Fatty acid patterns in triglycerides, diglycerides, free fatty acids, cholesteryl esters and phosphatidylcholine in serum from vegetarians and non-vegetarians.

Abstract:

:The differences in the fatty acid spectra of serum samples obtained from vegetarians (62 females, 40 males) and non-vegetarians (70 females, 38 males) were evaluated in a matched-pair study design. This study population made it possible to examine 48 female and 31 male pairs whose age difference did not exceed 3 years. The pairs were further matched by education, social status and health-consciousness. The fatty acid pattern of whole serum total lipids and HDL total lipids were determined by GLC. In particular linoleic, linolenic, oleic and docosahexaenoic acid reveal statistically significant differences due to different nutritional habits. A subsample (n = 20) of sera from the 2 groups was investigated by separation of lipid classes by TLC and GLC on a SP 2,340 fused-silica capillary column in order to separate cis-trans fatty acids additionally. This part of the study gives detailed information concerning the fatty acid composition of cholesteryl esters, triglycerides, diglycerides, free fatty acids and phosphatidylcholine. In all those fractions the fatty acid profiles reflect the dietary consumption of lipids. Palmitoleic, vaccenic and docosahexaenoic acid as markers of omnivorous nutrition reach levels of 5, 5 and 3% respectively in non-vegetarians, while they remain remarkably lower in vegetarians. The most prominent difference is the higher amount of linoleic acid in all lipid classes of vegetarian serum samples. The highest amount of trans fatty acids (up to 3%) was detected in di- and triglycerides.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Melchert HU,Limsathayourat N,Mihajlović H,Eichberg J,Thefeld W,Rottka H

doi

10.1016/0021-9150(87)90017-7

subject

Has Abstract

pub_date

1987-05-01 00:00:00

pages

159-66

issue

1-2

eissn

0021-9150

issn

1879-1484

pii

0021-9150(87)90017-7

journal_volume

65

pub_type

杂志文章
  • Association between self-reported physical activity and vascular reactivity in postmenopausal women.

    abstract::Short-term exercise training has been associated with improved endothelial-dependent vasodilation, but the impact of long-term habitual physical activity on vascular reactivity is not established. We studied the correlation between self-reported, habitual physical activity and vasoreactivity in non-smoking, non-diabet...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(01)00529-9

    authors: McKechnie R,Rubenfire M,Mosca L

    更新日期:2001-12-01 00:00:00

  • VEGF-A-induced chemotaxis of CD16+ monocytes is decreased secondary to lower VEGFR-1 expression.

    abstract:BACKGROUND:Monocyte recruitment into the vessel wall is a crucial initial step in vascular repair, arteriogenesis and atherogenesis. Two distinct human monocyte subpopulations can be classified according to their CD14/16 surface expression, namely CD14++CD16-monocytes (CD16-mo) and CD14+CD16+ monocytes (CD16+mo). We in...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2011.01.004

    authors: Czepluch FS,Olieslagers S,van Hulten R,Vöö SA,Waltenberger J

    更新日期:2011-04-01 00:00:00

  • Oxidized-LDL induce apoptosis in HUVEC but not in the endothelial cell line EA.hy 926.

    abstract::We studied the cytotoxic effect of copper-oxidized LDL in human primary human umbilical vein endothelial cells (HUVEC) and the immortalized EA.hy 926 cell line. Copper oxidized LDL (50-200 microg apoB/ml) induced concentration-dependent apoptotic cell death in HUVEC but did not induce apoptosis in EA.hy 926 cells. Onl...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(99)00170-7

    authors: Claise C,Edeas M,Chaouchi N,Chalas J,Capel L,Kalimouttou S,Vazquez A,Lindenbaum A

    更新日期:1999-11-01 00:00:00

  • Three-dimensional ultrasound imaging for the evaluation of carotid atherosclerosis.

    abstract:INTRODUCTION:Emerging data suggests that 3-dimensional (D) ultrasound (US) may provide us with a new tool for the identification of the vulnerable carotid plaque. METHODS:A systematic review of the PubMed, Scopus and Cochrane databases regarding the reproducibility and effectiveness of 3D US in evaluation of carotid p...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,评审

    doi:10.1016/j.atherosclerosis.2011.05.006

    authors: Makris GC,Lavida A,Griffin M,Geroulakos G,Nicolaides AN

    更新日期:2011-12-01 00:00:00

  • Enhanced apoB48 metabolism in lipoprotein lipase X447 homozygotes.

