Clinical implications of white-coat effect among patients attending at a lipid clinic.

abstract：:The role of endothelial cells (EC) in the development and progression of early swine intimal cell mass (ICM)-derived coronary artery lesions in 55 swine fed either a mash or hyperlipidemic diet for 14, 49 or 90 days was investigated. Characteristics studied were endothelial cell turnover (using tritiated thymidine aut...

journal_title：Atherosclerosis

authors： Scott RF,Kim DN,Schmee J,Thomas WA

更新日期：1986-10-01 00:00:00

abstract：:Low density lipoproteins (LDL) isolated by ultracentrifugation induce cytotoxic changes in cultured human endothelial cells (EC) and fibroblasts if the ratio between LDL cholesterol and the final protein concentration of the culture medium exceeds 0.10-0.12 mmol/g protein. In order to investigate if reactive oxygen sp...

journal_title：Atherosclerosis

authors： Evensen SA,Galdal KS,Nilsen E

更新日期：1983-10-01 00:00:00

abstract：:This report concerns a heart transplant patient with hypercholesterolemia who showed rapid development of a severe transplant coronary artery disease. The patient received 10 mg pravastatine per day. Quantitative coronary angiography analyses of 4 serial angiograms clearly demonstrated that in the first 2.5 years foll...

journal_title：Atherosclerosis

authors： Park JW,Vermeltfoort M,Braun P,May E,Merz M

更新日期：1995-05-01 00:00:00

abstract：:Intact platelets from atherosclerotic rabbits release more thromboxane B2 (TXB2) and 12-hydroxyeicosatetraenoic acid (HETE) than platelets from normal rabbits following incubation with [14C]arachidonic acid (AA). In contrast, no difference is found between homogenates of platelets from normal and atherosclerotic anima...

journal_title：Atherosclerosis

authors： Dembińska-Kièć A,Rücker W,Schönhöfer PS

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Bisphenol A (BPA) levels have previously been associated with coronary heart disease (CHD). Since CHD is an atherosclerotic disease, we investigated if circulating levels of BPA and phthalate metabolites are related to atherosclerosis in a cross-sectional study. METHODS:In the population-based...

journal_title：Atherosclerosis

authors： Lind PM,Lind L

更新日期：2011-09-01 00:00:00

abstract：:Advanced glycation end-products (AGEs), a group of carbohydrate-derived compounds formed by non-enzymatic glycation and oxidation, are markedly elevated in end-stage renal disease (ESRD) and may be related to both inflammation and oxidative stress. The cellular effects of AGE are largely mediated by their interaction ...

journal_title：Atherosclerosis

authors： Rodríguez-Ayala E,Anderstam B,Suliman ME,Seeberger A,Heimbürger O,Lindholm B,Stenvinkel P

更新日期：2005-06-01 00:00:00

abstract：:The metabolism of homocysteine requires contributions of several enzymes and vitamin cofactors. Earlier studies identified a common polymorphism of methylenetetrahydrofolate reductase that was associated with mild hyperhomocysteinemia. Common variants of two other enzymes involved in homocysteine metabolism, methionin...

journal_title：Atherosclerosis

authors： Jacques PF,Bostom AG,Selhub J,Rich S,Ellison RC,Eckfeldt JH,Gravel RA,Rozen R,National Heart, Lung and Blood Institute, National Institutes of Health.

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Diabetic patients are characterised by poorer prognosis and more cardiovascular complications compared with non-diabetic patients, which may be due to metabolic abnormalities and atherosclerotic plaque characteristics. METHODS:Patients with unstable angina pectoris were enrolled in the study and divided int...

journal_title：Atherosclerosis

authors： Feng T,Yundai C,Lian C,Zhijun S,Changfu L,Jun G,Hongbin L

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of resistance training (RT) on the metabolism of an LDL-like nanoemulsion and on lipid transfer to HDL, an important step of HDL metabolism. METHODS:LDL-like nanoemulsion plasma kinetics was studied in 15 healthy men under regular RT for 1-4 years (age = 25 ± 5 years, VO(2)peak = 50 ±...

journal_title：Atherosclerosis

authors： da Silva JL,Vinagre CG,Morikawa AT,Alves MJ,Mesquita CH,Maranhão RC

更新日期：2011-12-01 00:00:00

abstract：:Dietary linoleate was effective to increase LDL fluidity in adult men but did not significantly influence VLDL or HDL fluidities. Lipoproteins were isolated ultracentrifugally from plasma of sixteen healthy, free living male volunteers consuming controlled diets formulated from typical U.S.A. foods to have 35 energy %...

