The recruitment of peripheral blood leukocytes to the brain is delayed in susceptible BALB/c compared to resistant C57BL/6 mice during herpes simplex virus encephalitis.

abstract：:Two human alpha-herpesviruses, herpes simplex virus (HSV)-1 and varicella zoster virus (VZV), account for the most frequent and serious neurologic disease caused by any of the eight human herpesviruses. Both HSV-1 and VZV become latent in ganglia. In this review, the authors describe features of latency for these viru...

journal_title：Journal of neurovirology

authors： Mitchell BM,Bloom DC,Cohrs RJ,Gilden DH,Kennedy PG

更新日期：2003-04-01 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) play important roles in regulating eukaryotic genome replication and gene expression in diverse biological systems. Here, we identified lncRNAs transcribed from pseudorabies virus (PRV)-infected PK-15 cells. Based on high-throughput sequencing data, we obtained 87,263,926 and 93,947,628 c...

journal_title：Journal of neurovirology

authors： Guan X,Liu J,Jiang H,Wu CX,Chen HC,Liu ZF

更新日期：2018-10-01 00:00:00

abstract：:Acute hemorrhagic leukoencephalitis (AHL) is a rare and usually fatal disorder characterized clinically by an acute onset of neurologic abnormalities. It may occur in association with a viral illness or vaccination. Radiology and brain biopsy are essential for the diagnosis. The etiology of AHL is unclear. We postulat...

journal_title：Journal of neurovirology

authors： An SF,Groves M,Martinian L,Kuo LT,Scaravilli F

更新日期：2002-10-01 00:00:00

abstract：:Flavivirus encephalitis is believed to be the result of two main mechanisms: (i) direct damage to and dysfunction of neurons as a result of viral replication and (ii) destruction of the brain tissue by an inflammatory response. The differential impact of both mechanisms on the progression of flavivirus encephalitis ha...

journal_title：Journal of neurovirology

authors： Leyssen P,Paeshuyse J,Charlier N,Van Lommel A,Drosten C,De Clercq E,Neyts J

更新日期：2003-02-01 00:00:00

abstract：:Toscana virus (Bunyaviridae family, Phlebovirus genus) is a sandfly fever virus responsible for human neurological infections. Sandfly viruses are transmitted by insect vectors (Phlebotomus species) and the infection is present in climatic areas that allow the life cycle of the vector. The arthropode-borne Toscana vir...

journal_title：Journal of neurovirology

authors： Valassina M,Cusi MG,Valensin PE

更新日期：2003-12-01 00:00:00

abstract：:This mini-review summarizes current knowledge of MSRV (multiple sclerosis-associated retrovirus), founder member of the type W family of human endogenous retroviruses (HERVs), its pathogenic potential and association with diseases. As retrotransposable elements, HERVs behave differently from stable genes, and cannot b...

journal_title：Journal of neurovirology

authors： Dolei A,Perron H

更新日期：2009-01-01 00:00:00

abstract：:Human herpesvirus-6, the etiologic agent of exanthem subitum, is a ubiquitous virus that infects almost all children by the age of 2 years and that has previously been shown to be neuroinvasive. These characteristics suggest that human herpesvirus-6 may be important in the neuropathogenesis of acquired immune deficien...

journal_title：Journal of neurovirology

authors： Saito Y,Sharer LR,Dewhurst S,Blumberg BM,Hall CB,Epstein LG

更新日期：1995-03-01 00:00:00

abstract：:HIV-1 viral proteins have been implicated in endothelial dysfunction, which is a major determinant of ischaemic stroke risk in HIV-infected individuals. Polymorphisms in HIV-1 viral protein R (Vpr) may alter its potential to promote endothelial dysfunction, by modifying its effects on viral replication, reactivation o...

journal_title：Journal of neurovirology

authors： McMullen K,Bateman K,Stanley A,Combrinck M,Engelbrecht S,Bryer A

更新日期：2021-01-18 00:00:00

abstract：:In May 2012, the Division of AIDS Research at the National Institute of Mental Health (NIMH) organized the "Global NeuroAIDS Roundtable" in conjunction with the 11th International Symposium on Neurovirology and the 2012 Conference on HIV in the Nervous System. The meeting was held in New York, NY, USA and brought toge...

journal_title：Journal of neurovirology

authors： Joseph J,Achim CL,Boivin MJ,Brew BJ,Clifford DB,Colosi DA,Ellis RJ,Heaton RK,Gallo-Diop A,Grant I,Kanmogne GD,Kumar M,Letendre S,Marcotte TD,Nath A,Pardo CA,Paul RH,Pulliam L,Robertson K,Royal W 3rd,Sacktor N,Si

更新日期：2013-02-01 00:00:00

abstract：:Epidemiological studies have indicated an association between influenza A virus infections during fetal life and neuropsychiatric diseases. To study the potential for influenza A virus infections to cause nervous system dysfunctions, we describe a mouse model using intranasal instillation of the mouse neuroadapted inf...

