-01-01 00:00:00

abstract：:HIV-1 infection results in a dementing illness affecting 20% of patients with AIDS. Several HIV-1 genes have been implicated in the pathogenesis of HIV-induced neurological disease. To search for distinct HIV-1 sequences associated with the development of dementia, brain-derived tat, env, and pol sequences were examin...

journal_title：Journal of neurovirology

authors： Bratanich AC,Liu C,McArthur JC,Fudyk T,Glass JD,Mittoo S,Klassen GA,Power C

更新日期：1998-08-01 00:00:00

abstract：:The article "Progressive multifocal leukoencephalopathy in rituximab-treated rheumatic diseases: a rare event," written by Joseph R. Berger, Vineeta Malik, Stuart Lacey, Paul Brunetta, and Patricia B. Lehane3, was originally published electronically on the publisher's internet portal (currently SpringerLink). ...

journal_title：Journal of neurovirology

authors： Berger JR,Malik V,Lacey S,Brunetta P,Lehane PB

更新日期：2018-06-01 00:00:00

abstract：:Older HIV-infected men are at higher risk for both depression and cognitive impairments, compared to HIV-uninfected men. We evaluated the association between longitudinal patterns of depressive symptoms and attention/executive function in HIV-infected and HIV-uninfected men aged 50+ years to understand whether HIV inf...

journal_title：Journal of neurovirology

authors： Armstrong NM,Surkan PJ,Treisman GJ,Sacktor NC,Irwin MR,Teplin LA,Stall R,Martin EM,Becker JT,Munro C,Levine AJ,Jacobson LP,Abraham AG

更新日期：2017-08-01 00:00:00

abstract：:Quinolinic acid (QUIN) is a tryptophan metabolite which has been found to be an excitotoxin in rats, although its toxicity in humans is unknown. QUIN has been implicated in the pathogenesis of AIDS dementia complex. This study examined the effect of QUIN on human fetal brain tissue in vitro. After at least 14 days in ...

journal_title：Journal of neurovirology

authors： Kerr SJ,Armati PJ,Brew BJ

更新日期：1995-12-01 00:00:00

abstract：:After uniocular anterior chamber (AC) inoculation of herpes simplex virus type 1 (HSV-1), virus and TNF alpha (TNF-alpha) are detected in the suprachiasmatic nuclei (SCN). The goal of this study was to investigate the role of TNF-alpha and macrophages in the brain of HSV-1-infected BALB/c mice. Mice were treated with ...

journal_title：Journal of neurovirology

authors： Fields M,Zheng M,Zhang M,Atherton SS

更新日期：2006-12-01 00:00:00

abstract：:A postmarketing surveillance study was undertaken to investigate the safety and efficacy of interferon-alpha for human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy (HAM) under routine treatment conditions. A total of 273 cases from 91 medical institutions were registered into the survey. So far, 167...

journal_title：Journal of neurovirology

authors： Arimura K,Nakagawa M,Izumo S,Usuku K,Itoyama Y,Kira J,Osame M

更新日期：2007-08-01 00:00:00

abstract：:B-lymphoblastoid cell-lines may develop spontaneously in mononuclear cells from patients with multiple sclerosis, an observation rarely seen in healthy individuals. Examination of such spontaneously established B-cell lines reveal the presence of Epstein-Barr virus and retrovirus particles. We have speculated that in ...

journal_title：Journal of neurovirology

authors： Haahr S,Munch M

更新日期：2000-05-01 00:00:00

abstract：:The combined effects of human immunodeficiency virus (HIV), obesity, and elevated visceral adipose tissue (VAT) on brain structure are unknown. In a cross-sectional analysis of Multicenter AIDS Cohort Study (MACS) participants, we determined associations between HIV serostatus, adiposity, and brain structure. Men (133...

journal_title：Journal of neurovirology

authors： Lake JE,Popov M,Post WS,Palella FJ,Sacktor N,Miller EN,Brown TT,Becker JT

更新日期：2017-06-01 00:00:00

abstract：:To determine the possible influence of satellite glial cells on restricting the spread of herpes simplex virus in the peripheral nervous system, HSV replication was studied in clonally derived cultures of satellite glial cells from adult animals. Satellite cells were purified by exploiting their close anatomical assoc...

