Immunological responses and protection against Mycobacterium bovis in calves vaccinated with a low dose of BCG.

abstract：BACKGROUND:The Global Vaccine Action Plan highlights the need for immunisation programmes to have sustainable access to predictable funding. A good understanding of current and future funding needs, commitments, and gaps is required to enhance planning, improve resource allocation and mobilisation, and to avoid funding...

journal_title：Vaccine

authors： Guthrie T,Zikusooka C,Kwesiga B,Abewe C,Lagony S,Schutte C,Marinda E,Humphreys K,Motlogelwa K,Nombewu ZC,Brenzel L,Kinghorn A

更新日期：2015-05-07 00:00:00

abstract：:Intranasal (i.n.) vaccination with two suboptimal doses of 8 microg of deglycosylated chain A ricin (DGCA) stimulated low anti-ricin ELISA IgG and neutralizing antibody responses and the vaccine was only marginally protective against a lethal ricin toxin aerosol challenge. However, in the presence of 4, 2, or 1 microg...

journal_title：Vaccine

authors： Kende M,Del Giudice G,Rivera N,Hewetson J

更新日期：2006-03-15 00:00:00

abstract：:The goal of the present study was to evaluate the influence of the influenza A H1N1/2009 vaccine on dermatomyositis/polymyositis (DM/PM) disease parameters and the potential deleterious effect of therapy on immune response. Thirty-seven DM and 21 PM patients (Bohan and Peter's criteria) were gender- and age-matched to...

journal_title：Vaccine

authors： Shinjo SK,de Moraes JC,Levy-Neto M,Aikawa NE,de Medeiros Ribeiro AC,Schahin Saad CG,Precioso A,Silva CA,Bonfá E

更新日期：2012-12-17 00:00:00

abstract：:Vibrio cholerae O139 Bengal strain was the causative agent of the recent epidemics of cholera in India and Bangladesh. We studied antibacterial and antitoxin immune responses in acute and convalescent phase paired sera collected from seven of these cholera patients. Significant rise in the levels of both antibacterial...

journal_title：Vaccine

authors： Nandy RK,Albert MJ,Ghose AC

更新日期：1996-08-01 00:00:00

abstract：:There is a need for more efficient vaccines to combat viral diseases of Atlantic salmon and other farmed fish. DNA vaccines are highly effective against salmonid rhabdoviruses, but have shown less effect against other viruses. In the present work we have studied if type I IFNs might be used as adjuvants in fish DNA va...

journal_title：Vaccine

authors： Chang CJ,Sun B,Robertsen B

更新日期：2015-05-15 00:00:00

abstract：:Since 2004, general varicella vaccination has been recommended for all children 11-14 months of age in Germany. The objective of this study was to examine vaccination coverage in children and factors associated with parental acceptance during the first years after recommendation. In a regional surveillance area, cross...

journal_title：Vaccine

authors： Streng A,Seeger K,Grote V,Liese JG

更新日期：2010-08-09 00:00:00

abstract：INTRODUCTION:Pregnancy is a risk factor for severe influenza. However, data on influenza incidence during pregnancy are scarce. Likewise, no data are available on influenza vaccine coverage in France since national recommendation in 2012. We aimed to assess these points using a novel nationwide web-based surveillance s...

journal_title：Vaccine

authors： Loubet P,Guerrisi C,Turbelin C,Blondel B,Launay O,Bardou M,Goffinet F,Colizza V,Hanslik T,Kernéis S,GGNET study group.

更新日期：2016-04-29 00:00:00

abstract：:To identify Mycobacterium tuberculosis (Mtb) antigens as candidates for a subunit vaccine against tuberculosis (TB), we have employed a CD4+ T-cell expression screening method. Mtb-specific CD4+ T-cell lines from nine healthy PPD positive donors were stimulated with different antigenic substrates including autologous ...

journal_title：Vaccine

authors： Coler RN,Dillon DC,Skeiky YA,Kahn M,Orme IM,Lobet Y,Reed SG,Alderson MR

更新日期：2009-01-07 00:00:00

abstract：:Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) is contracted via aerosol infection, typically affecting the lungs. Mycobacterium bovis bacillus Calmette-Guerin (BCG) is the only licensed vaccine and has variable efficacy in protecting against pulmonary TB. Additionally, chemotherapy is associated with l...

journal_title：Vaccine

authors： Ahmed M,Smith DM,Hamouda T,Rangel-Moreno J,Fattom A,Khader SA

更新日期：2017-09-05 00:00:00

abstract：:This study expands and updates through 1995 our earlier report on influenza vaccine use in 18 developed countries. Five of the six countries with high levels of vaccine use in 1992 (> or = 130 doses/1000 population) showed little change or slight declines over the subsequent 3 years. The exception was the United State...

journal_title：Vaccine

authors： Fedson DS,Hirota Y,Shin HK,Cambillard PE,Kiely J,Ambrosch F,Hannoun C,Leese J,Sprenger MJ,Hampson AW,Bro-Jørgensen K,Ahlbom AM,Nøkleby H,Valle M,Olafsson O,Salmerón F,Cloetta J,Rebelo de Andrade H,Snacken R,Donatell

