Expression of platelet-derived growth factor B-chain in neointimal smooth muscle cells of balloon injured rabbit femoral arteries.

abstract：:The effects of chronic renal failure (CRF) and corticosteroid treatment on the aortic uptake of labelled free and esterified cholesterol (FC and EC) were investigated in normocholesterolemic rabbits. Methylprednisolone, 0.4 mg/day, or placebo was administered for 14 weeks to rabbits with normal renal function and with...

journal_title：Atherosclerosis

authors： Tvedegaard E,Szpirt W,Nielsen M

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:The CAV1 gene encodes caveolin-1 expressed in cell types relevant to atherosclerosis. Cav-1-null mice showed a protective effect on atherosclerosis under the ApoE(-/-) background. However, it is unknown whether CAV1 is linked to CAD and MI in humans. In this study we analyzed a tagSNP for CAV1 in intron 2, r...

journal_title：Atherosclerosis

authors： Chen S,Wang X,Wang J,Zhao Y,Wang D,Tan C,Fa J,Zhang R,Wang F,Xu C,Huang Y,Li S,Yin D,Xiong X,Li X,Chen Q,Tu X,Yang Y,Xia Y,Xu C,Wang QK

更新日期：2016-03-01 00:00:00

abstract：:Previous studies of leptin with cardiovascular disease (CVD) risk factors have been limited by clinical samples or lack of representation of the general population. This cross-sectional study, designed to examine whether leptin or insulin may mediate the endogenous relation of obesity with metabolic, inflammatory, and...

journal_title：Atherosclerosis

authors： Reis JP,Macera CA,Wingard DL,Araneta MR,Lindsay SP,Marshall SJ

更新日期：2008-09-01 00:00:00

abstract：:Cilostazol is an antiplatelet drug, which has beneficial effects in treatment of intermittent claudication and decreases serum triacyiglycerol level in these patients. In this study, we examined adipogenic potency of cilostazol using 3T3-L1 preadipocyte cell line because cilostazol is one of the tissue specific phosph...

journal_title：Atherosclerosis

authors： Hirose T,Kurebayashi S,Kasayama S

更新日期：2001-09-01 00:00:00

abstract：:The new millennium has brought intense focus of interest on the risk of cardiovascular disease in women. The polycystic ovary syndrome (PCOS) is a common endocrine disorder in women characterised by hyperandrogenism and oligomenorrhoea. Most women with PCOS also exhibit features of the metabolic syndrome, including in...

journal_title：Atherosclerosis

authors： Cussons AJ,Stuckey BG,Watts GF

更新日期：2006-04-01 00:00:00

abstract：:Observational studies suggested that the progression of carotid atherosclerosis and plaques might be an independent risk factor for coronary artery disease (CAD) and stroke, prior researches of different dosage of statins therapy on the progression of carotid atherosclerosis in patients had small sample sizes and diff...

journal_title：Atherosclerosis

authors： Kang S,Wu Y,Li X

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Clinical interventions targeting nonlipid risk factors are needed given the high residual risk of atherothrombotic events despite effective control of dyslipidemia. Dickkopf-1 (DKK1) plays a lipid-independent role in vascular pathophysiology but its involvement in atherosclerosis development and its...

journal_title：Atherosclerosis

authors： Rakipovski G,Rolin B,Barascuk N,Lund HE,Bjørn Bonde MF,Djordjevic D,Wulff-Larsen PG,Petersen M,Kirk RK,Hultman K,Manfe V,Blume N,Zahn S,Lengquist M,Maegdefessel L,Hovingh GK,Conde-Knape K,Hedin U,Matic L,Nyberg M

更新日期：2020-12-01 00:00:00

abstract：:The effects of insulin and insulin-like growth factor I (IGF-I) on migration, proliferation and tube-forming activity of endothelial cells were investigated, by using bovine carotid artery endothelial cells. Migration was assayed by a filter membrane technique and tube formation was assayed by a quantitative angiogene...

journal_title：Atherosclerosis

authors： Nakao-Hayashi J,Ito H,Kanayasu T,Morita I,Murota S

更新日期：1992-02-01 00:00:00

abstract：:Elevated fibrinogen levels after coronary balloon angioplasty have been reported to be useful in predicting restenosis. Therefore, we sought to evaluate the relationship between preprocedural fibrinogen levels and the 6-12-month outcomes of patients undergoing coronary stenting. Plasma levels of fibrinogen were measur...

journal_title：Atherosclerosis

authors： Otsuka M,Hayashi Y,Ueda H,Imazu M,Kohno N

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MS) is associated with dyslipidemia, and insulin resistance (IR) may be a main determinant of this dyslipidemia. OBJECTIVE:To determine how lipoprotein particle concentration and size are related to MS and IR in a population-based sample of Alaska Eskimos. DESIGN:Participants underwent ...

journal_title：Atherosclerosis

authors： Rivellese AA,Patti L,Kaufman D,Zhu J,Annuzzi G,Vaccaro O,Ebbesson SO,Howard WJ,Riccardi G,Howard BV

