Strategies to prevent and control hepatitis B and C virus infections: a global perspective.

abstract：:The growth of Mycobacterium w, a candidate strain for leprosy vaccine in submerged culture, was inhibited by the presence of over 40% oxygen saturation in the medium. Intracellular levels of superoxide dismutase and catalase were very low in the beginning. However, under controlled oxygenation, these levels increased ...

journal_title：Vaccine

authors： Mukhopadhyay A,Panda AK,Pandey AK

更新日期：1998-08-01 00:00:00

abstract：:Dengue is a significant threat to public health worldwide. Currently, there are no licensed vaccines available for dengue. Takeda Vaccines Inc. is developing a live, attenuated tetravalent dengue vaccine candidate (TDV) that consists of an attenuated DENV-2 strain (TDV-2) and three chimeric viruses containing the prM ...

journal_title：Vaccine

authors： Osorio JE,Partidos CD,Wallace D,Stinchcomb DT

更新日期：2015-12-10 00:00:00

abstract：:Previous work by our laboratory identified a fraction of Schistosoma mansoni soluble adult worm antigenic preparation, designated PIII, able to elicit significant in vitro cell proliferation, and lower in vitro and in vivo granuloma formation. In the present work, we investigated some biological activities of P24, an ...

journal_title：Vaccine

authors： Zouain CS,Gustavson S,Oliveira SC,Azevedo V,Alves JB,Goes AM

更新日期：2000-12-08 00:00:00

abstract：INTRODUCTION:Pregnancy is a risk factor for severe influenza. However, data on influenza incidence during pregnancy are scarce. Likewise, no data are available on influenza vaccine coverage in France since national recommendation in 2012. We aimed to assess these points using a novel nationwide web-based surveillance s...

journal_title：Vaccine

authors： Loubet P,Guerrisi C,Turbelin C,Blondel B,Launay O,Bardou M,Goffinet F,Colizza V,Hanslik T,Kernéis S,GGNET study group.

更新日期：2016-04-29 00:00:00

abstract：INTRODUCTION:New adjuvants such as the AS- or the MF59-adjuvants improve vaccine efficacy and facilitate dose-sparing. Their use in influenza and malaria vaccines has resulted in a large body of evidence on their clinical safety in children. METHODS:We carried out a systematic search for safety data from published cli...

journal_title：Vaccine

authors： Stassijns J,Bollaerts K,Baay M,Verstraeten T

更新日期：2016-02-03 00:00:00

abstract：:A gene encoding the mature Escherichia coli heat-labile enterotoxin B subunit (LTB) was introduced in a vector pNU212 and expressed at high levels in Bacillus brevis HPD31. The maximum amount of recombinant LTB (rLTB) secreted into the modified 5PY medium containing erythromycin was about 350 mg l(-1) when cultivated ...

journal_title：Vaccine

authors： Kozuka S,Yasuda Y,Isaka M,Masaki N,Taniguchi T,Matano K,Moriyama A,Ohkuma K,Goto N,Udaka S,Tochikubo K

更新日期：2000-03-06 00:00:00

abstract：:Dengue is one of the most important arboviral diseases in humans, and although efforts over the last decades have dealt with the development of a vaccine, this vaccine is not available yet. In order to evaluate the potential of a DNA vaccine based on the non-structural 1 (NS1) protein against dengue virus (DENV), we c...

journal_title：Vaccine

authors： Costa SM,Paes MV,Barreto DF,Pinhão AT,Barth OM,Queiroz JL,Armôa GR,Freire MS,Alves AM

更新日期：2006-01-12 00:00:00

abstract：:Induction of immune response as characterised by expression of cytokine genes in the spleen following immunization of pre- and post-hatch chickens with herpesvirus of turkeys (HVT) vaccine was studied. The pattern of expression of IFN-gamma and IL-10 genes in pre-hatch immunized chickens was different from that observ...

journal_title：Vaccine

authors： Abdul-Careem MF,Hunter DB,Lambourne MD,Read LR,Parvizi P,Sharif S

更新日期：2008-05-02 00:00:00

abstract：BACKGROUND:The objective of this study was to estimate the number of years after onset of a quadrivalent HPV vaccination program before notable reductions in genital warts and cervical intraepithelial neoplasia (CIN) will occur in teenagers and young adults in the United States. METHODS:We applied a previously publish...

journal_title：Vaccine

authors： Chesson HW,Ekwueme DU,Saraiya M,Dunne EF,Markowitz LE

更新日期：2013-08-20 00:00:00

abstract：:Inactivated porcine parvovirus (PPV) vaccines are available commercially and widely used in the breeding herds. However, inactivated PPV vaccines have deficiencies in induction of specific cellular immune response. Transfer factor (TF) is a material that obtained from the leukocytes, and is a novel immune-stimulatory ...

journal_title：Vaccine

authors： Wang RN,Wang YB,Geng JW,Guo DH,Liu F,Chen HY,Zhang HY,Cui BA,Wei ZY

更新日期：2012-07-27 00:00:00

abstract：:As part of a larger study exploring how European citizens' balance issues of public and private interest and the extent to which they are prepared to accept State intervention on a range of public health issues, focus group participants were asked whether childhood immunisation should be a matter of parental choice or...

