Correlation between cholesterol content in circulating immune complexes and atherogenic properties of CHD patients' serum manifested in cell culture.

abstract：UNLABELLED:In the last few years it has been proved that risk factors for atherosclerosis are present in children and adolescents, and that already at this early age they are connected with anatomic, atheromatous changes in vessels. These changes can not be fully explained as occurring in young people exhibiting tradit...

journal_title：Atherosclerosis

authors： Glowinska B,Urban M,Koput A,Galar M

更新日期：2003-04-01 00:00:00

abstract：:In type 2 diabetics, the progression of atherosclerosis is more rapid than the general population and 80% of these patients will die of an atherosclerotic event. Since in these patients hyperglycemia per se confers increased risk for cardiovascular disease (CVD), the presence of even borderline-high-risk LDL-C signals...

journal_title：Atherosclerosis

authors： Baliarsingh S,Beg ZH,Ahmad J

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVES:Markers of non-specific inflammation, such as C-reactive protein (CRP) or leukocyte count are increased in end-stage renal disease patients. Recent studies have shown positive associations between inflammatory markers and cardiovascular mortality in kidney transplant recipients, but these analyses had been l...

journal_title：Atherosclerosis

authors： Krüger B,Walberer A,Debler J,Böger CA,Farkas S,Reinhold SW,Obed A,Schlitt HJ,Fischereder M,Banas B,Krämer BK

更新日期：2010-06-01 00:00:00

abstract：:In a sample taken from the genetically isolated Alberta Hutterites, we previously found that PON1 variation was associated with variation in plasma lipoprotein traits, including LDL and HDL cholesterol. With the recent cloning of the PON1-related gene PON2, we undertook studies of the association between genetic varia...

journal_title：Atherosclerosis

authors： Boright AP,Connelly PW,Brunt JH,Scherer SW,Tsui LC,Hegele RA

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Diabetic patients are at high risk of stroke and coronary artery disease. Recent data suggest that arachidonic acid metabolism is altered in diabetic conditions and that these alterations contribute to accelerated atherosclerosis. Little is known about how these alterations affect the metabolism and...

journal_title：Atherosclerosis

authors： Ménégaut L,Masson D,Abello N,Denimal D,Truntzer C,Ducoroy P,Lagrost L,Pais de Barros JP,Athias A,Petit JM,Martin L,Steinmetz E,Kretz B

更新日期：2016-08-01 00:00:00

abstract：:Angiotensin II plays an important role in diastolic heart failure (DHF). However, genetic studies of DHF are scarce in the literature. We hypothesized that RAS genes might be the susceptible genes for DHF and conducted a propensity score-based case-control study to prove this hypothesis. A total of 666 subjects (285 d...

journal_title：Atherosclerosis

authors： Wu CK,Luo JL,Wu XM,Tsai CT,Lin JW,Hwang JJ,Lin JL,Tseng CD,Chiang FT

更新日期：2009-08-01 00:00:00

abstract：:SR-12813 inhibits cholesterol biosynthesis in Hep G2 cells via an enhanced degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Here we also show that SR-12813 inhibits cholesterol biosynthesis in vivo. A sterol balance study was performed in normolipemic beagle dogs. The dogs were given SR-12813 ...

journal_title：Atherosclerosis

authors： Berkhout TA,Simon HM,Jackson B,Yates J,Pearce N,Groot PH,Bentzen C,Niesor E,Kerns WD,Suckling KE

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Aortic atherosclerosis is an aggregate marker of vascular risk factor exposure and has been associated with intracranial atherosclerosis and stroke. We hypothesized that atherosclerosis of the descending aorta (DAo) could be a risk marker for brain aging and injury. METHODS:We evaluated 1527 partic...

journal_title：Atherosclerosis

authors： Aparicio HJ,Petrea RE,Massaro JM,Manning WJ,Oyama-Manabe N,Beiser AS,Kase CS,D'Agostino RB,Wolf PA,Vasan RS,DeCarli C,O'Donnell CJ,Seshadri S

更新日期：2017-10-01 00:00:00

abstract：:The possible role of four candidate genes in lipid and lipoprotein response to diet was examined in 214 members of two large kibbutz settlements in Israel. Four site polymorphisms (signal peptide insertion/deletion, XbaI, EcoRI and MspI) of the apo B gene, the common apo E genotypes, three common mutations (T-93G, S44...

journal_title：Atherosclerosis

authors： Friedlander Y,Leitersdorf E,Vecsler R,Funke H,Kark J

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Type 2 diabetes (DM2) and impaired glucose metabolism (IGM) are associated with an increased cardiovascular disease risk. Impaired endothelial synthesis of nitric oxide (NO) is an important feature of atherothrombosis and can be estimated from endothelium-dependent flow-mediated dilation (FMD). It is controv...

journal_title：Atherosclerosis

authors： Henry RM,Ferreira I,Kostense PJ,Dekker JM,Nijpels G,Heine RJ,Kamp O,Bouter LM,Stehouwer CD

