Molecular and cellular mechanisms for microbial entry into the CNS.

abstract：:In HIV patients, HCV co-infection has been associated with an increased risk of progressive multifocal leukoencephalopathy (PML). Furthermore, PML has also been described in patients with cirrhosis, whether related to HCV infection or not. We describe here the case of a HIV/HCV co-infected patient with cirrhosis who d...

journal_title：Journal of neurovirology

authors： Hentzien M,Guihot A,de Maindreville D,Tabary T,Brodard V,Vieillard V,Adle-Biassette H,Bani-Sadr F

更新日期：2020-08-01 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) play important roles in regulating eukaryotic genome replication and gene expression in diverse biological systems. Here, we identified lncRNAs transcribed from pseudorabies virus (PRV)-infected PK-15 cells. Based on high-throughput sequencing data, we obtained 87,263,926 and 93,947,628 c...

journal_title：Journal of neurovirology

authors： Guan X,Liu J,Jiang H,Wu CX,Chen HC,Liu ZF

更新日期：2018-10-01 00:00:00

abstract：:Toscana virus (Bunyaviridae family, Phlebovirus genus) is a sandfly fever virus responsible for human neurological infections. Sandfly viruses are transmitted by insect vectors (Phlebotomus species) and the infection is present in climatic areas that allow the life cycle of the vector. The arthropode-borne Toscana vir...

journal_title：Journal of neurovirology

authors： Valassina M,Cusi MG,Valensin PE

更新日期：2003-12-01 00:00:00

abstract：:Most natural killer (NK) T cells express an invariant Valpha14 T-cell receptor. To explore the contribution of NKT cells in an animal model for multiple sclerosis, Theiler's murine encephalomyelitis virus (TMEV) infection, TMEV-infected mice were treated with Valpha14 antibody. Treatment during the early stage of infe...

journal_title：Journal of neurovirology

authors： Tsunoda I,Tanaka T,Taniguchi M,Fujinami RS

更新日期：2009-01-01 00:00:00

abstract：:Infection with human immunodeficiency virus-1 (HIV-1), the causative agent of acquired immunodeficiency syndrome (AIDS) in humans, causes a spectrum of neuropathology that includes alterations in behavior, changes in evoked potentials, and neuronal degeneration. In the simian immunodeficiency virus (SIV) model of HIV ...

journal_title：Journal of neurovirology

authors： Marcario JK,Manaye KF,SantaCruz KS,Mouton PR,Berman NE,Cheney PD

更新日期：2004-12-01 00:00:00

abstract：:Two human alpha-herpesviruses, herpes simplex virus (HSV)-1 and varicella zoster virus (VZV), account for the most frequent and serious neurologic disease caused by any of the eight human herpesviruses. Both HSV-1 and VZV become latent in ganglia. In this review, the authors describe features of latency for these viru...

journal_title：Journal of neurovirology

authors： Mitchell BM,Bloom DC,Cohrs RJ,Gilden DH,Kennedy PG

更新日期：2003-04-01 00:00:00

abstract：:Zimbabwe is a high prevalence area for HIV infection, and provides opportunities for studying complications of AIDS in both antiretroviral naive and treated groups of patients. Figures for HIV prevalence are among the highest in the world, but the number of people receiving treatment is very small. Economic and politi...

journal_title：Journal of neurovirology

authors： Mielke J

更新日期：2005-01-01 00:00:00

abstract：:Older HIV-infected men are at higher risk for both depression and cognitive impairments, compared to HIV-uninfected men. We evaluated the association between longitudinal patterns of depressive symptoms and attention/executive function in HIV-infected and HIV-uninfected men aged 50+ years to understand whether HIV inf...

journal_title：Journal of neurovirology

authors： Armstrong NM,Surkan PJ,Treisman GJ,Sacktor NC,Irwin MR,Teplin LA,Stall R,Martin EM,Becker JT,Munro C,Levine AJ,Jacobson LP,Abraham AG

更新日期：2017-08-01 00:00:00

abstract：:A recombinant adenovirus vector bearing the IL-4 gene (AD-IL-4) was used to infect rat glioma C6 cells in culture at multiplicity of infections (MOI) from 50 to 1800. C6 cell proliferation was not altered significantly by adenoviral infection. However, IL-4 production increased in a dose-dependent manner. To ascertain...

journal_title：Journal of neurovirology

authors： Wei MX,Li F,Ono Y,Gauldie J,Chiocca EA

更新日期：1998-04-01 00:00:00

abstract：:The flaviviruses dengue, West Nile, and Japanese encephalitis represent three major mosquito-borne viruses worldwide. These pathogens impact the lives of millions of individuals and potentially could affect non-endemic areas already colonized by mosquito vectors. Unintentional transport of infected vectors (Aedes and ...

