Leukocytes and coronary heart disease.

abstract：BACKGROUND AND AIMS:High concentrations of low density lipoprotein (LDL) triglycerides have been associated with prevalent angiographic coronary artery disease. The present analysis was designed to investigate the association of LDL triglycerides with cardiovascular mortality and to explore possible mechanisms that may...

journal_title：Atherosclerosis

authors： Silbernagel G,Scharnagl H,Kleber ME,Delgado G,Stojakovic T,Laaksonen R,Erdmann J,Rankinen T,Bouchard C,Landmesser U,Schunkert H,März W,Grammer TB

更新日期：2019-03-01 00:00:00

abstract：:Extensive research has been carried out in recent years to discover the potential risk factors contributing to cardiac allograft atherogenesis. Injury to endothelial cells has been regarded as an important early mechanism in the development of transplant atherosclerosis; it leads to the manifestation of epicardial and...

journal_title：Atherosclerosis

authors： Liu Z,Wildhirt SM,Weismüller S,Schulze C,Conrad N,Reichart B

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Soluble urokinase plasminogen activator receptor (suPAR) is an inflammatory marker associated with cardiovascular disease. Statins lower both low-density lipoprotein (LDL)-cholesterol and C-reactive protein (CRP), resulting in improved outcomes. However, whether lipid-lowering therapy also lowers su...

journal_title：Atherosclerosis

authors： Hodges GW,Bang CN,Forman JL,Olsen MH,Boman K,Ray S,Kesäniemi YA,Eugen-Olsen J,Greve AM,Jeppesen JL,Wachtell K

更新日期：2018-05-01 00:00:00

abstract：:To test the hypothesis of altered energy production in aortic sites predisposed to lesion formation, both coupled oxidative phosphorylation (evaluated from P/O ratios) and control of the energy-linked (ATP) NADH transhydrogenase were examined in muscular cushions at the celiac artery bifurcation. Comparisons were made...

journal_title：Atherosclerosis

authors： Hajjar DP,Smith SC

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:A hallmark feature of atherosclerosis is inflammation mediated by prostaglandins (PGs) catalyzed by the enzyme cyclooxygenase (COX). The present study explored whether the COX-2 G-765C polymorphism contributes to increased incidence of coronary heart disease (CHD) or stroke in the large prospective Atheroscl...

journal_title：Atherosclerosis

authors： Kohsaka S,Volcik KA,Folsom AR,Wu KK,Ballantyne CM,Willerson JT,Boerwinkle E

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:To analyze the possible role of arachidonic acid (AA) in macrophage cholesterol biosynthesis and in PON2 expression. METHODS AND RESULTS:We used peritoneal macrophages (MPM) from the 6-DS KO mice that were fed a diet without or with AA. Macrophage cholesterol biosynthesis rate and HMGCoA-reductase mRNA level...

journal_title：Atherosclerosis

authors： Rosenblat M,Volkova N,Roqueta-Rivera M,Nakamura MT,Aviram M

更新日期：2010-06-01 00:00:00

abstract：:Atherosclerotic calcification may weaken the aorta wall and thereby lead to rupture of the vessel. The mechanism whereby aortas undergo calcification remains unclear. Previous reports in this laboratory showed that, after 2 months of cholesterol-supplemental feeding, an increase in calcifiability of membrane vesicles ...

journal_title：Atherosclerosis

authors： Hsu HH,Camacho NC,Tawfik O,Sun F

更新日期：2002-03-01 00:00:00

abstract：:Two groups of patients were administered either 4.5 X 10(6) U or 90 X 10(6) U each of recombinant DNA-derived interferon-beta serine (IFN-beta ser) i.v. daily for 10 days. IFN-beta ser affected lipoprotein lipids of patients in a dose dependent fashion. A decrease in plasma total cholesterol concentration occurred 24 ...

journal_title：Atherosclerosis

authors： Rosenzweig IB,Wiebe DA,Borden EC,Storer B,Shrago ES

更新日期：1987-10-01 00:00:00

abstract：:We examined cross-sectional associations between sex hormones and carotid artery intimal-medial thickness (cIMT) and coronary artery calcium in women in the Multi-Ethnic Study of Atherosclerosis. Serum testosterone, estradiol, sex hormone binding globulin (SHBG), and dehydroepiandrosterone levels were measured in 1947...

journal_title：Atherosclerosis

authors： Ouyang P,Vaidya D,Dobs A,Golden SH,Szklo M,Heckbert SR,Kopp P,Gapstur SM

更新日期：2009-05-01 00:00:00

abstract：:Previous studies demonstrated that induction of diabetes with streptozotocin (stz) accelerated atherosclerosis in hyperlipidemic apo E null (-/-) mice. Blockade of the Receptor for Advanced Glycation Endproducts (RAGE) in those animals suppressed acceleration of atherosclerotic lesion area, in a manner independent of ...

