Unequal access to vaccines in the WHO European Region during the A(H1N1) influenza pandemic in 2009.

Abstract:

:In a severe pandemic, rapid production and deployment of vaccines will potentially be critical in mitigating the impact on populations and essential services. We compared access to vaccines and timing of delivery relative to identification of A(H1N1)pdm09 and the geographic progression of the pandemic in the WHO European Region in order to identify gaps in provision. Information on vaccine procurement and donations was collected through a web-based survey conducted in all 53 member states of the Region. Among the 51 countries responding to the survey, the majority (84%) implemented vaccination campaigns against A(H1N1)pdm09. However, time of vaccine receipt and number of doses varied substantially across the region, with delayed access in many countries especially in those in the lowest income range. Improving access to influenza vaccines in low resource countries and solving issues of product liability should help reduce inequalities and operational challenges arising during a future public health crisis.

journal_name

Vaccine

journal_title

Vaccine

authors

Jorgensen P,Wasley A,Mereckiene J,Cotter S,Weber JT,Brown CS

doi

10.1016/j.vaccine.2013.06.082

subject

Has Abstract

pub_date

2013-08-28 00:00:00

pages

4060-2

issue

38

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(13)00892-X

journal_volume

31

pub_type

杂志文章

相关文献

VACCINE文献大全
  • Enteral immunization and challenge of volunteers given enterotoxigenic E. coli CFA/II encapsulated in biodegradable microspheres.

    abstract::The development of a safe and effective vaccine against enterotoxigenic Escherichia coli (ETEC) would be useful for travellers and for young children in endemic areas. A feasibility study of an enteral ETEC vaccine prototype consisting of colonization factor antigen II (CFA/II), containing two component antigens CS1 a...

    journal_title:Vaccine

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0264-410x(94)80038-2

    authors: Tacket CO,Reid RH,Boedeker EC,Losonsky G,Nataro JP,Bhagat H,Edelman R

    更新日期:1994-11-01 00:00:00

  • Impact of MenBvac, an outer membrane vesicle (OMV) vaccine, on the meningococcal carriage.

    abstract::The aim of the study was to analyze the impact of MenBvac, an outer membrane vesicle (OMV) vaccine against P1.7,16 strains, on meningococcal carriage. During a B:14:P1.7,16/ST-32 outbreak in Normandy (France), children aged 1-7 years were randomly selected to participate in the study. Among the 1082 volunteers, there ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2013.06.080

    authors: Delbos V,Lemée L,Bénichou J,Berthelot G,Deghmane AE,Leroy JP,Houivet E,Hong E,Taha MK,Caron F,B14 STOP study group.

    更新日期:2013-09-13 00:00:00

  • Studies on the usefulness of intranasal inactivated influenza vaccines.

    abstract::Intranasal inactivated influenza vaccines have the advantage over parenteral vaccines in that they are not associated with the pain of an injection. However, they would be most useful if they were available for all age groups, including high-risk groups, and also would provide cross-protection against variant virus st...

    journal_title:Vaccine

    pub_type: 杂志文章,评审

    doi:10.1016/j.vaccine.2010.05.019

    authors: Tamura S

    更新日期:2010-08-31 00:00:00

  • Single-chain antibodies produced by phage display against the C-terminal 19 kDa region of merozoite surface protein-1 of Plasmodium yoelii reduce parasite growth following challenge.

    abstract::Antibodies have the potential to be therapeutic reagents for malaria. Here we describe the production of a novel phage antibody display library against the C-terminal 19kDa region of the Plasmodium yoelii YM merozoite surface protein-1 (MSP1(19)). In vivo studies against homologous lethal malaria challenge show an ant...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/s0264-410x(02)00197-4

    authors: Vukovic P,Chen K,Qin Liu X,Foley M,Boyd A,Kaslow D,Good MF

    更新日期:2002-06-21 00:00:00

  • Distribution of adsorbed antigen in mono-valent and combination vaccines.

