Abstract:
:Lipoprotein dynamics are complex during the postprandial state. A significant rise in chylomicron concentration is associated with increased competition for LPL with VLDL particles. This results in an increased concentration of large VLDL. The concentration of small VLDL is reduced as a result of diminished conversion of large to small VLDL. Such changes, induced in the postprandial state, complicate the application and development of models that describe lipoprotein particle kinetics. The development of models that integrate chylomicron and VLDL particle information, rather than surrogate markers, together with data including other variables will provide insight into the complexity of lipoprotein metabolism in the postprandial state.
journal_name
Atherosclerosisjournal_title
Atherosclerosisauthors
Hugh P,Barrett Rdoi
10.1016/s0021-9150(98)00215-9subject
Has Abstractpub_date
1998-12-01 00:00:00pages
S35-40eissn
0021-9150issn
1879-1484pii
S0021-9150(98)00215-9journal_volume
141 Suppl 1pub_type
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