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Myocardial and renal arteriolar thickening in cigarette smokers.

Abstract：

:Arteriolar wall thickness was measured in cigarette smokers by means of eyepiece micrometry, paper planimetry and computerized planimetry. Myocardial and renal arterioles in such smokers showed significant thickening of their walls. This thickening was mainly attributable to an increase in collagen and smooth muscle. The adventitia of small to medium-sized intramyocardial coronary arteries showed an increase in collagen. Platelets are known to be more adhesive to the vessel wall in smokers. It is suggested that platelet-derived growth factor, released in the vessel wall, may promote proliferation of connective tissues, thus leading to the vascular thickening described.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Oberai B,Adams CW,High OB

doi

10.1016/0021-9150(84)90116-3

subject

Has Abstract

pub_date

1984-08-01 00:00:00

pages

185-90

issue

2

eissn

0021-9150

issn

1879-1484

pii

0021-9150(84)90116-3

journal_volume

52

pub_type

杂志文章

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