Expression of cytokine genes following pre- and post-hatch immunization of chickens with herpesvirus of turkeys.

abstract：:Mice immunized with plasmid DNA encoding Nef regulatory protein of human immunodeficiency virus type 1 developed high levels of anti-Nef antibodies. After 4 intramuscular injections of 100 microg plasmid DNA, anti-Nef antibodies reached titers up to 2 x 10(4). A significant specific antibody response was maintained fo...

journal_title：Vaccine

authors： Moureau C,Moynier M,Kavsan V,Montagnier L,Bahraoui E

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVES:HIV-infected children have poor responses to inactivated influenza vaccines. Live vaccines (LAIVs) are highly efficacious in children, but they are not used in HIV-infected children du e to limited information. We investigated the safety, immunogenicity and viral shedding of LAIV4 in HIV-infected compared wi...

journal_title：Vaccine

authors： Curtis D,Ning MF,Armon C,Li S,Weinberg A

更新日期：2015-09-11 00:00:00

abstract：:Hybrid cell vaccines of autologous tumour cells fused with allogenic dendritic cells (DC) combine the tumour's antigenicity with the immune-stimulatory capacity of mature dendritic cells and allogenic MHC class II molecules to activate T cell help and induce tumour-specific cytotoxic T cells. This concept was tested i...

journal_title：Vaccine

authors： Trefzer U,Herberth G,Wohlan K,Milling A,Thiemann M,Sharav T,Sparbier K,Sterry W,Walden P

更新日期：2005-03-18 00:00:00

abstract：:Epidemic influenza occurs annually throughout the world and is accompanied by excess morbidity and mortality. Increasing the antigen content and topical administration of vaccine are two strategies being explored to improve the immune responses to trivalent inactivated influenza vaccine (TIV). We conducted a randomize...

journal_title：Vaccine

authors： Atmar RL,Keitel WA,Cate TR,Munoz FM,Ruben F,Couch RB

更新日期：2007-07-20 00:00:00

abstract：:In 2003, a nationwide cross-sectional study was conducted to assess the current influenza vaccination coverage of the adult population of Germany, especially in persons belonging to defined target groups. Of 666 surveyed persons, 190 (adjusted 24%) had received influenza vaccination and 419 participants belonged to at...

journal_title：Vaccine

authors： Wiese-Posselt M,Leitmeyer K,Hamouda O,Bocter N,Zöllner I,Haas W,Ammon A

更新日期：2006-03-24 00:00:00

abstract：:Malignant catarrhal fever (MCF) is a fatal lymphoproliferative disease of cattle that, in East Africa, results from transmission of the causative virus, alcelaphine herpesvirus 1 (AlHV-1), from wildebeest. A vaccine field trial involving an attenuated AlHV-1 virus vaccine was performed over two wildebeest calving seas...

journal_title：Vaccine

authors： Lankester F,Russell GC,Lugelo A,Ndabigaye A,Mnyambwa N,Keyyu J,Kazwala R,Grant D,Percival A,Deane D,Haig DM,Cleaveland S

更新日期：2016-02-03 00:00:00

abstract：BACKGROUND:Two conserved pneumococcal proteins, pneumolysin toxoid (dPly) and pneumococcal histidine triad protein D (PhtD), combined with 10 polysaccharide conjugates from the pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) in two investigational pneumococcal vaccine (PHiD-CV/dPl...

journal_title：Vaccine

authors： Odutola A,Ota MOC,Antonio M,Ogundare EO,Saidu Y,Owiafe PK,Worwui A,Idoko OT,Owolabi O,Kampmann B,Greenwood BM,Alderson M,Traskine M,Swinnen K,Verlant V,Dobbelaere K,Borys D

更新日期：2019-05-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) is the most common cause of viral bronchiolitis and pneumonia in children. The present study compares the level of attenuation, genetic stability and efficacy of three conditional-lethal temperature-sensitive (ts) mutants of the RSV A2 wild-type virus, designated ts-1, ts-1-NG1, and t...

