The influence of low intake of n-3 fatty acids on platelets in elderly people.

abstract：:Men with ankylosing spondylitis (AS) and females with systemic lupus erythematosus (SLE) were found to have low total serum lipid concentrations similar to results previously obtained in patients with rheumatoid arthritis (RA). In AS men total serum TG was about 50% of control values and in AS men and SLE women total ...

journal_title：Atherosclerosis

authors： Rössner S

更新日期：1978-09-01 00:00:00

abstract：:The aim of this study is to assess the relationship of epicardial adipose tissue (EAT) and plaque vulnerability. We consecutively enrolled 82 patients with coronary artery disease (CAD). A symptom-related vessel was imaged by virtual histology intravascular ultrasound (VH-IVUS). In 60 out of 82 patients, all three ves...

journal_title：Atherosclerosis

authors： Park JS,Choi SY,Zheng M,Yang HM,Lim HS,Choi BJ,Yoon MH,Hwang GS,Tahk SJ,Shin JH

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Patients with beta-thalassemia major (beta-TM) demonstrate an increased incidence of vascular complications, which are thought to result from a procoagulant/proinflammatory environment. We investigated the arterial vasorelaxing capacity and sought for early carotid atherosclerosis and underlying pathophysiol...

journal_title：Atherosclerosis

authors： Hahalis G,Kremastinos DT,Terzis G,Kalogeropoulos AP,Chrysanthopoulou A,Karakantza M,Kourakli A,Adamopoulos S,Tselepis AD,Grapsas N,Siablis D,Zoumbos NC,Alexopoulos D

更新日期：2008-06-01 00:00:00

abstract：:The effects of atorvastatin (Lipitor) were evaluated in 40 patients with familial hypercholesterolemia (FH). Following a 6 week drug-free baseline period 20 male and 20 female patients were treated with atorvastatin 40 mg once daily (QD) for the initial 6 weeks increasing to 80 mg QD during the following 6 weeks. Ator...

journal_title：Atherosclerosis

authors： Hoogerbrugge N,Jansen H

更新日期：1999-09-01 00:00:00

abstract：:Endurance exercise training is known to produce favorable changes in the metabolic profile including reduced plasma triglyceride (TG) and increased high-density lipoprotein (HDL) cholesterol concentrations. These metabolic improvements are likely to contribute to the reduced coronary heart disease (CHD) risk often obs...

journal_title：Atherosclerosis

authors： Bergeron J,Couillard C,Després JP,Gagnon J,Leon AS,Rao DC,Skinner JS,Wilmore JH,Bouchard C

更新日期：2001-12-01 00:00:00

abstract：:We present the case of a 42-year-old male with familial hypercholesterolemia (FH) who had received long-term low-density lipoprotein (LDL)-apheresis before death occurred, presumably from an arrhythmia. He had been treated with double filtration plasmapheresis (DFPP) for 4 years and selective LDL adsorbent plasmaphere...

journal_title：Atherosclerosis

authors： Koga N,Iwata Y

更新日期：1991-09-01 00:00:00

abstract：:The effectiveness of a new, almost l-thyroxine free preparation of d-thyroxine (Dynothel) was tested in 15 patients with Type IIa and 4 patients with Type IIb hyperlipoproteinemia. Eleven patients with Type IIa and 3 with Type IIb were responsive to treatment and showed an average 26% decrease in plasma TC. This decre...

journal_title：Atherosclerosis

authors： Rakow AD,Klor HU,Kuter E,Ditschuneit HH,Ditschuneit H

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND AND AIM:Hypercholesterolaemia is a major risk factor for atherosclerosis. Cholesterol is modulated by genetic and environmental factors. An important regulatory pathway is controlled by the sterol-regulatory element-binding proteins (SREBPs) and the SREBP cleavage-activating protein (SCAP). Both SREBP-2 and ...

journal_title：Atherosclerosis

authors： Durst R,Jansen A,Erez G,Bravdo R,Butbul E,Ben Avi L,Shpitzen S,Lotan C,Leitersdorf E,Defesche J,Friedlander Y,Meiner V,Miserez AR

更新日期：2006-12-01 00:00:00

abstract：:To clarify age-related and lipid-related hemostatic abnormalities in the elderly, we measured the plasma levels of active PAI-1 antigen (aPAI-1), tPA-PAI-1 complex (TPC), plasminogen, alpha 2-plasmin inhibitor (alpha 2-PI), plasmin-alpha 2-PI complex (PIC), and D-dimer, together with the plasma levels of fibrinogen, f...

journal_title：Atherosclerosis

authors： Kario K,Matsuo T

更新日期：1993-11-01 00:00:00

abstract：:The response to therapy with hypolipidemic agents shows considerable individual variation. These differences may be due to the interaction of environmental and genetic factors that affect drug bioavailability, receptor function or ligand structure. Our objective was to assess the effect of apolipoprotein (apo) E genot...

