Binding properties of circulating Evans blue in rabbits as determined by disc electrophoresis.

abstract：OBJECTIVE:The association of high-density lipoprotein particle (HDL-P) with atherosclerosis may be stronger than that of HDL-cholesterol (HDL-C) and independent of conventional cardiovascular risk factors. Whether associations persist in populations at low risk of coronary heart disease (CHD) remains unclear. This stud...

journal_title：Atherosclerosis

authors： Zaid M,Fujiyoshi A,Miura K,Abbott RD,Okamura T,Takashima N,Torii S,Saito Y,Hisamatsu T,Miyagawa N,Ohkubo T,Kadota A,Sekikawa A,Maegawa H,Nakamura Y,Mitsunami K,Ueshima H,SESSA Research group.

更新日期：2015-04-01 00:00:00

abstract：AIMS:Besides carotid or cardiac embolism, stroke can occur via microangiopathy (small arterial disease [SAD]) and macroangiopathy (intracranial atherosclerotic stroke [ICAS]) of the intracranial vasculature. There have been efforts to identify risk factors specific to microangiopathy and macroangiopathy, including vasc...

journal_title：Atherosclerosis

authors： Bang OY,Chung JW,Ryoo S,Moon GJ,Kim GM,Chung CS,Lee KH

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:Deletion of inducible nitric oxide synthase (iNOS) in apolipoprotein E knockout mice was shown to mitigate the extent of arteriosclerosis. Oxidized low density lipoprotein (oxLDL) inhibits macrophage migration and traps foam cells, possibly through a mechanism involving oxidative stress. Here, we addressed wh...

journal_title：Atherosclerosis

authors： Huang H,Koelle P,Fendler M,Schröttle A,Czihal M,Hoffmann U,Conrad M,Kuhlencordt PJ

更新日期：2014-07-01 00:00:00

abstract：:Although triglycerides (TG) are a major risk factor for coronary artery disease (CAD), their exact role is still controversial. Recently, a T/C polymorphism in the promoter region of the apoA5 gene at position 1131 has been found that is associated with an increased plasma TG concentration. We investigated the role of...

journal_title：Atherosclerosis

authors： Szalai C,Keszei M,Duba J,Prohászka Z,Kozma GT,Császár A,Balogh S,Almássy Z,Fust G,Czinner A

更新日期：2004-03-01 00:00:00

abstract：:The presence of Chlamydia pneumoniae in the human arterial system has mainly been determined in atherosclerotic plaque, whereas the adventitia has remained relatively unexplored. We assessed the presence of C. pneumoniae in all three vessel wall layers of coronary (n=72) and brachial (n=48) arteries in relation to loc...

journal_title：Atherosclerosis

authors： Vink A,Pasterkamp G,Poppen M,Schoneveld AH,de Kleijn DP,Roholl PJ,Fontijn J,Plomp S,Borst C

更新日期：2001-07-01 00:00:00

abstract：:Dyslipidemias are strongly linked to the development of atherosclerotic cardiovascular disease. Most dyslipidemias find their origin in the liver. In recent years, the differentiation of induced pluripotent stem cells (iPSCs) into hepatocyte-like cells has provided a versatile platform for the functional study of vari...

journal_title：Atherosclerosis

authors： Larsen LE,Smith MA,Abbey D,Korn A,Reeskamp LF,Hand NJ,Holleboom AG

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Tumour necrosis factor alpha (TNFalpha) is a pro-inflammatory cytokine implicated in atherosclerotic plaque formation. We investigated whether circulating TNFalpha is prospectively associated with myocardial infarction (MI) or stroke in the older general population, independently of established cardiovascula...

journal_title：Atherosclerosis

authors： Jefferis BJ,Whincup PH,Welsh P,Wannamethee SG,Rumley A,Lennon LT,Thomson AG,Carson C,Ebrahim S,Lowe GD

更新日期：2009-07-01 00:00:00

abstract：:Human serum paraoxonase (PON1) is an HDL-associated enzyme involved in the protection of lipoproteins from oxidation. A polymorphism at position 192 (Gln/Arg) influences its activity in a substrate-dependent manner. The aim of the present study was to evaluate, in vivo, the contribution of the PON1-192 polymorphism to...

journal_title：Atherosclerosis

authors： Gnasso A,Motti C,Irace C,Di Gennaro I,Pujia A,Leto E,Ciamei M,Crivaro A,Bernardini S,Federici G,Cortese C

更新日期：2002-10-01 00:00:00

abstract：:Aging, which is an independent risk factor for heart disease, alters body fat mass and its function. Epicardial fat plays an important physiological and pathophysiological role on cardiac structure and function. This study investigated if aging altered the abundance of epicardial (EF) and abdominal fat (AF) derived me...

