Diagnosing acute encephalitis in patients with hematological disorders: caveats and pitfalls.

abstract：:Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by the neurotropic human polyomavirus JC (JCV) lytic infection of oligodendrocytes. PML was first described as a complication of lymphoproliferative disorders more than 50 years ago and emerged as a major c...

journal_title：Journal of neurovirology

authors： Bellizzi A,Nardis C,Anzivino E,Rodìo D,Fioriti D,Mischitelli M,Chiarini F,Pietropaolo V

更新日期：2012-02-01 00:00:00

abstract：:The article "Progressive multifocal leukoencephalopathy in rituximab-treated rheumatic diseases: a rare event," written by Joseph R. Berger, Vineeta Malik, Stuart Lacey, Paul Brunetta, and Patricia B. Lehane3, was originally published electronically on the publisher's internet portal (currently SpringerLink). ...

journal_title：Journal of neurovirology

authors： Berger JR,Malik V,Lacey S,Brunetta P,Lehane PB

更新日期：2018-06-01 00:00:00

abstract：:Herpes simplex virus 1 meningo-encephalitis was ascertained in a 63-year-old immunocompetent man. To determine the duration of the persistence of herpesvirus DNA in the central nervous system, the cerebrospinal fluid was periodically monitored by polymerase chain reaction for 53 days. In addition to HSV-1, Epstein-Bar...

journal_title：Journal of neurovirology

authors： Portolani M,Sabbatini AM,Meacci M,Pietrosemoli P,Cermelli C,Lunghi P,Golinelli F,Stacca R

更新日期：1998-08-01 00:00:00

abstract：:Amplification of viral nucleic acids from the cerebrospinal fluid (CSF) has considerably improved the diagnosis of several acute, subacute and chronic viral infections of the nervous system. In herpes simplex virus (HSV) encephalitis (HSE) the polymerase chain reaction (PCR) has become the method of choice for the rap...

journal_title：Journal of neurovirology

authors： Weber T,Frye S,Bodemer M,Otto M,Lüke W

更新日期：1996-06-01 00:00:00

abstract：:We present two cases of recurrent progressive multifocal leukoencephalopathy (PML) in patients with long standing virally suppressed human immunodeficiency virus (HIV) and normal CD4+ T cell count who were taking stable regimens of highly active antiretroviral therapy (HAART). This has significant implications for oth...

journal_title：Journal of neurovirology

authors： Crossley KM,Agnihotri S,Chaganti J,Rodriguez ML,McNally LP,Venna N,Turbett SE,Gutman M,Morey A,Koralnik IJ,Brew BJ

更新日期：2016-08-01 00:00:00

abstract：:Gliomas are the most frequent primary brain tumors in humans. Many studies have been carried out on their etiology; however, the only confirmed risk factors are hereditary predisposing conditions and high dose of ionizing radiation. Recently, human cytomegalovirus (HCMV) gene products and nucleic acids were reported t...

journal_title：Journal of neurovirology

authors： Poltermann S,Schlehofer B,Steindorf K,Schnitzler P,Geletneky K,Schlehofer JR

更新日期：2006-04-01 00:00:00

abstract：:A neuroinvasive/neuropathogenic SIV variant termed SIVmac182 was previously isolated and characterized (Watry et al, 1994). This neuroinvasive strain was derived from the uncloned strain SIVmac251 through serial animal passage of infected microglia, unlike previously reported neurovirulent strains. Importantly, the vi...

journal_title：Journal of neurovirology

authors： Strelow LI,Watry DD,Fox HS,Nelson JA

更新日期：1998-06-01 00:00:00

abstract：:Bovine herpesvirus type 5 (BoHV-5) is the causative agent of herpetic meningoencephalitis in cattle. The purinergic system is described as a modulator of the immune response and neuroinflammation. These functions are related to the extracellular nucleotides concentration. NTPDase and 5'-nucleotidase are enzymes respon...

journal_title：Journal of neurovirology

authors： da Silva CB,Paim FC,Wolkmer P,Abdalla FH,Carvalho FB,Palma HH,Mello CB,Flores EF,Andrade CM,Lopes ST

更新日期：2015-10-01 00:00:00

abstract：:In 2007, the nosology for HIV-1-associated neurocognitive disorders (HAND) was updated to a primarily neurocognitive disorder. However, currently available diagnostic tools lack the sensitivity and specificity needed for an accurate diagnosis for HAND. Scientists and clinicians, therefore, have been on a quest for an ...

journal_title：Journal of neurovirology

authors： McLaurin KA,Booze RM,Mactutus CF

更新日期：2019-10-01 00:00:00

abstract：:HIV viral proteins within the central nervous system are associated with the development of neurocognitive impairments in HIV-infected individuals. Dopamine transporter (DAT)-mediated dopamine transport is critical for normal dopamine homeostasis. Abnormal dopaminergic transmission has been implicated as a risk determ...

