Neurologic dysfunctions caused by a molecular clone of feline immunodeficiency virus, FIV-PPR.

abstract：:Excessive glutamate neurotransmission has been implicated in neuronal injury in many disorders of the central nervous system (CNS), including human immunodeficiency virus (HIV)-associated dementia. Gp120IIIB is a strain of a HIV glycoprotein with specificity for the CXCR4 receptor that induces neuronal apoptosis in in...

journal_title：Journal of neurovirology

authors： Thomas AG,Bodner A,Ghadge G,Roos RP,Slusher BS

更新日期：2009-09-01 00:00:00

abstract：:A neuroinvasive/neuropathogenic SIV variant termed SIVmac182 was previously isolated and characterized (Watry et al, 1994). This neuroinvasive strain was derived from the uncloned strain SIVmac251 through serial animal passage of infected microglia, unlike previously reported neurovirulent strains. Importantly, the vi...

journal_title：Journal of neurovirology

authors： Strelow LI,Watry DD,Fox HS,Nelson JA

更新日期：1998-06-01 00:00:00

abstract：:The brain's intrinsic immune system consists of glial cells that produce cytokines and chemokines in response to stimulation with cytomegalovirus (CMV). The present experiments were undertaken to determine whether this intrinsic glial cell response alone is sufficient to control CMV infection of the central nervous sy...

journal_title：Journal of neurovirology

authors： Cheeran MC,Gekker G,Hu S,Min X,Cox D,Lokensgard JR

更新日期：2004-06-01 00:00:00

abstract：:We present the case of a 43-year-old-man with a past medical history of HIV with recently initiated HAART and existing PML that presented with altered mental status. The initial diagnosis was deemed to be PML-IRIS; however, neuroimaging brought into question this diagnosis. Flow cytometry performed from the cerebrospi...

journal_title：Journal of neurovirology

authors： Reddi A,Patel N,Morris NA

更新日期：2019-12-01 00:00:00

abstract：:The neurological manifestations of HIV infection may be in part due to alterations in the blood-brain barrier. These may be caused by structural changes in the barrier or may consist of subtle metabolic or biochemical disturbances in barrier function. In the CNS, the family of glucose transporter proteins plays a key ...

journal_title：Journal of neurovirology

authors： Mankowski JL,Queen SE,Kirstein LM,Spelman JP,Laterra J,Simpson IA,Adams RJ,Clements JE,Zink MC

更新日期：1999-12-01 00:00:00

abstract：:Murine hepatitis virus A59 infection of the central nervous system (CNS) results in CNS demyelination in susceptible strains of mice. In infected B-cell-deficient mice, demyelination not only occurred but was also more severe than in parental C57BL/6 animals. This increase may be due to the persistence of virus in the...

journal_title：Journal of neurovirology

authors： Matthews AE,Lavi E,Weiss SR,Paterson Y

更新日期：2002-06-01 00:00:00

abstract：:HIV-associated neurocognitive disorder (HAND) is characterized by chronic immune activation. We aimed to identify biomarkers associated with HAND and to investigate their association with cognitive function and sex, in a homogenous cohort of HIV-infected (HIV+) young adults, parenterally infected during early childhoo...

journal_title：Journal of neurovirology

authors： Burlacu R,Umlauf A,Marcotte TD,Soontornniyomkij B,Diaconu CC,Bulacu-Talnariu A,Temereanca A,Ruta SM,Letendre S,Ene L,Achim CL

更新日期：2020-02-01 00:00:00

abstract：:The aim of this study was to review the quality of the diagnostic work-up for acute encephalitis carried out at our center in a cohort of patients with hematological disorders. Our data showed substantial heterogeneity in investigating patients. Not all patients had their CSF tested for viruses commonly responsible fo...

journal_title：Journal of neurovirology

authors： Vegezzi E,Berzero G,Barbetta D,Colombo AA,Borsani O,Bernasconi P,Compagno F,Zecca M,Campanini G,Simoncelli A,Paoletti M,Pichiecchio A,Baldanti F,Brunetti E,Marchioni E

更新日期：2020-04-01 00:00:00

abstract：:HIV-associated neurocognitive disorders (HAND) continues to be prevalent (30-50%) despite plasma HIV-RNA suppression with combination antiretroviral therapy (cART). There is no proven therapy for individuals on suppressive cART with HAND. We have shown that the degree of HIV reservoir burden (HIV DNA) in monocytes app...

journal_title：Journal of neurovirology

authors： Ndhlovu LC,Umaki T,Chew GM,Chow DC,Agsalda M,Kallianpur KJ,Paul R,Zhang G,Ho E,Hanks N,Nakamoto B,Shiramizu BT,Shikuma CM

更新日期：2014-12-01 00:00:00

abstract：:We present an immunocompetent patient with transverse myelitis (TM) during acute cytomegalovirus (CMV) infection, as evidenced by a reactive serum CMV IgM and CMV viremia. The patient had an excellent outcome after receiving only high-dose methylprednisolone. Given concerns that practitioners may have around the use o...