journal_title：Vaccine

authors： Crowe JE Jr,Collins PL,London WT,Chanock RM,Murphy BR

更新日期：1993-11-01 00:00:00

abstract：:The levels of antibody against measles, mumps, and rubella were determined at 5-6 years postimmunization in 468 children vaccinated with two different trivalent vaccines. The proportions of children without detectable antibody levels were 12 and 3.6% for measles (p < 0.001), 14.9 and 7% for mumps (p = 0.006), and 3.3 ...

journal_title：Vaccine

authors： Boulianne N,De Serres G,Ratnam S,Ward BJ,Joly JR,Duval B

更新日期：1995-11-01 00:00:00

abstract：:With declining influenza vaccine coverage in the elderly in recent years in France, we aimed at assessing the benefits of seasonal influenza vaccination, based on available data for observed mortality, vaccine coverage and vaccine effectiveness. To estimate the annual number of deaths avoided by vaccination in the peo...

journal_title：Vaccine

authors： Bonmarin I,Belchior E,Lévy-Bruhl D

更新日期：2015-02-25 00:00:00

abstract：:The use of gene guns in ballistically delivering DNA vaccine coated gold micro-particles to skin can potentially damage targeted cells, therefore influencing transfection efficiencies. In this paper, we assess cell death in the viable epidermis by non-invasive near infrared two-photon microscopy following micro-partic...

journal_title：Vaccine

authors： Raju PA,McSloy N,Truong NK,Kendall MA

更新日期：2006-05-22 00:00:00

abstract：:Optimal protection against malaria may require induction of high levels of protective antibody and CD8(+) and CD4(+) T cell responses. In humans, malaria DNA vaccines elicit CD8(+) cytotoxic T cells (CTL) and IFNgamma responses as measured by short-term (ex vivo) ELISPOT assays, and recombinant proteins elicit antibod...

journal_title：Vaccine

authors： Epstein JE,Charoenvit Y,Kester KE,Wang R,Newcomer R,Fitzpatrick S,Richie TL,Tornieporth N,Heppner DG,Ockenhouse C,Majam V,Holland C,Abot E,Ganeshan H,Berzins M,Jones T,Freydberg CN,Ng J,Norman J,Carucci DJ,Cohen J

更新日期：2004-04-16 00:00:00

abstract：:Presence of maternally-derived antibodies at time of immunization is known to often interfere with active infant immunization, although with variable degrees of clinical significance. In order to progressively decipher the rules that form the basis for these inhibitory effects on infant vaccine responses, two antigens...

journal_title：Vaccine

authors： Siegrist CA,Córdova M,Brandt C,Barrios C,Berney M,Tougne C,Kovarik J,Lambert PH

更新日期：1998-08-01 00:00:00

abstract：:Oral and inactivated poliomyelitis vaccines (OPV and IPV), were given to 160 children two months old, in a low income population at Rio de Janeiro. The vaccination was repeated 2 and 4 months later, always in association with diphtheria, tetanus and pertussis (DPT) vaccine. Blood specimens were collected before vaccin...

journal_title：Vaccine

authors： Schatzmayr HG,Maurice Y,Fujita M,de Fillipis AM

更新日期：1986-06-01 00:00:00

abstract：:Neutralizing antibodies play an essential part in antiviral immunity and are instrumental in preventing or modulating viral diseases. Polyclonal antibody preparations are increasingly being replaced by highly potent monoclonal antibodies (mAbs). Cocktails of mAbs and bispecific constructs can be used to simultaneously...

journal_title：Vaccine

authors： Both L,Banyard AC,van Dolleweerd C,Wright E,Ma JK,Fooks AR

更新日期：2013-03-15 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the impact of introduction of 9vHPV vaccine on HPV vaccination uptake (doses per capita) and initiation (≥1 doses), completion (≥3 doses) and compliance (≥3 doses within 12 months) by adolescents. METHODS:We used a retrospective cohort analysis using North Carolin...