    abstract::The distribution of alpha-casein, bovine serum albumin (BSA), myoglobin and recombinant protective antigen (rPA) in mono-valent and combination vaccines containing aluminum hydroxide adjuvant was studied by fluorescence microscopy and flow cytometry. Green and red fluorescent probes were conjugated to the antigens. Ad...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2003.10.040

    authors: Morefield GL,HogenEsch H,Robinson JP,Hem SL

    更新日期:2004-05-07 00:00:00

  • Enhancing the role of vaccines in combatting antimicrobial resistance.

    abstract::Interest in addressing antimicrobial resistance (AMR) has grown recently but little effort has been made to consider how existing and new vaccines could impact on AMR. A 2017 Chatham House meeting considered the role of vaccines and how to demonstrate their value through their impact on AMR. Ways existing vaccines hav...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2017.09.053

    authors: Clift C,Salisbury DM

    更新日期:2017-12-04 00:00:00

  • The site of administration influences both the type and the magnitude of the immune response induced by DNA vaccine electroporation.

    abstract::We investigated the influence of the site of administration of DNA vaccine on the induced immune response. DNA vaccines were administered by electroporation at three different sites: tibial cranial muscle, abdominal skin and ear pinna. Aiming to draw general conclusions about DNA vaccine delivery, we successively used...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2015.05.005

    authors: Vandermeulen G,Vanvarenberg K,De Beuckelaer A,De Koker S,Lambricht L,Uyttenhove C,Reschner A,Vanderplasschen A,Grooten J,Préat V

    更新日期:2015-06-22 00:00:00

  • Vaccination of volunteers with low-dose, live-attenuated, dengue viruses leads to serotype-specific immunologic and virologic profiles.

    abstract::There are currently no vaccines or therapeutics to prevent dengue disease which ranges in severity from asymptomatic infections to life-threatening illness. The National Institute of Allergy and Infectious Diseases (NIAID) Division of Intramural Research has developed live, attenuated vaccines to each of the four deng...

    journal_title:Vaccine

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.vaccine.2013.05.075

    authors: Lindow JC,Durbin AP,Whitehead SS,Pierce KK,Carmolli MP,Kirkpatrick BD

    更新日期:2013-07-18 00:00:00

  • Differences between vaccinated and unvaccinated women explain increase in non-vaccine-type human papillomavirus in unvaccinated women after vaccine introduction.

    abstract::The aim of this study was to determine whether an observed increase in non-vaccine-type human papillomavirus (HPV) in unvaccinated women during the first eight years after vaccine introduction may be explained by differences in demographics or sexual behaviors, instead of type replacement. We analyzed data from three ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2017.11.005

    authors: Ding L,Widdice LE,Kahn JA

    更新日期:2017-12-19 00:00:00

  • Quantifying outcome misclassification in multi-database studies: The case study of pertussis in the ADVANCE project.

    abstract:BACKGROUND:The Accelerated Development of VAccine beNefit-risk Collaboration in Europe (ADVANCE) is a public-private collaboration aiming to develop and test a system for rapid benefit-risk (B/R) monitoring of vaccines using European healthcare databases. Event misclassification can result in biased estimates. Using di...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2019.07.045

    authors: Gini R,Dodd CN,Bollaerts K,Bartolini C,Roberto G,Huerta-Alvarez C,Martín-Merino E,Duarte-Salles T,Picelli G,Tramontan L,Danieli G,Correa A,McGee C,Becker BFH,Switzer C,Gandhi-Banga S,Bauwens J,van der Maas NAT,Spiteri

    更新日期:2020-12-22 00:00:00

  • Human papillomavirus-like particles mediate functional delivery of plasmid DNA to antigen presenting cells in vivo.

    abstract::Because recombinant empty viral capsids are potentially attractive vectors for gene therapy, here we examined the ability of human papillomavirus (HPV) virus-like particles (VLPs) to mediate delivery and expression of DNA plasmids in vitro and in vivo. VLP-mediated delivery and expression of a GFP reporter construct i...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2007.01.067

    authors: Malboeuf CM,Simon DA,Lee YE,Lankes HA,Dewhurst S,Frelinger JG,Rose RC

    更新日期:2007-04-30 00:00:00

  • Long-term effectiveness of zoster vaccine live for postherpetic neuralgia prevention.

