Activation of Th17/Th1 and Th1, but not Th17, is associated with the acute cardiac event in patients with acute coronary syndrome.

abstract：BACKGROUND AND AIMS:Decreased nitric oxide (NO) bioavailability and increased oxidative stress may be involved in the pathogenesis of contrast-induced acute kidney injury (CI-AKI). The relationship between asymmetric dimethylarginine (ADMA), an endogenous NO synthase inhibitor, and CI-AKI is unknown. METHODS:We measur...

journal_title：Atherosclerosis

authors： Lu TM,Hsu CP,Chang CF,Lin CC,Lee TS,Lin SJ,Chan WL

更新日期：2016-11-01 00:00:00

abstract：:The Framingham risk score (FRS), developed in a white cohort aged 30-74 years, is increasingly used in the early risk identification for coronary artery disease (CAD). This study examines the relationship between FRS and carotid artery intima-media thickness (IMT), a surrogate marker of coronary atherosclerosis, in bl...

journal_title：Atherosclerosis

authors： Kieltyka L,Urbina EM,Tang R,Bond MG,Srinivasan SR,Berenson GS

更新日期：2003-09-01 00:00:00

abstract：RATIONALE:Macrophage cholesterol homeostasis maintenance is the result of a balance between influx, endogenous synthesis, esterification/hydrolysis and efflux. Excessive accumulation of cholesterol leads to foam cell formation, which is the major pathology of atherosclerosis. Previous studies have shown that miR-27 (mi...

journal_title：Atherosclerosis

authors： Zhang M,Wu JF,Chen WJ,Tang SL,Mo ZC,Tang YY,Li Y,Wang JL,Liu XY,Peng J,Chen K,He PP,Lv YC,Ouyang XP,Yao F,Tang DP,Cayabyab FS,Zhang DW,Zheng XL,Tian GP,Tang CK

更新日期：2014-05-01 00:00:00

abstract：:This study investigates the ability of a single, low dose of apolipoprotein (apo) A-I, the main lipoprotein of high density lipoproteins (HDL), to inhibit acute vascular inflammation in normocholesterolemic New Zealand White rabbits. Acute vascular inflammation was induced in the animals by placing a non-occlusive, si...

journal_title：Atherosclerosis

authors： Puranik R,Bao S,Nobecourt E,Nicholls SJ,Dusting GJ,Barter PJ,Celermajer DS,Rye KA

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:γ-butyrobetaine (γBB) is a metabolite from dietary Carnitine, involved in the gut microbiota-dependent conversion from Carnitine to the pro-atherogenic metabolite trimethylamine-N-oxide (TMAO). Orally ingested γBB has a pro-atherogenic effect in experimental studies, but γBB has not been studied ...

journal_title：Atherosclerosis

authors： Skagen K,Trøseid M,Ueland T,Holm S,Abbas A,Gregersen I,Kummen M,Bjerkeli V,Reier-Nilsen F,Russell D,Svardal A,Karlsen TH,Aukrust P,Berge RK,Hov JE,Halvorsen B,Skjelland M

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Results of endovascular repair vary according to the arterial bed. We hypothesized that these differences may be related to the plaque features. To explore this hypothesis, we designed a prospective study that compared carotid and femoral atheroma. METHODS AND RESULTS:Patients that underwent femoral or carot...

journal_title：Atherosclerosis

authors： Herisson F,Heymann MF,Chétiveaux M,Charrier C,Battaglia S,Pilet P,Rouillon T,Krempf M,Lemarchand P,Heymann D,Gouëffic Y

更新日期：2011-06-01 00:00:00

abstract：:The St. Thomas mixed hyperlipidaemic (SMHL) rabbit exhibits an inherited hyperlipidaemia similar to that seen in familial combined hyperlipidaemia (FCHL). In this study, we investigated whether the SMHL rabbit is insulin resistant, a condition often associated with FCHL. Six young and six mature combined hyperlipidaem...

journal_title：Atherosclerosis

authors： de Roos B,Caslake MJ,Ardern HA,Martin Benson G,Suckling KE,Packard CJ

更新日期：2001-06-01 00:00:00

abstract：:The emergence of pathophysiological, epidemiologic, and genetic data strongly supports the causality for lipoprotein(a) [Lp(a)] in cardiovascular disease (CVD) and calcific aortic valve disease (CAVD). In parallel, novel Lp(a) lowering approaches have been developed that have re-invigorated clinical interest in Lp(a)....

journal_title：Atherosclerosis

authors： Tsimikas S,Stroes ESG

更新日期：2020-05-01 00:00:00

abstract：:The role of endothelium-derived nitric oxide (NO) in modulation of large artery stiffness in patients with peripheral arterial disease (PAD) is unexplored. The aim of this study was to evaluate, using pulse wave analysis (PWA), changes in aortic and systemic arterial stiffness following administration of nitroglycerin...

