Cross-sectional association of soluble thrombomodulin with mild peripheral artery disease; the ARIC study. Atherosclerosis Risk in Communities.

abstract：:Arteriolar wall thickness was measured in cigarette smokers by means of eyepiece micrometry, paper planimetry and computerized planimetry. Myocardial and renal arterioles in such smokers showed significant thickening of their walls. This thickening was mainly attributable to an increase in collagen and smooth muscle. ...

journal_title：Atherosclerosis

authors： Oberai B,Adams CW,High OB

更新日期：1984-08-01 00:00:00

abstract：:The effect of administration of probucol in preventing intimal thickening of rabbit carotid artery after balloon catheter injury and the mechanism of action of the drug were studied. Groups of 6 male New Zealand-White rabbits were given normal diet (Group I), high cholesterol diet (Group II) or high cholesterol diet p...

journal_title：Atherosclerosis

authors： Shinomiya M,Shirai K,Saito Y,Yoshida S

更新日期：1992-12-01 00:00:00

abstract：:Cardiovascular risk is increased in patients with diabetic nephropathy. The aim of this study was to examine the relative impacts of albuminuria and renal failure, the two important features of diabetic nephropathy, on potentially atherogenic lipoprotein changes in this condition. The subjects were 160 non-diabetic he...

journal_title：Atherosclerosis

authors： Shoji T,Emoto M,Kawagishi T,Kimoto E,Yamada A,Tabata T,Ishimura E,Inaba M,Okuno Y,Nishizawa Y

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:In chronic kidney disease (CKD), high FGF23 concentrations are associated with left ventricular hypertrophy (LVH), cardiovascular events, and death. The associations of FGF23 with left ventricular mass (LVM) and LVH in the general population and the influence of CKD remains uncertain. METHODS:C-terminal pla...

journal_title：Atherosclerosis

authors： Jovanovich A,Ix JH,Gottdiener J,McFann K,Katz R,Kestenbaum B,de Boer IH,Sarnak M,Shlipak MG,Mukamal KJ,Siscovick D,Chonchol M

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Cathepsin L (CatL), cathepsin K (CatK), and cathepsin V (CatV) are potent elastases implicated in human arterial wall remodeling. Whether plasma levels of these cathepsins are altered in patients with abdominal aortic aneurysms (AAAs) remains unknown. METHODS AND RESULTS:Plasma samples were collected from 4...

journal_title：Atherosclerosis

authors： Lv BJ,Lindholt JS,Wang J,Cheng X,Shi GP

更新日期：2013-09-01 00:00:00

abstract：:In order to obtain information about the developmental mechanisms of restenosis after angioplasty, we investigated an association between the expression of platelet-derived growth factors (PDGFs) and neointimal cell accumulation in rabbit femoral arteries subjected to balloon angioplasty. Northern analysis demonstrate...

journal_title：Atherosclerosis

authors： Uchida K,Sasahara M,Morigami N,Hazama F,Kinoshita M

更新日期：1996-07-01 00:00:00

abstract：:A recent study has suggested that symptoms of chronic bronchitis predict the risk of coronary disease independently of the known major cardiovascular risk factors. High serum levels of lipoprotein(a) (Lp(a)) have also been considered as an independent risk factor for coronary heart disease. Therefore, the aim of the p...

journal_title：Atherosclerosis

authors： Basili S,Ferroni P,Vieri M,Cardelli P,Ceci F,Paradiso M,Labbadia G,Gazzaniga PP,Cordova C,Alessandri C

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:Previous investigations have revealed an association between the ABO locus/blood group and total cholesterol and inflammatory biomarker levels. We aimed to test the statistical association of ABO locus variants with lipid profiles and levels of thirteen inflammatory markers in a Taiwanese population. METHODS...

journal_title：Atherosclerosis

authors： Teng MS,Hsu LA,Wu S,Chou HH,Chang CJ,Sun YZ,Juan SH,Ko YL

更新日期：2013-06-01 00:00:00

abstract：:Previous studies in mouse models showed that 12/15lipoxygenase (12/15LO) gene disruption diminishes atherosclerosis. Pharmacologic suppression of thromboxane (Tx) A(2) biosynthesis or blockade of its receptor also reduces the development of the disease in the same models. We tested the hypothesis that simultaneous gen...

journal_title：Atherosclerosis

authors： Tang L,Ding T,Praticò D

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Atherosclerosis is characterized by lipid accumulation and chronic inflammation in the arterial wall. Elevated levels of apolipoprotein (apo) B-containing lipoproteins are a risk factor for cardiovascular disease (CVD). By contrast, plasma levels of functional high-density lipoprotein (HDL) and apoA-I are pr...

journal_title：Atherosclerosis

authors： Hennuyer N,Duplan I,Paquet C,Vanhoutte J,Woitrain E,Touche V,Colin S,Vallez E,Lestavel S,Lefebvre P,Staels B