journal_title：Atherosclerosis

authors： Pedro-Botet J,Schaefer EJ,Bakker-Arkema RG,Black DM,Stein EM,Corella D,Ordovas JM

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Both elevated serum uric acid (SUA) and peripheral endothelial dysfunction (PED) are associated independently with cardiovascular disease (CVD). However, the association between SUA and PED is yet to be established. We hypothesized that high normal range of SUA is associated with PED. METHODS:We pe...

journal_title：Atherosclerosis

authors： Taher R,Sara JD,Prasad M,Kolluri N,Toya T,Lerman LO,Lerman A

更新日期：2019-11-01 00:00:00

abstract：:Laying and genetically defective non-laying hens were evaluated for plasma lipid and plasma peroxidation levels. The non-layers developed extreme hyperlipidemia as well as greatly increased levels of lipid peroxidation. It was concluded that the concurrent presence of lipid peroxidation products must be considered whe...

journal_title：Atherosclerosis

authors： Smith T,Toda T,Kummerow FA

更新日期：1985-10-01 00:00:00

abstract：:High density lipoprotein cholesterol (HDL-C) is a primary risk factor for cardiovascular disease. Apolipoprotein A-1 (apoA1) is the major HDL-associated apolipoprotein. The -75G/A single nucleotide polymorphism (SNP) in the apolipoprotein A1 gene (APOA1) promoter has been reported to be associated with HDL-C concentra...

journal_title：Atherosclerosis

authors： Ruaño G,Seip RL,Windemuth A,Zöllner S,Tsongalis GJ,Ordovas J,Otvos J,Bilbie C,Miles M,Zoeller R,Visich P,Gordon P,Angelopoulos TJ,Pescatello L,Moyna N,Thompson PD

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:High homocysteine level is a risk factor for atherosclerosis and has been associated with lacunar infarcts (LIs), white matter lesions (WML) and cognitive dysfunction. It is unclear whether homocysteine is associated with cerebral small vessel disease (cSVD) on top of pre-existent atherosclerosis. We evaluate...

journal_title：Atherosclerosis

authors： Kloppenborg RP,Nederkoorn PJ,van der Graaf Y,Geerlings MI

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:It is unclear whether individuals experience specific patterns of morbidity prior to premature death from cardiovascular disease (CVD). METHODS:We examined morbidity levels in the 6 years leading up to death from CVD in 37,397 men and 113,198 women under 65 years of age from the Finnish Public Sector study,...

journal_title：Atherosclerosis

authors： Singh-Manoux A,Kivimäki M,Sjösten N,Ferrie JE,Nabi H,Pentti J,Virtanen M,Oksanen T,Vahtera J

更新日期：2010-08-01 00:00:00

abstract：:Statins are widely used for treatment of hypercholesterolemia. Recent experimental studies revealed that these drugs also exert anti-inflammatory effects. The aim of this study was to assess immunomodulatory effects of statins in humans in vivo. Twenty-seven healthy volunteers were analyzed for serum cytokines and acu...

journal_title：Atherosclerosis

authors： Fehr T,Kahlert C,Fierz W,Joller-Jemelka HI,Riesen WF,Rickli H,Wüthrich RP,Ammann P

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:As apoE(-/-) and LDL-Receptor(-/-) mice are commonly used in atherosclerosis research; our objective was to point out the differences in HDL metabolism between mice and humans regarding the roles of apoE and LDLR. METHODS:We examined HDL particles obtained from wild type (WT), LDLR(-/-), and apoE(-/-) mice, ...

journal_title：Atherosclerosis

authors： Tani M,Matera R,Horvath KV,Hasan TS,Schaefer EJ,Asztalos BF

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The exact mechanism of premature atherosclerosis in diabetes is still unclear. Inappropriate activation of the renin-aldosterone-angiotensin system may be an important risk factor for cardiovascular disease. We investigated whether renin and aldosterone are associated with vasoactive peptides midreg...

journal_title：Atherosclerosis

authors： Then C,Rottenkolber M,Lechner A,Meisinger C,Heier M,Koenig W,Peters A,Rathmann W,Bidlingmaier M,Reincke M,Seissler J

更新日期：2016-09-01 00:00:00

abstract：:Hypertriglyceridemia affects approximately 33% of the US population. Elevated triglyceride levels are independently associated with cardiovascular disease (CVD) risk, and severe hypertriglyceridemia is a risk factor for acute pancreatitis. Guidelines for the management of severe hypertriglyceridemia (≥5.6 mmol/L [≥500...

journal_title：Atherosclerosis

authors： Ito MK

更新日期：2015-10-01 00:00:00

abstract：:This study sought to examine the association between cigarette smoking and serum bilirubin antioxidant concentrations in 715 middle-aged men undergoing coronary angiography. The study involved 153 current smokers, 251 who quit smoking and 311 who never smoked. Serum bilirubin concentrations were divided into the follo...

journal_title：Atherosclerosis

authors： Schwertner HA

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVE:To study the influence of polyvascular atherothrombotic disease on stroke patient prognosis, its relation with inflammatory markers, and to analyze the progression of atherothrombotic disease. METHODS:MITICO is a multi-centered prospective observational study recruiting non-anticoagulated ischemic stroke pat...

journal_title：Atherosclerosis

authors： Blanco M,Sobrino T,Montaner J,Medrano V,Jiménez C,Masjuán J,Gómez-Escalonilla C,de Luis P,Arboix A,Castillo J,MITICO Study.

