Abstract:
:We present an immunocompetent patient with transverse myelitis (TM) during acute cytomegalovirus (CMV) infection, as evidenced by a reactive serum CMV IgM and CMV viremia. The patient had an excellent outcome after receiving only high-dose methylprednisolone. Given concerns that practitioners may have around the use of immunosuppressive therapy for this potentially infectious myelopathy, we systematically reviewed the literature to assess outcomes after administration of high-dose corticosteroids to this population. Despite severe disease at clinical nadir with inability to ambulate, immunocompetent patients with acute CMV-associated TM who received high-dose corticosteroids had good clinical outcomes 1 month to 1 year after presentation.
journal_name
J Neuroviroljournal_title
Journal of neurovirologyauthors
Budhram A,Liu Y,Krawczyk M,Chan TLH,Burneo JG,Hosseini-Moghaddam SM,Shoesmith Cdoi
10.1007/s13365-018-0717-2subject
Has Abstractpub_date
2019-06-01 00:00:00pages
405-409issue
3eissn
1355-0284issn
1538-2443pii
10.1007/s13365-018-0717-2journal_volume
25pub_type
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