journal_title：Atherosclerosis

authors： Kals J,Kampus P,Kals M,Pulges A,Teesalu R,Zilmer M

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:We examined socioeconomic and ethnic differences in use of lipid-lowering drugs after deregulation of simvastatin in the UK for adults with moderate or high risk of coronary heart disease. METHODS:3631 participants in the Whitehall II cohort study (mean age 62.7 years, 91% white) were informed of their risk...

journal_title：Atherosclerosis

authors： Forde I,Chandola T,Raine R,Marmot MG,Kivimaki M

更新日期：2011-03-01 00:00:00

abstract：:Glycoprotein VI is a platelet collagen receptor binding to subendothelial collagen after a rupture of an atherosclerotic plaque. The GPVI gene is polymorphic with several SNPs and the T13254C polymorphism predicting amino acid substitution (serine to proline) has been associated with the risk of MI in a preliminary st...

journal_title：Atherosclerosis

authors： Ollikainen E,Mikkelsson J,Perola M,Penttilä A,Karhunen PJ

更新日期：2004-09-01 00:00:00

abstract：:The effects of lovastatin therapy on concentrations and compositions of lipoproteins were examined in 14 patients with heterozygous familial hypercholesterolemia. The drug lowered plasma levels of cholesterol in total plasma, very low density + intermediate density lipoproteins (VLDL + IDL) and low density lipoprotein...

journal_title：Atherosclerosis

authors： Nozaki S,Vega GL,Haddox RJ,Dolan ET,Grundy SM

更新日期：1990-10-01 00:00:00

abstract：:Inflammation has been demonstrated to be an important risk factor for the development of cardiovascular events. Patients with elevated white blood cell counts have been shown to be in a higher risk of developing acute myocardial infarction and acute coronary and vascular events. We review the clinical data of high whi...

journal_title：Atherosclerosis

authors： Hoffman M,Blum A,Baruch R,Kaplan E,Benjamin M

更新日期：2004-01-01 00:00:00

abstract：:Twelve subjects (6 women, 6 men) were given 120 g fat orally for 2 h to study its effect on serum high density lipoproteins (HDL), HDL subfractions and apoproteins A-I and A-II. In addition, we measured the fasting activity of adipose tissue lipoprotein lipase (LPL). The HDL2 mass concentration increased significantly...

journal_title：Atherosclerosis

authors： Taskinen MR,Kuusi T

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVE:C-reactive protein (CRP) gene variation, in particular an rs2794521 variant was recently associated with type 2 diabetes mellitus (T2DM) in Pima Indians. RESEARCH DESIGN AND METHODS:The present investigation was conducted to replicate this previous association, and to further examine the potential associatio...

journal_title：Atherosclerosis

authors： Zee RY,Germer S,Thomas A,Raji A,Rhees B,Ridker PM,Lindpaintner K,Williams GH,Nathan DM,Martin M

更新日期：2008-04-01 00:00:00

abstract：:Genetic variation in ABCA1 significantly affects HDL levels and atherosclerotic risk. The aim of this study was to examine lifestyle factors influencing ABCA1 expression in human leukocytes and skeletal muscle. A fasting venous blood sample and a vastus lateralis muscle biopsy were taken from 30 volunteers (53+/-1 yea...

journal_title：Atherosclerosis

authors： Hoang A,Tefft C,Duffy SJ,Formosa M,Henstridge DC,Kingwell BA,Sviridov D

更新日期：2008-03-01 00:00:00

abstract：:Familial hypobetalipoproteinemia is an autosomal co-dominant disorder, which in a minority of cases is due to a truncation producing mutation in the apoB gene. We have identified an apoB mutation in a 40-year old hypobetalipoproteinemic man with Type II diabetes mellitus. Immunoblotting of plasma revealed a major band...

journal_title：Atherosclerosis

authors： Pulai JI,Latour MA,Kwok PY,Schonfeld G

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Only a few previous studies have investigated endothelium-dependent vasodilation in the metabolic syndrome (MetS). In the Prospective Study of the Vasculature in Uppsala Seniors (PIVUS) study, different techniques to assess vasodilation in conduit and resistance arteries were evaluated in relation to the Met...

journal_title：Atherosclerosis

authors： Lind L

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Osteoporosis and coronary heart disease (CHD) are very common conditions among elderly people, and both represent a public health concern due to their prognostic consequences. Osteoporosis and CHD share many risk factors and pathophysiological mechanisms, such as calcification pathways. Clinical evi...

journal_title：Atherosclerosis

authors： Campos-Staffico AM,Freitas WM,Carvalho LSF,Coelho-Filho OR,Nadruz W Jr,Oliveira RB,Sposito AC,Brasilia Study on Healthy Aging and Brasilia Heart Study.