更新日期：1997-10-01 00:00:00

abstract：:The bioavailability of oseltamivir phosphate and oseltamivir carboxylate were assessed in healthy volunteers when delivered as a solution of the active pharmaceutical ingredient (API) compared with the commercial capsule formulation. The 90% confidence intervals (CIs) for the ratios of the two treatments (capsule vers...

journal_title：Vaccine

authors： Brewster M,Smith JR,Dutkowski R,Robson R

更新日期：2006-11-10 00:00:00

abstract：:Vaccination with viral-based vaccines continues to hold promise for the prevention of malaria. Whilst antigen-specific T cell responses are considered a major aim of such an approach, a role for induced NK cells as anti-malarial effector cells, or in shaping T cell responses, has received less attention. In this study...

journal_title：Vaccine

authors： Berthoud TK,Fletcher H,Porter D,Thompson F,Hill AV,Todryk SM

更新日期：2009-12-10 00:00:00

abstract：:In HIV vaccine trials, the collection and analysis of participant behavior data associated with risk of acquiring HIV-infection is important for a number of reasons. Although the rationale for behavioral risk assessment in HIV vaccine clinical trials is clear, consistent collection of behavioral data over time and acr...

journal_title：Vaccine

authors： Andrasik MP,Karuna ST,Nebergall M,Koblin BA,Kublin JG,NIAID HIV Vaccine Trials Network.

更新日期：2013-09-13 00:00:00

abstract：:In many industrialized countries, hepatitis A incidence rates have declined steadily in the past decades. Since future cohorts of non-vaccinated elderly will lack protection against disease and the burden of hepatitis A is higher with increasing age, this could be an argument in favour of taking preventive measures su...

journal_title：Vaccine

authors： Suijkerbuijk AW,Lugnér AK,van Pelt W,Wallinga J,Verhoef LP,de Melker HE,de Wit GA

更新日期：2012-07-27 00:00:00

abstract：:In a severe pandemic, rapid production and deployment of vaccines will potentially be critical in mitigating the impact on populations and essential services. We compared access to vaccines and timing of delivery relative to identification of A(H1N1)pdm09 and the geographic progression of the pandemic in the WHO Europ...

journal_title：Vaccine

authors： Jorgensen P,Wasley A,Mereckiene J,Cotter S,Weber JT,Brown CS

更新日期：2013-08-28 00:00:00

abstract：:Sporozoite vaccination of both humans and rodents elicits potent anti-malarial immunity, but the dose of sporozoites and the number of immunizations required varies with vaccination approach. Here we examine the immunological basis for superior protection afforded from single-dose vaccination with virulent sporozoites...

journal_title：Vaccine

authors： Doll KL,Butler NS,Harty JT

更新日期：2014-01-16 00:00:00

abstract：:In this study, the haemolytic activities of Astragalus membranaceus saponins (AMS) and its adjuvant potentials on the cellular and humoral immune responses of ICR mice against OVA were evaluated. We determined the haemolytic activity of AMS using 0.5% rabbit red blood cell. AMS showed a slight haemolytic effect, with ...

journal_title：Vaccine

authors： Yang ZG,Sun HX,Fang WH

更新日期：2005-10-25 00:00:00

abstract：:Ten years have elapsed since routine vaccination of infants and of 12-year-old adolescent was implemented in Italy. In this period, evidence has accumulated on the epidemiological impact of universal immunisation. Coverage is on average >90% and is >or=95% in many areas of the country. Incidence of acute hepatitis B, ...

journal_title：Vaccine

authors： Bonanni P,Pesavento G,Bechini A,Tiscione E,Mannelli F,Benucci C,Nostro AL

更新日期：2003-01-30 00:00:00

abstract：:Several publications have reported recently the apparently successful use of human diploid cell rabies vaccine (HDCV) in volumes of less than the 6 X 1.0 cm3 dosage schedule currently recommended by the World Health Organization for post-exposure rabies prophylaxis. The newer proposed treatments are advocated to econo...

journal_title：Vaccine

authors： Gross EM,Bearman JE

更新日期：1985-09-01 00:00:00

abstract：:TA-CIN is a vaccine that comprises the human papillomavirus (HPV) type 16 L2, E6 and E7 as a single fusion protein. In a mouse model, TA-CIN effectively prevented outgrowth of HPV16-positive tumour cells. To assess the safety and immunogenicity of TA-CIN, a dose escalating (26, 128, 533 micro g), double blind and plac...

journal_title：Vaccine

authors： de Jong A,O'Neill T,Khan AY,Kwappenberg KM,Chisholm SE,Whittle NR,Dobson JA,Jack LC,St Clair Roberts JA,Offringa R,van der Burg SH,Hickling JK

