VEGF-A-induced chemotaxis of CD16+ monocytes is decreased secondary to lower VEGFR-1 expression.

abstract：OBJECTIVE:To identify the prevalence and predictors of lipid abnormalities in statin-treated patients in the UK. METHODS:A retrospective cohort study was performed using the UK General Practice Research Database. Patients >or=35 years of age were included if they received first-ever statin between January 2000 and Dec...

journal_title：Atherosclerosis

authors： Phatak H,Wentworth C,Sazonov V,Burke T

更新日期：2009-01-01 00:00:00

abstract：:Low density lipoprotein (LDL) and high density lipoprotein (HDL3) were tested for their ability to induce inositol phospholipid turnover and inositol phosphate production in bovine aortic endothelial cells (BAEC). The production of inositol phosphates following hydrolysis of the phosphoinositides was demonstrated by t...

journal_title：Atherosclerosis

authors： Myers DE,Fidge NH,Stanton H,Larkins RG

更新日期：1992-01-01 00:00:00

abstract：:The changes that occur with age in the distribution of atherosclerotic lesions around arterial branch points challenge accepted theories relating disease to haemodynamic stresses. We investigated whether flow near branch points changes with age in a way that can account for the different lesion distributions. Flow aro...

journal_title：Atherosclerosis

authors： Al-Musawi SL,Bishton J,Dean J,Williams S,Cremers SG,Weinberg PD

更新日期：2004-01-01 00:00:00

abstract：:Essential polyunsaturated fatty acids (PUFA) of the omega-3 family are believed to protect against cardiovascular disease. A rich source of omega-3 PUFA is found in fish and marine mammals (seal, walrus, whale), which are a large part of the traditional diet of Alaska Natives (Eskimo, American Indians, Aleuts), a grou...

journal_title：Atherosclerosis

authors： McLaughlin J,Middaugh J,Boudreau D,Malcom G,Parry S,Tracy R,Newman W

更新日期：2005-08-01 00:00:00

abstract：:Methodological differences and variations in health care regulations among countries often preclude direct comparisons of cost-effectiveness studies. A projected risk model was applied, designed to determine the economic value in the United States of pravastatin in the secondary prevention of coronary heart disease (C...

journal_title：Atherosclerosis

authors： Muls E,Van Ganse E,Closon MC

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:Low levels of high density lipoprotein-cholesterol (HDL-C) are highly prevalent in subjects presenting premature atherosclerosis. It is indeterminate as to whether high cardiovascular risk in low HDL-C subjects occurs concomitantly with elevated oxidative stress and/or with biologically dysfunctional HDL part...

journal_title：Atherosclerosis

authors： Kontush A,de Faria EC,Chantepie S,Chapman MJ

更新日期：2005-10-01 00:00:00

abstract：:Sixty-two subjects from 23 families were evaluated by serum lipid analyses and tissue culture biochemistry in skin fibroblasts. In 53 cases from 19 families with proven familial hypercholesterolemia (FHC), fibroblast cultures were successful. In 45 of these cases (85%) the clinical diagnosis of hyper- or normocholeste...

journal_title：Atherosclerosis

authors： Keller C,Harders-Spengel K,Spengel F,Wieczorek A,Wolfram G,Zöllner N

更新日期：1981-04-01 00:00:00

abstract：OBJECTIVE:Plaque with dense inflammatory cells, including macrophages, thin fibrous cap and superficial necrotic/lipid core is thought to be prone-to-rupture. We report a time-resolved laser-induced fluorescence spectroscopy (TR-LIFS) technique for detection of such markers of plaque vulnerability in human plaques. ME...

journal_title：Atherosclerosis

authors： Marcu L,Jo JA,Fang Q,Papaioannou T,Reil T,Qiao JH,Baker JD,Freischlag JA,Fishbein MC

更新日期：2009-05-01 00:00:00

abstract：:Oscillatory shear stress applied to the lining of blood vessels causes endothelial cell injury, one of the essential postulated prerequisites to the development of atherosclerosis. The purpose of this investigation was to study effects of shear stress on bovine aortic endothelial cells (BAEC), in vitro, for varying le...

journal_title：Atherosclerosis

authors： Skarlatos SI,Hollis TM

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVE:Common variants at the 2q36.3-IRS1 locus are associated with insulin resistance (IR), type 2 diabetes (T2D) and coronary artery disease (CAD) in large-scale association studies. We tested the hypothesis that variants at this locus are associated with subclinical atherosclerosis traits. METHODS:We studied 274...

journal_title：Atherosclerosis

authors： Lim S,Hong J,Liu CT,Hivert MF,White CC,Murabito JM,O'Donnell CJ,Dupuis J,Florez JC,Meigs JB