    abstract:RATIONALE:Lipoprotein lipase (LPL) X447 homozygotes are characterized by enhanced conversion of TRL apoB100. Here, we set out to investigate whether this LPL variant is also associated with enhanced apoB48 clearance. Therefore, we evaluated apoB48 kinetics in X447 homozygotes in the fed state by infusion of isotope L-[...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2006.08.038

    authors: Nierman MC,Rip J,Kuivenhoven JA,Sakai N,Kastelein JJ,de Sain-van der Velden MG,Stroes ES,Prinsen BH

    更新日期:2007-10-01 00:00:00

  • Small dense low-density lipoprotein cholesterol concentration and carotid atherosclerosis.

    abstract::Low-density lipoprotein cholesterol (LDL-C) and the small dense LDL (SdLDL) phenotype are both predictors for ischemic heart disease. We examined whether cholesterol of SdLDL (SdLDL-C) is more closely associated with carotid artery intima-media thickness (CA-IMT), a surrogate measure of atherosclerosis, than LDL-C and...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2008.04.042

    authors: Shoji T,Hatsuda S,Tsuchikura S,Shinohara K,Kimoto E,Koyama H,Emoto M,Nishizawa Y

    更新日期:2009-02-01 00:00:00

  • Lost work days in the 6 years leading to premature death from cardiovascular disease in men and women.

    abstract:BACKGROUND:It is unclear whether individuals experience specific patterns of morbidity prior to premature death from cardiovascular disease (CVD). METHODS:We examined morbidity levels in the 6 years leading up to death from CVD in 37,397 men and 113,198 women under 65 years of age from the Finnish Public Sector study,...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2010.04.013

    authors: Singh-Manoux A,Kivimäki M,Sjösten N,Ferrie JE,Nabi H,Pentti J,Virtanen M,Oksanen T,Vahtera J

    更新日期:2010-08-01 00:00:00

  • In vitro production of beta-very low density lipoproteins and small, dense low density lipoproteins in mildly hypertriglyceridemic plasma: role of activities of lecithin:cholester acyltransferase, cholesterylester transfer proteins and lipoprotein lipase.

    abstract::As a model for the formation of beta-very low density lipoproteins (VLDL) and small, dense LDL by the intraplasma metabolic activities in vivo, lipoproteins in fresh plasma were interacted in vitro with endogenous lecithin:cholesterol acyltransferase (LCAT) and cholesterylester transfer proteins (CETP) and subsequentl...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(98)00169-5

    authors: Chung BH,Segrest JP,Franklin F

    更新日期:1998-12-01 00:00:00

  • Relationship between brachial flow-mediated dilation and carotid intima-media thickness in an elderly cohort: the Cardiovascular Health Study.

    abstract:OBJECTIVE:The aim of this study was to determine the relationship between brachial flow-mediated dilation (FMD) and carotid intima-media thickness (IMT) in a large multi-ethnic elderly cohort. BACKGROUND:Brachial flow-mediated dilation (FMD) is a physiologic measure and carotid IMT is an anatomic structural measure of...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.atherosclerosis.2007.07.032

    authors: Yeboah J,Burke GL,Crouse JR,Herrington DM

    更新日期:2008-04-01 00:00:00

  • Characterization of atherosclerosis in a patient with familial high-density lipoprotein deficiency.

    abstract::We describe the cardiovascular state of a 60-year-old homozygous patient with familial HDL deficiency (Tangier disease). The patient was examined by coronary angiography and intravascular ultrasound because of chest pain at rest and on exertion. We found a normal left ventricular function, moderately diffuse coronary ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(94)90205-4

    authors: Walter M,Kerber S,Fechtrup C,Seedorf U,Breithardt G,Assmann G

    更新日期:1994-10-01 00:00:00

  • Effect of pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, on hepatic cholesterol 7 alpha-hydroxylase, acyl-coenzyme A: cholesterol acyltransferase, and bile lipid secretion in the hamster with intact enterohepatic circulation.

