Lipoprotein(a) serum levels in patients affected by chronic obstructive pulmonary disease.

abstract：SUMMARY:A type of spontaneous arteriosclerosis, described as medial sclerosis and quite distinct from atherosclerosis, was found in the aortas, coronary arteries and aortic branch arteries of free-living elephants (Loxodonta africana) in Uganda and Kenya. The lesions took the form of calcified fibrotic plaques in the i...

journal_title：Atherosclerosis

authors： McCullagh KG

更新日期：1975-01-01 00:00:00

abstract：:Lack of physical activity appears to have deleterious effects on serum lipoproteins. Twenty-three patients who were completely immobilised by traumatic fracture of the spine had significantly lower (P < 0.001) plasma high density lipoprotein cholesterol (HDL-C) and apolipoprotein A-I levels than normally mobile paired...

journal_title：Atherosclerosis

authors： Nikkilä EA,Kuusi T,Myllynen P

更新日期：1980-11-01 00:00:00

abstract：OBJECTIVE:Low levels of high density lipoprotein-cholesterol (HDL-C) are highly prevalent in subjects presenting premature atherosclerosis. It is indeterminate as to whether high cardiovascular risk in low HDL-C subjects occurs concomitantly with elevated oxidative stress and/or with biologically dysfunctional HDL part...

journal_title：Atherosclerosis

authors： Kontush A,de Faria EC,Chantepie S,Chapman MJ

更新日期：2005-10-01 00:00:00

abstract：:The present study analysed the effects of hydroxytyrosol (HT) on blood lipids, antioxidant status and the progression of aortic lesions in hyperlipemic rabbits. Sixty-four rabbits were distributed into eight groups of animals (n = 8). Animal groups C, A and H were fed for 1-month with a control diet containing sunflow...

journal_title：Atherosclerosis

authors： González-Santiago M,Martín-Bautista E,Carrero JJ,Fonollá J,Baró L,Bartolomé MV,Gil-Loyzaga P,López-Huertas E

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:To examine whether the beneficial effects of PJ consumption by mice on their macrophages are mediated via PJ-induced increment in serum paraoxonase 1 (PON1) activity and/or in macrophage PON2 expression. METHODS AND RESULTS:We performed studies in peritoneal macrophages (MPM) from C57BL/6 control mice, or fr...

journal_title：Atherosclerosis

authors： Rosenblat M,Volkova N,Aviram M

更新日期：2010-09-01 00:00:00

abstract：:Familial hypobetalipoproteinemia is an autosomal co-dominant disorder, which in a minority of cases is due to a truncation producing mutation in the apoB gene. We have identified an apoB mutation in a 40-year old hypobetalipoproteinemic man with Type II diabetes mellitus. Immunoblotting of plasma revealed a major band...

journal_title：Atherosclerosis

authors： Pulai JI,Latour MA,Kwok PY,Schonfeld G

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Left-sided valvular calcification is associated with cardiovascular disease (CVD) morbidity and mortality. Resting heart rate (RHR) may influence valvular calcium progression through shear stress. Whether RHR, an established CVD risk factor, is associated with valvular calcium progression is unknown...

journal_title：Atherosclerosis

authors： Amoakwa K,Fashanu OE,Tibuakuu M,Zhao D,Guallar E,Whelton SP,O'Neal WT,Post WS,Budoff MJ,Michos ED

更新日期：2018-06-01 00:00:00

abstract：:We investigated the effects of estrogen and simvastatin, administered both alone and in combination, on the plasma lipid levels and lipoprotein-related enzymes in 45 postmenopausal women with type IIa hypercholesterolemia. They received 0.625 mg conjugated equine estrogen (n=15), 5 mg simvastatin (n=15), or the combin...

journal_title：Atherosclerosis

authors： Wakatsuki A,Okatani Y,Ikenoue N

更新日期：2000-05-01 00:00:00

abstract：:Evidence suggests low vitamin D and elevated parathyroid hormone (PTH) concentrations may increase risk for cardiovascular disease. However, little is known about the association between vitamin D or PTH and subclinical atherosclerosis. This cross-sectional study included 654 community-dwelling older adults aged 55-96...

journal_title：Atherosclerosis

authors： Reis JP,von Mühlen D,Michos ED,Miller ER 3rd,Appel LJ,Araneta MR,Barrett-Connor E

更新日期：2009-12-01 00:00:00

abstract：:This study was aimed to test the hypothesis that noninvasive assessment of carotid plaques can be achieved by high-resolution micro-ultrasound imaging in apolipoprotein-E knockout (apoE-KO) mice. Forty-two male apoE-KO mice were fed a high-fat diet and atherosclerotic lesions in the left common carotid artery were ind...

journal_title：Atherosclerosis

authors： Ni M,Zhang M,Ding SF,Chen WQ,Zhang Y

更新日期：2008-03-01 00:00:00

abstract：:The response to therapy with hypolipidemic agents shows considerable individual variation. These differences may be due to the interaction of environmental and genetic factors that affect drug bioavailability, receptor function or ligand structure. Our objective was to assess the effect of apolipoprotein (apo) E genot...