更新日期：2008-10-01 00:00:00

abstract：:The rates of cholesterol synthesis from acetate were studied in freshly isolated peripheral blood lymphocytes in 41 age- and sex-matched subjects with essentially normal serum lipid profiles. Insulin binding to erythrocytes obtained from the same blood samples was also studied simultaneously. From the data on lymphocy...

journal_title：Atherosclerosis

authors： Sanghvi A,Virji MA,Warty V,Dimasi MJ

更新日期：1983-12-01 00:00:00

abstract：:Low density lipoproteins extracted from surgical specimens of human atherosclerotic plaques (A-LDL) showed altered electrophoretic mobility indicating a greater negative charge than that of plasma LDL (P-LDL). A-LDL but not P-LDL showed high affinity binding/degradation by human monocyte-derived macrophages; this was ...

journal_title：Atherosclerosis

authors： Shaikh M,Martini S,Quiney JR,Baskerville P,La Ville AE,Browse NL,Duffield R,Turner PR,Lewis B

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND AND AIMS:An environment-wide association study (EWAS) may be useful to comprehensively test and validate associations between environmental factors and peripheral arterial disease (PAD) in an unbiased manner. METHODS:Data from cross-sectional cohorts from the US National Health and Nutrition Examination Sur...

journal_title：Atherosclerosis

authors： Zhuang X,Ni A,Liao L,Guo Y,Dai W,Jiang Y,Zhou H,Hu X,Du Z,Wang X,Liao X

更新日期：2018-02-01 00:00:00

abstract：:Inflammatory cytokine synthesis by monocyte-macrophages in the developing plaque represents an important amplification point in atherosclerotic disease progression. Here we have investigated whether the state of monocyte-macrophage differentiation can influence TNF alpha synthesis in response to scavenged modified low...

journal_title：Atherosclerosis

authors： Smythe CD,Skinner VO,Bruckdorfer KR,Haskard DO,Landis RC

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:Paraoxonase 1 (PON1) is a high-density lipoprotein (HDL)-associated enzyme which possess anti-atherogenic properties. Our aim was to analyze the effect of HDL phospholipids on HDL-associated paraoxonase (PON1) catalytic and biological activities. METHODS AND RESULTS:In HDL isolated from di-oleoyl-phosphatidy...

journal_title：Atherosclerosis

authors： Efrat M,Rosenblat M,Mahmood S,Vaya J,Aviram M

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND AIMS:The risk of recurrence of myocardial infarction (MI) in HIV patients presenting with acute coronary syndrome (ACS) is well known, but there is limited evidence about potential differences in coronary plaques compared to non-HIV patients. METHODS:In this multicenter case-control study, HIV patients ...

journal_title：Atherosclerosis

authors： Peyracchia M,De Lio G,Montrucchio C,Omedè P,d'Ettore G,Calcagno A,Vullo V,Cerrato E,Pennacchi M,Sardella G,Manga P,GrossoMarra W,Vullo F,Fedele F,Biondi-Zoccai G,Moretti C,Vachiat A,Bonora S,Rinaldi M,Mancone M,D'

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND AND AIM:To determine the incremental diagnostic value of epicardial adipose tissue (EAT) volume in addition to the coronary artery calcium (CAC) score for detecting hemodynamic significant coronary artery disease (CAD). METHODS AND RESULTS:122 patients (mean age 61 ± 10 years, 61% male) without a previous c...

journal_title：Atherosclerosis

authors： Romijn MA,Danad I,Bakkum MJ,Stuijfzand WJ,Tulevski II,Somsen GA,Lammertsma AA,van Kuijk C,van de Ven PM,Min JK,Leipsic J,van Rossum AC,Raijmakers PG,Knaapen P

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Carotid intima-media thickness (cIMT) is associated with CV events in adults. Thicker cIMT is found in youth with CV risk factors including obesity. Which risk factors have the most effect upon cIMT in youth and whether obesity has direct or indirect effects is not known. We used structural equation modeling...

journal_title：Atherosclerosis

authors： Gao Z,Khoury PR,McCoy CE,Shah AS,Kimball TR,Dolan LM,Urbina EM

更新日期：2016-03-01 00:00:00

abstract：:SR-12813 inhibits cholesterol biosynthesis in Hep G2 cells via an enhanced degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Here we also show that SR-12813 inhibits cholesterol biosynthesis in vivo. A sterol balance study was performed in normolipemic beagle dogs. The dogs were given SR-12813 ...

journal_title：Atherosclerosis

authors： Berkhout TA,Simon HM,Jackson B,Yates J,Pearce N,Groot PH,Bentzen C,Niesor E,Kerns WD,Suckling KE

更新日期：1997-09-01 00:00:00

abstract：:Quantitative assessment of atherosclerosis during its natural history and following therapeutic interventions is important, as cardiovascular disease remains the most significant cause of morbidity and mortality in industrial societies. While coronary angiography delineates the vessel lumen, permitting only the indire...