journal_title：Journal of neurovirology

authors： Zhu J,Yuan Y,Midde NM,Gomez AM,Sun WL,Quizon PM,Zhan CG

更新日期：2016-06-01 00:00:00

abstract：:Most immunosuppressed individuals who develop progressive multifocal leukoencephalopathy (PML) have a rapid fatal outcome, whereas some become long-term survivors. We explored the impact of the cellular immune response against JC virus (JCV) on the clinical outcome of 7 HIV+ and 3 HIV- individuals with PML. Of the 4 H...

journal_title：Journal of neurovirology

authors： Du Pasquier RA,Clark KW,Smith PS,Joseph JT,Mazullo JM,De Girolami U,Letvin NL,Koralnik IJ

更新日期：2001-08-01 00:00:00

abstract：:Epstein-Barr virus (EBV) associated central nervous system (CNS) infection is a rare disease. We report an atypical manifestation of EBV encephalitis initially presenting with a tumor-like lesion of the optic tract in an immunocompromised patient 8 years after a combined kidney and pancreas transplantation had been pe...

journal_title：Journal of neurovirology

authors： Khalil M,Enzinger C,Wallner-Blazek M,Scarpatetti M,Barth A,Horn S,Reiter G

更新日期：2008-11-01 00:00:00

abstract：:A study of neuropsychological performance was conducted in 33 HIV+ patients initiating highly active antiretroviral therapy (HAART). Grooved Pegboard (GP) non-dominant hand performance improved in 23/33 (70%) subjects (P=0.002). Among 23 patients with motor slowing (GP non-dominant hand z score < -1.0) at baseline, 18...

journal_title：Journal of neurovirology

authors： Sacktor NC,Skolasky RL,Lyles RH,Esposito D,Selnes OA,McArthur JC

更新日期：2000-02-01 00:00:00

abstract：:The objective of this study is to describe the chronic pain characteristics in individuals infected with human T cell lymphotropic virus type 1 (HTLV-1) per subgroup (asymptomatic, oligosymptomatic, and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)) compared with controls with chronic pain withou...

journal_title：Journal of neurovirology

authors： Dos Santos DN,Sá KN,Queirós FC,Paixão AB,Santos KOB,de Andrade RCP,Camatti JR,Baptista AF

更新日期：2021-01-06 00:00:00

abstract：:We describe a 41-year-old patient, who upon receiving a bone marrow transplant in order to treat chronic myeloid leukemia, developed cytomegalovirus (CNV) retinitis and encephalitis under the ganciclovir maintenance treatment. Analysis of sequential viral isolates recovered from the patient's cerebrospinal fluid and b...

journal_title：Journal of neurovirology

authors： Arslan F,Tabak F,Avşar E,Midilli K,Mert A,Ozaras R,Soysal T,Ozturk R,Ferhanoglu B

更新日期：2010-03-01 00:00:00

abstract：:Here, we report a patient who developed diplopia secondary to a right cranial nerve III and IV palsy, as well as fever and headache. Cerebrospinal fluid analysis (CSF) showed high varicella-zoster virus (VZV)-DNA viral load (>300,000,000 copies/ml). VZV antibodies in CSF was ≥1:16. Diagnosis of neurological reactivati...

journal_title：Journal of neurovirology

authors： Del Borgo C,Belvisi V,Valli MB,Currà A,Pozzetto I,Sepe M,Mastroianni CM

更新日期：2017-08-01 00:00:00

abstract：:Nipah virus is a recently emergent paramyxovirus that is capable of causing severe disease in both humans and animals. The first outbreak of Nipah virus occurred in Malaysia and Singapore in 1999 and, more recently, outbreaks were detected in Bangladesh. In humans, Nipah virus causes febrile encephalitis with respirat...

journal_title：Journal of neurovirology

authors： Bellini WJ,Harcourt BH,Bowden N,Rota PA

更新日期：2005-10-01 00:00:00

abstract：:Viral oncolytic therapy for malignant brain tumors involves local intratumoral delivery of a genetically engineered virus with tumor cell-specific lytic activity. Promising preliminary results have been achieved in preclinical models with G207, a replication-competent herpes simplex virus type 1 constructed with multi...

journal_title：Journal of neurovirology

authors： Radbill AE,Reddy AT,Markert JM,Wyss JM,Pike MM,Akella NS,Bharara N,Gillespie GY

更新日期：2007-04-01 00:00:00

abstract：:We present an immunocompetent patient with transverse myelitis (TM) during acute cytomegalovirus (CMV) infection, as evidenced by a reactive serum CMV IgM and CMV viremia. The patient had an excellent outcome after receiving only high-dose methylprednisolone. Given concerns that practitioners may have around the use o...

journal_title：Journal of neurovirology

authors： Budhram A,Liu Y,Krawczyk M,Chan TLH,Burneo JG,Hosseini-Moghaddam SM,Shoesmith C