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Previous studies have found polymorphisms of the HDL receptor, SR-BI, to be associated with plasma HDL-C in women, but not men, suggesting a modifying role of estrogen. We examined whether the association between SR-BI genotypes and HDL-C is modified by use of unopposed estrogen in community-dwelling postmen...

journal_title：Atherosclerosis

authors： Richard E,von Muhlen D,Barrett-Connor E,Alcaraz J,Davis R,McCarthy JJ

更新日期：2005-06-01 00:00:00

abstract：:Copper mediated oxidative modification of high density lipoprotein (HDL) diminishes its capacity to promote cholesterol efflux from cells in culture. In the present study, HDL was isolated from eight subjects before and after a 10 day administration of the antioxidant vitamins C and E. After incubation HDL (1.25 mg pr...

journal_title：Atherosclerosis

authors： Rifici VA,Khachadurian AK

更新日期：1996-11-15 00:00:00

abstract：:It has been reported that total cholesterol (Chol) response to probucol is greater in familial hypercholesterolemic (FH) patients with apo E4 than in those without apo E4. We further examined the effect of probucol on plasma triglyceride (TG) and lipoprotein-Chol levels as well as total Chol levels in heterozygous FH ...

journal_title：Atherosclerosis

authors： Eto M,Sato T,Watanabe K,Iwashima Y,Makino I

更新日期：1990-09-01 00:00:00

abstract：:We describe the cardiovascular state of a 60-year-old homozygous patient with familial HDL deficiency (Tangier disease). The patient was examined by coronary angiography and intravascular ultrasound because of chest pain at rest and on exertion. We found a normal left ventricular function, moderately diffuse coronary ...

journal_title：Atherosclerosis

authors： Walter M,Kerber S,Fechtrup C,Seedorf U,Breithardt G,Assmann G

更新日期：1994-10-01 00:00:00

abstract：:Essential polyunsaturated fatty acids (PUFA) of the omega-3 family are believed to protect against cardiovascular disease. A rich source of omega-3 PUFA is found in fish and marine mammals (seal, walrus, whale), which are a large part of the traditional diet of Alaska Natives (Eskimo, American Indians, Aleuts), a grou...

journal_title：Atherosclerosis

authors： McLaughlin J,Middaugh J,Boudreau D,Malcom G,Parry S,Tracy R,Newman W

更新日期：2005-08-01 00:00:00

abstract：:The effect of chlorthalidone treatment on serum lipids and lipoproteins was investigated in 21 hypertensive patients. Chlorthalidone caused an increase in total serum and low density lipoprotein (LDL) cholesterol, but not in high density lipoprotein (HDL) cholesterol. Serum and lipoprotein triglycerides also increased...

journal_title：Atherosclerosis

authors： Rosenthal T,Holtzman E,Segal P

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:Lipoprotein distribution of non-cholesterol sterols was studied to evaluate in which lipoproteins they are carried in type 2 diabetes with body weight ranging from normal to overweight. METHODS:Serum and lipoprotein squalene and non-cholesterol sterols were quantitated with gas-liquid chromatography in 33 d...

journal_title：Atherosclerosis

authors： Simonen PP,Gylling H,Miettinen TA

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Increased arterial stiffness is associated with greater risk of cardiovascular events and mortality. However, in patients with peripheral arterial disease (PAD) who have severe atherosclerotic disorder or risk clustering, the major determinants of increased stiffness have been not clarified. METHODS:This st...

journal_title：Atherosclerosis

authors： Makita S,Matsui H,Naganuma Y,Abiko A,Tamada M,Nakamura M

更新日期：2010-01-01 00:00:00

abstract：:Oxidized low-density lipoproteins (LDL) impair endothelium-dependent dilation and constrict arteries. This study examined possible relation of the circulating plasma levels of Ox-LDL to coronary spastic angina (CSA). The plasma levels of Ox-LDL were measured by ELISA in 37 consecutive patients with CSA and normal coro...

journal_title：Atherosclerosis

authors： Kugiyama K,Sugiyama S,Soejima H,Kawano H,Sakamoto T,Takazoe K,Ogawa H,Doi H,Yasue H

更新日期：2001-02-01 00:00:00

abstract：:Blood pressure elevation is frequently associated with elevated cholesterol, triglyceride or low density lipoprotein (LDL-C) or low high density lipoprotein (HDL-C). The relative importance of genetic and environmental factors in these associations is unclear. We examined the relative contribution of genetic and envir...

journal_title：Atherosclerosis

authors： Williams PD,Puddey IB,Martin NG,Beilin LJ

更新日期：1993-04-01 00:00:00

abstract：:Estrogen use is associated with protection from cardiovascular disease in postmenopausal women. This benefit appears to be magnified among women with pre-existing heart disease. The possible bias of intrinsically better health in women using estrogen has not been ruled out in observational studies. Therefore, two doub...