journal_title：Journal of neurovirology

authors： Daep CA,Muñoz-Jordán JL,Eugenin EA

更新日期：2014-12-01 00:00:00

abstract：:A pandemic due to novel coronavirus arose in mid-December 2019 in Wuhan, China, and in 3 months' time swept the world. The disease has been referred to as COVID-19, and the causative agent has been labelled SARS-CoV-2 due to its genetic similarities to the virus (SARS-CoV-1) responsible for the severe acute respirator...

journal_title：Journal of neurovirology

authors： Berger JR

更新日期：2020-04-01 00:00:00

abstract：:The neuromotor rehabilitative treatment should be joined in the global individualised project. The rehabilitation project is developed by an interdisciplinary. Hence, the clinicians have to promote an appropriate compensation process in the daily living activities with a rapid insertion of new or recovered motor-postu...

journal_title：Journal of neurovirology

authors： Cardini RG,Crippa AC,Cattaneo D

更新日期：2000-05-01 00:00:00

abstract：:In order to examine the effect of HTLV-I proviral load on the pathogenesis of HAM/TSP, we measured the HTLV-I proviral load in peripheral blood mononuclear cells (PBMC) from a large number of HAM/TSP patients and asymptomatic HTLV-I carriers. To measure the proviral load, we used an accurate and reproducible quantitat...

journal_title：Journal of neurovirology

authors： Nagai M,Usuku K,Matsumoto W,Kodama D,Takenouchi N,Moritoyo T,Hashiguchi S,Ichinose M,Bangham CR,Izumo S,Osame M

更新日期：1998-12-01 00:00:00

abstract：:In 2007, the nosology for HIV-1-associated neurocognitive disorders (HAND) was updated to a primarily neurocognitive disorder. However, currently available diagnostic tools lack the sensitivity and specificity needed for an accurate diagnosis for HAND. Scientists and clinicians, therefore, have been on a quest for an ...

journal_title：Journal of neurovirology

authors： McLaurin KA,Booze RM,Mactutus CF

更新日期：2019-10-01 00:00:00

abstract：:Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is chronic myelopathy characterized by slowly progressive spastic paraparesis and urinary dysfunction. A few biomarkers in the cerebrospinal fluid are known to be related to disease activity, but no biomarker has be...

journal_title：Journal of neurovirology

authors： Takenouchi N,Tanaka M,Sato T,Yao J,Fujisawa JI,Izumo S,Kubota R,Matsuura E

更新日期：2020-06-01 00:00:00

abstract：:We present an immunocompetent patient with transverse myelitis (TM) during acute cytomegalovirus (CMV) infection, as evidenced by a reactive serum CMV IgM and CMV viremia. The patient had an excellent outcome after receiving only high-dose methylprednisolone. Given concerns that practitioners may have around the use o...

journal_title：Journal of neurovirology

authors： Budhram A,Liu Y,Krawczyk M,Chan TLH,Burneo JG,Hosseini-Moghaddam SM,Shoesmith C

更新日期：2019-06-01 00:00:00

abstract：:The Chikungunya virus (CHIKV) is an arbovirus transmitted to humans through mosquito bites and can cause a series of symptoms ranging from a benign febrile illness to severe neurological conditions. We report the identification of CHIKV in a serum sample from an elderly woman with febrile illness and severe arthralgia...

journal_title：Journal of neurovirology

authors： Silva VP,Costa DS,Carvalho VCCVL,Garcês TCCS,Barros ELT,Oliveira JS,Pereira ACTC,Ferreira GP

更新日期：2020-02-01 00:00:00

abstract：:In order to learn more about the cellular response to viral gene activity during latency and reactivation of herpes simplex virus type 1 (HSV-1), the authors have employed microarray analysis. On an array of about 1200 cellular genes, approximately 56 genes were found to be differentially regulated in infected trigemi...

journal_title：Journal of neurovirology

authors： Kent JR,Fraser NW

更新日期：2005-08-01 00:00:00

abstract：:Pseudorabies virus (PRV) primarily infects swine but can infect cattle, dogs, and cats. Several studies have reported that PRV can cross the specie barrier and induce human encephalitis, but a definitive diagnosis of human PRV encephalitis is debatable due to the lack of PRV DNA detection. Here, we report a case of hu...

journal_title：Journal of neurovirology

authors： Wang D,Tao X,Fei M,Chen J,Guo W,Li P,Wang J

更新日期：2020-06-01 00:00:00

abstract：:Previous animal studies have identified a C31S residue substitution in the C30C31 dicysteine motif of the Tat protein that is associated with reduced neurovirulence in clade C human immunodeficiency virus (HIV). However, clinical studies of patients infected with clade C HIV have reported significant levels of cogniti...

journal_title：Journal of neurovirology

authors： Paul RH,Joska JA,Woods C,Seedat S,Engelbrecht S,Hoare J,Heaps J,Valcour V,Ances B,Baker LM,Salminen LE,Stein DJ

更新日期：2014-12-01 00:00:00

abstract：:Highly active antiretroviral treatment has led to unprecedented efficacy and tolerability in people living with HIV. This effect was also observed in the central nervous system with the nowadays uncommon observation of dementias; yet in more recent works milder forms are still reported in 20-30% of optimally treated i...