    abstract:BACKGROUND:Postherpetic neuralgia (PHN) occurs in 5-30% of individuals with herpes zoster (HZ) and is characterized by long-lasting pain. Zoster vaccine live (ZVL) is licensed for people 50 years and older to prevent HZ and PHN. This study evaluated vaccine effectiveness (VE) of ZVL against PHN. METHODS:We conducted a...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2019.07.004

    authors: Klein NP,Bartlett J,Fireman B,Marks MA,Hansen J,Lewis E,Aukes L,Saddier P

    更新日期:2019-08-23 00:00:00

  • Genetic fusion of proteins to the SIV Tat protein enhances their immunogenicity.

    abstract::The potential of genetically fusing recombinant proteins to the simian immunodeficiency virus (SIV) Tat protein has been investigated. The recombinant SIV Tat protein was initially expressed in very low amounts in E. coli, but optimization of the coding sequence for translation in the bacterial host significantly impr...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2005.09.012

    authors: Chen YH,Diassiti A,Randall RE

    更新日期:2006-02-06 00:00:00

  • Low mortality after mild measles infection compared to uninfected children in rural West Africa.

    abstract:BACKGROUND:It has been assumed that measles infection may be associated with persistent immune suppression and long-term excess mortality. However, few community studies of mortality after measles infection have been carried out. We examined long-term mortality for measles cases, sub-clinical measles cases, and uninfec...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/s0264-410x(02)00430-9

    authors: Aaby P,Simondon F,Samb B,Cisse B,Jensen H,Lisse IM,Soumaré M,Whittle H

    更新日期:2002-11-22 00:00:00

  • Characterization of Schistosoma mansoni 44.7/56.8 kDa egg antigens recognized by human monoclonal antibodies which induce protection against experimental infection and proliferation of peripheral blood mononuclear cells from schistosomiasis patients.

    abstract::We described here the characterization of Schistosoma mansoni egg antigens recognized by human monoclonal antibodies B10 (HmAb-B10) and D5 (HmAb-D5). SDS-PAGE and Western blot analysis revealed that these monoclonals recognized two antigens of M W 44.7/56.8 kDa, with pI of 7.0 and 7.8, respectively. The passive transf...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/s0264-410x(96)00305-2

    authors: Hirsch C,Almeida CA,Doughty BL,Goes AM

    更新日期:1997-06-01 00:00:00

  • Oral immunization of adult volunteers with microencapsulated enterotoxigenic Escherichia coli (ETEC) CS6 antigen.

    abstract::As a step in the development of an oral vaccine against ETEC, we evaluated the safety and immunogenicity of CS6, a polymeric protein commonly found on the surface of ETEC. Formulations included 1 and 5mg doses of CS6, either encapsulated in biodegradable polymer poly(D, L)-lactide-co-glycolide (PLG), or as free protei...

    journal_title:Vaccine

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0264-410x(02)00613-8

    authors: Katz DE,DeLorimier AJ,Wolf MK,Hall ER,Cassels FJ,van Hamont JE,Newcomer RL,Davachi MA,Taylor DN,McQueen CE

    更新日期:2003-01-17 00:00:00

  • Vaccination-induced HI antibody to influenza A(H1N1) viruses in poorly primed adults under circumstances of low antigenic drift.

    abstract::In Autumn 1990, trivalent split influenza virus vaccine containing A/Taiwan/1/86(H1N1) was used to immunize healthy female employees (n = 104). The 11-12 amino acid differences in the HA1 domain of virus haemagglutinin between A/Taiwan/1/86 and representative epidemic H1N1 strains in Finland in 1991 did not result in ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/0264-410x(93)90126-i

    authors: Pyhälä R,Kinnunen L,Kumpulainen V,Ikonen N,Kleemola M,Cantell K

    更新日期:1993-01-01 00:00:00

  • Feasibility of case-control and test-negative designs to evaluate dengue vaccine effectiveness in Malaysia.