journal_title：Atherosclerosis

authors： Wendt T,Harja E,Bucciarelli L,Qu W,Lu Y,Rong LL,Jenkins DG,Stein G,Schmidt AM,Yan SF

更新日期：2006-03-01 00:00:00

abstract：:To investigate the growth-regulating action of estrogen on vascular smooth muscle cells (SMC), effects of beta-17-estradiol (beta-E2) on phenotypic modulation and proliferation of rabbit aortic SMC were observed in vitro. At 10(-8)M, beta-E2 significantly slowed the decrease in volume fraction of myofilaments (Vv myo)...

journal_title：Atherosclerosis

authors： Song J,Wan Y,Rolfe BE,Campbell JH,Campbell GR

更新日期：1998-09-01 00:00:00

abstract：:The well established 'systemic' risk factors for atherosclerosis can explain only half of the variability in its occurrence. To account for some of the remaining variability, it was suggested that certain geometric features of atherosclerosis-prone segments ('geometric risk factors') can increase the likelihood of dis...

journal_title：Atherosclerosis

authors： Friedman MH,Baker PB,Ding Z,Kuban BD

更新日期：1996-09-06 00:00:00

abstract：:We have used discoidal reconstituted high density lipoproteins (rHDL) containing apolipoprotein (apo) A-I and dimyristoyl phosphatidylcholine (DMPC) as a tool to investigate the time sequence of the HDL-mediated inhibition of vascular cell adhesion molecule (VCAM)-1 and E-selectin expression in cytokine-activated huma...

journal_title：Atherosclerosis

authors： Clay MA,Pyle DH,Rye KA,Vadas MA,Gamble JR,Barter PJ

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:the extracellular matrix (ECM) is an important determinant of plaque instability. Since tissue transglutaminase (tTG) and elafin act as stabilizing factors, they might play a crucial role in the pathogenesis of acute coronary syndrome. We examined their expression in human coronary arteries and the regulatio...

journal_title：Atherosclerosis

authors： Sumi Y,Inoue N,Azumi H,Seno T,Okuda M,Hirata K,Kawashima S,Hayashi Y,Itoh H,Yokoyama M

更新日期：2002-01-01 00:00:00

abstract：:Thrombomodulin, an endothelial membrane glycoprotein, is an essential part of the protein C anti-coagulant pathway. It may also have a role in the regulation of fibrinolysis. We carried out a cross-sectional study to assess the association of soluble thrombomodulin (sTM) with peripheral artery disease (PAD) in a strat...

journal_title：Atherosclerosis

authors： Salomaa V,Matei C,Aleksic N,Sansores-Garcia L,Folsom AR,Juneja H,Park E,Wu KK

更新日期：2001-08-01 00:00:00

abstract：:Recent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD) among urban black South Africans. The aim was to track the progression of CVD risk factors in a multi-ethnic sample of South Africans. Participants were 173 black (aged 47.5 ± 7.8 yrs) and 186 white teachers (aged 49.6...

journal_title：Atherosclerosis

authors： Hamer M,von Känel R,Reimann M,Malan NT,Schutte AE,Huisman HW,Malan L

更新日期：2015-01-01 00:00:00

abstract：:Essential polyunsaturated fatty acids (PUFA) of the omega-3 family are believed to protect against cardiovascular disease. A rich source of omega-3 PUFA is found in fish and marine mammals (seal, walrus, whale), which are a large part of the traditional diet of Alaska Natives (Eskimo, American Indians, Aleuts), a grou...

journal_title：Atherosclerosis

authors： McLaughlin J,Middaugh J,Boudreau D,Malcom G,Parry S,Tracy R,Newman W

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVES:To analyze the relationship between office and ambulatory heart rate, and its variability, and arterial stiffness in patients with primary arterial hypertension. METHODS:A cross-sectional study was conducted in a primary care setting, with the inclusion of 356 hypertensive patients aged 30-80 years. Office ...

journal_title：Atherosclerosis

authors： García-Ortiz L,García-García A,Ramos-Delgado E,Patino-Alonso MC,Recio-Rodríguez JI,Rodríguez-Sánchez E,Gómez-Marcos MA

更新日期：2011-08-01 00:00:00

abstract：:The dose-response effects of clofibrate and niceritrol on serum cholesterol and triglycerides (TG) were studied in 29 patients with Type IIa and IIb hyperlipoproteinaemia. In 17 patients, clofibrate and niceritrol were then given as combined treatment, and the effects of this combination on serum lipoproteins were stu...

journal_title：Atherosclerosis

authors： Olsson AG,Orö L,Rössner S

更新日期：1975-07-01 00:00:00

abstract：BACKGROUND:Calcific aortic valve disease is an active and progressive condition. Data indicate that aortic valve calcification (AVC) is associated with endothelial dysfunction and accepted as a manifestation of atherosclerosis. Coronary flow reserve (CFR) determined by transthoracic echocardiography has been introduced...