更新日期：2020-01-01 00:00:00

abstract：:Lack of physical activity appears to have deleterious effects on serum lipoproteins. Twenty-three patients who were completely immobilised by traumatic fracture of the spine had significantly lower (P < 0.001) plasma high density lipoprotein cholesterol (HDL-C) and apolipoprotein A-I levels than normally mobile paired...

journal_title：Atherosclerosis

authors： Nikkilä EA,Kuusi T,Myllynen P

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Individuals with type 1 diabetes mellitus are at high risk of developing atherosclerotic cardiovascular disease, but the underlying mechanisms by which type 1 diabetes accelerates atherosclerosis remain unknown. Increased retention of low-density lipoprotein (LDL) in atherosclerosis-prone sites of t...

journal_title：Atherosclerosis

authors： Hagensen MK,Mortensen MB,Kjolby M,Stillits NL,Steffensen LB,Bentzon JF

更新日期：2017-08-01 00:00:00

abstract：:Various oils have been used as vehicles for cholesterol in diets used to produce atherosclerosis in rabbits. Because such oils may affect the physico-chemical properties of the beta-VLDL produced in response to cholesterol feeding, we have studied the physico-chemical characteristics of beta-VLDL isolated from cholest...

journal_title：Atherosclerosis

authors： Waugh DA,Tercyak AM,Small DM

更新日期：1989-04-01 00:00:00

abstract：:Simvastatin, an inhibitor of HMG CoA reductase, lowers the plasma total cholesterol and LDL-cholesterol concentration in familial hypercholesterolemic patients. The efficacy of the drug shows considerable inter-individual variation, however. In this study we have assessed the influence of certain LDL-receptor gene mut...

journal_title：Atherosclerosis

authors： Jeenah M,September W,Graadt van Roggen F,de Villiers W,Seftel H,Marais D

更新日期：1993-01-04 00:00:00

abstract：:The relations between triglyceride-rich lipoproteins, alimentary lipaemia and coronary heart disease (CHD) have remained obscure and much debated. We studied the basal and postprandial plasma levels of chylomicron remnants and very low density lipoproteins (VLDL) of varying particle size in 32 male postinfarction pati...

journal_title：Atherosclerosis

authors： Karpe F,Steiner G,Uffelman K,Olivecrona T,Hamsten A

更新日期：1994-03-01 00:00:00

abstract：UNLABELLED:Inflammation plays an important role in atherosclerosis and the genesis of acute coronary syndromes, i.e., atheromatous plaque disruption. Neutrophil count and C-reactive protein (CRP) levels are markers of ongoing inflammation and predictors of cardiovascular risk. We sought to assess whether these inflamma...

journal_title：Atherosclerosis

authors： Avanzas P,Arroyo-Espliguero R,Cosín-Sales J,Quiles J,Zouridakis E,Kaski JC

更新日期：2004-07-01 00:00:00

abstract：:Over 200 risk factors for cardiovascular disease (CVD) have now been identified. Among these, the three most important are (1) abnormal lipids, including the fact that there are more than 15 types of cholesterol-containing lipoproteins and four different types of triglyceride-rich particles, some of which are very ath...

journal_title：Atherosclerosis

authors： Castelli WP

更新日期：1996-07-01 00:00:00

abstract：INTRODUCTION:The possible cause of accelerated atherosclerosis in NAFLD may be the relationship with the MetS and its components. Our primary goal was to evaluate the relationship between NAFLD and subclinical atherosclerosis in adult male patients between 20 and 40 years of age. Moreover, we aimed to investigate the c...

journal_title：Atherosclerosis

authors： Ozturk K,Uygun A,Guler AK,Demirci H,Ozdemir C,Cakir M,Sakin YS,Turker T,Sari S,Demirbas S,Karslıoğlu Y,Saglam M

更新日期：2015-06-01 00:00:00

abstract：:Mevinolin (MK-803) is a potent inhibitor of HMG-CoA reductase. After a placebo run-in period, mevinolin 5,15 or 50 mg, or placebo was given twice daily for 7-11 days under double -blind conditions ot 4 groups of 6 normocholesterolemic male volunteers. After 7 days, mean serum cholesterol fell 14%, 25% and 24% on 5, 15...

journal_title：Atherosclerosis

authors： Tobert JA,Hitzenberger G,Kukovetz WR,Holmes IB,Jones KH

更新日期：1982-01-01 00:00:00

abstract：:We studied the functional role of N-linked sugar chains of apolipoprotein (apo) B-100 of low density lipoprotein (LDL) in cholesterol metabolism. The N-linked sugar chains of apo B-100 of LDL obtained from four homozygous Watanabe heritable hyperlipidemic (WHHL) rabbits were liberated by hydrazinolysis, followed by Na...

journal_title：Atherosclerosis

authors： Fujioka Y,Taniguchi T,Ishikawa Y,Shiomi M,Yokoyama M

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The TNF-superfamily member sTWEAK and its scavenger receptor sCD163 are potentially involved in pathophysiological processes of atherosclerosis. In patients with peripheral arterial disease, previous research has shown that sTWEAK and the sCD163/sTWEAK ratio were independently associated with long t...

journal_title：Atherosclerosis

authors： Mrak D,Zierfuss B,Höbaus C,Herz CT,Pesau G,Schernthaner GH

更新日期：2021-01-01 00:00:00