The association between multiple sclerosis and infection with Epstein-Barr virus and retrovirus.

abstract：:In order to examine the effect of HTLV-I proviral load on the pathogenesis of HAM/TSP, we measured the HTLV-I proviral load in peripheral blood mononuclear cells (PBMC) from a large number of HAM/TSP patients and asymptomatic HTLV-I carriers. To measure the proviral load, we used an accurate and reproducible quantitat...

journal_title：Journal of neurovirology

authors： Nagai M,Usuku K,Matsumoto W,Kodama D,Takenouchi N,Moritoyo T,Hashiguchi S,Ichinose M,Bangham CR,Izumo S,Osame M

更新日期：1998-12-01 00:00:00

abstract：:In 2007, the nosology for HIV-1-associated neurocognitive disorders (HAND) was updated to a primarily neurocognitive disorder. However, currently available diagnostic tools lack the sensitivity and specificity needed for an accurate diagnosis for HAND. Scientists and clinicians, therefore, have been on a quest for an ...

journal_title：Journal of neurovirology

authors： McLaurin KA,Booze RM,Mactutus CF

更新日期：2019-10-01 00:00:00

abstract：:Amplification of viral nucleic acids from the cerebrospinal fluid (CSF) has considerably improved the diagnosis of several acute, subacute and chronic viral infections of the nervous system. In herpes simplex virus (HSV) encephalitis (HSE) the polymerase chain reaction (PCR) has become the method of choice for the rap...

journal_title：Journal of neurovirology

authors： Weber T,Frye S,Bodemer M,Otto M,Lüke W

更新日期：1996-06-01 00:00:00

abstract：:Our previous studies in an experimental model of rabies showed neuronal process degeneration in association with severe clinical disease. Cultured adult rodent dorsal root ganglion neurons infected with challenge virus standard (CVS)-11 strain of rabies virus (RABV) showed axonal swellings and reduced axonal growth wi...

journal_title：Journal of neurovirology

authors： Kammouni W,Wood H,Saleh A,Appolinario CM,Fernyhough P,Jackson AC

更新日期：2015-08-01 00:00:00

abstract：:We present the case of a 43-year-old-man with a past medical history of HIV with recently initiated HAART and existing PML that presented with altered mental status. The initial diagnosis was deemed to be PML-IRIS; however, neuroimaging brought into question this diagnosis. Flow cytometry performed from the cerebrospi...

journal_title：Journal of neurovirology

authors： Reddi A,Patel N,Morris NA

更新日期：2019-12-01 00:00:00

abstract：:Varicella-zoster virus (VZV) is a ubiquitous human herpes virus typically acquired in childhood when it causes varicella (chickenpox), following which the virus establishes a latent infection in trigeminal and dorsal root ganglia that lasts for the life of the individual. VZV subsequently reactivates, spontaneously or...

journal_title：Journal of neurovirology

authors： Kennedy PG,Cohrs RJ

更新日期：2010-11-01 00:00:00

abstract：:A significant number of human immunodeficiency virus type 1 (HIV-1)-infected patients are alcoholics. Either alcohol or HIV alone induces morphological and functional damage to the nervous system. HIV-1 Tat is a potent transcriptional activator of the viral promoter, with the ability to modulate a number of cellular r...

journal_title：Journal of neurovirology

authors： Brailoiu E,Brailoiu GC,Mameli G,Dolei A,Sawaya BE,Dun NJ

更新日期：2006-02-01 00:00:00

abstract：:Excessive glutamate neurotransmission has been implicated in neuronal injury in many disorders of the central nervous system (CNS), including human immunodeficiency virus (HIV)-associated dementia. Gp120IIIB is a strain of a HIV glycoprotein with specificity for the CXCR4 receptor that induces neuronal apoptosis in in...

journal_title：Journal of neurovirology

authors： Thomas AG,Bodner A,Ghadge G,Roos RP,Slusher BS

更新日期：2009-09-01 00:00:00

abstract：:In the era of the AIDS pandemic, progressive multifocal leukoencephalopathy (PML) has ceased being a rare disease. Prevalence estimates from clinical and pathological series suggest that up to 5% of all HIV-infected persons will develop PML. The extraordinary frequency with which PML attends HIV infection vastly excee...

journal_title：Journal of neurovirology

authors： Berger JR

更新日期：2003-01-01 00:00:00

abstract：:We present an immunocompetent patient with transverse myelitis (TM) during acute cytomegalovirus (CMV) infection, as evidenced by a reactive serum CMV IgM and CMV viremia. The patient had an excellent outcome after receiving only high-dose methylprednisolone. Given concerns that practitioners may have around the use o...

journal_title：Journal of neurovirology

authors： Budhram A,Liu Y,Krawczyk M,Chan TLH,Burneo JG,Hosseini-Moghaddam SM,Shoesmith C