journal_title：Journal of neurovirology

authors： Budhram A,Liu Y,Krawczyk M,Chan TLH,Burneo JG,Hosseini-Moghaddam SM,Shoesmith C

更新日期：2019-06-01 00:00:00

abstract：:A pandemic due to novel coronavirus arose in mid-December 2019 in Wuhan, China, and in 3 months' time swept the world. The disease has been referred to as COVID-19, and the causative agent has been labelled SARS-CoV-2 due to its genetic similarities to the virus (SARS-CoV-1) responsible for the severe acute respirator...

journal_title：Journal of neurovirology

authors： Berger JR

更新日期：2020-04-01 00:00:00

abstract：:Infection with human immunodeficiency virus-1 (HIV-1), the causative agent of acquired immunodeficiency syndrome (AIDS) in humans, causes a spectrum of neuropathology that includes alterations in behavior, changes in evoked potentials, and neuronal degeneration. In the simian immunodeficiency virus (SIV) model of HIV ...

journal_title：Journal of neurovirology

authors： Marcario JK,Manaye KF,SantaCruz KS,Mouton PR,Berman NE,Cheney PD

更新日期：2004-12-01 00:00:00

abstract：:Crack cocaine use is associated with impaired verbal memory in HIV-infected women more than uninfected women. To understand the neural basis for this impairment, this study examined the effects of crack cocaine use on activation of the prefrontal cortex (PFC) and strategic encoding during a verbal memory task in HIV-i...

journal_title：Journal of neurovirology

authors： Meyer VJ,Little DM,Fitzgerald DA,Sundermann EE,Rubin LH,Martin EM,Weber KM,Cohen MH,Maki PM

更新日期：2014-08-01 00:00:00

abstract：:Although animal parvoviruses have long been recognized as causes of brain pathology in multiple animal models, especially during early development, human parvoviruses are rarely thought of as neurotropic or causes of neuropathology in humans. However, several recent case reports have suggested possible associations of...

journal_title：Journal of neurovirology

authors： Hobbs JA

更新日期：2006-06-01 00:00:00

abstract：:To investigate the molecular basis for measles virus persistence in patients with subacute sclerosing panencephalitis (SSPE), the authors used a high-density oligonucleotide microarray, and found that the expression of granulysin in peripheral blood mononuclear cells was significantly lower in the patients than in the...

journal_title：Journal of neurovirology

authors： Takemoto M,Kira R,Kusuhara K,Torisu H,Sakai Y,Hara T

更新日期：2005-07-01 00:00:00

abstract：:Activated murine cytotoxic T cells express the NKG2D natural cytotoxicity receptor. This receptor recognizes major histocompatibility complex (MHC) class I-like molecules expressed on the surface of infected cells and serves to augment T cell-mediated cytotoxicity. The role of NKG2D-mediated augmentation in the cleara...

journal_title：Journal of neurovirology

authors： Deb C,Howe CL

更新日期：2008-05-01 00:00:00

abstract：:A subset of patients with coronavirus 2 disease (COVID-19) experience neurological complications. These complications include loss of sense of taste and smell, stroke, delirium, and neuromuscular signs and symptoms. The etiological agent of COVID-19 is SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), an R...

journal_title：Journal of neurovirology

authors： Azizi SA,Azizi SA

更新日期：2020-10-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease affecting the central nervous system as a result of reactivation of the John Cunningham (JC) polyomavirus and occurs almost exclusively in immunosuppressed individuals. The disease course of PML is variable but usually progressive and often fa...

journal_title：Journal of neurovirology

authors： Holmes A,Wellings T,Walsh O,Rowlings P

更新日期：2020-12-01 00:00:00

abstract：:An elevated human T cell leukemia virus type 1 (HTLV-1) proviral load (PVL) is an important risk factor for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), although there is a considerable frequency of asymptomatic carriers (AC) with high PVL in blood. Our objective was to evaluate whether PVL qua...

journal_title：Journal of neurovirology

authors： Martins ML,de Freitas Carneiro-Proietti AB,Nicolato R,de Miranda DM,Romanelli LCF

更新日期：2018-08-01 00:00:00

abstract：:Over the last 10 - 15 years, magnetic resonance imaging techniques have had a major impact in understanding and managing multiple sclerosis. The present review briefly summarises the current usefulness of spinal cord MRI in MS disease, examining the frequency, distribution and main characteristics of spine MS plaques;...

journal_title：Journal of neurovirology

authors： Bastianello S,Paolillo A,Giugni E,Giuliani S,Evangelisti G,Luccichenti G,Angeloni U,Colonnese C,Salvetti M,Gasperini C,Pozzilli C,Fieschi C