journal_title：Vaccine

authors： Trogdon JG,Shafer P,Lindsay B,Coyne-Beasley T

更新日期：2018-02-28 00:00:00

abstract：BACKGROUND:Vaccination against Haemophilus influenzae type b (Hib) is included in routine pediatric immunization schedule in the United States. Previous vaccine shortages have created the need for additional options for Hib vaccination. METHODS:This phase III, randomized, multi-centered study (NCT01000974) evaluated t...

journal_title：Vaccine

authors： Klein NP,Abu-Elyazeed R,Cornish M,Leonardi ML,Weiner LB,Silas PE,Grogg SE,Varman M,Frenck RW,Cheuvart B,Baine Y,Miller JM,Leyssen M,Mesaros N,Roy-Ghanta S

更新日期：2017-06-16 00:00:00

abstract：:The rectum as an effective site for induction of systemic and local immunity has received little attention. Rectal immunization with microspheres-containing ovalbumin (MS-OVA) was tested for its ability to elicit systemic and mucosal immune responses. Rectal immunization with MS-OVA enhanced both Th2 dominant OVA-spec...

journal_title：Vaccine

authors： Nakase H,Okazaki K,Tabata Y,Uchida K,Uose S,Ohana M,Nishi T,Watanabe T,Matsuura M,Hisatsune H,Matsumura K,Itoh T,Kawanami C,Chiba T

更新日期：2001-11-12 00:00:00

abstract：:The trivalent inactivated vaccine (TIV) is used to prevent seasonal influenza virus infection in humans, however, the immunogenicity of this vaccine may be influenced by the priming effect of previous influenza vaccinations or exposure to antigenically related influenza viruses. The current study examines the immunoge...

journal_title：Vaccine

authors： Wang S,Parker C,Taaffe J,Solórzano A,García-Sastre A,Lu S

更新日期：2008-07-04 00:00:00

abstract：:A major challenge for poultry vaccination is the design of vaccines that protect against multiple pathogens via a single protective dose delivered through mass vaccination methods. In this investigation, we examined herpesvirus of turkeys (HVT) as a vaccine vector for delivery of haemagglutinin (HA) antigen of highly ...

journal_title：Vaccine

authors： Li Y,Reddy K,Reid SM,Cox WJ,Brown IH,Britton P,Nair V,Iqbal M

更新日期：2011-10-26 00:00:00

abstract：:Concerns over migratory bison (Bison bison) at Yellowstone National Park transmitting brucellosis (Brucella abortus) to cattle herds on adjacent lands led to proposals for bison vaccination. We developed an individual-based model to evaluate how brucellosis infection might respond under alternate vaccination strategie...

journal_title：Vaccine

authors： Treanor JJ,Johnson JS,Wallen RL,Cilles S,Crowley PH,Cox JJ,Maehr DS,White PJ,Plumb GE

更新日期：2010-10-01 00:00:00

abstract：:Protein C deletion mutants of West Nile virus (WNV) were evaluated for their potential use as live virus vaccine candidates in vivo. Double and triple mutants carrying small deletions and second-site point mutations, as well as mutants with large deletions of 36 and 37 amino acid residues were tested in a stringent mo...

journal_title：Vaccine

authors： Schlick P,Kofler RM,Schittl B,Taucher C,Nagy E,Meinke A,Mandl CW

更新日期：2010-08-16 00:00:00

abstract：:T-lymphocyte responses to influenza vaccination were measured in healthy young and older adult volunteers. All participants were vaccinated with the 1995-96 trivalent influenza vaccine. Cytokine and granzyme B levels were measured in peripheral blood mononuclear cells (PBMC) cultures after virus stimulation, prior to ...

