MRI of spinal cord in MS.

abstract：:Cytomegalovirus (CMV) infections are common and severe complications of HIV infection. The virus involves the nervous system, causing encephalitis, polyradiculomyelitis and peripheral neuropathies. Due to their limited sensitivity, traditional virological approaches, such as virus isolation or antigen detection in the...

journal_title：Journal of neurovirology

authors： Cinque P,Cleator GM,Weber T,Monteyne P,Sindic C,Gerna G,van Loon AM,Klapper PE

更新日期：1998-02-01 00:00:00

abstract：:The interplay between pathology and human immunodeficiency virus (HIV) expansion in brain tissues has not been thoroughly assessed in the highly active antiretroviral therapy (HAART) era. HIV-associated dementia (HAD) is marked by progressive brain infection due to recruitment and migration of macrophages in brain tis...

journal_title：Journal of neurovirology

authors： Lamers SL,Salemi M,Galligan DC,Morris A,Gray R,Fogel G,Zhao L,McGrath MS

更新日期：2010-05-01 00:00:00

abstract：:In order to examine the effect of HTLV-I proviral load on the pathogenesis of HAM/TSP, we measured the HTLV-I proviral load in peripheral blood mononuclear cells (PBMC) from a large number of HAM/TSP patients and asymptomatic HTLV-I carriers. To measure the proviral load, we used an accurate and reproducible quantitat...

journal_title：Journal of neurovirology

authors： Nagai M,Usuku K,Matsumoto W,Kodama D,Takenouchi N,Moritoyo T,Hashiguchi S,Ichinose M,Bangham CR,Izumo S,Osame M

更新日期：1998-12-01 00:00:00

abstract：:Maintaining the viral genome intact following infection and prior to replication is critical to the virus life cycle. Here we report an analysis of the stability of herpes simplex virus type 1 (HSV-1) genomes, relative to host chromosomal DNA, in infected cells as a function of viral induced apoptosis. The results sho...

journal_title：Journal of neurovirology

authors： Su YH,Zhang X,Aiamkitsumrit B,Tang Q,Maul G,Fraser NW,Block TM

更新日期：2006-10-01 00:00:00

abstract：:Most murine hepatitis virus (MHV) strains, as their name suggests, infect the liver. However, several murine strains are tropic for the central nervous system (CNS) and cause encephalitis with subsequent CNS demyelination. The CNS demyelination shares pathological similarities with human CNS demyelinating diseases suc...

journal_title：Journal of neurovirology

authors： Matthews AE,Weiss SR,Paterson Y

更新日期：2002-04-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease affecting the central nervous system as a result of reactivation of the John Cunningham (JC) polyomavirus and occurs almost exclusively in immunosuppressed individuals. The disease course of PML is variable but usually progressive and often fa...

journal_title：Journal of neurovirology

authors： Holmes A,Wellings T,Walsh O,Rowlings P

更新日期：2020-12-01 00:00:00

abstract：:In order to learn more about the cellular response to viral gene activity during latency and reactivation of herpes simplex virus type 1 (HSV-1), the authors have employed microarray analysis. On an array of about 1200 cellular genes, approximately 56 genes were found to be differentially regulated in infected trigemi...

journal_title：Journal of neurovirology

authors： Kent JR,Fraser NW

更新日期：2005-08-01 00:00:00

abstract：:The mechanisms underlying central nervous system (CNS) toxicities in antiretroviral-treated persons living with HIV (PLWH) remain elusive. We investigated the associations between markers of tryptophan metabolism and measurements of CNS toxicity in PLWH. In a prospective study, virologically suppressed PLWH receiving ...

journal_title：Journal of neurovirology

authors： Keegan MR,Winston A,Higgs C,Fuchs D,Boasso A,Nelson M

更新日期：2019-02-01 00:00:00

abstract：:Toscana virus (Bunyaviridae family, Phlebovirus genus) is a sandfly fever virus responsible for human neurological infections. Sandfly viruses are transmitted by insect vectors (Phlebotomus species) and the infection is present in climatic areas that allow the life cycle of the vector. The arthropode-borne Toscana vir...

journal_title：Journal of neurovirology

authors： Valassina M,Cusi MG,Valensin PE

更新日期：2003-12-01 00:00:00

abstract：:HIV-infected individuals with severe immune suppression are more likely to develop HIV-associated neurocognitive disorders than those with preserved immune function. While partial immune reconstitution occurs in those with severe immune suppression after starting combined antiretroviral therapy, it is not established ...

journal_title：Journal of neurovirology

authors： Zhu T,Zhong J,Hu R,Tivarus M,Ekholm S,Harezlak J,Ombao H,Navia B,Cohen R,Schifitto G