journal_title：Journal of neurovirology

authors： Aronsson F,Lannebo C,Paucar M,Brask J,Kristensson K,Karlsson H

更新日期：2002-08-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1)-associated neuropathogenesis occurs in a large minority of infected people. Presently, there are neither viral nor cellular markers that predict the development of brain disease during HIV-1 infection. This study was conducted to determine whether there exist systematic diff...

journal_title：Journal of neurovirology

authors： Kazmierczak K,Potash MJ

更新日期：2007-10-01 00:00:00

abstract：:Interferon-inducible expression of major histocompatibility class I genes has previously been found to be quantitatively and functionally deficient in neurons compared to other somatic cells or other neural cell types including astrocytes. This deficiency is a key component of neuronal immunoprivilege during viral inf...

journal_title：Journal of neurovirology

authors： Massa PT,Whitney LW,Wu C,Ropka SL,Jarosinski KW

更新日期：1999-04-01 00:00:00

abstract：:Although HIV-associated dementia (HAD) occurs in less than 5 % of individuals with access to combination antiretroviral therapy, rates of milder forms of HIV-associated neurocognitive disorder (HAND) are much higher. We sought to define an optimal cut point for the International HIV Dementia Scale (IHDS) in Thailand f...

journal_title：Journal of neurovirology

authors： Chalermchai T,Valcour V,Sithinamsuwan P,Pinyakorn S,Clifford D,Paul RH,Tipsuk S,Fletcher JL,Degruttola V,Ratto-Kim S,Hutchings N,Shikuma C,Ananworanich J,SEARCH 007 and 011 study groups.

更新日期：2013-04-01 00:00:00

abstract：:Cytomegalovirus (CMV) infections are common and severe complications of HIV infection. The virus involves the nervous system, causing encephalitis, polyradiculomyelitis and peripheral neuropathies. Due to their limited sensitivity, traditional virological approaches, such as virus isolation or antigen detection in the...

journal_title：Journal of neurovirology

authors： Cinque P,Cleator GM,Weber T,Monteyne P,Sindic C,Gerna G,van Loon AM,Klapper PE

更新日期：1998-02-01 00:00:00

abstract：:We examined murine hepatitis virus strain A59 (MHV-A59)-induced demyelinating disease in C57BL/6 mice which had previously been thymectomized at 25 days of age. Demyelination was observed in 51-96% of spinal cord quadrants examined 30 or 60 days post infection (dpi), indicating that neither an intact thymus nor thymic...

journal_title：Journal of neurovirology

authors： Sutherland RM,Chua MM,Lavi E,Weiss SR,Paterson Y

更新日期：1997-06-01 00:00:00

abstract：:The article "Progressive multifocal leukoencephalopathy in rituximab-treated rheumatic diseases: a rare event," written by Joseph R. Berger, Vineeta Malik, Stuart Lacey, Paul Brunetta, and Patricia B. Lehane3, was originally published electronically on the publisher's internet portal (currently SpringerLink). ...

journal_title：Journal of neurovirology

authors： Berger JR,Malik V,Lacey S,Brunetta P,Lehane PB

更新日期：2018-06-01 00:00:00

abstract：:Enteroviruses are one of the most important causes of viral encephalitis in the neonatal period. However, the non-specificity of the symptoms presented renders its diagnosis challenging. Intracranial MRI has been reported to be a very useful imaging modality that can detect the characteristic white matter lesions arou...

journal_title：Journal of neurovirology

authors： Nakamura R,Chong PF,Haraguchi K,Katano H,Tanaka-Taya K,Kira R

更新日期：2020-10-01 00:00:00

abstract：:Murine hepatitis virus A59 infection of the central nervous system (CNS) results in CNS demyelination in susceptible strains of mice. In infected B-cell-deficient mice, demyelination not only occurred but was also more severe than in parental C57BL/6 animals. This increase may be due to the persistence of virus in the...

journal_title：Journal of neurovirology

authors： Matthews AE,Lavi E,Weiss SR,Paterson Y

更新日期：2002-06-01 00:00:00

abstract：:A number of pathogenic microbes including neuroinvasive viruses, bacteria and parasites are capable of entry into the central nervous system (CNS) and cause a variety of clinical manifestations. The cellular and molecular mechanisms for the CNS invasion have been extensively studied in the last two decades. Viruses in...

journal_title：Journal of neurovirology

authors： Zhang JR,Tuomanen E

更新日期：1999-12-01 00:00:00

abstract：:Theiler's murine encephalomyelitis virus (TMEV) infects the central nervous system of mice and causes a demyelinating disease that is a model for multiple sclerosis. During the chronic phase of the disease, TMEV persists in oligodendrocytes and macrophages. Lack of remyelination has been attributed to insufficient pro...