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:Adherence to a Mediterranean-style diet (MeDi) may protect against clinical vascular events by reducing atherosclerosis, but data is limited. This is the first observational study of the association between MeDi adherence and carotid plaque thickness and area. METHODS:The study included 1374 participants of ...

journal_title：Atherosclerosis

authors： Gardener H,Wright CB,Cabral D,Scarmeas N,Gu Y,Cheung K,Elkind MS,Sacco RL,Rundek T

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Abdominal aortic aneurysms (AAA) is a chronic inflammatory disease in which signal transducer and activator of transcription 3 (STAT3), and disintegrin and metalloproteinase 17 (ADAM17) play important roles. However, it remains unclear whether ursolic acid (UA), a natural pentacyclic triterpenoid ca...

journal_title：Atherosclerosis

authors： Zhai M,Guo J,Ma H,Shi W,Jou D,Yan D,Liu T,Tao J,Duan J,Wang Y,Li S,Lv J,Li C,Lin J,Zhang C,Lin L

更新日期：2018-04-01 00:00:00

abstract：:Dietary linoleate was effective to increase LDL fluidity in adult men but did not significantly influence VLDL or HDL fluidities. Lipoproteins were isolated ultracentrifugally from plasma of sixteen healthy, free living male volunteers consuming controlled diets formulated from typical U.S.A. foods to have 35 energy %...

journal_title：Atherosclerosis

authors： Berlin E,Judd JT,Marshall MW,Kliman PG

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The association between cholesterol and stroke has been inconsistent. This study aimed to examine the association between total cholesterol (TC) and mortality from total stroke and stroke subtypes. METHODS:503,340 Korean adults aged 40-80 years without a history of heart disease or stroke participa...

journal_title：Atherosclerosis

authors： Yi SW,Shin DH,Kim H,Yi JJ,Ohrr H

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Exercise training (ET) helps treat atherosclerosis. However, many patients stop regular ET for various reasons. The effect of detraining on atherosclerosis is not well studied. We examined the effects of ET vs. short-term detraining on atheromatous matrix-metalloproteinase (MMP) activity in preexist...

journal_title：Atherosclerosis

authors： Kim J,Jang HJ,Schellingerhout D,Kang JW,Choi S,Oh H,Kim EJ,Lee SK,Lee JS,Kwon IC,Kim K,Koh YJ,Ryu WS,Kim DE

更新日期：2020-04-01 00:00:00

abstract：:The proband is a 50 year-old woman born from a consanguineous marriage. She has been suffering from angina pectoris since the age of 38 and underwent coronary bypass surgery for three-vessel disease at 48. The presence of low plasma levels of total cholesterol and high density lipoprotein (HDL) cholesterol (2.4 and 0....

journal_title：Atherosclerosis

authors： Bertolini S,Pisciotta L,Seri M,Cusano R,Cantafora A,Calabresi L,Franceschini G,Ravazzolo R,Calandra S

更新日期：2001-02-15 00:00:00

abstract：OBJECTIVE:Sarcopenia of legs is an important cause of physical dysfunctions, frailty and dependence. Many predisposing and underlying mechanisms of sarcopenia, including age, sedentary life style, oxidative stress, insulin resistance, and low testosterone levels, are also known to be related to atherosclerosis, which i...

journal_title：Atherosclerosis

authors： Ochi M,Kohara K,Tabara Y,Kido T,Uetani E,Ochi N,Igase M,Miki T

更新日期：2010-09-01 00:00:00

abstract：:To test the hypothesis of altered energy production in aortic sites predisposed to lesion formation, both coupled oxidative phosphorylation (evaluated from P/O ratios) and control of the energy-linked (ATP) NADH transhydrogenase were examined in muscular cushions at the celiac artery bifurcation. Comparisons were made...

journal_title：Atherosclerosis

authors： Hajjar DP,Smith SC

更新日期：1980-06-01 00:00:00

abstract：:The effects of atorvastatin (Lipitor) were evaluated in 40 patients with familial hypercholesterolemia (FH). Following a 6 week drug-free baseline period 20 male and 20 female patients were treated with atorvastatin 40 mg once daily (QD) for the initial 6 weeks increasing to 80 mg QD during the following 6 weeks. Ator...

journal_title：Atherosclerosis

authors： Hoogerbrugge N,Jansen H

更新日期：1999-09-01 00:00:00

abstract：:To investigate the association between time from diagnosis of type 2 diabetes to initiation of insulin therapy (pre-exogenous insulin period) and intima-media thickness (IMT) of the common carotid artery (CCA), a cross-sectional analysis was conducted among 98 males and 193 females (90% Hispanic) with type 2 diabetes,...

journal_title：Atherosclerosis

authors： Zheng L,Buchanan TA,Hodis HN,Li Y,Torres M,Mack WJ

更新日期：2003-10-01 00:00:00

abstract：:This study was undertaken to determine whether sialic acid removal alters the catabolism of low density lipoprotein in humans. Human low density lipoproteins labeled in vitro with 125I were incubated in the presence (termed desialylated) or absence (sialylated) of neuraminidase. The treatment with neuraminidase from C...