更新日期：2019-06-01 00:00:00

abstract：:Flavivirus encephalitis is believed to be the result of two main mechanisms: (i) direct damage to and dysfunction of neurons as a result of viral replication and (ii) destruction of the brain tissue by an inflammatory response. The differential impact of both mechanisms on the progression of flavivirus encephalitis ha...

journal_title：Journal of neurovirology

authors： Leyssen P,Paeshuyse J,Charlier N,Van Lommel A,Drosten C,De Clercq E,Neyts J

更新日期：2003-02-01 00:00:00

abstract：:This single-center study attempts to quantify the incidence of symptomatic CSF viral escape (CSFVE) in patients receiving atazanavir/r (ATV/r)-containing regimen. We performed a retrospective analysis of patients receiving ATV/r-containing ART who were diagnosed with symptomatic CSFVE from August 2012 to January 2017....

journal_title：Journal of neurovirology

authors： Patel AK,Patel KK,Gohel S,Kumar A,Letendre S

更新日期：2018-08-01 00:00:00

abstract：:In the era of the AIDS pandemic, progressive multifocal leukoencephalopathy (PML) has ceased being a rare disease. Prevalence estimates from clinical and pathological series suggest that up to 5% of all HIV-infected persons will develop PML. The extraordinary frequency with which PML attends HIV infection vastly excee...

journal_title：Journal of neurovirology

authors： Berger JR

更新日期：2003-01-01 00:00:00

abstract：:We report varicella-zoster virus (VZV) meningitis in a healthy adult woman with no antecedent rash and with hypoglycorrhachia. Cerebrospinal fluid (CSF) examination revealed the presence of VZV DNA, anti-VZV immunoglobulin G (IgG) antibody, and intrathecal production of anti-VZV IgG antibody. ...

journal_title：Journal of neurovirology

authors： Habib AA,Gilden D,Schmid DS,Safdieh JE

更新日期：2009-04-01 00:00:00

abstract：:There is controversy with regard to the entry pathway of the rabies virus (RABV) into the central nervous system (CNS). Some authors have suggested that the virus inoculated at the periphery is captured and transported to CNS only by motor neurons; however, it has been reported that dorsal root ganglia (DRG) sensory n...

journal_title：Journal of neurovirology

authors： Velandia-Romero ML,Castellanos JE,Martínez-Gutiérrez M

更新日期：2013-08-20 00:00:00

abstract：:The flaviviruses dengue, West Nile, and Japanese encephalitis represent three major mosquito-borne viruses worldwide. These pathogens impact the lives of millions of individuals and potentially could affect non-endemic areas already colonized by mosquito vectors. Unintentional transport of infected vectors (Aedes and ...

journal_title：Journal of neurovirology

authors： Daep CA,Muñoz-Jordán JL,Eugenin EA

更新日期：2014-12-01 00:00:00

abstract：:Activated murine cytotoxic T cells express the NKG2D natural cytotoxicity receptor. This receptor recognizes major histocompatibility complex (MHC) class I-like molecules expressed on the surface of infected cells and serves to augment T cell-mediated cytotoxicity. The role of NKG2D-mediated augmentation in the cleara...

journal_title：Journal of neurovirology

authors： Deb C,Howe CL

更新日期：2008-05-01 00:00:00

abstract：:To verify the possibility of different role of JC virus genotypes in the etiology of progressive multifocal leukoencephalopathy, we analysed several JC virus isolates amplified from AIDS patients with and without progressive multifocal leukoencephalopathy and healthy controls by nucleotide sequencing. Cerebrospinal fl...

journal_title：Journal of neurovirology

authors： Ferrante P,Mediati M,Caldarelli-Stefano R,Losciale L,Mancuso R,Cagni AE,Maserati R

更新日期：2001-02-01 00:00:00

abstract：:Both HIV disease and advanced age have been associated with alterations to cerebral white matter, as measured with white matter hyperintensities (WMH) on fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI), and more recently with diffusion tensor imaging (DTI). This study investigates the comb...

journal_title：Journal of neurovirology

authors： Seider TR,Gongvatana A,Woods AJ,Chen H,Porges EC,Cummings T,Correia S,Tashima K,Cohen RA

更新日期：2016-04-01 00:00:00

abstract：:The expression of cognitive symptoms associated with HIV varies over time and across individuals. This pattern may reflect transient contextual factors, including the degree of effort exerted by individuals undergoing cognitive testing. The present study examined whether effort corresponds to the expression of persist...

journal_title：Journal of neurovirology

authors： Paul R,Rhee G,Baker LM,Vaida F,Cooley SA,Ances BM

更新日期：2017-10-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease affecting the central nervous system as a result of reactivation of the John Cunningham (JC) polyomavirus and occurs almost exclusively in immunosuppressed individuals. The disease course of PML is variable but usually progressive and often fa...

journal_title：Journal of neurovirology

authors： Holmes A,Wellings T,Walsh O,Rowlings P

更新日期：2020-12-01 00:00:00