更新日期：2004-05-01 00:00:00

abstract：:Oxidation of low density lipoproteins (LDL) is considered a key event in the pathogenesis of atherosclerotic lesions. Disturbed generation of coagulatory and anticoagulatory factors by endothelial cells contributes to thrombosis and the progression of atherosclerosis in coronary arteries. In this study, the effects of...

journal_title：Atherosclerosis

authors： Gräfe M,Auch-Schwelk W,Hertel H,Terbeek D,Steinheider G,Loebe M,Fleck E

更新日期：1998-03-01 00:00:00

abstract：:To assess the risk for homocyst(e)ine-associated vascular disease, overt hyperhomocyst(e)inemia should be demonstrated. In nonhomocystinuric subjects, clinical vascular disease must have developed after 40 or more years of persistent hyperhomocyst(e)inemia which may not be present without a genetic defect(s). Nongenet...

journal_title：Atherosclerosis

authors： Kang SS,Wong PW

更新日期：1996-01-26 00:00:00

abstract：:Experiments were performed on thoracic aortae of 12 male Sprague-Dawley [corrected] rats to determine the statistical frequency of isolated leaks to Evans blue-albumin (EBA) conjugate at the level of individual cells and to assess the relationship of such leaks to the cell turnover process. Fluorescence microscopy was...

journal_title：Atherosclerosis

authors： Lin SJ,Jan KM,Schuessler G,Weinbaum S,Chien S

更新日期：1988-10-01 00:00:00

abstract：OBJECTIVES:This study tests the validity of the Hattori formula to calculate LDL apoB based on plasma lipids and total apoB. METHODS:In 2178 patients in a tertiary care lipid clinic, LDL apoB calculated as suggested by Hattori et al. was compared to directly measured LDL apoB isolated by ultracentrifugation. RESULTS:...

journal_title：Atherosclerosis

authors： Sniderman AD,Tremblay AJ,De Graaf J,Couture P

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:Currently no data exists regarding the outcomes after the novel endothelial progenitor cell capturing stent (EPCcS) placement in bifurcation lesions using a provisional T-stenting. This study evaluates the 1-year clinical outcome in patients treated with the EPCcS for a bifurcation lesion using a provisional ...

journal_title：Atherosclerosis

authors： Beijk MA,Klomp M,Koch KT,Henriques JP,Vis MM,Baan J Jr,Tijssen JG,Piek JJ,de Winter RJ

更新日期：2010-12-01 00:00:00

abstract：:Lipoprotein-associated phospholipase A2 (Lp-PLA2) generates pro-inflammatory molecules from oxidized LDL. We examined the association between Lp-PLA2 plasma concentrations and risk of stable coronary artery disease (CAD) in a large case-control study and further assessed the relationship between Lp-PLA2 and various li...

journal_title：Atherosclerosis

authors： Khuseyinova N,Imhof A,Rothenbacher D,Trischler G,Kuelb S,Scharnagl H,Maerz W,Brenner H,Koenig W

更新日期：2005-09-01 00:00:00

abstract：:Fractional esterification rate of cholesterol in high density lipoprotein (HDL) (FER[HDL]) can predict the size distribution and physicochemical characteristics of HDL in plasma. In the present study, we investigated the correlation of FER(HDL) with the particle size of low density lipoprotein (LDL) (LDL-size) in 111 ...

journal_title：Atherosclerosis

authors： Ohta T,Saku K,Takata K,Nagata N,Maung KK,Matsuda I

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:In Europeans, 45 genetic risk variants for coronary artery disease (CAD) have been identified in genome-wide association studies. We constructed a genetic risk score (GRS) of these variants to estimate the effect on incidence and clinical predictability of myocardial infarction (MI) and CAD. METHODS:Genotyp...

journal_title：Atherosclerosis

authors： Krarup NT,Borglykke A,Allin KH,Sandholt CH,Justesen JM,Andersson EA,Grarup N,Jørgensen T,Pedersen O,Hansen T

更新日期：2015-06-01 00:00:00

abstract：:To test the hypothesis of altered energy production in aortic sites predisposed to lesion formation, both coupled oxidative phosphorylation (evaluated from P/O ratios) and control of the energy-linked (ATP) NADH transhydrogenase were examined in muscular cushions at the celiac artery bifurcation. Comparisons were made...

journal_title：Atherosclerosis

authors： Hajjar DP,Smith SC

更新日期：1980-06-01 00:00:00

abstract：OBJECTIVE:Perivascular fat through the secretion of paracrine and pro-inflammatory mediators may play a role in obesity-mediated vascular disease. We sought to examine associations between adipose tissue depots immediately surrounding the thoracic aorta, metabolic risk factors, and vascular calcification. METHODS:In p...