journal_title：Atherosclerosis

authors： Fei J,Cook C,Blough E,Santanam N

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:This systematic literature review sought to determine the effects of carotid atherosclerotic plaque on local arterial stiffness. METHODS:MedLine, EMBASE, and grey literature were searched with the following term: ("atherosclerosis" or "carotid atherosclerosis" or "carotid artery disease" or "carotid plaque")...

journal_title：Atherosclerosis

authors： Boesen ME,Singh D,Menon BK,Frayne R

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND AND PURPOSES:Pulse wave analysis (PWV), a marker of aortic stiffness, has independent predictive value for cardiovascular morbidity and mortality in both healthy and high-risk populations, especially fatal stroke, and for long-term functional stroke prognosis. Whether arterial stiffness and wave reflection a...

journal_title：Atherosclerosis

authors： Gąsecki D,Rojek A,Kwarciany M,Kowalczyk K,Boutouyrie P,Nyka W,Laurent S,Narkiewicz K

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Studying atherosclerotic calcification in vivo requires mouse models with genetic modifications. Previous studies showed that injection of recombinant adeno-associated virus vector (AAV) encoding a gain-of-function mutant PCSK9 into mice promotes atherosclerosis. We aimed to study cardiovascular cal...

journal_title：Atherosclerosis

authors： Goettsch C,Hutcheson JD,Hagita S,Rogers MA,Creager MD,Pham T,Choi J,Mlynarchik AK,Pieper B,Kjolby M,Aikawa M,Aikawa E

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:Recent reports of animal models have shown that growth factors have stimulating effect on brain perfusion via the development of blood vessels. However, studies on the effect of growth factors on brain perfusion in humans are lacking. The aim of our study was to prospectively investigate in humans the relatio...

journal_title：Atherosclerosis

authors： van Laar PJ,van Raamt AF,van der Grond J,Mali WPTM,van der Graaf Y,Hendrikse J,SMART Study Group.

更新日期：2008-01-01 00:00:00

abstract：:Male and female rats kept on a long-term atherogenic regimen for periods up to 15 months developed marked atherosclerotic changes of cardiac valves in 100% of cases. The degree and the topography of valvular atherosclerotic plaques corresponded widely to that seen in human atherosclerotic valvular disease. The regular...

journal_title：Atherosclerosis

authors： Záhor Z,Czabanová V

更新日期：1977-05-01 00:00:00

abstract：:Lack of physical activity appears to have deleterious effects on serum lipoproteins. Twenty-three patients who were completely immobilised by traumatic fracture of the spine had significantly lower (P < 0.001) plasma high density lipoprotein cholesterol (HDL-C) and apolipoprotein A-I levels than normally mobile paired...

journal_title：Atherosclerosis

authors： Nikkilä EA,Kuusi T,Myllynen P

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND AND AIMS:South Asians are at increased risk for cardiovascular disease (CVD). Aortic valve calcium (AVC) is associated with CVD risk and aortic stenosis. Elevated Lp(a) is a heritable risk factor for CVD and AVC. AVC prevalence and its association with Lp(a) have not been studied in South Asians. METHODS:Am...

journal_title：Atherosclerosis

authors： Makshood M,Joshi PH,Kanaya AM,Ayers C,Budoff M,Tsai MY,Blaha M,Michos ED,Post WS

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Observations in the past have hypothesized an association between body iron status and coronary heart disease (CHD). Epidemiological studies to date have however been inconclusive without the existence of strongly positive or strongly negative associations between iron status and coronary heart disease. OBJ...

journal_title：Atherosclerosis

authors： Das De S,Krishna S,Jethwa A

更新日期：2015-02-01 00:00:00

abstract：:Whether an association, causative or not, exists between the level of serum selenium and the risk of ischaemic heart disease (IHD) remains unsettled. We investigated the issue in a cohort of 3387 males aged 53-74 years (mean 63). Based on information about health status, life-style and socioeconomic factors given in a...

journal_title：Atherosclerosis

authors： Suadicani P,Hein HO,Gyntelberg F

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Low ankle-brachial index (ABI) is associated with increased mortality and an increased incidence of cardiovascular events. The purpose of this study was to investigate the value of borderline ABI in predicting clinical outcomes. METHODS AND RESULTS:The data were derived from the Shinken Database 20...

journal_title：Atherosclerosis

authors： Tanaka S,Kaneko H,Kano H,Matsuno S,Suzuki S,Takai H,Otsuka T,Uejima T,Oikawa Y,Nagashima K,Kirigaya H,Sagara K,Yajima J,Sawada H,Aizawa T,Yamashita T

更新日期：2016-07-01 00:00:00

abstract：:Cardiovascular disease (CVD) is currently the second most frequent cause of death (after cancer) among HIV-positive subjects. The clinical use of highly active antiretroviral therapy (HAART) has dramatically reduced mortality and morbidity in HIV-positive population, leading to prolonged and improved quality of life. ...