更新日期：2010-02-01 00:00:00

abstract：:High-density lipoprotein (HDL) cholesteryl esters (CE) are taken up by many cells without parallel uptake of HDL apolipoproteins. This selective uptake of HDL CE was investigated in human monocyte-derived macrophages (HMM). HDL3 (d = 1.125-1.21 g/ml) was labeled in its apolipoprotein A-I moiety with 125I and in its CE...

journal_title：Atherosclerosis

authors： Rinninger F,Deichen JT,Jäckle S,Windler E,Greten H

更新日期：1994-02-01 00:00:00

abstract：:The local anesthetic lidocaine was studied for its effects on lipid metabolism in aortas from normal rats, rabbits, and cholesterol-fed (atherosclerotic) rabbits in vitro. Incubation of aortas in the presence of 3--5 mM lidocaine resulted in a statistically significant reduction in the incorporation of [14C]oleate int...

journal_title：Atherosclerosis

authors： Bell FP,Hubert EV

更新日期：1981-07-01 00:00:00

abstract：:Enhanced and prolonged postprandial lipaemia is implicated in coronary and carotid artery disease. This study assessed the effects of atorvastatin, a 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor, on postprandial plasma concentrations of triglyceride-rich lipoproteins (TRLs). Sixteen middle-aged men with combined...

journal_title：Atherosclerosis

authors： Boquist S,Karpe F,Danell-Toverud K,Hamsten A

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND AIMS:The optimal approaches to management of patients treated with moderate statin doses on lipid parameters are unknown. The ACCENTUATE study aimed to compare the effects of adding the cholesteryl ester transfer protein inhibitor (CETP) evacetrapib, ezetimibe or increasing statin dose in atorvastatin-tr...

journal_title：Atherosclerosis

authors： Nicholls SJ,Ray KK,Ballantyne CM,Beacham LA,Miller DL,Ruotolo G,Nissen SE,Riesmeyer JS,ACCENTUATE Investigators.

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Common variants at the 2q36.3-IRS1 locus are associated with insulin resistance (IR), type 2 diabetes (T2D) and coronary artery disease (CAD) in large-scale association studies. We tested the hypothesis that variants at this locus are associated with subclinical atherosclerosis traits. METHODS:We studied 274...

journal_title：Atherosclerosis

authors： Lim S,Hong J,Liu CT,Hivert MF,White CC,Murabito JM,O'Donnell CJ,Dupuis J,Florez JC,Meigs JB

更新日期：2013-07-01 00:00:00

abstract：:We investigated the effects of estrogen and simvastatin, administered both alone and in combination, on the plasma lipid levels and lipoprotein-related enzymes in 45 postmenopausal women with type IIa hypercholesterolemia. They received 0.625 mg conjugated equine estrogen (n=15), 5 mg simvastatin (n=15), or the combin...

journal_title：Atherosclerosis

authors： Wakatsuki A,Okatani Y,Ikenoue N

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Lipoprotein Lp(a) has been shown to be an independent risk factor for coronary artery disease (CAD). However, its association with CAD burden in patients with ACS is largely unknown, as well as the association of Lp(a) with lipid rich plaques prone to rupture. AIM:We aim at assessing CAD burden by coronary ...

journal_title：Atherosclerosis

authors： Niccoli G,Cin D,Scalone G,Panebianco M,Abbolito S,Cosentino N,Jacoangeli F,Refaat H,Gallo G,Salerno G,Volpe M,Crea F,De Biase L

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Type 2 diabetes (DM2) and impaired glucose metabolism (IGM) are associated with an increased cardiovascular disease risk. Impaired endothelial synthesis of nitric oxide (NO) is an important feature of atherothrombosis and can be estimated from endothelium-dependent flow-mediated dilation (FMD). It is controv...

journal_title：Atherosclerosis

authors： Henry RM,Ferreira I,Kostense PJ,Dekker JM,Nijpels G,Heine RJ,Kamp O,Bouter LM,Stehouwer CD

更新日期：2004-05-01 00:00:00

abstract：:Inflammatory cytokine synthesis by monocyte-macrophages in the developing plaque represents an important amplification point in atherosclerotic disease progression. Here we have investigated whether the state of monocyte-macrophage differentiation can influence TNF alpha synthesis in response to scavenged modified low...

journal_title：Atherosclerosis

authors： Smythe CD,Skinner VO,Bruckdorfer KR,Haskard DO,Landis RC

更新日期：2003-10-01 00:00:00