journal_title：Atherosclerosis

authors： Knopp RH,Zhu X,Bonet B

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:We investigated whether statin-treated heterozygous familial hypercholesterolemic (FH) patients have lower plasma coenzyme Q(10) (CoQ(10)) levels than low-density lipoprotein receptor (LDLR) mutation negative FH patients on equivalent statin doses, and whether lower CoQ(10) concentrations are associated with ...

journal_title：Atherosclerosis

authors： Young JM,Molyneux SL,Reinheimer AM,Florkowski CM,Frampton CM,Scott RS,George PM

更新日期：2011-09-01 00:00:00

abstract：:Atherosclerotic plaque-like lesions are prevalent in synthetic arteriovenous shunts created to provide vascular access for hemodialysis. Similarities to atherosclerotic plaques in native arteries include eccentric location, immunoreactivity for smooth muscle actin, dystrophic calcifications, superimposed thrombi, and ...

journal_title：Atherosclerosis

authors： Sloop GD,Fallon KB,Zieske AW

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:It is indicated that total/HDL cholesterol and LDL/HDL cholesterol ratios have more predictive power for cardiovascular disease compared to classic lipid parameters. However, there have been few reports about the usefulness of these indices for the assessment of early stage atherosclerosis in Japanese type 2 ...

journal_title：Atherosclerosis

authors： Katakami N,Kaneto H,Osonoi T,Saitou M,Takahara M,Sakamoto F,Yamamoto K,Yasuda T,Matsuoka TA,Matsuhisa M,Yamasaki Y,Shimomura I

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To compare the prevalence of lower extremity peripheral artery disease (PAD) and to assess whether age-associated progression in ankle-brachial index (ABI) differs between individuals with chronic immune-mediated inflammatory diseases (CIID) and the general population. METHODS:Pooled analysis with data from ...

journal_title：Atherosclerosis

authors： Agüero F,González-Zobl G,Baena-Díez JM,Dégano IR,Garcia-Gil M,Alzamora MT,Marrugat J,Comas-Cufí M,Pera G,Elosua R,Ramos R,Grau M

更新日期：2015-09-01 00:00:00

abstract：:This paper reports the results of the largest autopsy-based comparative study of atherosclerotic lesions between young Japanese and Americans, aged 15-34 years and autopsied between 1987 and 1995, by analyzing the data from the Japanese second nation-wide study of atherosclerosis and Pathobiological Determinants of At...

journal_title：Atherosclerosis

authors： Takei H,Strong JP,Yutani C,Malcom GT

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of this study was to investigate the impact of attenuated-signal plaque (ASP) observed by intravascular ultrasound (IVUS) on vessel response after drug-eluting stent implantation. METHODS:Data were derived from the IVUS cohort of the J-DESsERT trial comparing paclitaxel- and sirolimus-eluti...

journal_title：Atherosclerosis

authors： Kitahara H,Waseda K,Sakamoto K,Yamada R,Huang CC,Nakatani D,Sakata K,Kawarada O,Yock PG,Matsuyama Y,Yokoi H,Nakamura M,Muramatsu T,Nanto S,Fitzgerald PJ,Honda Y

更新日期：2017-04-01 00:00:00

abstract：:We have analyzed the development of aortic and coronary atherosclerosis over 40 years in native and non-native males of Yakutsk by comparing the data obtained in 1963-1965, 1985-1987 and 2001-2003. The research was carried out in compliance with the WHO program for the atherosclerosis epidemiology studies using autops...

journal_title：Atherosclerosis

authors： Zhdanov VS,Sternby NH,Voronova OV,Galakhov IE,Argunov VA

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:DJ-1-a multifunctional protein responding to oxidative stress-is a possible regulator of the inflammatory response that plays an important role in atherosclerosis. Stromal cell-derived factor (SDF)-1 and its receptor, chemokine receptor type 4 (CXCR4), have been implicated in the recruitment of inflammatory c...

journal_title：Atherosclerosis

authors： Jung SH,Won KJ,Lee KP,Lee DH,Yu S,Lee DY,Seo EH,Kang H,Park ES,Kim HJ,Lee SH,Kim B

更新日期：2014-08-01 00:00:00

abstract：:When smoke from single cigarettes containing [4-14C]cholesterol or beta-[4-14C]sitosterol was delivered to the lungs of Rhesus macaques, plasma contained radiolabeled sterols up to 50 days later. Since cholesterol, as well as plant sterols (campesterol, stigmasterol and beta-sitosterol), are normally present in cigare...

journal_title：Atherosclerosis

authors： Malinow MR,McLaughlin P,Aigner-Held R,Upson B,Isabelle LM,Connor WE,Lin D

更新日期：1986-04-01 00:00:00