journal_title：Vaccine

authors： Moran N,Shickle D,Richardson E

更新日期：2008-01-17 00:00:00

abstract：:In this review we aim to provide the reader with an understanding of the capsular-based complexity of Streptococcus pneumoniae, one of the main limitations to current vaccine development. We then discuss the need for a new vaccine strategy based on proteic antigen candidates discovered in silico. Describing specifical...

journal_title：Vaccine

authors： Barocchi MA,Censini S,Rappuoli R

更新日期：2007-04-20 00:00:00

abstract：:A recombinant vector vaccine uses an attenuated virus, bacterium, or parasite as the carrier to express a heterologous antigen(s). Many recombinant vaccine vectors and related vaccines have been developed and extensively investigated. To compare and better understand recombinant vectors and vaccines, we have generated...

journal_title：Vaccine

authors： Deng S,Martin C,Patil R,Zhu F,Zhao B,Xiang Z,He Y

更新日期：2015-11-27 00:00:00

abstract：:Human metapneumovirus (HMPV) is an important cause of acute respiratory tract disease for which the development of vaccine candidates is warranted. We have previously described the generation of an iscom matrix-adjuvanted HMPV fusion protein subunit vaccine (Fsol) and a live-attenuated vaccine (HMPVM11). Here, we eval...

journal_title：Vaccine

authors： Herfst S,Schrauwen EJ,de Graaf M,van Amerongen G,van den Hoogen BG,de Swart RL,Osterhaus AD,Fouchier RA

更新日期：2008-08-05 00:00:00

abstract：:Since vaccination against human papillomavirus (HPV) became available, awareness of HPV has dramatically increased. Implementation of a vaccine program varies internationally yet no studies have explored the influence this has on the public's knowledge of HPV. The present study aimed to explore differences in awarenes...

journal_title：Vaccine

authors： Marlow LA,Zimet GD,McCaffery KJ,Ostini R,Waller J

更新日期：2013-01-21 00:00:00

abstract：:Peptidoglycan monomer (PGM) originating from Brevibacterium divaricatum is a non-toxic, non-pyrogenic, water-soluble immunostimulator. It potentiates humoral immune response to ovalbumin (OVA) in mice upregulating both immunoglobulin (IgG) 1 and IgG2a antibody subclasses. This study concerns the influence of PGM on T ...

journal_title：Vaccine

authors： Halassy Spoljar B,Cimbora T,Hanzl-Dujmović I,Dojnović B,Sabioncello A,Krstanović M,Tomasić J

更新日期：2002-10-04 00:00:00

abstract：:The long-term impact of Haemophilus influenzae type b (Hib) conjugate vaccine, introduced throughout Latin America in the late 1990s, has not been evaluated. Active surveillance for H. influenzae meningitis was performed from August 9, 1996 to August 8, 2004 in Metropolitan Salvador, Brazil. Five years after the intro...

journal_title：Vaccine

authors： Ribeiro GS,Lima JB,Reis JN,Gouveia EL,Cordeiro SM,Lobo TS,Pinheiro RM,Ribeiro CT,Neves AB,Salgado K,Silva HR,Reis MG,Ko AI

更新日期：2007-05-30 00:00:00

abstract：BACKGROUND:Currently, one lifetime booster of a 23-valent pneumococcal polysaccharide vaccine (PPV23) is recommended for those at highest risk of invasive pneumococcal disease (IPD) 3-5 years after initial vaccination. Due to a lack of evidence on multiple revaccinations, recommendations on repeat revaccination do not ...

journal_title：Vaccine

authors： Caya CA,Boikos C,Desai S,Quach C

更新日期：2015-03-10 00:00:00

abstract：:This study investigated the immune response and safety in 430 adults, when boosted more than 3 years after primary or booster TBE immunisation as measured by neutralization test (NT) and ELISA. Tested by NT, the post-booster day 21 geometric mean titer (GMT) was 331 and 142 for the 18-49 and > or =50 years old, respec...

journal_title：Vaccine

authors： Rendi-Wagner P,Kundi M,Zent O,Banzhoff A,Jaehnig P,Stemberger R,Dvorak G,Grumbeck E,Laaber B,Kollaritsch H

更新日期：2004-12-09 00:00:00

abstract：:A short-term toxicity study was performed to investigate local reactions and haematological changes after intramuscular (i.m.) injection of meningococcal vaccine with a concentration of 25 or 50 micrograms protein ml-1. In these meningococcal vaccines up to 75 micrograms Zwittergent ml-1 was used to form a protein-det...

journal_title：Vaccine

authors： Speijers GJ,Danse LH,Beuvery EC,Derks HJ,Vos JG

更新日期：1988-10-01 00:00:00

abstract：:Groups of calves (20 per group) were vaccinated subcutaneously with a single dose of BCG Pasteur (6 x 10(4) or 6 x 10(6) colony forming units) and two months later, 15 calves from each group were challenged intratracheally with virulent Mycobacterium bovis. Vaccination with either dose of BCG induced significant prote...