journal_title：Atherosclerosis

authors： Pedro-Botet J,Schaefer EJ,Bakker-Arkema RG,Black DM,Stein EM,Corella D,Ordovas JM

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Psychological stress (PS) has been associated with the development of cardiovascular diseases and adverse long-term outcomes after ischemic events. However, the precise mechanisms involved are not completely understood. Here we investigated the effect of PS on ischemia-induced neovascularization, and the pot...

journal_title：Atherosclerosis

authors： Maingrette F,Dussault S,Dhahri W,Desjarlais M,Mathieu R,Turgeon J,Haddad P,Groleau J,Perez G,Rivard A

更新日期：2015-08-01 00:00:00

abstract：:Leukotriene B(4) (LTB(4)) is a pro-inflammatory lipid mediator generated by the enzymes 5-lipoxygenase (5-LO) and LTA(4)-hydrolase. LTB(4) signals primarily through its G protein-coupled receptor BLT1, which is highly expressed on specific leukocyte subsets. Recent genetic studies in humans as well as knockout studies...

journal_title：Atherosclerosis

authors： Kristo F,Hardy GJ,Anderson TJ,Sinha S,Ahluwalia N,Lin AY,Passeri J,Scherrer-Crosbie M,Gerszten RE

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Leukocyte count is recognized as an inflammatory marker and a predictor of cardiovascular events. However, it is uncertain whether the contribution of leukocyte count to the risk of cardiovascular disease is independent of smoking. METHODS:The subjects were 4492 male employees aged 40-59 years who worked fo...

journal_title：Atherosclerosis

authors： Imano H,Sato S,Kitamura A,Kiyama M,Ohira T,Shimamoto T,Iso H

更新日期：2007-11-01 00:00:00

abstract：:Coronary arteries with and without atheroma are compared histologically to ask what kind of artery encourages atheroma. When atheroma obliterates the structures that preceded and invited its intrusion, the sites remaining for observation form a censored data set. How to assess media-like island effects using the censo...

journal_title：Atherosclerosis

authors： Tracy RE

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Peritoneal macrophages are used in many studies related to atherosclerosis. In situ, they are non-adherent and upon culturing, they adhere and function as scavengers of modified lipoproteins and dead apoptotic cells. They also produce growth factors, suggesting that they may provide life-supporting function a...

journal_title：Atherosclerosis

authors： Selvarajan K,Moldovan L,Chandrakala AN,Litvinov D,Parthasarathy S

更新日期：2011-12-01 00:00:00

abstract：:Incorporation of 125I-labeled cholesterol ester rich lipoproteins from cholesterol fed rabbits into normal rabbit aorta in vitro was inhibited by heparin, lecithin, and collagenase and by succinylation of the lipoprotein. Aortic uptake of lipoprotein was increased by neuraminidase, proteases, lipase, and beta-glucuron...

journal_title：Atherosclerosis

authors： Day CE

更新日期：1976-11-01 00:00:00

abstract：:Forty patients with NIDDM and hyperlipoproteinemia were selected for a 12-week double-blind placebo-controlled trial to study the effects of metformin on lipoprotein concentration and composition. A significant decrease occurred in VLDL-apo B and all lipid components of VLDL, indicating a decreased number of circulati...

journal_title：Atherosclerosis

authors： Schneider J,Erren T,Zöfel P,Kaffarnik H

更新日期：1990-05-01 00:00:00

abstract：:Familial combined hyperlipidemia (FCHL) is one of the most common inherited lipid disorders. Resistance of adipocytes to the effects of acylation stimulating protein (ASP) may contribute to ineffective triglyceride synthesis and thereby prolonged postprandial lipemia and increased fatty acid flux to the liver seen in ...

journal_title：Atherosclerosis

authors： Ylitalo K,Porkka KV,Meri S,Nuotio I,Suurinkeroinen L,Vakkilainen J,Pajukanta P,Viikari JS,Peltonen L,Ehnholm C,Taskinen MR

更新日期：1997-03-21 00:00:00

abstract：:Mevinolin (MK-803) is a potent inhibitor of HMG-CoA reductase. After a placebo run-in period, mevinolin 5,15 or 50 mg, or placebo was given twice daily for 7-11 days under double -blind conditions ot 4 groups of 6 normocholesterolemic male volunteers. After 7 days, mean serum cholesterol fell 14%, 25% and 24% on 5, 15...

journal_title：Atherosclerosis

authors： Tobert JA,Hitzenberger G,Kukovetz WR,Holmes IB,Jones KH

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:DJ-1-a multifunctional protein responding to oxidative stress-is a possible regulator of the inflammatory response that plays an important role in atherosclerosis. Stromal cell-derived factor (SDF)-1 and its receptor, chemokine receptor type 4 (CXCR4), have been implicated in the recruitment of inflammatory c...