更新日期：2019-06-01 00:00:00

abstract：:Research assessing whether major depressive disorders (MDD) impacts neurocognitive functions in HIV+ persons has yielded inconsistent results. However, none have considered the role of MDD remission, chronicity, and stability on treatment. Ninety-five HIV+ adults clinically stable on combined antiretroviral treatment ...

journal_title：Journal of neurovirology

authors： Cysique LA,Dermody N,Carr A,Brew BJ,Teesson M

更新日期：2016-02-01 00:00:00

abstract：:The presence of antibodies reactive with Borna disease virus (BDV) in the sera of some patients with certain psychiatric illnesses has been taken as evidence that this veterinary neurotrophic virus may occasionally infect and cause psychiatric disorders in humans. In this paper, we report the results of our studies co...

journal_title：Journal of neurovirology

authors： Richt JA,Alexander RC,Herzog S,Hooper DC,Kean R,Spitsin S,Bechter K,Schüttler R,Feldmann H,Heiske A,Fu ZF,Dietzschold B,Rott R,Koprowski H

更新日期：1997-04-01 00:00:00

abstract：:JC virus (JCV) is a human polyomavirus that exists in at least eight different genotypes as a result of coevolution with different human populations all over the world. Well adapted to its host, it usually persists in the kidneys and possibly the brain. If the host becomes immunodeficient, JCV can cause the fatal demy...

journal_title：Journal of neurovirology

authors： Eberwein P,Hansen LL,Agostini HT

更新日期：2005-02-01 00:00:00

abstract：:This single-center study attempts to quantify the incidence of symptomatic CSF viral escape (CSFVE) in patients receiving atazanavir/r (ATV/r)-containing regimen. We performed a retrospective analysis of patients receiving ATV/r-containing ART who were diagnosed with symptomatic CSFVE from August 2012 to January 2017....

journal_title：Journal of neurovirology

authors： Patel AK,Patel KK,Gohel S,Kumar A,Letendre S

更新日期：2018-08-01 00:00:00

abstract：:With aging of HIV populations, there is concern that Alzheimer's disease (AD) may become prevalent and difficult to distinguish from HIV-associated neurocognitive disorders. To date, there are no reports documenting histologically verified Alzheimer's neuropathology in individuals with HIV and dementia. Herein, we rep...

journal_title：Journal of neurovirology

authors： Morgello S,Jacobs M,Murray J,Byrd D,Neibart E,Mintz L,Meloni G,Chon C,Crary J

更新日期：2018-10-01 00:00:00

abstract：:Nipah virus is a recently emergent paramyxovirus that is capable of causing severe disease in both humans and animals. The first outbreak of Nipah virus occurred in Malaysia and Singapore in 1999 and, more recently, outbreaks were detected in Bangladesh. In humans, Nipah virus causes febrile encephalitis with respirat...

journal_title：Journal of neurovirology

authors： Bellini WJ,Harcourt BH,Bowden N,Rota PA

更新日期：2005-10-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) can frequently infect the central nervous system (CNS) in the setting of immunosuppression such as transplantation and infection with the human immunodeficiency virus (HIV). Our laboratory previously reported that HCMV infection of human brain aggregates preferentially infected a microglia...

journal_title：Journal of neurovirology

authors： Pulliam L,Moore D,West DC

更新日期：1995-06-01 00:00:00

abstract：:A method is described for amplification of the complete genome of the human polyomavirus JC (JCV) from progressive multifocal leukuencephalopathy (PML) brain, cerebrospinal fluid (CSF) of PML patients, and from the urine of controls without neurological disease. Efficient amplification with the 'long PCR' method is ac...

journal_title：Journal of neurovirology

authors： Agostini HT,Stoner GL

更新日期：1995-09-01 00:00:00

abstract：:Herpes simplex virus (HSV) latent infection of ganglion neurons follows axoplasmic transport of HSV, probably in the form of nucleocapsid from peripheral sites of infection (e.g. footpad). This raises the possibility that latency is dependent on this particular means of presenting HSV to ganglion neurons. To investiga...

journal_title：Journal of neurovirology

authors： Hay KA,Edris WA,Gaydos A,Tenser RB

更新日期：1998-10-01 00:00:00

abstract：:The neuromotor rehabilitative treatment should be joined in the global individualised project. The rehabilitation project is developed by an interdisciplinary. Hence, the clinicians have to promote an appropriate compensation process in the daily living activities with a rapid insertion of new or recovered motor-postu...

journal_title：Journal of neurovirology

authors： Cardini RG,Crippa AC,Cattaneo D

更新日期：2000-05-01 00:00:00

abstract：:Cytomegalovirus (CMV) infections are common and severe complications of HIV infection. The virus involves the nervous system, causing encephalitis, polyradiculomyelitis and peripheral neuropathies. Due to their limited sensitivity, traditional virological approaches, such as virus isolation or antigen detection in the...