journal_title：Vaccine

authors： McElhaney JE,Upshaw CM,Hooton JW,Lechelt KE,Meneilly GS

更新日期：1998-11-01 00:00:00

abstract：:Influenza is an important public health issue and schools play an important part in preventing influenza outbreaks. However, little is known about teachers' knowledge and attitudes toward influenza and vaccination. The purposes of this project were to assess preservice and early career teachers' knowledge and attitude...

journal_title：Vaccine

authors： Vaughn AR,Johnson ML

更新日期：2018-11-19 00:00:00

abstract：:Seasonal influenza epidemics are associated with high morbidity and mortality particularly in high-risk patients. Conventionally administered influenza vaccines show reduced efficacy in populations with weakened immune systems such as solid-organ transplant patients. This study assesses the safety and immunogenicity o...

journal_title：Vaccine

authors： Morelon E,Pouteil Noble C,Daoud S,Cahen R,Goujon-Henry C,Weber F,Laurent PE,Kaiserlian D,Nicolas JF

更新日期：2010-10-04 00:00:00

abstract：:Immunization of pregnant women against influenza is a promising strategy to protect the mother, fetus, and young infant from influenza-related diseases. The burden of influenza during pregnancy, the vaccine immunogenicity during this period, and the robust influenza vaccine safety database underpin recommendations tha...

journal_title：Vaccine

authors： Ortiz JR,Neuzil KM,Ahonkhai VI,Gellin BG,Salisbury DM,Read JS,Adegbola RA,Abramson JS

更新日期：2012-11-26 00:00:00

abstract：:Optimized DNA vectors were constructed comprising the proteome of SIV including the structural, enzymatic, regulatory, and accessory proteins. In addition to native antigens as produced by the virus, fusion proteins and modified antigens with altered secretion, cellular localization and stability characteristics were ...

journal_title：Vaccine

authors： Kulkarni V,Jalah R,Ganneru B,Bergamaschi C,Alicea C,von Gegerfelt A,Patel V,Zhang GM,Chowdhury B,Broderick KE,Sardesai NY,Valentin A,Rosati M,Felber BK,Pavlakis GN

更新日期：2011-09-09 00:00:00

abstract：:Active surveillance was conducted by the 12 centers of the Canadian Immunization Monitoring Program, Active from 2000-2007 in children 16 years of age and younger to determine the influence of 7-valent pneumococcal conjugate immunization programs on the prevalence, serotype and antibiotic resistance patterns of invasi...

journal_title：Vaccine

authors： Bettinger JA,Scheifele DW,Kellner JD,Halperin SA,Vaudry W,Law B,Tyrrell G,Canadian Immunization Monitoring Program, Active (IMPACT).

更新日期：2010-02-25 00:00:00

abstract：:We have evaluated in C57/Bl6 and HLA-A2.1 transgenic mice the immunogenicity of three MVA vectors expressing either native HCV E1E2 polyprotein, truncated and secreted E1 (E'1(311)) and E2 (E'2(661)) proteins, or a chimeric E1E2 heterodimer presented at the plasma membrane. Immunization induced mainly a Th1 response i...

journal_title：Vaccine

authors： Abraham JD,Himoudi N,Kien F,Berland JL,Codran A,Bartosch B,Baumert T,Paranhos-Baccala G,Schuster C,Inchauspé G,Kieny MP

更新日期：2004-09-28 00:00:00

abstract：:To determine the distribution of rotavirus strains and facilitate vaccine policy decisions in Taiwan, active hospital-based gastroenteritis surveillance was conducted in three sentinel hospitals. From 1 January 2005 to 31 December 2007, a total of 3435 children less than 5 years old with gastroenteritis were enrolled....

journal_title：Vaccine

authors： Wu FT,Liang SY,Tsao KC,Huang CG,Lin CY,Lin JS,Su CY,Eng HL,Yang JY,Chen PJ,Yang CF

更新日期：2009-11-20 00:00:00