journal_title：Journal of neurovirology

authors： Wilkinson R,Leaver C,Simmons A,Pereira RA

更新日期：1999-08-01 00:00:00

abstract：:Combination antiretroviral therapy (CART) has greatly reduced medical morbidity and mortality with HIV infection, but high rates of HIV-associated neurocognitive disorders (HAND) continue to be reported. Because large HIV-infected (HIV+) and uninfected (HIV-) groups have not been studied with similar methods in the pr...

journal_title：Journal of neurovirology

authors： Heaton RK,Franklin DR,Ellis RJ,McCutchan JA,Letendre SL,Leblanc S,Corkran SH,Duarte NA,Clifford DB,Woods SP,Collier AC,Marra CM,Morgello S,Mindt MR,Taylor MJ,Marcotte TD,Atkinson JH,Wolfson T,Gelman BB,McArthur JC,

更新日期：2011-02-01 00:00:00

abstract：:Zimbabwe is a high prevalence area for HIV infection, and provides opportunities for studying complications of AIDS in both antiretroviral naive and treated groups of patients. Figures for HIV prevalence are among the highest in the world, but the number of people receiving treatment is very small. Economic and politi...

journal_title：Journal of neurovirology

authors： Mielke J

更新日期：2005-01-01 00:00:00

abstract：:We present an immunocompetent patient with transverse myelitis (TM) during acute cytomegalovirus (CMV) infection, as evidenced by a reactive serum CMV IgM and CMV viremia. The patient had an excellent outcome after receiving only high-dose methylprednisolone. Given concerns that practitioners may have around the use o...

journal_title：Journal of neurovirology

authors： Budhram A,Liu Y,Krawczyk M,Chan TLH,Burneo JG,Hosseini-Moghaddam SM,Shoesmith C

更新日期：2019-06-01 00:00:00

abstract：:The cerebral immune response induced by herpes simplex virus (HSV) encephalitis (HSE) was evaluated in susceptible BALB/c and resistant C57BL/6 mice. BALB/c and C57BL/6 (named C57BL/6-high) mice were respectively infected intranasally with 1 × 103 and 5 × 105 plaque-forming units (PFUs) of HSV-1. C57BL/6 mice (named C...

journal_title：Journal of neurovirology

authors： Canivet C,Uyar O,Rhéaume C,Piret J,Boivin G

更新日期：2019-06-01 00:00:00

abstract：:Glycogen synthase kinase-3beta (GSK3beta) role in human immunodeficiency virus(HIV)-associated neurodegeneration has been evidenced by previous investigations. In this study, we investigated the specificity of two GSK3beta-specific inhibitors, AR-A014418 (A) and B6B30 (B) to prevent direct neurotoxicity in primary hum...

journal_title：Journal of neurovirology

authors： Nguyen TB,Lucero GR,Chana G,Hult BJ,Tatro ET,Masliah E,Grant I,Achim CL,Everall IP,HIV Neurobehavioral Research Group.

更新日期：2009-09-01 00:00:00

abstract：:Varicella-zoster virus (VZV) is a ubiquitous human herpes virus typically acquired in childhood when it causes varicella (chickenpox), following which the virus establishes a latent infection in trigeminal and dorsal root ganglia that lasts for the life of the individual. VZV subsequently reactivates, spontaneously or...

journal_title：Journal of neurovirology

authors： Kennedy PG,Cohrs RJ

更新日期：2010-11-01 00:00:00

abstract：:Here, we report a patient who developed diplopia secondary to a right cranial nerve III and IV palsy, as well as fever and headache. Cerebrospinal fluid analysis (CSF) showed high varicella-zoster virus (VZV)-DNA viral load (>300,000,000 copies/ml). VZV antibodies in CSF was ≥1:16. Diagnosis of neurological reactivati...

journal_title：Journal of neurovirology

authors： Del Borgo C,Belvisi V,Valli MB,Currà A,Pozzetto I,Sepe M,Mastroianni CM

更新日期：2017-08-01 00:00:00

abstract：:Human T-lymphotropic virus type 1 (HTLV-1) is associated with adult T cell leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HAM/TSP is an inflammatory disease of the spinal cord and clinically characterized by progressive spastic paraparesis, urinary incontinence, and mild sen...

journal_title：Journal of neurovirology

authors： Nozuma S,Kubota R,Jacobson S

更新日期：2020-10-01 00:00:00