    abstract::The effects of administration of pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, on hepatic cholesterol 7 alpha-hydroxylase and acyl-coenzyme A: cholesterol acyltransferase (ACAT) activities and bile lipid secretion were investigated in Syrian golden hamsters. Continuous administrat...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(94)90092-2

    authors: Hayashi K,Noshiro M,Kurushima H,Kuga Y,Nomura S,Ohkura Y,Ohtani H,Kurokawa J,Tanaka K,Yasunobu Y

    更新日期:1994-12-01 00:00:00

  • Comparative effects of polyunsaturated- to saturated fatty acid ratio versus polyunsaturated- and monounsaturated fatty acids to saturated fatty acid ratio on lipid metabolism in rats.

    abstract::This study examined the effects of various polyunsaturated fatty acid (PUFA, P)/saturated fatty acid (SFA, S) ratio versus PUFA + monounsaturated fatty acid (MUFA, M)/SFA ratio on lipid metabolism. The P/S ratio of dietary fat was fixed at a certain level (0.5, 1, 2, or 4, respectively) for each of four pairs of rat g...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(98)00236-6

    authors: Chang NW,Huang PC

    更新日期:1999-01-01 00:00:00

  • Sulforaphane inhibits endothelial lipase expression through NF-κB in endothelial cells.

    abstract:OBJECTIVE:Endothelial lipase (EL) is a new member of triacylglycerol lipase family that has been shown to decrease high-density lipoprotein (HDL) cholesterol levels leading to increased risk of atherosclerosis. Its expression is increased during inflammation and by inflammatory cytokines. Sulforaphane (SFN) is a natura...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2010.07.015

    authors: Kivelä AM,Mäkinen PI,Jyrkkänen HK,Mella-Aho E,Xia Y,Kansanen E,Leinonen H,Verma IM,Ylä-Herttuala S,Levonen AL

    更新日期:2010-11-01 00:00:00

  • Associations of plasma homocysteine and the methylenetetrahydrofolate reductase C677T polymorphism with carotid intima media thickness among South Asian, Chinese and European Canadians.

    abstract:BACKGROUND:Few studies have evaluated the associations of plasma homocysteine concentration, the methylenetetrahydrofolate reductase (MTHFR) C677T genotype and B vitamin concentration with intima media thickness (IMT) in multiethnic populations. METHODS:In the Study of Health Assessment and Risk in Ethnic groups (SHAR...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2004.06.003

    authors: Kelemen LE,Anand SS,Hegele RA,Stampfer MJ,Rosner B,Willett WC,Montague PA,Lonn E,Vuksan V,Teo KK,Devanesen S,Yusuf S

    更新日期:2004-10-01 00:00:00

  • Roles of Sp1 and protein kinase C in regulation of human serum paraoxonase 1 (PON1) gene transcription in HepG2 cells.

    abstract::Human serum paraoxonase 1 (PON1) is associated with high-density lipoprotein, and inhibits oxidative modification of low-density lipoprotein in vitro. Therefore, PON1 is supposed to protect against atherosclerosis in vivo. In this study, we investigated the direct effect of Sp1 on PON1 transcription in HepG2 cells usi...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2004.05.029

    authors: Osaki F,Ikeda Y,Suehiro T,Ota K,Tsuzura S,Arii K,Kumon Y,Hashimoto K

    更新日期:2004-10-01 00:00:00

  • Endothelial function and arterial stiffness indexes in subjects with acute ischemic stroke: Relationship with TOAST subtype.

    abstract:BACKGROUND AND AIMS:Only one study has examined endothelial function in subjects with acute ischemic stroke and no study has yet assessed arterial stiffness and reactive hyperemia peripheral arterial tonometry (RH-PAT) in ischemic stroke and its clinical subtypes. Our study aimed to evaluate arterial stiffness and endo...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2016.10.044

    authors: Tuttolomondo A,Casuccio A,Della Corte V,Maida C,Pecoraro R,Di Raimondo D,Vassallo V,Simonetta I,Arnao V,Pinto A

    更新日期:2017-01-01 00:00:00

  • Newly developed reconstituted high-density lipoprotein containing sphingosine-1-phosphate induces endothelial tube formation.