更新日期：2002-10-04 00:00:00

abstract：:The conventional treatment for paracoccidioidomycosis, the most prevalent mycosis in Latin America, involves long periods of therapy resulting in sequels and high frequency of relapses. The search for new alternatives of treatment is necessary. Previously, we have demonstrated that the hsp65 gene from Mycobacterium le...

journal_title：Vaccine

authors： Ribeiro AM,Bocca AL,Amaral AC,Souza AC,Faccioli LH,Coelho-Castelo AA,Figueiredo F,Silva CL,Felipe MS

更新日期：2010-02-10 00:00:00

abstract：OBJECTIVE:In response to the emergence of influenza viruses with pandemic potential, we evaluated a swine-origin influenza A/H3N2 variant (H3N2v) vaccine in children. STUDY DESIGN:This multicenter phase II open-label study assessed the safety and immunogenicity of two doses, 21 days apart, of investigational unadjuvan...

journal_title：Vaccine

authors： Munoz FM,Anderson EJ,Bernstein DI,Harrison CJ,Pahud B,Anderson E,Creech CB,Berry AA,Kotloff KL,Walter EB,Atmar RL,Bellamy AR,Chang S,Keitel WA

更新日期：2019-08-23 00:00:00

abstract：BACKGROUND:Nasal vaccination is considered to be a promising alternative for parenteral vaccination against influenza virus as it is non-invasive and offers the opportunity to elicit strong antigen-specific responses both systemic and locally at the port of entry of the pathogen. Previous studies showed that non-living...

journal_title：Vaccine

authors： Keijzer C,Haijema BJ,Meijerhof T,Voorn P,de Haan A,Leenhouts K,van Roosmalen ML,van Eden W,Broere F

更新日期：2014-05-19 00:00:00

abstract：:Capsular polysaccharides are important virulence factors of Streptococcus pneumoniae. The polysaccharide has been used as a component of vaccines against pneumococcal diseases either as plain polysaccharide or better conjugated to a protein. The last one is the vaccine of choice to target child protection. The immune ...

journal_title：Vaccine

authors： Chang J,Serrano Y,Garrido R,Rodríguez LM,Pedroso J,Cardoso F,Valdés Y,García D,Fernández-Santana V,Verez-Bencomo V

更新日期：2012-11-19 00:00:00

abstract：BACKGROUND:Vaccinations are an effective choice to stop disease outbreaks, including COVID-19. There is little research on individuals' COVID-19 vaccination decision-making. OBJECTIVE:We aimed to determine individual preferences for COVID-19 vaccinations in China, and to assess the factors influencing vaccination deci...

journal_title：Vaccine

authors： Leng A,Maitland E,Wang S,Nicholas S,Liu R,Wang J

更新日期：2021-01-08 00:00:00

abstract：:The continuous outbreaks of fatal Newcastle disease (ND) in commercial poultry flocks demonstrate that current vaccination strategies are not fully efficacious and should be improved by new generation of vaccines. In this context, maternally immune conventional layer chickens were vaccinated in ovo with a turkey herpe...

journal_title：Vaccine

authors： Rauw F,Gardin Y,Palya V,Anbari S,Lemaire S,Boschmans M,van den Berg T,Lambrecht B

更新日期：2010-01-08 00:00:00

abstract：:Nine pigs were given a single inoculum of 100 microg of the all-D retro peptide corresponding to the immunodominant GH loop encompassing residues 141-159 of capsid protein VP1 of foot-and-mouth disease virus serotype A, sub-type 12. The peptide was conjugated to activated keyhole limpet haemocyanin and oil-adjuvanted ...

journal_title：Vaccine

authors： Nargi F,Kramer E,Mezencio J,Zamparo J,Whetstone C,Van Regenmortel MH,Briand JP,Muller S,Brown F

更新日期：1999-07-16 00:00:00

abstract：:To study the kinetics of humoral as well as cellular immunity to measles and to test for associated immunosuppression 124 12 month old children were studied twice, before routine MMR and either 14, 22, 30, or 38 days after vaccination. Plaque reduction neutralization (PRN) titres were determined at these time points a...

journal_title：Vaccine

authors： Pabst HF,Spady DW,Carson MM,Stelfox HT,Beeler JA,Krezolek MP

更新日期：1997-01-01 00:00:00

abstract：:C57BL/6 (B6) mice were immunized with a highly antigenic 10-mer peptide (P12-10), which is encoded by the murine AIDS (MAIDS) defective virus gag p12 gene, emulsified in incomplete Freund's adjuvant (ICFA). One week later, the mice were inoculated with the MAIDS virus to see if the immunization affects progression of ...

journal_title：Vaccine

authors： Mizuochi T,Horino A,Uchida T

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVES:With the re-emergence of chikungunya virus (CHIKV) in an explosive form and in the absence of a commercially available vaccine, we aimed to develop candidate vaccines employing recombinant E2 protein or chemically inactivated whole virus. DESIGN AND METHODS:E2 gene of CHIKV isolate of ECSA genotype was clon...

journal_title：Vaccine

authors： Kumar M,Sudeep AB,Arankalle VA

更新日期：2012-09-21 00:00:00