journal_title：Atherosclerosis

authors： Berlin E,Judd JT,Marshall MW,Kliman PG

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND AND AIMS:We aimed at developing a novel risk prediction model for death from cardiovascular disease (CVD) for Chinese individuals, based upon a large cohort from Taiwan. METHODS:This Chinese cohort came from Taiwan, with 381,963 individuals free from CVD, recruited from a private health surveillance program...

journal_title：Atherosclerosis

authors： Hu WS,Lee JH,Tsai MK,Wen CP

更新日期：2017-09-01 00:00:00

abstract：:The risk factors for cardiovascular disease are related directly or indirectly in women, as in men, to lipid and lipoprotein levels. But women have the advantage of the beneficial effects of either endogenous or exogenous estrogen on these levels throughout most of their lives. Behaviors such as smoking or diseases su...

journal_title：Atherosclerosis

authors： Miller VT

更新日期：1994-08-01 00:00:00

abstract：:Ciprofibrate is an effective treatment for three main types of atherogenic hyperlipoproteinaemia: type IIa hypercholesterolaemia, type IIb combined hyperlipidaemia, and type IV hypertriglyceridaemia. In type IIa hypercholesterolaemia, administration of 100 mg/day of ciprofibrate, to approximately 3000 patients, decrea...

journal_title：Atherosclerosis

authors： Turpin G,Bruckert E

更新日期：1996-07-01 00:00:00

abstract：:We previously demonstrated that hyperbaric oxygen (HBO) treatment inhibits diet-induced atherosclerosis in New Zealand White rabbits. In the present study we investigate the mechanisms that might be involved in the athero-protective effect of HBO treatment in a well-accepted model of atherosclerosis, the apoE knockout...

journal_title：Atherosclerosis

authors： Kudchodkar BJ,Pierce A,Dory L

更新日期：2007-07-01 00:00:00

abstract：:A recent study has suggested that symptoms of chronic bronchitis predict the risk of coronary disease independently of the known major cardiovascular risk factors. High serum levels of lipoprotein(a) (Lp(a)) have also been considered as an independent risk factor for coronary heart disease. Therefore, the aim of the p...

journal_title：Atherosclerosis

authors： Basili S,Ferroni P,Vieri M,Cardelli P,Ceci F,Paradiso M,Labbadia G,Gazzaniga PP,Cordova C,Alessandri C

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:The goal of the study was to examine possible sex-related differences in the clinical characteristics and risk factors in Japanese patients with peripheral arterial disease (PAD). METHODS:Sex-related differences in clinical profiles, risk factors and treatments were examined in 730 consecutive patients with ...

journal_title：Atherosclerosis

authors： Kumakura H,Kanai H,Araki Y,Kasama S,Sumino H,Ito T,Iwasaki T,Takayama Y,Ichikawa S,Fujita K,Nakashima K,Minami K

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Allergic asthma can accelerate atherosclerosis, a disease in which plaque is deposited onto arterial walls and that may lead to coronary artery disease (CAD). Eosinophils are the most important effector cells in allergic asthma and are likely to become novel biomarkers for risk stratification of pat...

journal_title：Atherosclerosis

authors： Gao S,Deng Y,Wu J,Zhang L,Deng F,Zhou J,Yuan Z,Wang L

更新日期：2019-07-01 00:00:00

abstract：:Although the standard procedure for preparing extensively oxidized low-density lipoprotein (Ox-LDL) is to incubate it with 10muM CuSO(4) at 37 degrees C for 24h, it is not well known how important the degree of oxidation of LDL is for inducing cell signaling. Since Lox-1 (an Ox-LDL receptor) contributes to cell prolif...

journal_title：Atherosclerosis

authors： Tanigawa H,Miura S,Zhang B,Uehara Y,Matsuo Y,Fujino M,Sawamura T,Saku K

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Previous epidemiological studies have shown positive associations between serum calcium concentration and risk of cardiovascular disease (CVD), but results differ by definition of CVD. We examined the association of circulating calcium with incident and fatal CVD, myocardial infarction (MI), and str...

journal_title：Atherosclerosis

authors： Rohrmann S,Garmo H,Malmström H,Hammar N,Jungner I,Walldius G,Van Hemelrijck M

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:Atherosclerosis and other cardiovascular diseases are serious threats to human health and become the leading cause of death in the world. Emerging evidence reveals that inhibition of plaque neovascularization could be an effective approach for the treatment of atherosclerosis. This study was conducted to iden...

journal_title：Atherosclerosis

authors： Xie S,Dong B,Sun X,Tala,He X,Zhou J,Liu M,Li D

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Uric acid is frequently elevated in hypertension. In addition to renal and metabolic disturbances, lower limb ischemia might contribute to hyperuricemia among hypertensives complicated by peripheral arterial disease (PAD). OBJECTIVE:To test the hypothesis that uric acid status is related to lower limb funct...