    abstract:BACKGROUND:The world's first dengue vaccine [Dengvaxia; Sanofi Pasteur] was licensed in 2015 and others are in development. Real-world evaluations of dengue vaccines will therefore soon be needed. We assessed feasibility of case control (CC) and test-negative (TN) design studies for dengue vaccine effectiveness by meas...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2019.07.083

    authors: Nealon J,Lim WY,Moureau A,Linus Lojikip S,Junus S,Kumar S,Nachiappan JP,Devi Sekaran S,Radigue C,Cowling BJ,Ochiai RL,Hss AS

    更新日期:2019-09-16 00:00:00

  • Developing an HPV vaccine to prevent cervical cancer and genital warts.

    abstract::The challenges of the journey from target identification through development of a prophylactic quadrivalent human papillomavirus (HPV) vaccine have been met in Gardasil. Cervical cancer is the second leading cause of cancer-related death in women worldwide. Approximately 70% of cervical cancer is caused by infection w...

    journal_title:Vaccine

    pub_type: 杂志文章,评审

    doi:10.1016/j.vaccine.2007.01.013

    authors: Bryan JT

    更新日期:2007-04-20 00:00:00

  • Immunogenicity and protective efficacy in monkeys of purified inactivated Vero-cell SARS vaccine.

    abstract:BACKGROUND:In 2003, severe acute respiratory syndrome (SARS) resulted in hundreds of infections and deaths globally. We aim to assess immunogenicity and protective efficacy of purified inactivated Vero-cell SARS vaccine in monkeys. METHODS:The cultures of SARS coronavirus (SARS-CoV) BJ-01 strain infected Vero cells we...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2005.06.038

    authors: Qin E,Shi H,Tang L,Wang C,Chang G,Ding Z,Zhao K,Wang J,Chen Z,Yu M,Si B,Liu J,Wu D,Cheng X,Yang B,Peng W,Meng Q,Liu B,Han W,Yin X,Duan H,Zhan D,Tian L,Li S,Wu J,Tan G,Li Y,Li Y,Liu Y,Liu H,Lv F

    更新日期:2006-02-13 00:00:00

  • The benefits of redesigning Benin's vaccine supply chain.

    abstract:INTRODUCTION:New vaccine introductions have put strains on vaccine supply chains around the world. While increasing storage and transportation may be the most straightforward options, it is also important to consider what financial and operational benefits can be incurred. In 2012, suboptimal vaccine coverage and impen...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2014.04.090

    authors: Brown ST,Schreiber B,Cakouros BE,Wateska AR,Dicko HM,Connor DL,Jaillard P,Mvundura M,Norman BA,Levin C,Rajgopal J,Avella M,Lebrun C,Claypool E,Paul P,Lee BY

    更新日期:2014-07-07 00:00:00

  • Immunogenicity of virus-like particles containing modified human immunodeficiency virus envelope proteins.

    abstract::Extensive glycosylation and variable loops of the HIV envelope protein (Env) are reported to shield some neutralizing epitopes. Here, we investigated the immunogenicity of mutated HIV Envs presented in virus-like particles (VLPs). We immunized mice with simian human immunodeficiency virus (SHIV) VLPs containing mutant...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2007.01.107

    authors: Quan FS,Sailaja G,Skountzou I,Huang C,Vzorov A,Compans RW,Kang SM

    更新日期:2007-05-10 00:00:00

  • Report from Working Group 3 (the Czech Republic, Denmark, Finland, Norway, The Netherlands, Slovakia, Sweden and the UK).

    abstract::The Czech Republic, Denmark, Finland, Norway, the Netherlands, Slovakia, Sweden and the UK all have very low HBsAg carrier rates; in the Scandinavian countries, for instance, carrier rates are on the order of 0.05%. Most countries in this group are unconvinced that the carrier rates and the burden of disease caused by...

    journal_title:Vaccine

    pub_type:

    doi:10.1016/s0264-410x(98)00299-0

    authors: Iwarson S

    更新日期:1998-11-01 00:00:00

  • Human papillomavirus vaccine effectiveness by number of doses: Systematic review of data from national immunization programs.

    abstract:BACKGROUND:Human papillomavirus (HPV) vaccines were first licensed as a three-dose series; a two-dose series is now recommended in some age groups and there is interest in possible one-dose vaccination. METHODS:We conducted a systematic literature review of HPV vaccine effectiveness by number of doses, including asses...