更新日期：2013-02-01 00:00:00

abstract：:Metabolic syndrome (MetS), a constellation of related metabolic risk factors, is a common comorbidity associated with cognitive difficulty in people living with HIV (PLWH). Neurobehavioral disturbances (e.g., behavioral manifestations of frontal-subcortical dysfunction) are also prevalent in HIV, yet the role MetS mig...

journal_title：Journal of neurovirology

authors： Pope CN,Montoya JL,Vasquez E,Pérez-Santiago J,Ellis R,McCutchan JA,Jeste DV,Moore DJ,Marquine MJ

更新日期：2020-12-01 00:00:00

abstract：:Maedi Visna Virus (MVV) is a prototypic lentivirus that causes infection only in cells of macrophage lineage, unlike the primate lentiviruses which infect both CD4+ T lymphocytes and macrophages. In primates, the earliest viral invasion is associated with the ability of the virus to infect and activate T cells which c...

journal_title：Journal of neurovirology

authors： Chebloune Y,Karr BM,Raghavan R,Singh DK,Leung K,Sheffer D,Pinson D,Foresman L,Narayan O

更新日期：1998-02-01 00:00:00

abstract：:It is increasingly evident that the human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) has a unique role in neuropathogenesis. Its ability to induce G2/M arrest coupled with its capacity to increase viral gene transcription gives it a unique role in sustaining viral replication and aiding in the establi...

journal_title：Journal of neurovirology

authors： James T,Nonnemacher MR,Wigdahl B,Krebs FC

更新日期：2016-08-01 00:00:00

abstract：:The brain's intrinsic immune system consists of glial cells that produce cytokines and chemokines in response to stimulation with cytomegalovirus (CMV). The present experiments were undertaken to determine whether this intrinsic glial cell response alone is sufficient to control CMV infection of the central nervous sy...

journal_title：Journal of neurovirology

authors： Cheeran MC,Gekker G,Hu S,Min X,Cox D,Lokensgard JR

更新日期：2004-06-01 00:00:00

abstract：:Epstein-Barr virus (EBV) associated central nervous system (CNS) infection is a rare disease. We report an atypical manifestation of EBV encephalitis initially presenting with a tumor-like lesion of the optic tract in an immunocompromised patient 8 years after a combined kidney and pancreas transplantation had been pe...

journal_title：Journal of neurovirology

authors： Khalil M,Enzinger C,Wallner-Blazek M,Scarpatetti M,Barth A,Horn S,Reiter G

更新日期：2008-11-01 00:00:00

abstract：:With the growing number of COVID-19 cases in recent times. significant set of patients with extra pulmonary symptoms has been reported worldwide. Here we venture out to summarize the clinical profile, investigations, and radiological findings among patients with SARS-CoV-2-associated meningoencephalitis in the form of...

journal_title：Journal of neurovirology

authors： Mondal R,Ganguly U,Deb S,Shome G,Pramanik S,Bandyopadhyay D,Lahiri D

更新日期：2020-12-26 00:00:00

abstract：:Excessive glutamate neurotransmission has been implicated in neuronal injury in many disorders of the central nervous system (CNS), including human immunodeficiency virus (HIV)-associated dementia. Gp120IIIB is a strain of a HIV glycoprotein with specificity for the CXCR4 receptor that induces neuronal apoptosis in in...

journal_title：Journal of neurovirology

authors： Thomas AG,Bodner A,Ghadge G,Roos RP,Slusher BS

更新日期：2009-09-01 00:00:00

abstract：:We aimed to test the hypothesis that brain large artery diameters relate to distal downstream arteriolar diameters. In a sample of 110 autopsied individuals (69% men, 76% HIV+, mean age 51), we used multilevel models to relate large artery lumen and lumen-to-wall ratio to left frontal lobe arteriolar lumen and lumen-t...

journal_title：Journal of neurovirology

authors： Gutierrez J,Murray J,Chon C,Morgello S

更新日期：2018-02-01 00:00:00

abstract：:The rabies virus glycoprotein (G) gene of the highly neuroinvasive and neurotropic strains SHBRV-18, CVS-N2c, and CVS-B2c was introduced into the non-neuroinvasive and less neurotropic SN-10 strain to provide further insight into the role of G in the pathogenesis of rabies. Phenotypic analyses of the recombinant virus...

journal_title：Journal of neurovirology

authors： Morimoto K,Foley HD,McGettigan JP,Schnell MJ,Dietzschold B

更新日期：2000-10-01 00:00:00

abstract：:Quinolinic acid (QUIN) is a tryptophan metabolite which has been found to be an excitotoxin in rats, although its toxicity in humans is unknown. QUIN has been implicated in the pathogenesis of AIDS dementia complex. This study examined the effect of QUIN on human fetal brain tissue in vitro. After at least 14 days in ...