journal_title：Atherosclerosis

authors： von Birgelen C,Slager CJ,Di Mario C,de Feyter PJ,Serruys PW

更新日期：1995-12-01 00:00:00

abstract：:We describe a rapid screening procedure to identify known DNA sequence changes in individuals diagnosed as having heterozygous familial hypercholesterolaemia (FH). The screening is made possible by combining a rapid DNA extraction protocol and small scale polymerase chain reaction DNA amplification, followed by oligon...

journal_title：Atherosclerosis

authors： Talmud P,Tybjaerg-Hansen A,Bhatnagar D,Mbewu A,Miller JP,Durrington P,Humphries S

更新日期：1991-08-01 00:00:00

abstract：:Oxidant signalling and lipoprotein oxidation may play important roles in atherosclerotic lesion development. Given coincident localization of 15-lipoxygenase (15-LO), stereospecific products of 15-LO and epitopes of modified LDL in atherosclerotic lesions, we hypothesized that inhibition of 15-LO by PD146176, an inhib...

journal_title：Atherosclerosis

authors： Bocan TM,Rosebury WS,Mueller SB,Kuchera S,Welch K,Daugherty A,Cornicelli JA

更新日期：1998-02-01 00:00:00

abstract：:Rats were fed for 24 days a liquid diet with ethanol as 36% of calories to produce hyperlipemia and hepatic steatosis. The catabolism of chylomicrons doubly-labeled in the triacylglycerol and cholesteryl ester moieties was studied in conscious rats after ingestion of their usual liquid diets with or without ethanol. A...

journal_title：Atherosclerosis

authors： Redgrave TG,Martin G

更新日期：1977-09-01 00:00:00

abstract：:Platelet phospholipid composition was analyzed before and after extracorporeal removal of low density lipoproteins (LDL) by LDL apheresis in six patients with familial hypercholesterolemia. Elevated levels of total plasma cholesterol and the portion of plasma cholesterol carried by LDL were reduced by 56 and 66% after...

journal_title：Atherosclerosis

authors： Bräutigam R,Bräutigam C,Lorenz R,Richter WO,Engelmann B

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:To investigate associations between blood low-density lipoprotein cholesterol (LDL-C) levels and the prevalence of acquired color vision impairment (ACVI) in middle-aged Japanese men. METHODS:Participants in this cross-sectional study underwent color vision testing, ophthalmic examination, a standardized int...

journal_title：Atherosclerosis

authors： Shoji T,Sakurai Y,Sato H,Chihara E,Ishida M,Omae K

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:The association of high-density lipoprotein particle (HDL-P) with atherosclerosis may be stronger than that of HDL-cholesterol (HDL-C) and independent of conventional cardiovascular risk factors. Whether associations persist in populations at low risk of coronary heart disease (CHD) remains unclear. This stud...

journal_title：Atherosclerosis

authors： Zaid M,Fujiyoshi A,Miura K,Abbott RD,Okamura T,Takashima N,Torii S,Saito Y,Hisamatsu T,Miyagawa N,Ohkubo T,Kadota A,Sekikawa A,Maegawa H,Nakamura Y,Mitsunami K,Ueshima H,SESSA Research group.

更新日期：2015-04-01 00:00:00

abstract：:The effect of methyl prednisolone and colchicine on the development of both the early proliferative and advanced atherosclerotic lesion in swine aorta was studied. In order to accelerate the development of atherosclerosis, the abdominal aortic endothelium was partially denuded by a balloon before the animals were plac...

journal_title：Atherosclerosis

authors： Lee WM,Morrison ES,Scott RF,Lee KT,Kroms M

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Decreased nitric oxide (NO) bioavailability and increased oxidative stress may be involved in the pathogenesis of contrast-induced acute kidney injury (CI-AKI). The relationship between asymmetric dimethylarginine (ADMA), an endogenous NO synthase inhibitor, and CI-AKI is unknown. METHODS:We measur...

journal_title：Atherosclerosis

authors： Lu TM,Hsu CP,Chang CF,Lin CC,Lee TS,Lin SJ,Chan WL

更新日期：2016-11-01 00:00:00

abstract：:Evidence is emerging that the contribution of atherosclerosis to the development of abdominal aortic aneurysm may differ from that of other manifestations of arterial disease. B-mode ultrasound may be helpful in understanding the characteristics and factors that contribute to the development of different manifestation...

journal_title：Atherosclerosis

authors： Simons PC,Algra A,Bots ML,Banga JD,Grobbee DE,van der Graaf Y

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Reactive oxygen species (ROS) play a pivotal role in neointima hyperplasia after balloon injury. Molecular hydrogen has emerged as a novel antioxidant and has been proven effective in treating many diseases. OBJECTIVES:We aimed to determine the mechanism by which hydrogen affects neointima formation. METHO...

journal_title：Atherosclerosis

authors： Qin ZX,Yu P,Qian DH,Song MB,Tan H,Yu Y,Li W,Wang H,Liu J,Wang Q,Sun XJ,Jiang H,Zhu JK,Lu W,Huang L

更新日期：2012-02-01 00:00:00