journal_title：Atherosclerosis

authors： Malmendier CL,Delcroix C,Fontaine M

更新日期：1980-10-01 00:00:00

abstract：:Blood serum of most patients with coronary heart disease (CHD) caused a 2-5-fold increase in the total cholesterol content of smooth muscle cells cultured from unaffected human aortic intima, i.e. possessed an atherogenic potential manifested in culture. Removal of immunoglobulins G and M from an atherogenic serum bro...

journal_title：Atherosclerosis

authors： Tertov VV,Orekhov AN,Sayadyan KS,Serebrennikov SG,Kacharava AG,Lyakishev AA,Smirnov VN

更新日期：1990-04-01 00:00:00

abstract：:The effects of the artificial triglyceride-phospholipid emulsion (10% intralipid) on HDL subfraction were studied in vivo. After a 14-h fast, subjects received intralipid via a 4-h infusion. Serum lipoproteins were analyzed before and at 4 and 6 h after the start of the infusion. At 4-h the following acute changes by ...

journal_title：Atherosclerosis

authors： Sakuma N,Lin C,Matsumoto Y,Ikeuchi R,Ichikawa T,Hirata H,Noguchi Y,Fujinami T

更新日期：1988-11-01 00:00:00

abstract：:We have examined the prevalence of clinically significant atherosclerosis in 78 patients with type III hyperlipoproteinemia (HLP) and homozygosity for apolipoprotein (apo) E2. Forty-six of these individuals (59%) had no atherosclerosis, 32 patients (41%) had atherosclerosis, i.e., atherosclerosis of the extracranial c...

journal_title：Atherosclerosis

authors： Dobmeyer J,Lohrmann J,Feussner G

更新日期：1996-01-05 00:00:00

abstract：:High-density lipoprotein (HDL) cholesteryl esters (CE) are taken up by many cells without parallel uptake of HDL apolipoproteins. This selective uptake of HDL CE was investigated in human monocyte-derived macrophages (HMM). HDL3 (d = 1.125-1.21 g/ml) was labeled in its apolipoprotein A-I moiety with 125I and in its CE...

journal_title：Atherosclerosis

authors： Rinninger F,Deichen JT,Jäckle S,Windler E,Greten H

更新日期：1994-02-01 00:00:00

abstract：:Evidence suggests low vitamin D and elevated parathyroid hormone (PTH) concentrations may increase risk for cardiovascular disease. However, little is known about the association between vitamin D or PTH and subclinical atherosclerosis. This cross-sectional study included 654 community-dwelling older adults aged 55-96...

journal_title：Atherosclerosis

authors： Reis JP,von Mühlen D,Michos ED,Miller ER 3rd,Appel LJ,Araneta MR,Barrett-Connor E

更新日期：2009-12-01 00:00:00

abstract：:The effects of chronic renal failure (CRF) and corticosteroid treatment on the aortic uptake of labelled free and esterified cholesterol (FC and EC) were investigated in normocholesterolemic rabbits. Methylprednisolone, 0.4 mg/day, or placebo was administered for 14 weeks to rabbits with normal renal function and with...

journal_title：Atherosclerosis

authors： Tvedegaard E,Szpirt W,Nielsen M

更新日期：1983-05-01 00:00:00

abstract：:The association between serum selenium concentration and a number of coronary heart disease risk factors is studied in 364 males from southern Italy participating in the Olivetti Heart Study. Selenium correlates positively and significantly with serum cholesterol (r = 0.120; P = 0.022), and this positive association p...

journal_title：Atherosclerosis

authors： Jossa F,Trevisan M,Krogh V,Farinaro E,Giumetti D,Fusco G,Galasso R,Panico S,Frascatore S,Mellone C

更新日期：1991-04-01 00:00:00

abstract：:In the French Canadian population six mutations appear to be responsible for about 85% of FH cases. Two of these mutations are large deletions. The most prevalent deletion is a >15 kb deletion of the promoter and first exon; the second, a 5 kb deletion that removes exons 2 and 3. The high frequency of these deletions ...

journal_title：Atherosclerosis

authors： Bernier L,Boulet L,Roy M,Dufour R,Larivière F,Davignon J

更新日期：2008-03-01 00:00:00

abstract：:Inflammation has been demonstrated to be an important risk factor for the development of cardiovascular events. Patients with elevated white blood cell counts have been shown to be in a higher risk of developing acute myocardial infarction and acute coronary and vascular events. We review the clinical data of high whi...

journal_title：Atherosclerosis

authors： Hoffman M,Blum A,Baruch R,Kaplan E,Benjamin M

更新日期：2004-01-01 00:00:00