    abstract::Reconstituted high-density lipoprotein (rHDL) has been shown to produce a rapid regression of atherosclerosis in animal models and humans. Sphingosine-1-phosphate (S1P), which is a bioactive lipid in HDL, plays a role in mitogenesis, endothelial cell motility, and cell survival, as well as organization and differentia...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2006.10.020

    authors: Matsuo Y,Miura S,Kawamura A,Uehara Y,Rye KA,Saku K

    更新日期:2007-09-01 00:00:00

  • Intermittent claudication: an overview.

    abstract::Intermittent claudication (IC) is defined by leg muscle pain, cramping and fatigue brought on by ambulation/exercise; relieved on rest; and caused by inadequate blood supply and is the primary symptom of peripheral arterial disease (PAD). PAD has a detrimental effect on the quality of life. PAD is a debilitating ather...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,评审

    doi:10.1016/j.atherosclerosis.2005.11.027

    authors: Meru AV,Mittra S,Thyagarajan B,Chugh A

    更新日期:2006-08-01 00:00:00

  • Levels of plasma factor VII and factor VII activated forms as a function of plasma triglyceride levels.

    abstract::It has been shown that triglyceride levels are one of the determinants of factor VII levels. In this study we have simultaneously evaluated, in a group of 102 healthy individuals, the different forms of factor VII, namely factor VII mass, factor VII coagulant activity, activated factor VII double-chain form and factor...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(93)90050-5

    authors: Negri M,Arigliano PL,Talamini G,Carlini S,Manzato F,Bonadonna G

    更新日期:1993-02-01 00:00:00

  • Analysis of secretory group II phospholipase A2 expression in human aortic tissue in dependence on the degree of atherosclerosis.

    abstract::Secretory non-pancreatic (group II) phospholipase A2 (sPLA2) releases precursors of important mediators of inflammation from phospholipids. Based on the inflammatory character of atherosclerosis we previously described the identification of sPLA2 in human atherosclerotic plaques. In vitro studies on lipoproteins have ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(99)00045-3

    authors: Schiering A,Menschikowski M,Mueller E,Jaross W

    更新日期:1999-05-01 00:00:00

  • 7-ketocholesteryl-9-carboxynonanoate enhances ATP binding cassette transporter A1 expression mediated by PPARγ in THP-1 macrophages.

    abstract:BACKGROUND:ATP binding cassette transporter A1 (ABCA1) is a member of the ATP-binding cassette transporter family. It plays an essential role in mediating the efflux of excess cholesterol. It is known that peroxisome proliferator-activated receptor gamma (PPARγ) promoted ABCA1 expression. We previously found 7-ketochol...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2014.01.052

    authors: Chi Y,Wang L,Liu Y,Ma Y,Wang R,Han X,Qiao H,Lin J,Matsuura E,Liu S,Liu Q

    更新日期:2014-06-01 00:00:00

  • The relation of leptin and insulin with obesity-related cardiovascular risk factors in US adults.

    abstract::Previous studies of leptin with cardiovascular disease (CVD) risk factors have been limited by clinical samples or lack of representation of the general population. This cross-sectional study, designed to examine whether leptin or insulin may mediate the endogenous relation of obesity with metabolic, inflammatory, and...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2007.11.015

    authors: Reis JP,Macera CA,Wingard DL,Araneta MR,Lindsay SP,Marshall SJ

    更新日期:2008-09-01 00:00:00

  • Ciprofibrate in the therapy of type II hypercholesterolemia. A double-blind trial.

    abstract::The hypolipidemic efficacy of ciprofibrate was evaluated in patients with type II hypercholesterolemia. Patients were randomized to placebo or ciprofibrate (50 mg or 100 mg/day) and, after a 6-week baseline period, received medication for a period of 12 weeks. Blood samples were analyzed every 2 weeks. Twenty patients...

    journal_title:Atherosclerosis

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0021-9150(82)90115-0

    authors: Illingworth DR,Olsen GD,Cook SF,Sexton GJ,Wendel HA,Connor WE

    更新日期:1982-08-01 00:00:00

  • Expression and regulation of 12/15-lipoxygenases in human primary macrophages.