journal_title：Atherosclerosis

authors： Bozbas H,Pirat B,Yildirir A,Simşek V,Sade E,Eroglu S,Atar I,Altin C,Demirtas S,Ozin B,Muderrisoglu H

更新日期：2008-04-01 00:00:00

abstract：:The intravascular metabolism of cholesteryl [1-14C]oleoyl ester and [1,2-3H(N)]cholesteryl palmityl ether was compared in the rat, an animal species without plasma cholesteryl ester transfer activity (CETA). The tracers had identical plasma disappearance rates when they were incorporated into human or rat low density ...

journal_title：Atherosclerosis

authors： Terpstra AH

更新日期：1995-01-06 00:00:00

abstract：:The association between cardiorespiratory fitness (VO2max) and carotid atherosclerosis was analyzed in 163 men, aged 50 to 60 years. VO2max was assessed using breath-by-breath respiratory gas analyses during maximal exercise stress test. Atherosclerosis was evaluated quantitatively as intima-media thickness (IMT) of t...

journal_title：Atherosclerosis

authors： Rauramaa R,Rankinen T,Tuomainen P,Väisänen S,Mercuri M

更新日期：1995-01-20 00:00:00

abstract：:The haptoglobin genotype has been demonstrated to be an independent risk factor for CVD in multiple epidemiological studies. The primary function of haptoglobin is to mitigate the deleterious effects of extracorpuscular hemoglobin. We sought to determine if the protein products of the two haptoglobin alleles differed ...

journal_title：Atherosclerosis

authors： Guetta J,Strauss M,Levy NS,Fahoum L,Levy AP

更新日期：2007-03-01 00:00:00

abstract：:The differences in the fatty acid spectra of serum samples obtained from vegetarians (62 females, 40 males) and non-vegetarians (70 females, 38 males) were evaluated in a matched-pair study design. This study population made it possible to examine 48 female and 31 male pairs whose age difference did not exceed 3 years...

journal_title：Atherosclerosis

authors： Melchert HU,Limsathayourat N,Mihajlović H,Eichberg J,Thefeld W,Rottka H

更新日期：1987-05-01 00:00:00

abstract：:Randomized lard and butter oil were conpared with native lard and butter oil for their effects on cholesterol-induced atherosclerosis in rabbits. In each experiment there was also a group fed corn oil. The diets contained 2% cholesterol and 6% fat and were fed for eight weeks. Randomization of either butter or lard ha...

journal_title：Atherosclerosis

authors： Kritchevsky D,Tepper SA

更新日期：1977-07-01 00:00:00

abstract：:The present study is the first work to evaluate thrombin-, ADP-, and collagen-induced platelet aggregation in laboratory rats receiving alimentation with the parenterally-administered lipid emulsion, Lipofundin-S, in doses sufficient to induce early atherosclerotic changes in the aorta. The aggregometry parameters of ...

journal_title：Atherosclerosis

authors： Saladino CF,Fox RL,Yeh Q,Karpowicz F,Feffer SE,Jonas EA

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Lipoprotein distribution of non-cholesterol sterols was studied to evaluate in which lipoproteins they are carried in type 2 diabetes with body weight ranging from normal to overweight. METHODS:Serum and lipoprotein squalene and non-cholesterol sterols were quantitated with gas-liquid chromatography in 33 d...

journal_title：Atherosclerosis

authors： Simonen PP,Gylling H,Miettinen TA

更新日期：2007-09-01 00:00:00

abstract：:Platelet phospholipid composition was analyzed before and after extracorporeal removal of low density lipoproteins (LDL) by LDL apheresis in six patients with familial hypercholesterolemia. Elevated levels of total plasma cholesterol and the portion of plasma cholesterol carried by LDL were reduced by 56 and 66% after...

journal_title：Atherosclerosis

authors： Bräutigam R,Bräutigam C,Lorenz R,Richter WO,Engelmann B

更新日期：1997-05-01 00:00:00

abstract：:Large (Sf greater than 100) and small (Sf 100-20) very low density lipoprotein (VLDL) particles were isolated by density gradient ultracentrifugation and characterized chemically in 8 patients with primary hypertriglyceridemia before and after 6 weeks treatment with 4 grammes daily of nicotinic acid (NA). Concomitant ...

journal_title：Atherosclerosis

authors： Tornvall P,Hamsten A,Johansson J,Carlson LA

更新日期：1990-10-01 00:00:00

abstract：:Blood pressure elevation is frequently associated with elevated cholesterol, triglyceride or low density lipoprotein (LDL-C) or low high density lipoprotein (HDL-C). The relative importance of genetic and environmental factors in these associations is unclear. We examined the relative contribution of genetic and envir...

journal_title：Atherosclerosis

authors： Williams PD,Puddey IB,Martin NG,Beilin LJ

更新日期：1993-04-01 00:00:00