journal_title：Journal of neurovirology

authors： Benner B,Martorell AJ,Mahadevan P,Najm FJ,Tesar PJ,Freundt EC

更新日期：2016-06-01 00:00:00

abstract：:Herpes simplex encephalitis relapses have been rarely reported, with only few cases occurring after neurosurgical interventions. A young man presented a late herpes simplex encephalitis relapse after left antero-mesial temporal resection for his refractory temporal lobe epilepsy. Eight days after surgery, he developed...

journal_title：Journal of neurovirology

authors： Mantero V,Cossu M,Rigamonti A,Fiumani A,Basilico P,Tassi L,Salmaggi A

更新日期：2020-02-01 00:00:00

abstract：:Previous animal studies have identified a C31S residue substitution in the C30C31 dicysteine motif of the Tat protein that is associated with reduced neurovirulence in clade C human immunodeficiency virus (HIV). However, clinical studies of patients infected with clade C HIV have reported significant levels of cogniti...

journal_title：Journal of neurovirology

authors： Paul RH,Joska JA,Woods C,Seedat S,Engelbrecht S,Hoare J,Heaps J,Valcour V,Ances B,Baker LM,Salminen LE,Stein DJ

更新日期：2014-12-01 00:00:00

abstract：:JC virus (JCV) is a human polyomavirus that exists in at least eight different genotypes as a result of coevolution with different human populations all over the world. Well adapted to its host, it usually persists in the kidneys and possibly the brain. If the host becomes immunodeficient, JCV can cause the fatal demy...

journal_title：Journal of neurovirology

authors： Eberwein P,Hansen LL,Agostini HT

更新日期：2005-02-01 00:00:00

abstract：:The flaviviruses dengue, West Nile, and Japanese encephalitis represent three major mosquito-borne viruses worldwide. These pathogens impact the lives of millions of individuals and potentially could affect non-endemic areas already colonized by mosquito vectors. Unintentional transport of infected vectors (Aedes and ...

journal_title：Journal of neurovirology

authors： Daep CA,Muñoz-Jordán JL,Eugenin EA

更新日期：2014-12-01 00:00:00

abstract：:Research assessing whether major depressive disorders (MDD) impacts neurocognitive functions in HIV+ persons has yielded inconsistent results. However, none have considered the role of MDD remission, chronicity, and stability on treatment. Ninety-five HIV+ adults clinically stable on combined antiretroviral treatment ...

journal_title：Journal of neurovirology

authors： Cysique LA,Dermody N,Carr A,Brew BJ,Teesson M

更新日期：2016-02-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease affecting the central nervous system as a result of reactivation of the John Cunningham (JC) polyomavirus and occurs almost exclusively in immunosuppressed individuals. The disease course of PML is variable but usually progressive and often fa...

journal_title：Journal of neurovirology

authors： Holmes A,Wellings T,Walsh O,Rowlings P

更新日期：2020-12-01 00:00:00

abstract：:Although no longer considered therapeutically beneficial, antiretroviral treatment interruptions (TIs) still occur frequently among patients with human immunodeficiency virus (HIV) infection for a variety of reasons. TIs typically result in viral rebound and worsening immunosuppression, which in turn are risk factors ...

journal_title：Journal of neurovirology

authors： Childers ME,Woods SP,Letendre S,McCutchan JA,Rosario D,Grant I,Mindt MR,Ellis RJ,San Diego HIV Neurobehavioral Research Center Group.

更新日期：2008-11-01 00:00:00

abstract：:Pseudorabies virus (PRV) primarily infects swine but can infect cattle, dogs, and cats. Several studies have reported that PRV can cross the specie barrier and induce human encephalitis, but a definitive diagnosis of human PRV encephalitis is debatable due to the lack of PRV DNA detection. Here, we report a case of hu...

journal_title：Journal of neurovirology

authors： Wang D,Tao X,Fei M,Chen J,Guo W,Li P,Wang J

更新日期：2020-06-01 00:00:00

abstract：:Like human immunodeficiency virus (HIV), feline immunodeficiency virus (FIV) invades and infects the central nervous system (CNS) soon after peripheral infection. The appearance of viral RNA is particularly prominent in the cerebrospinal fluid (CSF), suggesting an efficient route of virus transfer across the blood-CSF...

journal_title：Journal of neurovirology

authors： Liu P,Hudson LC,Tompkins MB,Vahlenkamp TW,Colby B,Rundle C,Meeker RB

更新日期：2006-08-01 00:00:00

abstract：:Neurocognitive impairment (NCI) among HIV-infected patients is heterogeneous in its reported presentations and frequencies. To determine the prevalence of NCI and its associated subtypes as well as predictive variables, we investigated patients with HIV/AIDS receiving universal health care. Recruited adult HIV-infecte...

journal_title：Journal of neurovirology

authors： Tu W,Chen PA,Koenig N,Gomez D,Fujiwara E,Gill MJ,Kong L,Power C

更新日期：2020-02-01 00:00:00