    abstract:OBJECTIVES:Atherosclerosis is a chronic disease characterized by two main features, lipid retention and inflammation. The 12/15-lipoxygenases play a two-faced role in atherosclerosis with pro-inflammatory effects through oxidation of LDL and anti-inflammatory effects through lipid mediator synthesis. In cells involved ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2012.07.022

    authors: Wuest SJ,Crucet M,Gemperle C,Loretz C,Hersberger M

    更新日期:2012-11-01 00:00:00

  • Impact of oxidized low density lipoprotein on vascular cells.

    abstract::Oxidized LDL (OxLDL) is a proatherogenic lipoprotein, accumulating in the vascular wall and contributing to the pathogenesis of vascular dysfunction early in the development of atherosclerosis. Enhanced serum levels of OxLDL, as well as antibodies against its epitopes, are predictive for endothelial dysfunction and co...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,评审

    doi:10.1016/j.atherosclerosis.2005.10.005

    authors: Galle J,Hansen-Hagge T,Wanner C,Seibold S

    更新日期:2006-04-01 00:00:00

  • Cholesterol vehicle in experimental atherosclerosis. Part 15. Randomized butter and randomized lard.

    abstract::Randomized lard and butter oil were conpared with native lard and butter oil for their effects on cholesterol-induced atherosclerosis in rabbits. In each experiment there was also a group fed corn oil. The diets contained 2% cholesterol and 6% fat and were fed for eight weeks. Randomization of either butter or lard ha...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(77)90043-0

    authors: Kritchevsky D,Tepper SA

    更新日期:1977-07-01 00:00:00

  • Inflammatory and metabolic mechanisms underlying the calcific aortic valve disease.

    abstract::Although calcific aortic stenosis is a very common disease with major adverse cardiovascular events and healthcare costs, there are no effective medical interventions to delay or halt its progression. Cardiometabolic risk factors, including smoking and male sex, are linked to aortic stenosis. Emerging studies have ide...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,评审

    doi:10.1016/j.atherosclerosis.2018.08.029

    authors: Cho KI,Sakuma I,Sohn IS,Jo SH,Koh KK

    更新日期:2018-10-01 00:00:00

  • Associations of physical activity and sedentary time with lipoprotein subclasses in Norwegian schoolchildren: The Active Smarter Kids (ASK) study.

    abstract:BACKGROUND AND AIMS:Physical activity is favourably associated with certain markers of lipid metabolism. The relationship of physical activity with lipoprotein particle profiles in children is not known. Here we examine cross-sectional associations between objectively measured physical activity and sedentary time with ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2019.05.023

    authors: Jones PR,Rajalahti T,Resaland GK,Aadland E,Steene-Johannessen J,Anderssen SA,Bathen TF,Andreassen T,Kvalheim OM,Ekelund U

    更新日期:2019-09-01 00:00:00

  • The relationship between cholesteryl ester transfer protein levels and risk factor profile in patients with familial hypercholesterolemia.

    abstract:BACKGROUND:Cholesteryl ester transfer protein (CETP) mediates the transfer of neutral lipids between lipoproteins. The role of CETP in atherogenesis is controversial. To better understand the relationships between plasma CETP levels, lipoproteins and atherosclerosis, we assessed these parameters in patients with an enh...

    journal_title:Atherosclerosis

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.atherosclerosis.2003.11.020

    authors: de Grooth GJ,Smilde TJ,Van Wissen S,Klerkx AH,Zwinderman AH,Fruchart JC,Kastelein JJ,Stalenhoef AF,Kuivenhoven JA

    更新日期:2004-04-01 00:00:00

  • A year-long study of changes induced by thyroidectomy in the plasma lipid and lipoprotein spectrum in the European badger.

    abstract::Hypothyroidism is associated with hypercholesterolemia and increased risk for atherosclerotic disease. The European badger exhibits large seasonal changes in thyroid activity and the annual minimum of plasma thyroxine level in this species occurs at the same period of the year (i.e. late fall) as a pronounced hypercho...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(84)90190-4

    authors: Laplaud PM,Beaubatie L,Maurel D,Catanzano G

    更新日期:1984-11-01 00:00:00