journal_title：Journal of neurovirology

authors： Kerr SJ,Armati PJ,Brew BJ

更新日期：1995-12-01 00:00:00

abstract：:We present the case of a 43-year-old-man with a past medical history of HIV with recently initiated HAART and existing PML that presented with altered mental status. The initial diagnosis was deemed to be PML-IRIS; however, neuroimaging brought into question this diagnosis. Flow cytometry performed from the cerebrospi...

journal_title：Journal of neurovirology

authors： Reddi A,Patel N,Morris NA

更新日期：2019-12-01 00:00:00

abstract：:Amplification of viral nucleic acids from the cerebrospinal fluid (CSF) has considerably improved the diagnosis of several acute, subacute and chronic viral infections of the nervous system. In herpes simplex virus (HSV) encephalitis (HSE) the polymerase chain reaction (PCR) has become the method of choice for the rap...

journal_title：Journal of neurovirology

authors： Weber T,Frye S,Bodemer M,Otto M,Lüke W

更新日期：1996-06-01 00:00:00

abstract：:Although HIV-associated dementia (HAD) occurs in less than 5 % of individuals with access to combination antiretroviral therapy, rates of milder forms of HIV-associated neurocognitive disorder (HAND) are much higher. We sought to define an optimal cut point for the International HIV Dementia Scale (IHDS) in Thailand f...

journal_title：Journal of neurovirology

authors： Chalermchai T,Valcour V,Sithinamsuwan P,Pinyakorn S,Clifford D,Paul RH,Tipsuk S,Fletcher JL,Degruttola V,Ratto-Kim S,Hutchings N,Shikuma C,Ananworanich J,SEARCH 007 and 011 study groups.

更新日期：2013-04-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) dementia remains as an important cause of neurological morbidity among HIV-seropositive (HIV+) individuals. Differences in the neuropsychological profiles between older and younger HIV+ individuals have not been examined extensively. The objective of this study was to examine the neu...

journal_title：Journal of neurovirology

authors： Sacktor N,Skolasky R,Selnes OA,Watters M,Poff P,Shiramizu B,Shikuma C,Valcour V

更新日期：2007-06-01 00:00:00

abstract：:Both HIV disease and advanced age have been associated with alterations to cerebral white matter, as measured with white matter hyperintensities (WMH) on fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI), and more recently with diffusion tensor imaging (DTI). This study investigates the comb...

journal_title：Journal of neurovirology

authors： Seider TR,Gongvatana A,Woods AJ,Chen H,Porges EC,Cummings T,Correia S,Tashima K,Cohen RA

更新日期：2016-04-01 00:00:00

abstract：:Cytomegalovirus (CMV) infection is an important cause of neurologic disease in the context of advanced human immunodeficiency virus (HIV) infection and is recognized as a cause of immune reconstitution inflammatory syndrome (IRIS) after initiation of highly active antiretroviral therapy (HAART). Central nervous system...

journal_title：Journal of neurovirology

authors： Anderson AM,Fountain JA,Green SB,Bloom SA,Palmore MP

更新日期：2010-03-01 00:00:00

abstract：:It has recently been shown that bacteria and viruses can be delivered to the brain parenchyma without evoking an immune response. These experiments demonstrate that there are no cells within the brain parenchyma that can initiate a primary immune response, and that the drainage of pathogens from the brain parenchyma i...

journal_title：Journal of neurovirology

authors： Perry VH

更新日期：2000-05-01 00:00:00

abstract：:A method is described for amplification of the complete genome of the human polyomavirus JC (JCV) from progressive multifocal leukuencephalopathy (PML) brain, cerebrospinal fluid (CSF) of PML patients, and from the urine of controls without neurological disease. Efficient amplification with the 'long PCR' method is ac...

journal_title：Journal of neurovirology

authors： Agostini HT,Stoner GL

更新日期：1995-09-01 00:00:00

abstract：:Despite common clinical features to suggest encephalitis, different viral encephalitides are known to have some specific clinical features, which if present, may suggest infection by a particular virus. West Nile viral (WNV) encephalitis has not been described with any specific diagnostic feature so far. In this conte...

journal_title：Journal of neurovirology

authors： Pradhan S,Anand S,Choudhury SS

更新日期：2019-06-01 00:00:00

abstract：:To determine the possible influence of satellite glial cells on restricting the spread of herpes simplex virus in the peripheral nervous system, HSV replication was studied in clonally derived cultures of satellite glial cells from adult animals. Satellite cells were purified by exploiting their close anatomical assoc...

journal_title：Journal of neurovirology

authors： Wilkinson R,Leaver C,Simmons A,Pereira RA

更新日期：1999-08-01 00:00:00