journal_title：Journal of neurovirology

authors： Cinque P,Cleator GM,Weber T,Monteyne P,Sindic C,Gerna G,van Loon AM,Klapper PE

更新日期：1998-02-01 00:00:00

abstract：:HIV-associated neurocognitive disorders (HANDs) continue to be common and are associated with increased morbidity and mortality. However, the underlying mechanisms in the combination antiretroviral therapy (cART) era are not fully understood. Interferon alpha (IFNα) is an antiviral cytokine found to be elevated in the...

journal_title：Journal of neurovirology

authors： Anderson AM,Lennox JL,Mulligan MM,Loring DW,Zetterberg H,Blennow K,Kessing C,Koneru R,Easley K,Tyor WR

更新日期：2017-02-01 00:00:00

abstract：:Gliomas are the most frequent primary brain tumors in humans. Many studies have been carried out on their etiology; however, the only confirmed risk factors are hereditary predisposing conditions and high dose of ionizing radiation. Recently, human cytomegalovirus (HCMV) gene products and nucleic acids were reported t...

journal_title：Journal of neurovirology

authors： Poltermann S,Schlehofer B,Steindorf K,Schnitzler P,Geletneky K,Schlehofer JR

更新日期：2006-04-01 00:00:00

abstract：:Factors associated with HIV-associated neurocognitive disorders (HAND) include CD4(+) nadir and count, HIV RNA level, and HIV-1 subtype. Here, we investigated demographical and clinical markers with respect to HAND in a homogenous Chinese population. Individuals with HAND (global deficit score ≥0.5) had lower nadir (p...

journal_title：Journal of neurovirology

authors： Day TR,Smith DM,Heaton RK,Franklin D,Tilghman MW,Letendre S,Jin H,Wu Z,Shi C,Yu X,Pérez-Santiago J

更新日期：2016-04-01 00:00:00

abstract：:Enteroviruses are one of the most important causes of viral encephalitis in the neonatal period. However, the non-specificity of the symptoms presented renders its diagnosis challenging. Intracranial MRI has been reported to be a very useful imaging modality that can detect the characteristic white matter lesions arou...

journal_title：Journal of neurovirology

authors： Nakamura R,Chong PF,Haraguchi K,Katano H,Tanaka-Taya K,Kira R

更新日期：2020-10-01 00:00:00

abstract：:Zika virus (ZIKV) is an arbovirus transmitted mainly by mosquitos of Aedes species. The virus has emerged in recent years and spread throughout North and South Americas. The recent outbreak of ZIKV started in Brazil (2015) has resulted in infections surpassing a million mark. Contrary to the previous beliefs that Zika...

journal_title：Journal of neurovirology

authors： Koppolu V,Shantha Raju T

更新日期：2018-06-01 00:00:00

abstract：:The most common complication of zoster in the elderly is postherpetic neuralgia, operationally defined as pain persisting longer than 1-2 months after rash. The cause of postherpetic neuralgia is unknown. Using polymerase chain reaction, we detected varicella zoster virus DNA in blood mononuclear cells from 11 of 51 p...

journal_title：Journal of neurovirology

authors： Mahalingam R,Wellish M,Brucklier J,Gilden DH

更新日期：1995-03-01 00:00:00

abstract：:Everyday functioning (EF) impairment is frequent in people living with HIV (PLWH). Our aim was to better explore EF and its association with PLWH cognition, by administering both the IADL scale, the most common functional scale, and a new and ecologic multi-domain (communication and financial skills) tool to measure E...

journal_title：Journal of neurovirology

authors： Delle Donne V,Ciccarelli N,Massaroni V,Borghetti A,Dusina A,Farinacci D,Visconti E,Tamburrini E,Fabbiani M,Di Giambenedetto S

更新日期：2020-12-01 00:00:00

abstract：:HIV-associated neurocognitive disorder (HAND) is characterized by chronic immune activation. We aimed to identify biomarkers associated with HAND and to investigate their association with cognitive function and sex, in a homogenous cohort of HIV-infected (HIV+) young adults, parenterally infected during early childhoo...

journal_title：Journal of neurovirology

authors： Burlacu R,Umlauf A,Marcotte TD,Soontornniyomkij B,Diaconu CC,Bulacu-Talnariu A,Temereanca A,Ruta SM,Letendre S,Ene L,Achim CL

更新日期：2020-02-01 00:00:00

abstract：:Metabolic syndrome (MetS), a constellation of related metabolic risk factors, is a common comorbidity associated with cognitive difficulty in people living with HIV (PLWH). Neurobehavioral disturbances (e.g., behavioral manifestations of frontal-subcortical dysfunction) are also prevalent in HIV, yet the role MetS mig...

journal_title：Journal of neurovirology

authors： Pope CN,Montoya JL,Vasquez E,Pérez-Santiago J,Ellis R,McCutchan JA,Jeste DV,Moore DJ,Marquine MJ

更新日期：2020-12-01 00:00:00