journal_title：Journal of neurovirology

authors： De Benedetto I,Trunfio M,Guastamacchia G,Bonora S,Calcagno A

更新日期：2020-10-01 00:00:00

abstract：:The aim of this study was to review the quality of the diagnostic work-up for acute encephalitis carried out at our center in a cohort of patients with hematological disorders. Our data showed substantial heterogeneity in investigating patients. Not all patients had their CSF tested for viruses commonly responsible fo...

journal_title：Journal of neurovirology

authors： Vegezzi E,Berzero G,Barbetta D,Colombo AA,Borsani O,Bernasconi P,Compagno F,Zecca M,Campanini G,Simoncelli A,Paoletti M,Pichiecchio A,Baldanti F,Brunetti E,Marchioni E

更新日期：2020-04-01 00:00:00

abstract：:The rabies virus glycoprotein (G) gene of the highly neuroinvasive and neurotropic strains SHBRV-18, CVS-N2c, and CVS-B2c was introduced into the non-neuroinvasive and less neurotropic SN-10 strain to provide further insight into the role of G in the pathogenesis of rabies. Phenotypic analyses of the recombinant virus...

journal_title：Journal of neurovirology

authors： Morimoto K,Foley HD,McGettigan JP,Schnell MJ,Dietzschold B

更新日期：2000-10-01 00:00:00

abstract：:We generated several lines of mice transgenic for the lacZ reporter gene under the control of an HTLV-I LTR. Two different LTR were used; one was isolated from a case of Adult T-cell Leukemia (ATL), the other from a case of Tropical Spastic Paraparesis (TSP/HAM). These LTR differed at 18 nucleotide positions. The patt...

journal_title：Journal of neurovirology

authors： Coscoy L,Gonzalez-Dunia D,Chirinian-Swan S,Brahic M,Ozden S

更新日期：1996-10-01 00:00:00

abstract：:Age-dependent poliomyelitis (ADPM) is a virally induced neuroparalytic disease of mice and a model for amyotrophic lateral sclerosis (ALS). ADPM is triggered in genetically susceptible mice by immunosuppression and infection with lactate dehydrogenase-elevating virus (LDV). Both ADPM and ALS are characterized by progr...

journal_title：Journal of neurovirology

authors： Schlenker EH,Jones QA,Rowland RR,Steffen-Bien M,Cafruny WA

更新日期：2001-06-01 00:00:00

abstract：:Activated murine cytotoxic T cells express the NKG2D natural cytotoxicity receptor. This receptor recognizes major histocompatibility complex (MHC) class I-like molecules expressed on the surface of infected cells and serves to augment T cell-mediated cytotoxicity. The role of NKG2D-mediated augmentation in the cleara...

journal_title：Journal of neurovirology

authors： Deb C,Howe CL

更新日期：2008-05-01 00:00:00

abstract：:Enteroviruses (EV) are responsible for a large number of meningoencephalitis cases, especially in children. The objective of this study was to identify modes of diagnosis including the significance of respiratory and cerebrospinal fluid samples, associated clinical characteristics, inpatient management, and outcome of...

journal_title：Journal of neurovirology

authors： Torres SD,Jia DT,Schorr EM,Park BL,Boubour A,Boehme A,Ankam JV,Gofshteyn JS,Tyshkov C,Green DA,Vargas W,Zucker J,Yeshokumar AK,Thakur KT

更新日期：2020-02-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) and viral proteins affect neuronal survival and neuron-glial cell interactions, which culminate in neurological disorders. HIV-1 infects regions of neurogenesis in human adult and pediatric brain. However, little is known about the effect of HIV-1 or viral proteins on the pr...

journal_title：Journal of neurovirology

authors： Mishra M,Taneja M,Malik S,Khalique H,Seth P

更新日期：2010-10-01 00:00:00

abstract：:Herpes simplex encephalitis relapses have been rarely reported, with only few cases occurring after neurosurgical interventions. A young man presented a late herpes simplex encephalitis relapse after left antero-mesial temporal resection for his refractory temporal lobe epilepsy. Eight days after surgery, he developed...

journal_title：Journal of neurovirology

authors： Mantero V,Cossu M,Rigamonti A,Fiumani A,Basilico P,Tassi L,Salmaggi A

更新日期：2020-02-01 00:00:00

abstract：:Metabolic syndrome (MetS), a constellation of related metabolic risk factors, is a common comorbidity associated with cognitive difficulty in people living with HIV (PLWH). Neurobehavioral disturbances (e.g., behavioral manifestations of frontal-subcortical dysfunction) are also prevalent in HIV, yet the role MetS mig...

journal_title：Journal of neurovirology

authors： Pope CN,Montoya JL,Vasquez E,Pérez-Santiago J,Ellis R,McCutchan JA,Jeste DV,Moore DJ,Marquine MJ

更新日期：2020-12-01 00:00:00