journal_title：Atherosclerosis

authors： Lehman SJ,Massaro JM,Schlett CL,O'Donnell CJ,Hoffmann U,Fox CS

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Vascular calcification is a common finding in abdominal aortic aneurysms (AAA) however whether it predicts aneurysm expansion is controversial. OBJECTIVES:1) To establish a reproducible method of assessing AAA calcification using computed tomography (CT); 2) To investigate the association between AAA calcif...

journal_title：Atherosclerosis

authors： Hendy K,Gunnarsson R,Cronin O,Golledge J

更新日期：2015-11-01 00:00:00

abstract：:Mild hyperhomocysteinemia is considered an important risk factor for vascular disease. A common polymorphism (677C-->T) in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with a decreased enzyme activity and consequent higher circulating levels of homocysteine. We hypothesized that the serum levels ...

journal_title：Atherosclerosis

authors： Pisciotta L,Cortese C,Gnasso A,Liberatoscioli L,Pastore A,Mannucci L,Irace C,Federici G,Bertolini S

更新日期：2005-04-01 00:00:00

abstract：:The number of low density platelets was found to be increased in patients with hypercholesterolemia, as compared with the number in controls. The percentage increase of the low density platelet subpopulation was even more pronounced in patients with hypercholesterolemia when compared with that in patients suffering fr...

journal_title：Atherosclerosis

authors： Opper C,Clement C,Schwarz H,Krappe J,Steinmetz A,Schneider J,Wesemann W

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) have been linked with an increased risk of type 2 diabetes, but their relationships with cardiovascular disease (CVD) are uncertain. We aimed to assess the associations of ALT and AST with CVD risk and determine their potential utility for C...

journal_title：Atherosclerosis

authors： Kunutsor SK,Bakker SJ,Kootstra-Ros JE,Blokzijl H,Gansevoort RT,Dullaart RP

更新日期：2015-11-01 00:00:00

abstract：:Accelerated coronary atherosclerosis is a major risk limiting long-term survival after heart transplantation and is commonly associated with dyslipoproteinemia even in subjects who were not dyslipoproteinemic before intervention. The purpose of this study was to analyse the abnormalities in the lipid profiles of 2 dif...

journal_title：Atherosclerosis

authors： Atger V,Cambillau M,Guillemain R,Farge D,Dreyfus G,Hamon S,Girard A,Carpentier A,Moatti N

更新日期：1990-03-01 00:00:00

abstract：:A chondroitin sulfate-dermatan sulfate proteoglycan was isolated from bovine aorta intima by extraction of the tissue with 4 M guanidine hydrochloride. The proteoglycan was purified by CsCl isopycnic centrifugation followed by gel filtration and ion exchange chromatography. A monoclonal antibody C8F4 was developed to ...

journal_title：Atherosclerosis

authors： Radhakrishnamurthy B,Jeansonne N,Tracy RE,Berenson GS

更新日期：1993-01-25 00:00:00

abstract：:HMG-CoA reductase inhibitor drugs or 'statins' have been shown to effectively reduce plasma total cholesterol (CHOL), CHOL associated with low-density-lipoprotein (LDL), and triglycerides (TG). In addition, slight elevations in HDL-CHOL are also typically observed. Poloxamer 407 (P-407), a nonionic surfactant, effecti...

journal_title：Atherosclerosis

authors： Johnston TP,Baker JC,Hall D,Jamal S,Palmer WK,Emeson EE

更新日期：2000-04-01 00:00:00

abstract：:The effect of different fat loads on postprandial lipemia and hemostatic activity was examined in 10 middle-aged men using 3 different meals. One meal was rich in saturated fatty acids (cream), the other rich in n-6 polyunsaturated fatty acids (sunflower oil) and the third was fat-free containing only carbohydrates. L...

journal_title：Atherosclerosis

authors： Salomaa V,Rasi V,Pekkanen J,Jauhiainen M,Vahtera E,Pietinen P,Korhonen H,Kuulasmaa K,Ehnholm C

更新日期：1993-10-01 00:00:00

abstract：:The ultrastructure of the aortic intima and serum lipid levels in Fischer 344 rats were examined at the ages of 12, 18 and 24 months after feeding the animals an atherogenic diet (2% cholesterol, 0.25% sodium cholate, 5% beef fat) for 6 months. Structural changes in the intima were noticeable only at the age of 24 mon...

journal_title：Atherosclerosis

authors： Nakamura H,Izumiyama N,Nakamura K,Ohtsubo K

更新日期：1989-10-01 00:00:00

abstract：:Self-administration of anabolic-androgenic steroids to increase muscular strength and lean body mass has been used widely among athletes. Flow mediated dilatation (FMD) determined by ultrasound of the brachial artery is accepted as both an in vivo index of endothelial function and an indicator for future atheroscleros...

journal_title：Atherosclerosis

authors： Ebenbichler CF,Sturm W,Gänzer H,Bodner J,Mangweth B,Ritsch A,Sandhofer A,Lechleitner M,Föger B,Patsch JR

更新日期：2001-10-01 00:00:00