    journal_title:Vaccine

    pub_type: 杂志文章,评审

    doi:10.1016/j.vaccine.2018.01.057

    authors: Markowitz LE,Drolet M,Perez N,Jit M,Brisson M

    更新日期:2018-08-06 00:00:00

  • Outer membrane PhoE protein of Escherichia coli as a carrier for foreign antigenic determinants: immunogenicity of epitopes of foot-and-mouth disease virus.

    abstract::Outer membrane protein PhoE of Escherichia coli was used for the expression of antigenic determinants of foot-and-mouth disease virus. Five hybrid PhoE proteins were constructed containing different combinations of two antigenic determinants of VP1 protein of the virus. The hybrid proteins were expressed in two E. col...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/0264-410x(90)90184-n

    authors: Agterberg M,Adriaanse H,Lankhof H,Meloen R,Tommassen J

    更新日期:1990-02-01 00:00:00

  • Ultraviolet-C irradiation for inactivation of viruses in foetal bovine serum.

    abstract::Foetal Bovine Serum (FBS) and porcine trypsin are one of the essential raw materials used in the manufacturing of cell culture based viral vaccines. Being from animal origin, these raw materials can potentially contaminate the final product by known or unknown adventitious agents. The issue is more serious in case of ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2018.06.008

    authors: Vaidya V,Dhere R,Agnihotri S,Muley R,Patil S,Pawar A

    更新日期:2018-07-05 00:00:00

  • Characterization of West Nile virus live vaccine candidates attenuated by capsid deletion mutations.

    abstract::Protein C deletion mutants of West Nile virus (WNV) were evaluated for their potential use as live virus vaccine candidates in vivo. Double and triple mutants carrying small deletions and second-site point mutations, as well as mutants with large deletions of 36 and 37 amino acid residues were tested in a stringent mo...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2010.06.045

    authors: Schlick P,Kofler RM,Schittl B,Taucher C,Nagy E,Meinke A,Mandl CW

    更新日期:2010-08-16 00:00:00

  • Characterization of a concealed antigen Hq05 from the hard tick Haemaphysalis qinghaiensis and its effect as a vaccine against tick infestation in sheep.

    abstract::Positive clone Hq05 of Haemaphysalis qinghaiensis (named following those cDNA clones cloned from the tick before) was obtained by differentially screening of a cDNA library of the tick with rabbit anti-tick salivary gland serum and rabbit anti-tick saliva serum. Hq05 contains an open reading frame (ORF) of 540bp that ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2008.10.067

    authors: Gao J,Luo J,Fan R,Schulte-Spechtel UC,Fingerle V,Guan G,Zhao H,Li Y,Ren Q,Ma M,Liu Z,Liu A,Dang Z,Sugimoto C,Yin H

    更新日期:2009-01-14 00:00:00

  • Using QPCR to assign infectious potencies to adenovirus based vaccines and vectors for gene therapy: toward a universal method for the facile quantitation of virus and vector potency.

    abstract::The assignment of infectious potency to test articles of adenovirus has been conducted mainly using classical end-point dilution methods, which rely on virus induced cytopathology to reveal the presence of infectious virus. These assays suffer the disadvantages of labor intensity, duration, throughput restriction and ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2005.04.023

    authors: Wang F,Puddy AC,Mathis BC,Montalvo AG,Louis AA,McMackin JL,Xu J,Zhang Y,Tan CY,Schofield TL,Wolf JJ,Lewis JA

    更新日期:2005-08-22 00:00:00

  • Porcine Reproductive and Respiratory Syndrome Virus isolates differ in their susceptibility to neutralization.

    abstract::Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is highly heterogenic. This heterogeneity has an effect on antigenic composition of PRRSV and might create differences in sensitivity to neutralization between isolates. The sensitivity to neutralization could be an important feature of PRRSV isolates because...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2011.07.076

    authors: Martínez-Lobo FJ,Díez-Fuertes F,Simarro I,Castro JM,Prieto C

    更新日期:2011-09-16 00:00:00