Abstract:
:Enteroviruses are one of the most important causes of viral encephalitis in the neonatal period. However, the non-specificity of the symptoms presented renders its diagnosis challenging. Intracranial MRI has been reported to be a very useful imaging modality that can detect the characteristic white matter lesions around the periventricular regions. In this study, we report a case of a patient with neonatal encephalitis who presented with normal white blood cell counts in the initial cerebrospinal fluid analysis. A lumbar puncture retap identified pleocytosis, and polymerase chain reaction assays detected enterovirus 71 in the blood and stool samples. Furthermore, MRI revealed atypical disseminated cortical and subcortical white matter lesions on diffusion weighted images, and neuroradiological re-evaluation showed necrotic changes 2 weeks later. This unique case expands our knowledge of the spectrum of neurological disorders due to enterovirus 71 infection in neonatal period.
journal_name
J Neuroviroljournal_title
Journal of neurovirologyauthors
Nakamura R,Chong PF,Haraguchi K,Katano H,Tanaka-Taya K,Kira Rdoi
10.1007/s13365-020-00843-2subject
Has Abstractpub_date
2020-10-01 00:00:00pages
790-792issue
5eissn
1355-0284issn
1538-2443pii
10.1007/s13365-020-00843-2journal_volume
26pub_type
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