更新日期：2000-05-01 00:00:00

abstract：:After uniocular anterior chamber (AC) inoculation of herpes simplex virus type 1 (HSV-1), virus and TNF alpha (TNF-alpha) are detected in the suprachiasmatic nuclei (SCN). The goal of this study was to investigate the role of TNF-alpha and macrophages in the brain of HSV-1-infected BALB/c mice. Mice were treated with ...

journal_title：Journal of neurovirology

authors： Fields M,Zheng M,Zhang M,Atherton SS

更新日期：2006-12-01 00:00:00

abstract：:Viral oncolytic therapy for malignant brain tumors involves local intratumoral delivery of a genetically engineered virus with tumor cell-specific lytic activity. Promising preliminary results have been achieved in preclinical models with G207, a replication-competent herpes simplex virus type 1 constructed with multi...

journal_title：Journal of neurovirology

authors： Radbill AE,Reddy AT,Markert JM,Wyss JM,Pike MM,Akella NS,Bharara N,Gillespie GY

更新日期：2007-04-01 00:00:00

abstract：:There is controversy with regard to the entry pathway of the rabies virus (RABV) into the central nervous system (CNS). Some authors have suggested that the virus inoculated at the periphery is captured and transported to CNS only by motor neurons; however, it has been reported that dorsal root ganglia (DRG) sensory n...

journal_title：Journal of neurovirology

authors： Velandia-Romero ML,Castellanos JE,Martínez-Gutiérrez M

更新日期：2013-08-20 00:00:00

abstract：:Therapy for progressive multifocal leukoencephalopathy (PML) remains challenging since there are no antiviral therapies available for JC virus. Immune reconstitution has improved the prognosis in many settings where PML occurs, but it often is not possible in PML patients with hematologic malignancies. We describe the...

journal_title：Journal of neurovirology

authors： Hoang E,Bartlett NL,Goyal MS,Schmidt RE,Clifford DB

更新日期：2019-04-01 00:00:00

abstract：:HIV-1 infection results in a dementing illness affecting 20% of patients with AIDS. Several HIV-1 genes have been implicated in the pathogenesis of HIV-induced neurological disease. To search for distinct HIV-1 sequences associated with the development of dementia, brain-derived tat, env, and pol sequences were examin...

journal_title：Journal of neurovirology

authors： Bratanich AC,Liu C,McArthur JC,Fudyk T,Glass JD,Mittoo S,Klassen GA,Power C

更新日期：1998-08-01 00:00:00

abstract：:In May 2012, the Division of AIDS Research at the National Institute of Mental Health (NIMH) organized the "Global NeuroAIDS Roundtable" in conjunction with the 11th International Symposium on Neurovirology and the 2012 Conference on HIV in the Nervous System. The meeting was held in New York, NY, USA and brought toge...

journal_title：Journal of neurovirology

authors： Joseph J,Achim CL,Boivin MJ,Brew BJ,Clifford DB,Colosi DA,Ellis RJ,Heaton RK,Gallo-Diop A,Grant I,Kanmogne GD,Kumar M,Letendre S,Marcotte TD,Nath A,Pardo CA,Paul RH,Pulliam L,Robertson K,Royal W 3rd,Sacktor N,Si

更新日期：2013-02-01 00:00:00

abstract：:A postmarketing surveillance study was undertaken to investigate the safety and efficacy of interferon-alpha for human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy (HAM) under routine treatment conditions. A total of 273 cases from 91 medical institutions were registered into the survey. So far, 167...

journal_title：Journal of neurovirology

authors： Arimura K,Nakagawa M,Izumo S,Usuku K,Itoyama Y,Kira J,Osame M

更新日期：2007-08-01 00:00:00

abstract：:Many major physiological changes occur within the rodent central nervous system (CNS) during the first few postnatal weeks. These include axonogenesis, synaptogenesis and myelination. Concomitant with CNS development over this period, there is a decrease in susceptibility to many neurotropic virus infections in that i...

journal_title：Journal of neurovirology

authors： Oliver KR,Scallan MF,Dyson H,Fazakerley JK

更新日期：1997-02-01 00:00:00

abstract：:Epstein-Barr virus-specific CD4+ T cells could be involved in the pathogenesis of multiple sclerosis, provided they can gain entry to the intrathecal compartment. The authors have previously demonstrated that cerebrospinal fluid T cells from multiple sclerosis patients recognize autologous Epstein-Barr virus-transform...

journal_title：Journal of neurovirology

authors： Holmøy T,Kvale EØ,Vartdal F

更新日期：2004-10-01 00:00:00

abstract：:The neuromotor rehabilitative treatment should be joined in the global individualised project. The rehabilitation project is developed by an interdisciplinary. Hence, the clinicians have to promote an appropriate compensation process in the daily living activities with a rapid insertion of new or recovered motor-postu...

journal_title：Journal of neurovirology

authors： Cardini RG,Crippa AC,Cattaneo D

更新日期：2000-05-01 00:00:00