journal_title：Atherosclerosis

authors： Langlois M,De Bacquer D,Duprez D,De Buyzere M,Delanghe J,Blaton V

更新日期：2003-05-01 00:00:00

abstract：:We investigated the differences between the hypocholesterolemic effects induced by dietary linoleic acid and those induced by oleic acid in hamsters. Addition of 5% linoleic acid or oleic acid to a 0.1% cholesterol-supplemented diet diminished the increases in plasma total and low density lipoprotein (LDL) cholesterol...

journal_title：Atherosclerosis

authors： Kurushima H,Hayashi K,Toyota Y,Kambe M,Kajiyama G

更新日期：1995-04-24 00:00:00

abstract：:Statins produce cholesterol-independent, anti-inflammatory effects, which result at least in part from increased endothelial nitric oxide production. These effects may be modulated by polymorphisms in the endothelial nitric oxide synthase (eNOS) gene. Here, we examined whether the T-786C polymorphism of eNOS gene affe...

journal_title：Atherosclerosis

authors： Souza-Costa DC,Sandrim VC,Lopes LF,Gerlach RF,Rego EM,Tanus-Santos JE

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:How 9p21 variation affects risk of cardiovascular disease is unclear, so we assessed whether 9p21 variants are associated with arterial elasticity or retinal microvascular findings. METHODS:In the prospective Multi-Ethnic Study of Atherosclerosis (MESA) we assessed 378 SNPs in the 9p21 locus. Within four eth...

journal_title：Atherosclerosis

authors： Folsom AR,Pankow JS,Li X,Duprez DA,Jacobs DR Jr,Klein R,Klein B,Tang W,Wong TY,Cotch MF,Taylor KD,Rich SS,Hall JL,Post WS,Rotter JI

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Thrombocytopenia in scavenger receptor BI (SR-BI) knockout mice is suggested to result from augmented platelet clearance induced by elevated intracellular unesterified cholesterol (UC) levels. We hypothesize that SR-BI deficiency may also influence platelet production at the level of its precursor c...

journal_title：Atherosclerosis

authors： Ouweneel AB,Hoekstra M,van der Wel EJ,Schaftenaar FH,Snip OSC,Hassan J,Korporaal SJA,Van Eck M

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND AIMS:In Switzerland, the prevalence of familial hypercholesterolemia (FH) due to pathogenic apolipoprotein B-100 gene (APOB) variants was known, but not the prevalence of FH due to pathogenic low-density lipoprotein-receptor gene (LDLR) variants. Phenotypic differences (LDLR versus APOB) might affect the...

journal_title：Atherosclerosis

authors： Miserez AR,Martin FJ,Spirk D

更新日期：2018-10-01 00:00:00

abstract：:No evidence of premature vascular disease is found in apolipoprotein A-I(Milano) (apoA-I(M)) human carriers, despite very low high density lipoprotein (HDL) cholesterol levels. Whether apoA-I(M) may impart a "gain of function" in atherosclerosis protection compared to wild-type apoA-I is hotly debated. To address this...

journal_title：Atherosclerosis

authors： Parolini C,Chiesa G,Gong E,Caligari S,Cortese MM,Koga T,Forte TM,Rubin EM

更新日期：2005-12-01 00:00:00

abstract：:Randomized lard and butter oil were conpared with native lard and butter oil for their effects on cholesterol-induced atherosclerosis in rabbits. In each experiment there was also a group fed corn oil. The diets contained 2% cholesterol and 6% fat and were fed for eight weeks. Randomization of either butter or lard ha...

journal_title：Atherosclerosis

authors： Kritchevsky D,Tepper SA

更新日期：1977-07-01 00:00:00

abstract：OBJECTIVE:Vascular calcification is an active deposition process of calcium phosphate which resembles bone formation and is highly regulated by osteoblast-like cells. Existing studies demonstrate that advanced glycation end-products (AGEs) may play a pathogenic role in the vascular calcification process. However, their...

journal_title：Atherosclerosis

authors： Wang Z,Jiang Y,Liu N,Ren L,Zhu Y,An Y,Chen D

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Bone marrow (BM)-derived progenitor cells are functionally impaired in patients with ischemic heart disease (IHD), thereby hampering the outcome of autologous stem cell therapy. In search for underlying mechanisms for this BM dysfunction, accelerated cellular senescence was explored. METHODS:We ana...

journal_title：Atherosclerosis

authors： Nollet E,Hoymans VY,Rodrigus IR,De Bock D,Dom M,Van Hoof VOM,Vrints CJ,Van Craenenbroeck EM

更新日期：2017-05-01 00:00:00