journal_title：Vaccine

authors： Buddle BM,de Lisle GW,Pfeffer A,Aldwell FE

更新日期：1995-08-01 00:00:00

abstract：:In this study we quantified the transmission of pseudorabies virus (PRV) in well-immunized sow herds in The Netherlands. In three herds, sows were tested for antibodies to gE of PRV every time after they had been transported to another barn (survey A). In 99 other herds, sows were tested simultaneously once or twice y...

journal_title：Vaccine

authors： Van Nes A,Stegeman JA,De Jong MC,Loeffen WL,Kimman TG,Verheijden JH

更新日期：1996-08-01 00:00:00

abstract：:Synthetic oligodeoxynucleotides containing CpG immunostimulatory sequences (ISS) have been shown to act as potent adjuvants of type 1 immune responses when co-administered with protein or peptide vaccines. We have recently shown that ISS can increase the anti-polysaccharide (CHO) and anti-tetanus toxoid (TT) or anti-d...

journal_title：Vaccine

authors： von Hunolstein C,Mariotti S,Teloni R,Alfarone G,Romagnoli G,Orefici G,Nisini R

更新日期：2001-04-30 00:00:00

abstract：BACKGROUND:PCV13 (conjugated polysaccharide) and PPSV23 (polysaccharide only) are two licensed vaccines targeting S. pneumoniae. The role of CD4 T-cell responses in pneumococcal vaccines among healthy participants and their impact on antibodies is not yet known. METHODS:Ten adults (5 old and 5 young) received PCV13 (p...

journal_title：Vaccine

authors： Sterrett S,Peng BJ,Burton RL,LaFon DC,Westfall AO,Singh S,Pride M,Anderson AS,Ippolito GC,Schroeder HW Jr,Nahm MH,Krishna Prasad A,Goepfert P,Bansal A

更新日期：2020-02-11 00:00:00

abstract：BACKGROUND:MenB-4C (Bexsero®) is a multicomponent serogroup B meningococcal vaccine. For vaccine licensure, efficacy was inferred from serum bactericidal antibody (SBA) against three antigen-specific indicator strains. The bactericidal role of antibody to the fourth vaccine antigen, Neisserial Heparin binding antigen (...

journal_title：Vaccine

authors： Partridge E,Lujan E,Giuntini S,Vu DM,Granoff DM

更新日期：2017-07-24 00:00:00

abstract：:Cervical cancer that is associated with high-risk human papillomaviruses (HPV) is the most common malignancy in Indian women. Therefore, the establishment of a prevention program is urgently required considering both vaccination and screening. However, relatively little is known about the prevalence of the different H...

journal_title：Vaccine

authors： Gheit T,Vaccarella S,Schmitt M,Pawlita M,Franceschi S,Sankaranarayanan R,Sylla BS,Tommasino M,Gangane N

更新日期：2009-01-29 00:00:00

abstract：:We have demonstrated that vaccination of turkeys with an unformulated DNA vaccine induces significant protection against Chlamydophila (Cp.) psittaci infections. Nevertheless, the immunogenicity of the DNA vaccine can still be improved by increasing translation and transfection efficiency. Therefore, the ompA codon wa...

journal_title：Vaccine

authors： Verminnen K,Beeckman DS,Sanders NN,De Smedt S,Vanrompay DC

更新日期：2010-04-19 00:00:00

abstract：:With tuberculosis continuing to be a major cause of global morbidity and mortality, a new vaccine is urgently needed. Tuberculosis subunit vaccines have been shown to induce robust immune responses in humans and are a potentially safer alternative to BCG for use in HIV-endemic areas. In this study, we investigated the...

journal_title：Vaccine

authors： Derrick SC,Yabe IM,Yang A,Kolibab K,Hollingsworth B,Kurtz SL,Morris S

更新日期：2013-09-23 00:00:00

abstract：:In this article, we review three mechanisms that contribute to sustaining serum antibody levels: (i) long-lived plasma cells; (ii) persisting or cross-reactive antigen, and (iii) polyclonal activation of all memory B cells. We also present a quantitative analysis of the secondary immune response that reveals the relat...

journal_title：Vaccine

authors： Traggiai E,Puzone R,Lanzavecchia A

更新日期：2003-06-01 00:00:00

abstract：:Hepatitis B (HB) immunization was introduced as part of the expanded programme on immunization (EPI) in two provinces in Thailand and evaluated over a four year period. Three doses of HB vaccine were offered to 60,980 newborns at birth, 2 and 6 months of age. The overall coverage for complete HB immunization was 90.4%...

journal_title：Vaccine

authors： Chunsuttiwat S,Biggs BA,Maynard J,Thamapalo S,Laoboripat S,Bovornsin S,Charanasri U,Pinyowiwat W,Kunasol P

更新日期：1997-04-01 00:00:00