journal_title：Atherosclerosis

authors： Jung SH,Won KJ,Lee KP,Lee DH,Yu S,Lee DY,Seo EH,Kang H,Park ES,Kim HJ,Lee SH,Kim B

更新日期：2014-08-01 00:00:00

abstract：:The prevalence of coronary heart disease (CHD), cardiovascular disease (CVD) and associated risk factors was studied in 413 men aged 70-89, the survivors of the Finnish cohorts of the Seven Countries Study. Men were divided into five categories according to manifestations of prevalent CVD: I, history or ECG evidence o...

journal_title：Atherosclerosis

authors： Tervahauta M,Pekkanen J,Kivinen P,Stengård J,Jauhiainen M,Ehnholm C,Nissinen A

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of pioglitazone on endothelial and adipose tissue dysfunction in newly detected IGT patients with CAD. METHODS AND DESIGN:Participants (n=25) were randomized to treatment with either placebo or pioglitazone (30 mg/day) for 12 weeks. Before and after treatment we evaluated endothelia...

journal_title：Atherosclerosis

authors： Rizza S,Cardellini M,Porzio O,Pecchioli C,Savo A,Cardolini I,Senese N,Lauro D,Sbraccia P,Lauro R,Federici M

更新日期：2011-03-01 00:00:00

abstract：:The effect of 4 months of low-dose probucol treatment (250 mg/day) on LDL oxidation and on plasma-HDL cholesterol was studied in a prospective, double-blind, randomized, placebo-controlled trial involving 26 male volunteers. LDL samples isolated at baseline and at 4 months were subjected to in vitro tests of LDL oxida...

journal_title：Atherosclerosis

authors： Cristol LS,Jialal I,Grundy SM

更新日期：1992-11-01 00:00:00

abstract：:Intimal proliferation and functional changes involving vascular smooth muscle cells are key events in the development of atherosclerosis, including restenosis after percutaneous transluminal angioplasty. Nonmuscle myosin (NMM) is required for cytokinesis and has been shown in cultures of vascular smooth muscle cells t...

journal_title：Atherosclerosis

authors： Nikol S,Murakami N,Pickering JG,Kearney M,Leclerc G,Höfling B,Isner JM,Weir L

更新日期：1997-04-01 00:00:00

abstract：INTRODUCTION:Cardio- and/or cerebro-vascular risk are associated with high lipoprotein (a) [Lp(a)] levels and low-molecular-weight (LMW) apo(a) isoforms. Aims of this study were to evaluate the deposition of apo(a) isoforms and apoprotein B (apo B) in atherosclerotic plaque from patients (males and females) who had car...

journal_title：Atherosclerosis

authors： Baldo G,Giunco S,Kontothanassis D,Baiocchi MR,Valerio A,Frego M

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Ticagrelor reduces cardiovascular events in patients with acute coronary syndrome (ACS). Recent studies demonstrated the expression of P2Y12 on vascular cells including endothelial cells, as well as platelets, and suggested its contribution to atherogenesis. We investigated whether ticagrelor attenu...

journal_title：Atherosclerosis

authors： Ganbaatar B,Fukuda D,Salim HM,Nishimoto S,Tanaka K,Higashikuni Y,Hirata Y,Yagi S,Soeki T,Sata M

更新日期：2018-08-01 00:00:00

abstract：:When rabbits are fed a cholesterol-rich diet they accumulate beta-migrating very low density lipoprotein (beta-VLDL) in their plasma. beta-VLDL are cholesteryl ester-rich lipoproteins which contain apolipoproteins B and E. There are 2 forms of apolipoprotein B in beta-VLDL. About 90% of apolipoprotein B is present as ...

journal_title：Atherosclerosis

authors： Kroon PA,Thompson GM,Chao YS

更新日期：1985-09-01 00:00:00

abstract：:Serum high density lipoprotein cholesterol (HDL-C), total cholesterol (TC) and triglycerides (TG) were determined, and values of low density lipoprotein cholesterol (LDL-C), HDL-C/TC (%), and the LDL-C/HDL-C (ratio) were calculated in 1101 healthy Chinese men and women, 77 patients with coronary heart disease (CHD), 7...

journal_title：Atherosclerosis

authors： Cai HJ,Li ZX,Yang SM

更新日期：1982-06-01 00:00:00

abstract：:Ultrasound measurements are both surrogate markers and risk factors for atherosclerosis end points. Carotid intima-media thickness (IMT) is most commonly used, but ultrasound can also define structures in higher spatial dimensions, such as total plaque area (TPA) and total plaque volume (TPV). Because there are minima...

journal_title：Atherosclerosis

authors： Al-Shali K,House AA,Hanley AJ,Khan HM,Harris SB,Mamakeesick M,Zinman B,Fenster A,Spence JD,Hegele RA

更新日期：2005-02-01 00:00:00