journal_title：Atherosclerosis

authors： Giannarelli C,Klein RS,Badimon JJ

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVES:To examine the longitudinal association between toenail selenium levels and subclinical atherosclerosis over an 18-year period. METHODS:Toenail selenium concentrations were examined among 3112 Americans age 20-32 years in 1987 and measured by instrumental neutron-activation analysis. Subclinical atheroscler...

journal_title：Atherosclerosis

authors： Xun P,Liu K,Morris JS,Daviglus ML,He K

更新日期：2010-06-01 00:00:00

abstract：:Apolipoprotein E (apoE) exerts prominent anti-inflammatory effects and undergoes recycling by target cells. We previously reported that the peptide Ac-hE18A-NH(2), composed of the receptor binding domain (LRKLRKRLLR) of apoE covalently linked to the Class A amphipathic peptide 18A, dramatically lowers plasma cholester...

journal_title：Atherosclerosis

authors： Datta G,White CR,Dashti N,Chaddha M,Palgunachari MN,Gupta H,Handattu SP,Garber DW,Anantharamaiah GM

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Several risk prediction models for coronary heart disease (CHD) are available today, however, they only explain a modest proportion of the incidence. Circulating microRNAs (miRs) have recently been associated with processes in CHD development, and may therefore represent new potential risk markers. ...

journal_title：Atherosclerosis

authors： Velle-Forbord T,Eidlaug M,Debik J,Sæther JC,Follestad T,Nauman J,Gigante B,Røsjø H,Omland T,Langaas M,Bye A

更新日期：2019-10-01 00:00:00

abstract：:Dietary plant proteins may lower plasma cholesterol and LDL concentrations in hypercholesterolemic patients when substituted for animal proteins, particularly in diets with low cholesterol and saturated fat content. Plant protein diets appear, however, to be without effect on plasma lipoprotein levels in normal subjec...

journal_title：Atherosclerosis

authors： Meinertz H,Faergeman O,Nilausen K,Chapman MJ,Goldstein S,Laplaud PM

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Circulating levels of adhesion molecules increase in various inflammation-related diseases, such as atherosclerosis. However, data about factors influencing their concentrations in physiological conditions are scarce. METHODS:We have studied the determinants of serum levels of intercellular adhesion molecul...

journal_title：Atherosclerosis

authors： Ponthieux A,Herbeth B,Droesch S,Haddy N,Lambert D,Visvikis S

更新日期：2004-02-01 00:00:00

abstract：:We examined cross-sectional associations between sex hormones and carotid artery intimal-medial thickness (cIMT) and coronary artery calcium in women in the Multi-Ethnic Study of Atherosclerosis. Serum testosterone, estradiol, sex hormone binding globulin (SHBG), and dehydroepiandrosterone levels were measured in 1947...

journal_title：Atherosclerosis

authors： Ouyang P,Vaidya D,Dobs A,Golden SH,Szklo M,Heckbert SR,Kopp P,Gapstur SM

更新日期：2009-05-01 00:00:00

abstract：:We investigated the influence of fish oil on cholesterol induced atherosclerosis in rabbits. Group I, a control group was fed a cholesterol-free diet, group II was fed a diet supplemented with 1.5% cholesterol, group III received in addition to cholesterol supplementation a purified fish oil concentrate (Maxepa, 2 ml/...

journal_title：Atherosclerosis

authors： Thiery J,Seidel D

更新日期：1987-01-01 00:00:00

abstract：AIMS:Inhibition of the classical renin-angiotensin system (RAS) has been proved to reduce atherosclerosis. Recently, angiotensin-(1-7) [Ang-(1-7)], a new component of RAS, has been shown to attenuate atherosclerosis formation. However, direct comparison of Ang-(1-7) and angiotensin II type 1 receptor blocker (ARB) on a...

journal_title：Atherosclerosis

authors： Yang J,Sun Y,Dong M,Yang X,Meng X,Niu R,Guan J,Zhang Y,Zhang C

更新日期：2015-06-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) can overcome a potential anti-angiogenic effect of TNF-alpha by inhibiting endothelial apoptosis induced by this cytokine. Soluble TNF-alpha receptor I (sTNFRI) is an extracellular domain of TNFRI and antagonizes the activity of TNF-alpha. Here we report that sTNFRI is able to...

journal_title：Atherosclerosis

authors： Sugano M,Tsuchida K,Tomita H,Makino N

更新日期：2002-05-01 00:00:00

abstract：:Whole blood and plasma viscosity, red cell aggregability and deformability, and plasma fibrinogen have been compared between 20 patients with heterozygous familial hypercholesterolaemia (FH), without clinical arterial disease, and 20 age- and sex-matched controls. Plasma fibrinogen was elevated in FH, associated with ...

journal_title：Atherosclerosis

authors： Jay RH,Rampling MW,Betteridge DJ

更新日期：1990-12-01 00:00:00